{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:57:35Z","timestamp":1791338255533,"version":"4.3.1"},"reference-count":58,"publisher":"Elsevier BV","issue":"29","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T00:00:00Z","timestamp":1601856000000},"content-version":"vor","delay-in-days":7401,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2000,7]]},"DOI":"10.1074\/jbc.m000687200","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:04:49Z","timestamp":1027695889000},"page":"21946-21952","source":"Crossref","is-referenced-by-count":183,"title":["GRB2 Links Signaling to Actin Assembly by Enhancing Interaction of Neural Wiskott-Aldrich Syndrome Protein (N-WASp) with Actin-related Protein (ARP2\/3) Complex"],"prefix":"10.1016","volume":"275","author":[{"given":"Marie-France","family":"Carlier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Nioche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Broutin-L'Hermite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajaa","family":"Boujemaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Le Clainche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coumaran","family":"Egile","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Garbay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Ducruix","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Sansonetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Pantaloni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M000687200_bib1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1083\/jcb.146.2.267","volume":"146","author":"Machesky","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M000687200_bib2","doi-asserted-by":"crossref","first-page":"R235","DOI":"10.1016\/S1074-5521(99)80107-0","volume":"6","author":"Carlier","year":"1999","journal-title":"Chem. Biol."},{"key":"10.1074\/jbc.M000687200_bib3","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/44183","volume":"401","author":"Loisel","year":"1999","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib4","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/S0960-9822(98)00015-3","volume":"8","author":"Machesky","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M000687200_bib6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0092-8674(00)80732-1","volume":"97","author":"Rohatgi","year":"1999","journal-title":"Cell"},{"key":"10.1074\/jbc.M000687200_bib9","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1083\/jcb.146.6.1319","volume":"146","author":"Egile","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M000687200_bib10","doi-asserted-by":"crossref","first-page":"R160","DOI":"10.1016\/S0960-9822(99)80102-X","volume":"9","author":"Bi","year":"1999","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M000687200_bib11","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/34208","volume":"391","author":"Miki","year":"1998","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib12","doi-asserted-by":"crossref","first-page":"6932","DOI":"10.1093\/emboj\/17.23.6932","volume":"17","author":"Miki","year":"1998","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M000687200_bib13","doi-asserted-by":"crossref","first-page":"9648","DOI":"10.1073\/pnas.96.17.9648","volume":"96","author":"Linder","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M000687200_bib14","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/0092-8674(94)90528-2","volume":"78","author":"Derry","year":"1994","journal-title":"Cell"},{"key":"10.1074\/jbc.M000687200_bib15","doi-asserted-by":"crossref","first-page":"5326","DOI":"10.1002\/j.1460-2075.1996.tb00917.x","volume":"15","author":"Miki","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M000687200_bib16","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1083\/jcb.136.3.649","volume":"136","author":"Li","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M000687200_bib17","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1083\/jcb.142.5.1325","volume":"142","author":"Bear","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M000687200_bib18","doi-asserted-by":"crossref","first-page":"14671","DOI":"10.1073\/pnas.94.26.14671","volume":"94","author":"Ramesh","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M000687200_bib19","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0960-9822(98)70396-3","volume":"8","author":"Naqvi","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M000687200_bib20","doi-asserted-by":"crossref","first-page":"17103","DOI":"10.1074\/jbc.274.24.17103","volume":"274","author":"Vaduva","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M000687200_bib21","doi-asserted-by":"crossref","first-page":"5725","DOI":"10.1128\/MCB.15.10.5725","volume":"15","author":"Rivero-Lezcano","year":"1995","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M000687200_bib22","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/S0960-9822(02)00642-5","volume":"6","author":"Banin","year":"1996","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M000687200_bib23","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1091\/mbc.8.9.1709","volume":"8","author":"She","year":"1997","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M000687200_bib24","doi-asserted-by":"crossref","first-page":"27605","DOI":"10.1074\/jbc.274.39.27605","volume":"274","author":"Miki","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M000687200_bib25","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0962-8924(98)01411-1","volume":"9","author":"Ramesh","year":"1999","journal-title":"Trends Cell Biol."