{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:13:59Z","timestamp":1791242039126,"version":"4.1.0"},"reference-count":68,"publisher":"Elsevier BV","issue":"27","license":[{"start":{"date-parts":[[1997,7,1]],"date-time":"1997-07-01T00:00:00Z","timestamp":867715200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,10]],"date-time":"2020-10-10T00:00:00Z","timestamp":1602288000000},"content-version":"vor","delay-in-days":8502,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1997,7]]},"DOI":"10.1074\/jbc.272.27.16873","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:47:21Z","timestamp":1027694841000},"page":"16873-16883","source":"Crossref","is-referenced-by-count":77,"title":["Genomic Organization of the 3\u2032 Region of the Human Mucin GeneMUC5B"],"prefix":"10.1016","volume":"272","author":[{"given":"Jean-Luc","family":"Desseyn","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Pierre","family":"Aubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Van Seuningen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Porchet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Laine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.272.27.16873_bib1","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1146\/annurev.ph.57.030195.003135","volume":"57","author":"Gendler","year":"1995","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.272.27.16873_bib2","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1146\/annurev.ph.57.030195.003223","volume":"57","author":"Bansil","year":"1995","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.272.27.16873_bib3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1146\/annurev.ph.57.030195.003101","volume":"57","author":"Forstner","year":"1995","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.272.27.16873_bib4","first-page":"151","volume":"14","author":"Verma","year":"1994","journal-title":"Cancer Biochem. Biophys."},{"key":"10.1074\/jbc.272.27.16873_bib5","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/0016-5085(95)90380-1","volume":"109","author":"Ho","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1074\/jbc.272.27.16873_bib6","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1053\/gast.1996.v110.pm8536891","volume":"110","author":"Buisine","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1074\/jbc.272.27.16873_bib7","first-page":"612","volume":"134","author":"Kaliner","year":"1986","journal-title":"Am. Rev. Respir. Dis."},{"key":"10.1074\/jbc.272.27.16873_bib8","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1172\/JCI110209","volume":"67","author":"Lee","year":"1981","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.272.27.16873_bib9","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/00042737-199304000-00007","volume":"5","author":"Klinkskpoor","year":"1993","journal-title":"Eur. J. Gastroenterol. Hepatol."},{"key":"10.1074\/jbc.272.27.16873_bib10","doi-asserted-by":"crossref","first-page":"15294","DOI":"10.1016\/S0021-9258(18)77255-4","volume":"265","author":"Lan","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib11","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/S0006-291X(05)80888-5","volume":"173","author":"Lancaster","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.27.16873_bib12","doi-asserted-by":"crossref","first-page":"20563","DOI":"10.1016\/S0021-9258(20)80762-5","volume":"268","author":"Bobek","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib13","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1006\/geno.1996.0049","volume":"31","author":"Bobek","year":"1996","journal-title":"Genomics"},{"key":"10.1074\/jbc.272.27.16873_bib14","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.1016\/S0021-9258(18)83373-7","volume":"264","author":"Gum","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib15","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1172\/JCI115360","volume":"88","author":"Toribara","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.272.27.16873_bib16","doi-asserted-by":"crossref","first-page":"21375","DOI":"10.1016\/S0021-9258(19)36620-7","volume":"267","author":"Gum","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib17","doi-asserted-by":"crossref","first-page":"2440","DOI":"10.1016\/S0021-9258(17)41965-X","volume":"269","author":"Gum","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib18","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/0006-291X(90)91408-K","volume":"171","author":"Gum","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.27.16873_bib19","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1016\/0006-291X(91)91580-6","volume":"175","author":"Porchet","year":"1991","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.27.16873_bib20","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1165\/ajrcmb\/5.2.178","volume":"5","author":"Aubert","year":"1991","journal-title":"Am. J. Respir. Cell. Mol. Biol."},{"key":"10.1074\/jbc.272.27.16873_bib21","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1042\/bj3050211","volume":"305","author":"Guyonnet Dup\u00e9rat","year":"1995","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.272.27.16873_bib22","doi-asserted-by":"crossref","first-page":"12932","DOI":"10.1016\/S0021-9258(18)99965-5","volume":"269","author":"Meerzaman","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib23","doi-asserted-by":"crossref","first-page":"13665","DOI":"10.1074\/jbc.270.23.13665","volume":"270","author":"Lesuffleur","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib24","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1042\/bj3080831","volume":"308","author":"Klomp","year":"1995","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.272.27.16873_bib25","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1042\/bj2930329","volume":"293","author":"Dufoss\u00e9","year":"1993","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.272.27.16873_bib26","doi-asserted-by":"crossref","first-page":"5879","DOI":"10.1016\/S0021-9258(18)53402-5","volume":"268","author":"Toribara","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib27","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/BF00197699","volume":"86","author":"Nguyen","year":"1990","journal-title":"Hum. Genet."},{"key":"10.1074\/jbc.272.27.16873_bib28","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1469-1809.1990.tb00383.x","volume":"54","author":"Griffiths","year":"1990","journal-title":"Ann. Hum. Genet."},{"key":"10.1074\/jbc.272.27.16873_bib29","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1006\/geno.1996.0637","volume":"38","author":"Pigny","year":"1996","journal-title":"Genomics"},{"key":"10.1074\/jbc.272.27.16873_bib30","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1074\/jbc.272.6.3168","volume":"272","author":"Desseyn","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib31","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1177\/41.10.8245407","volume":"41","author":"Audi\u00e9","year":"1993","journal-title":"J. Histochem. Cytochem."},{"key":"10.1074\/jbc.272.27.16873_bib32","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1093\/humrep\/10.1.98","volume":"10","author":"Audi\u00e9","year":"1995","journal-title":"Hum. Reprod."