{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T05:48:58Z","timestamp":1779342538851,"version":"3.51.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[1997,3,1]],"date-time":"1997-03-01T00:00:00Z","timestamp":857174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,10]],"date-time":"2020-10-10T00:00:00Z","timestamp":1602288000000},"content-version":"vor","delay-in-days":8624,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1997,3]]},"DOI":"10.1074\/jbc.272.10.6114","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:57:46Z","timestamp":1027695466000},"page":"6114-6118","source":"Crossref","is-referenced-by-count":65,"title":["Mutation of Glu-361 in Human Endothelial Nitric-oxide Synthase Selectively Abolishes L-Arginine Binding without Perturbing the Behavior of Heme and Other Redox Centers"],"prefix":"10.1016","volume":"272","author":[{"given":"Pei-Feng","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ah-Lim","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Berka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth K.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.272.10.6114_bib1","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1073\/pnas.87.2.682","volume":"87","author":"Bredt","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.10.6114_bib2","doi-asserted-by":"crossref","first-page":"10480","DOI":"10.1073\/pnas.88.23.10480","volume":"88","author":"Pollock","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.10.6114_bib3","doi-asserted-by":"crossref","first-page":"6259","DOI":"10.1016\/S0021-9258(18)38112-2","volume":"266","author":"Stuehr","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib4","doi-asserted-by":"crossref","first-page":"15147","DOI":"10.1016\/S0021-9258(17)36585-7","volume":"269","author":"Sheta","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib5","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1021\/bi00003a013","volume":"34","author":"Ghosh","year":"1995","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib6","doi-asserted-by":"crossref","first-page":"3683","DOI":"10.1021\/bi00011a025","volume":"34","author":"McMillan","year":"1995","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib7","doi-asserted-by":"crossref","first-page":"11316","DOI":"10.1021\/bi00036a003","volume":"34","author":"Ghosh","year":"1995","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib8","doi-asserted-by":"crossref","first-page":"14631","DOI":"10.1074\/jbc.271.24.14631","volume":"271","author":"Chen","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib9","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/351714a0","volume":"351","author":"Bredt","year":"1991","journal-title":"Nature"},{"key":"10.1074\/jbc.272.10.6114_bib10","doi-asserted-by":"crossref","first-page":"10769","DOI":"10.1073\/pnas.90.22.10769","volume":"90","author":"Abu-Soud","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.10.6114_bib11","doi-asserted-by":"crossref","first-page":"20335","DOI":"10.1016\/S0021-9258(17)31996-8","volume":"269","author":"Matsouka","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib12","doi-asserted-by":"crossref","first-page":"11141","DOI":"10.1073\/pnas.89.23.11141","volume":"89","author":"McMillan","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.10.6114_bib13","doi-asserted-by":"crossref","first-page":"25062","DOI":"10.1016\/S0021-9258(17)31498-9","volume":"269","author":"Chen","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib14","doi-asserted-by":"crossref","first-page":"14723","DOI":"10.1021\/bi00253a010","volume":"33","author":"Richards","year":"1994","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib15","doi-asserted-by":"crossref","first-page":"3686","DOI":"10.1021\/bi00011a025","volume":"34","author":"McMillan","year":"1995","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib16","doi-asserted-by":"crossref","first-page":"7204","DOI":"10.1021\/bi960087u","volume":"35","author":"Sari","year":"1996","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib17","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1006\/bbrc.1995.1659","volume":"210","author":"Nishimura","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.10.6114_bib18","doi-asserted-by":"crossref","first-page":"26669","DOI":"10.1016\/S0021-9258(18)47071-8","volume":"269","author":"Garvey","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib19","doi-asserted-by":"crossref","first-page":"26677","DOI":"10.1016\/S0021-9258(18)47072-X","volume":"269","author":"Furfine","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib20","doi-asserted-by":"crossref","first-page":"33293","DOI":"10.1074\/jbc.271.52.33293","volume":"271","author":"Berka","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib21","doi-asserted-by":"crossref","first-page":"5463","DOI":"10.1073\/pnas.74.12.5463","volume":"74","author":"Sanger","year":"1977","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.10.6114_bib22","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1006\/bbrc.1995.2579","volume":"215","author":"Chen","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.10.6114_bib23","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1016\/S0021-9258(17)42080-1","volume":"269","author":"Klatt","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib24","doi-asserted-by":"crossref","first-page":"9875","DOI":"10.1021\/bi00089a001","volume":"32","author":"McMillan","year":"1993","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib25","doi-asserted-by":"crossref","first-page":"8554","DOI":"10.1016\/S0021-9258(18)52911-2","volume":"268","author":"Tsai","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib26","doi-asserted-by":"crossref","first-page":"32563","DOI":"10.1074\/jbc.271.51.32563","volume":"271","author":"Tsai","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib27","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/0076-6879(93)27015-9","volume":"227","author":"Hales","year":"1993","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.272.10.6114_bib28","doi-asserted-by":"crossref","first-page":"14519","DOI":"10.1016\/S0021-9258(18)42066-2","volume":"267","author":"Janssens","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0014-5793(93)81210-Q","volume":"316","author":"Nakane","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.272.10.6114_bib30","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1073\/pnas.90.8.3491","volume":"90","author":"Geller","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.10.6114_bib31","doi-asserted-by":"crossref","first-page":"20547","DOI":"10.1016\/S0021-9258(19)36718-3","volume":"267","author":"Stuehr","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib32","doi-asserted-by":"crossref","first-page":"5883","DOI":"10.1021\/bi952844e","volume":"35","author":"Sennequier","year":"1996","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.10.6114_bib33","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/0006-291X(90)92343-X","volume":"168","author":"Fukuto","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.10.6114_bib34","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1476-5381.1991.tb12159.x","volume":"102","author":"McCall","year":"1991","journal-title":"Br. J. Pharmacol."},{"key":"10.1074\/jbc.272.10.6114_bib35","doi-asserted-by":"crossref","first-page":"26083","DOI":"10.1016\/S0021-9258(18)47162-1","volume":"269","author":"Frey","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.10.6114_bib36","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1021\/jm00022a001","volume":"38","author":"Kerwin","year":"1995","journal-title":"J. Med. Chem."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818411155?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818411155?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.272.10.6114","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T08:25:24Z","timestamp":1641025524000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818411155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,3]]},"references-count":36,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1997,3]]}},"alternative-id":["S0021925818411155"],"URL":"https:\/\/doi.org\/10.1074\/jbc.272.10.6114","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1997,3]]}}}