{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T07:34:17Z","timestamp":1790321657827,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"37","license":[{"start":{"date-parts":[[1999,9,1]],"date-time":"1999-09-01T00:00:00Z","timestamp":936144000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,7]],"date-time":"2020-10-07T00:00:00Z","timestamp":1602028800000},"content-version":"vor","delay-in-days":7707,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[1999,9]]},"DOI":"10.1074\/jbc.274.37.26469","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:56:47Z","timestamp":1027695407000},"page":"26469-26476","source":"Crossref","is-referenced-by-count":74,"title":["Calmodulin and Protein Kinase C Increase Ca2+-stimulated Secretion by Modulating Membrane-attached Exocytic Machinery"],"prefix":"10.1016","volume":"274","author":[{"given":"Yu A.","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Duvvuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Schulman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard H.","family":"Scheller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.274.37.26469_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.1996.76.1.1","volume":"76","author":"Calakos","year":"1996","journal-title":"Physiol. Rev."},{"key":"10.1074\/jbc.274.37.26469_bib2","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1038\/375645a0","volume":"375","author":"S\u00fcdhof","year":"1995","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib3","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0896-6273(00)80238-X","volume":"17","author":"Zucker","year":"1996","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib4","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S0959-4388(97)80057-8","volume":"7","author":"Hanson","year":"1997","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1074\/jbc.274.37.26469_bib5","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0092-8674(00)80727-8","volume":"97","author":"Chen","year":"1999","journal-title":"Cell"},{"key":"10.1074\/jbc.274.37.26469_bib6","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0896-6273(93)90238-M","volume":"10","author":"Neher","year":"1993","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib7","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/371603a0","volume":"371","author":"Kamiya","year":"1994","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib8","doi-asserted-by":"crossref","first-page":"27116","DOI":"10.1074\/jbc.271.43.27116","volume":"271","author":"Corradi","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib9","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/0092-8674(92)90310-9","volume":"70","author":"Walent","year":"1992","journal-title":"Cell"},{"key":"10.1074\/jbc.274.37.26469_bib10","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0076-6879(89)68016-0","volume":"168","author":"Martin","year":"1989","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.274.37.26469_bib11","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1083\/jcb.119.1.139","volume":"119","author":"Hay","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.274.37.26469_bib12","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/366572a0","volume":"366","author":"Hay","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib13","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/374173a0","volume":"374","author":"Hay","year":"1995","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib14","doi-asserted-by":"crossref","first-page":"19637","DOI":"10.1074\/jbc.272.32.19637","volume":"272","author":"Ann","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib15","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/347561a0","volume":"347","author":"Bankaitis","year":"1990","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib16","doi-asserted-by":"crossref","first-page":"12593","DOI":"10.1073\/pnas.93.22.12593","volume":"93","author":"Miller","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.274.37.26469_bib17","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1098\/rspb.1982.0064","volume":"216","author":"Burgoyne","year":"1982","journal-title":"Proc. R. Soc. Lond. B Biol. Sci."},{"key":"10.1074\/jbc.274.37.26469_bib18","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0006-291X(05)80138-X","volume":"182","author":"Ganguly","year":"1992","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.274.37.26469_bib19","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/0922-4106(95)90081-0","volume":"291","author":"Verhage","year":"1995","journal-title":"Eur. J. Pharmacol."},{"key":"10.1074\/jbc.274.37.26469_bib20","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/295154a0","volume":"295","author":"Steinhardt","year":"1982","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib21","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0306-4522(85)90183-6","volume":"14","author":"Kenigsberg","year":"1985","journal-title":"Neuroscience"},{"key":"10.1074\/jbc.274.37.26469_bib22","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1083\/jcb.118.6.1501","volume":"118","author":"Birch","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.274.37.26469_bib23","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0896-6273(00)80036-7","volume":"16","author":"Artalejo","year":"1996","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib24","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1038\/25133","volume":"396","author":"Peters","year":"1998","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib25","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1146\/annurev.ph.57.030195.002221","volume":"57","author":"Braun","year":"1995","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.274.37.26469_bib26","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/343647a0","volume":"343","author":"Nichols","year":"1990","journal-title":"Nature"},{"key":"10.1074\/jbc.274.37.26469_bib27","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/0896-6273(95)90315-1","volume":"14","author":"Chapman","year":"1995","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1469-7793.1999.001ad.x","volume":"515","author":"Hilfiker","year":"1999","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.274.37.26469_bib29","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1523\/JNEUROSCI.16-02-00425.1996","volume":"16","author":"Byrne","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.274.37.26469_bib30","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0896-6273(00)80520-6","volume":"21","author":"Betz","year":"1998","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib31","doi-asserted-by":"crossref","first-page":"5729","DOI":"10.1073\/pnas.88.13.5729","volume":"88","author":"Maruyama","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.274.37.26469_bib32","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0896-6273(93)90186-U","volume":"11","author":"Swartz","year":"1993","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib33","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/0896-6273(95)90183-3","volume":"15","author":"Stea","year":"1995","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib34","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/S0896-6273(00)80147-6","volume":"16","author":"Gillis","year":"1996","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib35","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/S0896-6273(00)80603-0","volume":"21","author":"Stevens","year":"1998","journal-title":"Neuron"},{"key":"10.1074\/jbc.274.37.26469_bib36","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1469-7793.1999.169ad.x","volume":"515.1","author":"Yawo","year":"1999","journal-title":"J. Physiol."},{"key":"10.1074\/jbc.274.37.26469_bib37","doi-asserted-by":"crossref","first-page":"14548","DOI":"10.1074\/jbc.271.24.14548","volume":"271","author":"Shimazaki","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib38","doi-asserted-by":"crossref","first-page":"23972","DOI":"10.1016\/S0021-9258(18)35932-5","volume":"267","author":"Nishizaki","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib39","doi-asserted-by":"crossref","first-page":"7265","DOI":"10.1074\/jbc.271.13.7265","volume":"271","author":"Fujita","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib40","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0166-2236(98)01288-0","volume":"22","author":"Chakravarthy","year":"1999","journal-title":"Trends Neurosci."},{"key":"10.1074\/jbc.274.37.26469_bib41","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1085\/jgp.103.3.365","volume":"103","author":"Dolmetsch","year":"1994","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.274.37.26469_bib42","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","volume":"260","author":"Grynkiewicz","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib43","series-title":"Strategies for Protein Purification and Characterization: A Laboratory Course Manual","author":"Marshak","year":"1996"},{"key":"10.1074\/jbc.274.37.26469_bib44","doi-asserted-by":"crossref","first-page":"17579","DOI":"10.1074\/jbc.273.28.17579","volume":"273","author":"Waxham","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib45","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0092-8674(90)90250-I","volume":"62","author":"Kink","year":"1990","journal-title":"Cell"},{"key":"10.1074\/jbc.274.37.26469_bib46","doi-asserted-by":"crossref","first-page":"5510","DOI":"10.1074\/jbc.272.9.5510","volume":"272","author":"Chin","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib47","doi-asserted-by":"crossref","first-page":"30465","DOI":"10.1074\/jbc.271.48.30465","volume":"271","author":"Chin","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib48","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1126\/science.1439804","volume":"258","author":"Creutz","year":"1992","journal-title":"Science"},{"key":"10.1074\/jbc.274.37.26469_bib49","doi-asserted-by":"crossref","first-page":"16219","DOI":"10.1016\/S0021-9258(18)41988-6","volume":"267","author":"Bittner","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib50","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1126\/science.8235626","volume":"262","author":"von R\u00fcden","year":"1993","journal-title":"Science"},{"key":"10.1074\/jbc.274.37.26469_bib51","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1113\/jphysiol.1992.sp019126","volume":"450","author":"Augustine","year":"1992","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.274.37.26469_bib52","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1083\/jcb.130.5.1063","volume":"130","author":"Chamberlain","year":"1995","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.274.37.26469_bib53","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1007\/BF00711564","volume":"13","author":"Bittner","year":"1993","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1074\/jbc.274.37.26469_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0306-4522(89)90327-8","volume":"29","author":"Trifar\u00f3","year":"1989","journal-title":"Neuroscience"},{"key":"10.1074\/jbc.274.37.26469_bib55","doi-asserted-by":"crossref","first-page":"13808","DOI":"10.1021\/bi960853x","volume":"35","author":"Perin","year":"1996","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.274.37.26469_bib56","doi-asserted-by":"crossref","first-page":"20857","DOI":"10.1074\/jbc.272.33.20857","volume":"272","author":"Park","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.274.37.26469_bib57","doi-asserted-by":"crossref","first-page":"31297","DOI":"10.1074\/jbc.273.47.31297","volume":"273","author":"Xu","year":"1998","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819552371?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819552371?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.274.37.26469","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T21:45:40Z","timestamp":1641159940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819552371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9]]},"references-count":57,"journal-issue":{"issue":"37","published-print":{"date-parts":[[1999,9]]}},"alternative-id":["S0021925819552371"],"URL":"https:\/\/doi.org\/10.1074\/jbc.274.37.26469","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[1999,9]]}}}