{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T06:11:14Z","timestamp":1779343874300,"version":"3.51.4"},"reference-count":53,"publisher":"Elsevier BV","issue":"27","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,11]],"date-time":"2020-10-11T00:00:00Z","timestamp":1602374400000},"content-version":"vor","delay-in-days":7407,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2000,7]]},"DOI":"10.1074\/jbc.m001555200","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T14:55:13Z","timestamp":1027695313000},"page":"20295-20301","source":"Crossref","is-referenced-by-count":94,"title":["Ca2+-free Calmodulin and Calmodulin Damaged byin Vitro Aging Are Selectively Degraded by 26 S Proteasomes without Ubiquitination"],"prefix":"10.1016","volume":"275","author":[{"given":"Edit","family":"Tarcsa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grazyna","family":"Szymanska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stewart","family":"Lecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare M.","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfred L.","family":"Goldberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M001555200_bib1","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1073\/pnas.74.1.54","volume":"74","author":"Etlinger","year":"1977","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M001555200_bib2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev.biochem.67.1.425","volume":"67","author":"Hershko","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M001555200_bib3","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1139\/o94-049","volume":"72","author":"Vogel","year":"1994","journal-title":"Biochem. Cell Biol."},{"key":"10.1074\/jbc.M001555200_bib4","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0022-2836(88)90608-0","volume":"204","author":"Babu","year":"1988","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M001555200_bib5","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1038\/nsb0995-758","volume":"2","author":"Zhang","year":"1995","journal-title":"Nature Struct. Biol."},{"key":"10.1074\/jbc.M001555200_bib6","doi-asserted-by":"crossref","first-page":"4020","DOI":"10.1021\/bi00435a058","volume":"28","author":"Ota","year":"1989","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M001555200_bib7","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/0003-9861(90)90498-N","volume":"279","author":"Ota","year":"1990","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M001555200_bib8","doi-asserted-by":"crossref","first-page":"28516","DOI":"10.1074\/jbc.273.43.28516","volume":"273","author":"Szymanska","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib9","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1006\/bbrc.1997.7105","volume":"237","author":"Ferrington","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M001555200_bib10","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1073\/pnas.78.2.996","volume":"78","author":"Chafouleas","year":"1981","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M001555200_bib11","doi-asserted-by":"crossref","first-page":"3344","DOI":"10.1016\/S0021-9258(19)83626-8","volume":"260","author":"Gronostajski","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib12","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1002\/pro.5560021011","volume":"2","author":"Potter","year":"1993","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.M001555200_bib13","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0021-9258(19)75855-4","volume":"262","author":"Geiger","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib14","doi-asserted-by":"crossref","first-page":"7757","DOI":"10.1073\/pnas.81.24.7757","volume":"81","author":"O'Connor","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M001555200_bib15","doi-asserted-by":"crossref","first-page":"5183","DOI":"10.1021\/bi953063g","volume":"35","author":"Najbauer","year":"1996","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M001555200_bib16","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0021-9258(17)42341-6","volume":"269","author":"Paranandi","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib17","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0021-9258(17)31223-1","volume":"264","author":"Ota","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib18","doi-asserted-by":"crossref","first-page":"12283","DOI":"10.1016\/S0021-9258(18)45348-3","volume":"262","author":"Johnson","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib19","doi-asserted-by":"crossref","first-page":"6323","DOI":"10.1021\/bi00479a001","volume":"29","author":"Stadtman","year":"1990","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M001555200_bib20","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1146\/annurev.bi.65.070196.004101","volume":"65","author":"Coux","year":"1996","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M001555200_bib21","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1146\/annurev.biochem.68.1.1015","volume":"68","author":"Voges","year":"1999","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M001555200_bib22","doi-asserted-by":"crossref","first-page":"4773","DOI":"10.1128\/MCB.16.9.4773","volume":"16","author":"Lee","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M001555200_bib23","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0092-8674(84)90300-3","volume":"37","author":"Ciechanover","year":"1984","journal-title":"Cell"},{"key":"10.1074\/jbc.M001555200_bib24","doi-asserted-by":"crossref","first-page":"227S","DOI":"10.1093\/jn\/129.1.227S","volume":"129 Suppl. 1S","author":"Lecker","year":"1999","journal-title":"J. Nutr."