{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T13:13:37Z","timestamp":1760706817549},"reference-count":43,"publisher":"Elsevier BV","issue":"42","license":[{"start":{"date-parts":[[1998,10,1]],"date-time":"1998-10-01T00:00:00Z","timestamp":907200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":8035,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1998,10]]},"DOI":"10.1074\/jbc.273.42.27076","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:02:22Z","timestamp":1027695742000},"page":"27076-27083","source":"Crossref","is-referenced-by-count":40,"title":["\u03b4-Atracotoxins from Australian Funnel-web Spiders Compete with Scorpion \u03b1-Toxin Binding but Differentially Modulate Alkaloid Toxin Activation of Voltage-gated Sodium Channels"],"prefix":"10.1016","volume":"273","author":[{"given":"Michelle J.","family":"Little","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathy","family":"Zappia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Gilles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Connor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret I.","family":"Tyler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie-France","family":"Martin-Eauclaire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dalia","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham M.","family":"Nicholson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.273.42.27076_bib1","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/nsb0797-559","volume":"4","author":"Fletcher","year":"1997","journal-title":"Nat. Struct. Biol."},{"key":"10.1074\/jbc.273.42.27076_bib2","article-title":"Perspectives in Drug Discovery and Design: Animal Toxins and Potassium Channels","author":"Fletcher","year":"1998"},{"key":"10.1074\/jbc.273.42.27076_bib3","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1042\/bj2500401","volume":"250","author":"Brown","year":"1988","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.273.42.27076_bib4","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/0014-5793(85)81132-7","volume":"181","author":"Sheumack","year":"1985","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.273.42.27076_bib5","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1007\/BF00724524","volume":"428","author":"Nicholson","year":"1994","journal-title":"Pfluegers Arch."},{"key":"10.1074\/jbc.273.42.27076_bib6","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s004240050612","volume":"436","author":"Nicholson","year":"1998","journal-title":"Pfluegers Arch."},{"key":"10.1074\/jbc.273.42.27076_bib7","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1146\/annurev.bi.55.070186.004513","volume":"55","author":"Catterall","year":"1986","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.273.42.27076_bib8","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1016\/S0969-2126(97)00301-8","volume":"5","author":"Fletcher","year":"1997","journal-title":"Structure"},{"key":"10.1074\/jbc.273.42.27076_bib9","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0014-5793(97)01452-X","volume":"419","author":"Pallaghy","year":"1997","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.273.42.27076_bib10","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1002\/pro.5560031022","volume":"3","author":"Pallaghy","year":"1993","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.273.42.27076_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0041-0101(82)90137-4","volume":"20","author":"Fontecilla-Camps","year":"1982","journal-title":"Toxicon"},{"key":"10.1074\/jbc.273.42.27076_bib12","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1021\/bi961497l","volume":"36","author":"Tugarinov","year":"1997","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.273.42.27076_bib13","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1085\/jgp.88.3.413","volume":"88","author":"Strichartz","year":"1986","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.273.42.27076_bib14","doi-asserted-by":"crossref","first-page":"5941","DOI":"10.1021\/bi00477a009","volume":"29","author":"Eitan","year":"1990","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.273.42.27076_bib15","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1016\/S0021-9258(17)41983-1","volume":"269","author":"Fainzilber","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.273.42.27076_bib16","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1124\/mol.51.4.651","volume":"51","author":"Trainer","year":"1997","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.273.42.27076_bib17","series-title":"Toxins and Signal Transduction","first-page":"119","author":"Gordon","year":"1997"},{"key":"10.1074\/jbc.273.42.27076_bib18","first-page":"109","volume":"41","author":"Hille","year":"1987","journal-title":"Soc. Gen. Physiol. Ser."