{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T22:21:55Z","timestamp":1790979715278,"version":"4.1.0"},"reference-count":83,"publisher":"Elsevier BV","issue":"47","license":[{"start":{"date-parts":[[2009,11,1]],"date-time":"2009-11-01T00:00:00Z","timestamp":1257033600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T00:00:00Z","timestamp":1598659200000},"content-version":"vor","delay-in-days":3954,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2009,11]]},"DOI":"10.1074\/jbc.m109.040907","type":"journal-article","created":{"date-parts":[[2009,9,17]],"date-time":"2009-09-17T00:14:25Z","timestamp":1253146465000},"page":"32444-32453","source":"Crossref","is-referenced-by-count":84,"title":["Crystal Structure of a Mucus-binding Protein Repeat Reveals an Unexpected Functional Immunoglobulin Binding Activity"],"prefix":"10.1016","volume":"284","author":[{"given":"Donald A.","family":"MacKenzie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise E.","family":"Tailford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M.","family":"Hemmings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Juge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M109.040907_bib1","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1126\/science.1155725","volume":"320","author":"Ley","year":"2008","journal-title":"Science"},{"key":"10.1074\/jbc.M109.040907_bib2","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1126\/science.1124234","volume":"312","author":"Gill","year":"2006","journal-title":"Science"},{"key":"10.1074\/jbc.M109.040907_bib3","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/mi.2008.5","volume":"1","author":"Linden","year":"2008","journal-title":"Nature Mucosal Immunol."},{"key":"10.1074\/jbc.M109.040907_bib4","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1126\/science.1058709","volume":"292","author":"Hooper","year":"2001","journal-title":"Science"},{"key":"10.1074\/jbc.M109.040907_bib5","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1126\/science.1104816","volume":"307","author":"B\u00e4ckhed","year":"2005","journal-title":"Science"},{"key":"10.1074\/jbc.M109.040907_bib6","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1126\/science.1109051","volume":"307","author":"Sonnenburg","year":"2005","journal-title":"Science"},{"key":"10.1074\/jbc.M109.040907_bib7","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.chom.2008.09.007","volume":"4","author":"Martens","year":"2008","journal-title":"Cell Host Microbe"},{"key":"10.1074\/jbc.M109.040907_bib8","doi-asserted-by":"crossref","first-page":"4985","DOI":"10.1128\/AEM.00753-08","volume":"74","author":"Walter","year":"2008","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib9","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1007\/978-0-387-74087-4_17","volume":"606","author":"Gill","year":"2008","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1074\/jbc.M109.040907_bib10","doi-asserted-by":"crossref","first-page":"803S","DOI":"10.1093\/jn\/137.3.803S","volume":"137","author":"de Vrese","year":"2007","journal-title":"J. Nutr."},{"key":"10.1074\/jbc.M109.040907_bib11","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1128\/MMBR.00017-08","volume":"72","author":"Lebeer","year":"2008","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1074\/jbc.M109.040907_bib12","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1574-6968.1998.tb13226.x","volume":"167","author":"Kirjavainen","year":"1998","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1074\/jbc.M109.040907_bib13","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0168-1605(00)00440-2","volume":"64","author":"Ouwehand","year":"2001","journal-title":"Int. J. Food. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib14","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1099\/jmm.0.05009-0","volume":"52","author":"Lee","year":"2003","journal-title":"J. Med. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib15","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1111\/j.1472-765X.2006.01844.x","volume":"42","author":"Ma","year":"2006","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib16","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1099\/mic.0.28522-0","volume":"152","author":"Vesterlund","year":"2006","journal-title":"Microbiology"},{"key":"10.1074\/jbc.M109.040907_bib17","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/s00284-007-0144-8","volume":"55","author":"Collado","year":"2007","journal-title":"Curr. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib18","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1111\/j.1365-2672.2007.03636.x","volume":"104","author":"Li","year":"2008","journal-title":"J. Appl. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib19","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00203-008-0436-9","volume":"191","author":"Mu\u00f1oz-Provencio","year":"2009","journal-title":"Arch. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib20","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1086\/420823","volume":"38","author":"Macfarlane","year":"2004","journal-title":"Clin. Infect. Dis."},{"key":"10.1074\/jbc.M109.040907_bib21","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1111\/j.1365-2672.2007.03287.x","volume":"102","author":"Macfarlane","year":"2007","journal-title":"J. Appl. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib22","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1128\/AEM.68.5.2330-2336.2002","volume":"68","author":"Rojas","year":"2002","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib23","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1099\/00221287-148-2-433","volume":"148","author":"Roos","year":"2002","journal-title":"Microbiology"},{"key":"10.1074\/jbc.M109.040907_bib24","doi-asserted-by":"crossref","first-page":"2160","DOI":"10.1128\/IAI.72.4.2160-2169.2004","volume":"72","author":"Granato","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1074\/jbc.M109.040907_bib25","doi-asserted-by":"crossref","first-page":"8344","DOI":"10.1128\/AEM.71.12.8344-8351.2005","volume":"71","author":"Buck","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib26","doi-asserted-by":"crossref","first-page":"6128","DOI":"10.1128\/JB.187.17.6128-6136.2005","volume":"187","author":"Pretzer","year":"2005","journal-title":"J. Bacteriol."},{"key":"10.1074\/jbc.M109.040907_bib27","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1271\/bbb.50688","volume":"70","author":"Miyoshi","year":"2006","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1074\/jbc.M109.040907_bib28","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1472-765X.2006.02031.x","volume":"44","author":"Sun","year":"2007","journal-title":"Lett. Appl. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib29","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1111\/j.1365-2672.2006.03086.x","volume":"102","author":"Tallon","year":"2007","journal-title":"J. Appl. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib30","author":"Mac\u00edas-Rodr\u00edguez","year":"2009","journal-title":"J. Appl. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2006.00122.x","volume":"256","author":"Desvaux","year":"2006","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1074\/jbc.M109.040907_bib32","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1099\/mic.0.28415-0","volume":"152","author":"Boekhorst","year":"2006","journal-title":"Microbiology"},{"key":"10.1074\/jbc.M109.040907_bib33","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/prot.21205","volume":"66","author":"Bumbaca","year":"2007","journal-title":"Proteins"},{"key":"10.1074\/jbc.M109.040907_bib34","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/0003-2697(90)90396-Q","volume":"191","author":"van Stokkum","year":"1990","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M109.040907_bib35","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1107\/S0907444999000839","volume":"55","author":"Terwilliger","year":"1999","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1074\/jbc.M109.040907_bib36","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S0076-6879(03)74002-6","volume":"374","author":"Terwilliger","year":"2003","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M109.040907_bib37","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/8263","volume":"6","author":"Perrakis","year":"1999","journal-title":"Nat. Struct. Biol."},{"key":"10.1074\/jbc.M109.040907_bib38","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1107\/S0907444904019158","volume":"60","author":"Emsley","year":"2004","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1074\/jbc.M109.040907_bib39","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1107\/S0907444902016657","volume":"58","author":"Adams","year":"2002","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1074\/jbc.M109.040907_bib40","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1107\/S0907444996012255","volume":"53","author":"Murshudov","year":"1997","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1074\/jbc.M109.040907_bib41","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.1093\/bioinformatics\/btn507","volume":"24","author":"Holm","year":"2008","journal-title":"Bioinformatics"},{"key":"10.1074\/jbc.M109.040907_bib42","doi-asserted-by":"crossref","first-page":"W299","DOI":"10.1093\/nar\/gki370","volume":"33","author":"Landau","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M109.040907_bib43","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1006\/jmbi.2000.4042","volume":"302","author":"Notredame","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.040907_bib44","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/bioinformatics\/15.4.305","volume":"15","author":"Gouet","year":"1999","journal-title":"Bioinformatics"},{"key":"10.1074\/jbc.M109.040907_bib45","doi-asserted-by":"crossref","first-page":"D281","DOI":"10.1093\/nar\/gkm960","volume":"36","author":"Finn","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M109.040907_bib46","first-page":"536","volume":"247","author":"Murzin","year":"1995","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.040907_bib47","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1107\/S0907444999007374","volume":"55","author":"Harding","year":"1999","journal-title":"Acta Crystallogr. Sect. D"},{"key":"10.1074\/jbc.M109.040907_bib48","doi-asserted-by":"crossref","first-page":"12820","DOI":"10.1016\/S0021-9258(18)42349-6","volume":"267","author":"Kastern","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M109.040907_bib49","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.4049\/jimmunol.140.4.1194","volume":"140","author":"Bj\u00f6rck","year":"1988","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M109.040907_bib50","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1042\/bj3400193","volume":"340","author":"Beckingham","year":"1999","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M109.040907_bib51","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1006\/jmbi.1994.1691","volume":"243","author":"Derrick","year":"1994","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.040907_bib52","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0969-2126(01)00157-5","volume":"3","author":"Sauer-Eriksson","year":"1995","journal-title":"Structure"},{"key":"10.1074\/jbc.M109.040907_bib53","