},{"key":"10.1074\/jbc.M001555200_bib25","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/0092-8674(87)90711-2","volume":"48","author":"Finley","year":"1987","journal-title":"Cell"},{"key":"10.1074\/jbc.M001555200_bib26","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/361369a0","volume":"361","author":"Jungmann","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M001555200_bib27","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/360597a0","volume":"360","author":"Murakami","year":"1992","journal-title":"Nature"},{"key":"10.1074\/jbc.M001555200_bib28","doi-asserted-by":"crossref","first-page":"11623","DOI":"10.1074\/jbc.270.19.11623","volume":"270","author":"Jariel-Encontre","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib29","doi-asserted-by":"crossref","first-page":"6716","DOI":"10.1002\/j.1460-2075.1996.tb01061.x","volume":"15","author":"Krappmann","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M001555200_bib30","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1096\/fasebj.11.13.9367341","volume":"11","author":"Pickart","year":"1997","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M001555200_bib31","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1093\/emboj\/19.1.94","volume":"19","author":"Thrower","year":"2000","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M001555200_bib32","doi-asserted-by":"crossref","first-page":"3363","DOI":"10.1074\/jbc.274.6.3363","volume":"274","author":"Kisselev","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib33","series-title":"Molecular Cloning, A Laboratory Manual","author":"Sambrook","year":"1989"},{"key":"10.1074\/jbc.M001555200_bib34","doi-asserted-by":"crossref","first-page":"4704","DOI":"10.1016\/S0021-9258(18)89127-X","volume":"260","author":"Putkey","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib35","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1006\/abio.1997.2319","volume":"252","author":"Szymanska","year":"1997","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M001555200_bib36","doi-asserted-by":"crossref","first-page":"21368","DOI":"10.1016\/S0021-9258(17)45370-1","volume":"265","author":"Desrosiers","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib37","doi-asserted-by":"crossref","first-page":"25216","DOI":"10.1074\/jbc.273.39.25216","volume":"273","author":"Solomon","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib38","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/0006-291X(85)91050-2","volume":"128","author":"Hershko","year":"1985","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M001555200_bib39","doi-asserted-by":"crossref","first-page":"13437","DOI":"10.1074\/jbc.272.20.13437","volume":"272","author":"Craiu","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib40","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S0962-8924(98)01346-4","volume":"8","author":"Lee","year":"1998","journal-title":"Trends Cell Biol."},{"key":"10.1074\/jbc.M001555200_bib41","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1073\/pnas.84.7.1829","volume":"84","author":"Hershko","year":"1987","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M001555200_bib42","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1515\/bchm3.1988.369.2.1317","volume":"369","author":"Ziegenhagen","year":"1988","journal-title":"Biol. Chem. Hoppe-Seyler"},{"key":"10.1074\/jbc.M001555200_bib43","doi-asserted-by":"crossref","first-page":"8172","DOI":"10.1074\/jbc.270.14.8172","volume":"270","author":"Johnston","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib44","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S1097-2765(00)80435-9","volume":"5","author":"Sheaff","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M001555200_bib45","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1038\/12043","volume":"1","author":"Braun","year":"1999","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M001555200_bib46","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1111\/j.1432-1033.1992.tb19822.x","volume":"203","author":"Goldberg","year":"1992","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M001555200_bib47","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0092-8674(00)80428-6","volume":"91","author":"Gottesman","year":"1997","journal-title":"Cell"},{"key":"10.1074\/jbc.M001555200_bib48","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1083\/jcb.96.6.1580","volume":"96","author":"Tanaka","year":"1983","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M001555200_bib49","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0092-8674(87)90149-8","volume":"51","author":"Ball","year":"1987","journal-title":"Cell"},{"key":"10.1074\/jbc.M001555200_bib50","doi-asserted-by":"crossref","first-page":"2562","DOI":"10.1016\/S0021-9258(18)61542-X","volume":"262","author":"Gregori","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M001555200_bib51","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1046\/j.1432-1327.1998.2550422.x","volume":"255","author":"Laub","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M001555200_bib52","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1126\/science.2538923","volume":"243","author":"Chau","year":"1989","journal-title":"Science"},{"key":"10.1074\/jbc.M001555200_bib53","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0167-4889(97)00017-7","volume":"1357","author":"Laub","year":"1997","journal-title":"Biochem. Biophys. Acta"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819798342?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819798342?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M001555200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T23:11:32Z","timestamp":1641251492000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819798342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":53,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["S0021925819798342"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m001555200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}