},{"key":"10.1074\/jbc.273.42.27076_bib19","series-title":"Ionic Channels of Excitable Membranes","first-page":"308","author":"Hille","year":"1992"},{"key":"10.1074\/jbc.273.42.27076_bib20","doi-asserted-by":"crossref","first-page":"8669","DOI":"10.1016\/S0021-9258(19)75273-9","volume":"252","author":"Catterall","year":"1977","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.273.42.27076_bib21","doi-asserted-by":"crossref","first-page":"7307","DOI":"10.1016\/S0021-9258(17)34501-5","volume":"253","author":"Ray","year":"1978","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.273.42.27076_bib22","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1432-1033.1970.tb01111.x","volume":"16","author":"Miranda","year":"1970","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.273.42.27076_bib23","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0041-0101(98)00080-4","volume":"36","author":"Sauti\u00e8re","year":"1998","journal-title":"Toxicon"},{"key":"10.1074\/jbc.273.42.27076_bib24","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1111\/j.1469-7793.1998.047bo.x","volume":"509","author":"Connor","year":"1998","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.273.42.27076_bib25","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1124\/mol.52.1.136","volume":"52","author":"Ingram","year":"1997","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.273.42.27076_bib26","first-page":"79","volume":"96","author":"Gray","year":"1962","journal-title":"J. Anat."},{"key":"10.1074\/jbc.273.42.27076_bib27","first-page":"78","volume":"19","author":"Tamkun","year":"1981","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.273.42.27076_bib28","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1021\/bi00600a011","volume":"17","author":"Kanner","year":"1978","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.273.42.27076_bib29","doi-asserted-by":"crossref","first-page":"8922","DOI":"10.1016\/S0021-9258(19)52487-5","volume":"256","author":"Catterall","year":"1981","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.273.42.27076_bib30","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0014-5793(93)81147-R","volume":"315","author":"Gordon","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.273.42.27076_bib31","doi-asserted-by":"crossref","first-page":"8034","DOI":"10.1074\/jbc.271.14.8034","volume":"271","author":"Gordon","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.273.42.27076_bib32","doi-asserted-by":"crossref","first-page":"15153","DOI":"10.1074\/jbc.270.25.15153","volume":"270","author":"Cest\u00e8le","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.273.42.27076_bib33","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1016\/0006-2952(73)90196-2","volume":"22","author":"Cheng","year":"1973","journal-title":"Biochem. Pharmacol."},{"key":"10.1074\/jbc.273.42.27076_bib34","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1523\/JNEUROSCI.06-01-00192.1986","volume":"6","author":"Couraud","year":"1986","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.273.42.27076_bib35","doi-asserted-by":"crossref","first-page":"2836","DOI":"10.1523\/JNEUROSCI.04-11-02836.1984","volume":"4","author":"Gonoi","year":"1984","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.273.42.27076_bib36","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1146\/annurev.ne.10.030187.001321","volume":"10","author":"Strichartz","year":"1987","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1074\/jbc.273.42.27076_bib37","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0169-328X(96)00241-0","volume":"45","author":"Felts","year":"1997","journal-title":"Mol. Brain Res."},{"key":"10.1074\/jbc.273.42.27076_bib38","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1085\/jgp.89.3.459","volume":"89","author":"Garber","year":"1987","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.273.42.27076_bib39","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1085\/jgp.97.3.605","volume":"97","author":"Correa","year":"1991","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.273.42.27076_bib40","first-page":"144","volume":"37","author":"Wang","year":"1990","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.273.42.27076_bib41","doi-asserted-by":"crossref","first-page":"2653","DOI":"10.1073\/pnas.95.5.2653","volume":"95","author":"Wang","year":"1998","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1074\/jbc.273.42.27076_bib42","doi-asserted-by":"crossref","first-page":"15950","DOI":"10.1074\/jbc.271.27.15950","volume":"271","author":"Rogers","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.273.42.27076_bib43","doi-asserted-by":"crossref","first-page":"10161","DOI":"10.1073\/pnas.86.24.10161","volume":"86","author":"Thomsen","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819596405?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819596405?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.273.42.27076","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T23:35:44Z","timestamp":1641166544000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819596405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,10]]},"references-count":43,"journal-issue":{"issue":"42","published-print":{"date-parts":[[1998,10]]}},"alternative-id":["S0021925819596405"],"URL":"https:\/\/doi.org\/10.1074\/jbc.273.42.27076","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1998,10]]}}}