{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T05:42:28Z","timestamp":1789882948749,"version":"4.0.1"},"reference-count":39,"publisher":"Elsevier BV","issue":"26","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":7062,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2001,6]]},"DOI":"10.1074\/jbc.m007856200","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T15:16:07Z","timestamp":1027696567000},"page":"23480-23485","source":"Crossref","is-referenced-by-count":52,"title":["Discovery of a Novel Enzyme, Isonitrile Hydratase, Involved in Nitrogen-Carbon Triple Bond Cleavage"],"prefix":"10.1016","volume":"276","author":[{"given":"Masahiko","family":"Goda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiteru","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sakayu","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michihiko","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M007856200_bib1","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/nbt0898-733","volume":"16","author":"Kobayashi","year":"1998","journal-title":"Nat. Biotechnol."},{"key":"10.1074\/jbc.M007856200_bib2","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1271\/bbb.60.1391","volume":"60","author":"Yamada","year":"1996","journal-title":"Biosci. Biotech. Biochem."},{"key":"10.1074\/jbc.M007856200_bib3","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/0167-7799(92)90283-2","volume":"10","author":"Kobayashi","year":"1992","journal-title":"Trends Biotechnol."},{"key":"10.1074\/jbc.M007856200_bib4","doi-asserted-by":"crossref","first-page":"10572","DOI":"10.1073\/pnas.93.20.10572","volume":"93","author":"Komeda","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M007856200_bib5","doi-asserted-by":"crossref","first-page":"20746","DOI":"10.1016\/S0021-9258(19)36749-3","volume":"267","author":"Kobayashi","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M007856200_bib6","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1073\/pnas.90.1.247","volume":"90","author":"Kobayashi","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M007856200_bib7","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1574-6968.1994.tb07036.x","volume":"120","author":"Kobayashi","year":"1994","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1074\/jbc.M007856200_bib8","doi-asserted-by":"crossref","first-page":"4267","DOI":"10.1073\/pnas.93.9.4267","volume":"93","author":"Komeda","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M007856200_bib9","doi-asserted-by":"crossref","first-page":"15796","DOI":"10.1074\/jbc.271.26.15796","volume":"271","author":"Komeda","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M007856200_bib10","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1073\/pnas.92.3.714","volume":"92","author":"Kobayashi","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M007856200_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1432-1327.1999.00186.x","volume":"261","author":"Kobayashi","year":"1999","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M007856200_bib12","doi-asserted-by":"crossref","first-page":"11986","DOI":"10.1073\/pnas.94.22.11986","volume":"94","author":"Kobayashi","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M007856200_bib13","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0014-5793(98)01406-9","volume":"439","author":"Kobayashi","year":"1998","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M007856200_bib14","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1432-1033.1993.tb18250.x","volume":"217","author":"Kobayashi","year":"1993","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M007856200_bib15","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1039\/np9880500229","volume":"5","author":"Edenborough","year":"1988","journal-title":"Natl. Prod. Rep."},{"key":"10.1074\/jbc.M007856200_bib16","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1021\/ar00022a001","volume":"25","author":"Scheuer","year":"1992","journal-title":"Acc. Chem. Res."},{"key":"10.1074\/jbc.M007856200_bib17","first-page":"567","volume":"12","author":"Hagedorn","year":"1957","journal-title":"Pharmazie"},{"key":"10.1074\/jbc.M007856200_bib18","doi-asserted-by":"crossref","first-page":"4259","DOI":"10.1016\/0040-4020(73)80267-4","volume":"29","author":"Cafieri","year":"1973","journal-title":"Tetrahedron"},{"key":"10.1074\/jbc.M007856200_bib19","doi-asserted-by":"crossref","first-page":"4763","DOI":"10.1021\/ja00849a053","volume":"97","author":"Burreson","year":"1975","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M007856200_bib20","doi-asserted-by":"crossref","first-page":"1c","DOI":"10.1042\/bj1020001C","volume":"102","author":"Kelly","year":"1967","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M007856200_bib21","doi-asserted-by":"crossref","first-page":"6260","DOI":"10.1021\/bi00295a034","volume":"22","author":"Rubinson","year":"1983","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M007856200_bib22","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M007856200_bib23","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1074\/jbc.M007856200_bib24","first-page":"79","volume":"43","author":"Katoh","year":"1983","journal-title":"Rept. Natl. Food. Res. Inst."},{"key":"10.1074\/jbc.M007856200_bib25","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1111\/j.1574-6968.1984.tb01388.x","volume":"25","author":"Tamaoka","year":"1984","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1074\/jbc.M007856200_bib26","first-page":"3169","volume":"48","author":"Katayama-Fujimura","year":"1984","journal-title":"Agric. Biol. Chem."},{"key":"10.1074\/jbc.M007856200_bib27","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/j.1432-1033.1987.tb10692.x","volume":"162","author":"Nagasawa","year":"1987","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M007856200_bib28","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1128\/jb.173.8.2465-2472.1991","volume":"173","author":"Nishiyama","year":"1991","journal-title":"J. Bacteriol."},{"key":"10.1074\/jbc.M007856200_bib29","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/S0006-291X(86)80320-5","volume":"139","author":"Nagasawa","year":"1986","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M007856200_bib30","doi-asserted-by":"crossref","first-page":"5848","DOI":"10.1021\/ja00253a046","volume":"109","author":"Sugiura","year":"1987","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M007856200_bib31","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1073\/pnas.94.1.36","volume":"94","author":"Komeda","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M007856200_bib32","doi-asserted-by":"crossref","first-page":"9000","DOI":"10.1021\/bi00152a042","volume":"31","author":"Kobayashi","year":"1992","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M007856200_bib33","doi-asserted-by":"crossref","first-page":"4807","DOI":"10.1128\/jb.172.9.4807-4815.1990","volume":"172","author":"Kobayashi","year":"1990","journal-title":"J. Bacteriol."},{"key":"10.1074\/jbc.M007856200_bib34","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S1367-5931(99)00058-7","volume":"4","author":"Kobayashi","year":"2000","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1074\/jbc.M007856200_bib35","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1432-1033.1989.tb14837.x","volume":"182","author":"Kobayashi","year":"1989","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M007856200_bib36","doi-asserted-by":"crossref","first-page":"2447","DOI":"10.1021\/ja00320a044","volume":"106","author":"Hagadone","year":"1984","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M007856200_bib37","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1515\/znb-1965-0209","volume":"20B","author":"Achenbach","year":"1965","journal-title":"Z. Naturforsch."},{"key":"10.1074\/jbc.M007856200_bib38","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1002\/cber.19721050307","volume":"105","author":"Achenbach","year":"1972","journal-title":"Chem. Ber."},{"key":"10.1074\/jbc.M007856200_bib39","first-page":"536","volume":"27","author":"Pfeifer","year":"1972","journal-title":"Pharmazie"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820783377?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820783377?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M007856200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T17:55:38Z","timestamp":1641405338000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820783377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6]]},"references-count":39,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2001,6]]}},"alternative-id":["S0021925820783377"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m007856200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2001,6]]}}}