},{"key":"10.1074\/jbc.M000687200_bib26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1006\/bbrc.1997.8064","volume":"243","author":"Miki","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M000687200_bib27","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0960-9822(02)00423-2","volume":"6","author":"Aspenstr\u00f6m","year":"1996","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M000687200_bib28","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0092-8674(00)81050-8","volume":"84","author":"Symons","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M000687200_bib29","doi-asserted-by":"crossref","first-page":"5615","DOI":"10.1073\/pnas.93.11.5615","volume":"93","author":"Kolluri","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M000687200_bib30","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/20726","volume":"399","author":"Abdul-Manan","year":"1999","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib31","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1038\/35004513","volume":"404","author":"Kim","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib32","doi-asserted-by":"crossref","first-page":"3867","DOI":"10.1073\/pnas.86.10.3867","volume":"86","author":"Bernardini","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M000687200_bib33","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1093\/emboj\/17.10.2767","volume":"17","author":"Suzuki","year":"1998","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M000687200_bib34","doi-asserted-by":"crossref","first-page":"2627","DOI":"10.1172\/JCI118712","volume":"97","author":"Stewart","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M000687200_bib35","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1038\/44860","volume":"401","author":"Frischknecht","year":"1999","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib36","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1126\/science.7716522","volume":"268","author":"Maignan","year":"1995","journal-title":"Science"},{"key":"10.1074\/jbc.M000687200_bib37","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0014-5793(95)00578-W","volume":"369","author":"Chardin","year":"1995","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M000687200_bib38","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/0092-8674(93)90146-H","volume":"73","author":"Buday","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.M000687200_bib39","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/363045a0","volume":"363","author":"Egan","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib40","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/363085a0","volume":"363","author":"Li","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib41","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/363088a0","volume":"363","author":"Gale","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib42","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/363083a0","volume":"363","author":"Rozackis-Adcock","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib43","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0304-4157(99)00005-2","volume":"1422","author":"Buday","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M000687200_bib44","doi-asserted-by":"crossref","first-page":"3464","DOI":"10.1002\/j.1460-2075.1993.tb06021.x","volume":"12","author":"Matuoka","year":"1993","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M000687200_bib45","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1126\/science.272.5270.1935","volume":"272","author":"Wang","year":"1996","journal-title":"Science"},{"key":"10.1074\/jbc.M000687200_bib46","doi-asserted-by":"crossref","first-page":"3791","DOI":"10.1074\/jbc.273.6.3791","volume":"273","author":"Barylko","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M000687200_bib47","doi-asserted-by":"crossref","first-page":"23311","DOI":"10.1074\/jbc.274.33.23311","volume":"274","author":"Gay","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M000687200_bib48","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/0092-8674(93)90544-Z","volume":"75","author":"Pantaloni","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.M000687200_bib49","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/(SICI)1097-0134(199605)25:1<112::AID-PROT9>3.0.CO;2-L","volume":"25","author":"Guilloteau","year":"1999","journal-title":"Proteins Struct. Funct. Genet."},{"key":"10.1074\/jbc.M000687200_bib50","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1038\/nsb1294-898","volume":"1","author":"Goudreau","year":"1994","journal-title":"Struct. Biol."},{"key":"10.1074\/jbc.M000687200_bib51","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1016\/S0969-2126(94)00106-5","volume":"2","author":"Kohda","year":"1994","journal-title":"Structure"},{"key":"10.1074\/jbc.M000687200_bib52","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1096\/fasebj.13.1.31","volume":"13","author":"Cussac","year":"1999","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M000687200_bib53","doi-asserted-by":"crossref","first-page":"3737","DOI":"10.1021\/jm9911074","volume":"42","author":"Liu","year":"1999","journal-title":"J. Med. Chem."},{"key":"10.1074\/jbc.M000687200_bib54","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1365-2958.1995.mmi_18030413.x","volume":"18","author":"Kocks","year":"1995","journal-title":"Mol. Microbiol."},{"key":"10.1074\/jbc.M000687200_bib55","doi-asserted-by":"crossref","first-page":"4011","DOI":"10.1002\/j.1460-2075.1994.tb06717.x","volume":"13","author":"Cussac","year":"1994","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M000687200_bib56","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/356340a0","volume":"356","author":"Clark","year":"1992","journal-title":"Nature"},{"key":"10.1074\/jbc.M000687200_bib57","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1006\/jmbi.1999.2899","volume":"290","author":"Vidal","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M000687200_bib58","doi-asserted-by":"crossref","first-page":"16830","DOI":"10.1021\/bi00051a034","volume":"34","author":"Bretscher","year":"1995","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M000687200_bib5","doi-asserted-by":"crossref","first-page":"3739","DOI":"10.1073\/pnas.96.7.3739","volume":"96","author":"Machesky","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M000687200_bib7","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0960-9822(99)80218-8","volume":"9","author":"Winter","year":"1999","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M000687200_bib8","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/S0960-9822(99)80243-7","volume":"9","author":"Yarar","year":"1999","journal-title":"Curr. Biol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819796203?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819796203?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M000687200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T23:04:37Z","timestamp":1641251077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819796203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":58,"journal-issue":{"issue":"29","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["S0021925819796203"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m000687200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}