},{"key":"10.1074\/jbc.272.27.16873_bib33","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/0016-5085(94)90767-6","volume":"106","author":"Balagu\u00e9","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1074\/jbc.272.27.16873_bib34","first-page":"223","volume":"21","author":"Campion","year":"1995","journal-title":"Hepatol."},{"key":"10.1074\/jbc.272.27.16873_bib35","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/0016-5085(95)90406-9","volume":"109","author":"Balagu\u00e9","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1074\/jbc.272.27.16873_bib36","doi-asserted-by":"crossref","first-page":"19514","DOI":"10.1016\/S0021-9258(19)47144-5","volume":"264","author":"Mancuso","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib37","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1006\/bbrc.1995.2884","volume":"217","author":"Troxler","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.27.16873_bib38","doi-asserted-by":"crossref","first-page":"471","DOI":"10.3233\/BIR-1990-273-426","volume":"27","author":"Cr\u00e9pin","year":"1991","journal-title":"Biorheology"},{"key":"10.1074\/jbc.272.27.16873_bib39","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1021\/bi00709a025","volume":"13","author":"Glisin","year":"1974","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.27.16873_bib40","doi-asserted-by":"crossref","first-page":"5463","DOI":"10.1073\/pnas.74.12.5463","volume":"74","author":"Sanger","year":"1977","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.27.16873_bib41","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0092-8674(85)80007-6","volume":"41","author":"Birnstiel","year":"1985","journal-title":"Cell"},{"key":"10.1074\/jbc.272.27.16873_bib42","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/309179a0","volume":"309","author":"Berget","year":"1984","journal-title":"Nature"},{"key":"10.1074\/jbc.272.27.16873_bib43","doi-asserted-by":"crossref","first-page":"9893","DOI":"10.1093\/nar\/16.21.9893","volume":"16","author":"Hawkins","year":"1988","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.272.27.16873_bib44","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1093\/nar\/10.2.459","volume":"10","author":"Mount","year":"1982","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.272.27.16873_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1600-0714.1982.tb00138.x","volume":"11","author":"Tabak","year":"1982","journal-title":"J. Oral Pathol."},{"key":"10.1074\/jbc.272.27.16873_bib46","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0003-9861(87)90366-3","volume":"258","author":"Loomis","year":"1987","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.272.27.16873_bib47","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1021\/bi00699a001","volume":"13","author":"Chou","year":"1974","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.27.16873_bib48","doi-asserted-by":"crossref","first-page":"12170","DOI":"10.1016\/S0021-9258(20)71335-9","volume":"259","author":"Smith","year":"1984","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib49","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1172\/JCI111991","volume":"76","author":"Smith","year":"1985","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.272.27.16873_bib50","doi-asserted-by":"crossref","first-page":"26025","DOI":"10.1074\/jbc.270.44.26025","volume":"270","author":"Hardy","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib51","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1042\/bj2561059","volume":"256","author":"Baker","year":"1988","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.272.27.16873_bib52","doi-asserted-by":"crossref","first-page":"3531","DOI":"10.1073\/pnas.89.8.3531","volume":"89","author":"Mayadas","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.27.16873_bib53","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1083\/jcb.113.1.195","volume":"113","author":"Voorberg","year":"1991","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.272.27.16873_bib54","doi-asserted-by":"crossref","first-page":"9845","DOI":"10.1074\/jbc.271.16.9845","volume":"271","author":"Perez-Vilar","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.272.27.16873_bib55","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0003-9969(90)90041-8","volume":"35","author":"Kawagishi","year":"1990","journal-title":"Arch. Oral Biol."},{"key":"10.1074\/jbc.272.27.16873_bib56","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1042\/bj2610637","volume":"261","author":"Roberton","year":"1989","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.272.27.16873_bib57","doi-asserted-by":"crossref","first-page":"6240","DOI":"10.1021\/bi00478a018","volume":"29","author":"Probst","year":"1990","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.272.27.16873_bib58","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1042\/bst0230805","volume":"23","author":"Hoffmann","year":"1995","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.272.27.16873_bib59","first-page":"G613","volume":"269","author":"Van Klinken","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.272.27.16873_bib60","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1146\/annurev.bb.24.060195.001413","volume":"24","author":"Sun","year":"1995","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"10.1074\/jbc.272.27.16873_bib61","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/ng1293-376","volume":"5","author":"Meitinger","year":"1993","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.272.27.16873_bib62","first-page":"465","volume":"105B","author":"Hoffmann","year":"1993","journal-title":"Comp. Biochem. Physiol."},{"key":"10.1074\/jbc.272.27.16873_bib64","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1073\/pnas.80.9.2738","volume":"80","author":"Lynch","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.272.27.16873_bib65","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1083\/jcb.102.4.1320","volume":"102","author":"Wagner","year":"1986","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.272.27.16873_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0014-5793(87)80002-9","volume":"214","author":"Patthy","year":"1987","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.272.27.16873_bib67","first-page":"383","volume":"4","author":"Bork","year":"1992","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1074\/jbc.272.27.16873_bib68","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1006\/bbrc.1996.0378","volume":"220","author":"Pigny","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.272.27.16873_bib63","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1101\/gad.8.2.133","volume":"8","author":"Kingsley","year":"1994","journal-title":"Genes Dev."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818393049?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818393049?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.272.27.16873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,31]],"date-time":"2021-12-31T23:42:38Z","timestamp":1640994158000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818393049"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,7]]},"references-count":68,"journal-issue":{"issue":"27","published-print":{"date-parts":[[1997,7]]}},"alternative-id":["S0021925818393049"],"URL":"https:\/\/doi.org\/10.1074\/jbc.272.27.16873","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1997,7]]}}}