{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T12:30:55Z","timestamp":1791462655699,"version":"4.3.4"},"reference-count":23,"publisher":"Elsevier BV","issue":"30","license":[{"start":{"date-parts":[[1998,7,1]],"date-time":"1998-07-01T00:00:00Z","timestamp":899251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T00:00:00Z","timestamp":1602892800000},"content-version":"vor","delay-in-days":8144,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1998,7]]},"DOI":"10.1074\/jbc.273.30.19086","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:02:22Z","timestamp":1027695742000},"page":"19086-19092","source":"Crossref","is-referenced-by-count":276,"title":["Targeted Disruption of the Acid \u03b1-Glucosidase Gene in Mice Causes an Illness with Critical Features of Both Infantile and Adult Human Glycogen Storage Disease Type II"],"prefix":"10.1016","volume":"273","author":[{"given":"Nina","family":"Raben","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanneboyina","family":"Nagaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eunice","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Kessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry","family":"Byrne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"LaMarca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"King","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerrold","family":"Ward","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Sauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Plotz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.273.30.19086_bib1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1093\/hmg\/7.1.53","volume":"7","author":"Bijvoet","year":"1998","journal-title":"Hum Mol Genet"},{"key":"10.1074\/jbc.273.30.19086_bib2","series-title":"The Metabolic and Molecular Basis of Inherited Disease","first-page":"2443","author":"Hirschhorn","year":"1995"},{"key":"10.1074\/jbc.273.30.19086_bib3","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1203\/00006450-198807000-00021","volume":"24","author":"van der Ploeg","year":"1988","journal-title":"Pediatr. Res."},{"key":"10.1074\/jbc.273.30.19086_bib4","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1172\/JCI115025","volume":"87","author":"van der Ploeg","year":"1991","journal-title":"J Clin. Invest."},{"key":"10.1074\/jbc.273.30.19086_bib5","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1146\/annurev.bi.60.070191.001353","volume":"60","author":"Neufeld","year":"1991","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.273.30.19086_bib6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/BF00314479","volume":"235","author":"van der Ploeg","year":"1988","journal-title":"J Neurol."},{"key":"10.1074\/jbc.273.30.19086_bib7","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1073\/pnas.93.1.65","volume":"93","author":"van Hove","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.273.30.19086_bib8","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1089\/hum.1997.8.13-1555","volume":"8","author":"Zaretsky","year":"1997","journal-title":"Hum. Gene Ther."},{"key":"10.1074\/jbc.273.30.19086_bib9","doi-asserted-by":"crossref","first-page":"14082","DOI":"10.1073\/pnas.93.24.14082","volume":"93","author":"Kessler","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.273.30.19086_bib10","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0167-4781(96)00093-0","volume":"1308","author":"Bijvoet","year":"1996","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.273.30.19086_bib11","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/sj.gt.3300609","volume":"5","author":"Pauly","year":"1998","journal-title":"Gene Therapy"},{"key":"10.1074\/jbc.273.30.19086_bib12","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1172\/JCI1722","volume":"101","author":"Kikuchi","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.273.30.19086_bib13","doi-asserted-by":"crossref","first-page":"5166","DOI":"10.1073\/pnas.85.14.5166","volume":"85","author":"Sauer","year":"1988","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.273.30.19086_bib14","doi-asserted-by":"crossref","first-page":"9975","DOI":"10.1073\/pnas.91.21.9975","volume":"91","author":"Yamanaka","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.273.30.19086_bib15","doi-asserted-by":"crossref","first-page":"13507","DOI":"10.1016\/S0021-9258(18)92727-4","volume":"266","author":"Hermans","year":"1991","journal-title":"J Biol. Chem."},{"key":"10.1074\/jbc.273.30.19086_bib16","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/(SICI)1098-1004(1997)10:2<128::AID-HUMU5>3.0.CO;2-G","volume":"10","author":"Adams","year":"1997","journal-title":"Hum Mutat."},{"key":"10.1074\/jbc.273.30.19086_bib17","doi-asserted-by":"crossref","first-page":"9641","DOI":"10.1073\/pnas.83.24.9641","volume":"83","author":"Martiniuk","year":"1986","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.273.30.19086_bib18","doi-asserted-by":"crossref","first-page":"5860","DOI":"10.1073\/pnas.93.12.5860","volume":"93","author":"Lakso","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.273.30.19086_bib19","doi-asserted-by":"crossref","first-page":"S61","DOI":"10.1002\/mus.880181414","volume":"3","author":"Reuser","year":"1995","journal-title":"Muscle Nerve"},{"key":"10.1074\/jbc.273.30.19086_bib20","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1136\/jmg.32.10.836-a","volume":"32","author":"Kroos","year":"1995","journal-title":"J Med. Genet"},{"key":"10.1074\/jbc.273.30.19086_bib21","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1002\/mus.880181415","volume":"3","author":"Raben","year":"1995","journal-title":"Muscle Nerve"},{"key":"10.1074\/jbc.273.30.19086_bib22","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1002\/bies.950181209","volume":"18","author":"Erickson","year":"1996","journal-title":"Bioessays"},{"key":"10.1074\/jbc.273.30.19086_bib23","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1172\/JCI118527","volume":"97","author":"Wilson","year":"1996","journal-title":"J. Clin. Invest."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818802423?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818802423?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.273.30.19086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T02:45:33Z","timestamp":1641091533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818802423"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,7]]},"references-count":23,"journal-issue":{"issue":"30","published-print":{"date-parts":[[1998,7]]}},"alternative-id":["S0021925818802423"],"URL":"https:\/\/doi.org\/10.1074\/jbc.273.30.19086","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1998,7]]}}}