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1042\/bst0310716","volume":"31","author":"Housden","year":"2003","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M109.040907_bib54","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S0969-2126(01)00630-X","volume":"9","author":"Graille","year":"2001","journal-title":"Structure"},{"key":"10.1074\/jbc.M109.040907_bib55","doi-asserted-by":"crossref","first-page":"47500","DOI":"10.1074\/jbc.M206105200","volume":"277","author":"Graille","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M109.040907_bib56","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.str.2007.06.015","volume":"15","author":"Krishnan","year":"2007","journal-title":"Structure"},{"key":"10.1074\/jbc.M109.040907_bib57","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1016\/j.micinf.2006.03.011","volume":"8","author":"Schwarz-Linek","year":"2006","journal-title":"Microbes Infect."},{"key":"10.1074\/jbc.M109.040907_bib58","doi-asserted-by":"crossref","first-page":"14011","DOI":"10.1021\/bi00251a008","volume":"33","author":"Wikstr\u00f6m","year":"1994","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M109.040907_bib59","doi-asserted-by":"crossref","first-page":"822","DOI":"10.4049\/jimmunol.97.6.822","volume":"97","author":"Forsgren","year":"1966","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M109.040907_bib60","doi-asserted-by":"crossref","first-page":"969","DOI":"10.4049\/jimmunol.133.2.969","volume":"133","author":"Bj\u00f6rck","year":"1984","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M109.040907_bib61","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/j.1432-1033.1977.tb11324.x","volume":"73","author":"Sjodahl","year":"1977","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M109.040907_bib62","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1002\/j.1460-2075.1986.tb04398.x","volume":"5","author":"Guss","year":"1986","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M109.040907_bib63","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1111\/j.1365-2958.1994.tb01079.x","volume":"12","author":"Murphy","year":"1994","journal-title":"Mol. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib64","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0065-2776(08)60722-1","volume":"32","author":"Langone","year":"1982","journal-title":"Adv. Immunol."},{"key":"10.1074\/jbc.M109.040907_bib65","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/0968-0004(93)90021-E","volume":"18","author":"Goward","year":"1993","journal-title":"Trends Biochem. Sci."},{"key":"10.1074\/jbc.M109.040907_bib66","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1016\/S0021-9258(18)45867-X","volume":"267","author":"Nilson","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M109.040907_bib67","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1006\/jmbi.1997.1090","volume":"270","author":"Enokizono","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.040907_bib68","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1006\/jmbi.1995.0364","volume":"250","author":"Wikstr\u00f6m","year":"1995","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.040907_bib69","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1042\/bj3530395","volume":"353","author":"Beckingham","year":"2001","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M109.040907_bib70","doi-asserted-by":"crossref","first-page":"2445","DOI":"10.1021\/bi034873s","volume":"43","author":"Svensson","year":"2004","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M109.040907_bib71","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/j.0105-2896.2005.00290.x","volume":"206","author":"Woof","year":"2005","journal-title":"Immunol. Rev."},{"key":"10.1074\/jbc.M109.040907_bib72","first-page":"12","volume":"74","author":"Kazeeva","year":"2009","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M109.040907_bib73","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1016\/j.molimm.2009.02.024","volume":"46","author":"Leo","year":"2009","journal-title":"Mol. Immunol."},{"key":"10.1074\/jbc.M109.040907_bib74","doi-asserted-by":"crossref","first-page":"8197","DOI":"10.1074\/jbc.M009396200","volume":"276","author":"Pleass","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M109.040907_bib75","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.str.2005.10.012","volume":"14","author":"Agniswamy","year":"2006","journal-title":"Structure"},{"key":"10.1074\/jbc.M109.040907_bib76","doi-asserted-by":"crossref","first-page":"2926","DOI":"10.4049\/jimmunol.174.5.2926","volume":"174","author":"Langley","year":"2005","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M109.040907_bib77","first-page":"43","volume":"2","author":"Reuter","year":"2001","journal-title":"Curr. Issues Intest. Microbiol."},{"key":"10.1074\/jbc.M109.040907_bib78","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1073\/pnas.0337704100","volume":"100","author":"Kleerebezem","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M109.040907_bib79","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1101\/gr.169701","volume":"11","author":"Bolotin","year":"2001","journal-title":"Genome Res."},{"key":"10.1074\/jbc.M109.040907_bib80","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.chom.2007.09.013","volume":"2","author":"Peterson","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1074\/jbc.M109.040907_bib81","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/mi.2007.6","volume":"1","author":"Macpherson","year":"2008","journal-title":"Mucosal Immunol."},{"key":"10.1074\/jbc.M109.040907_bib82","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1093\/bioinformatics\/btp033","volume":"25","author":"Waterhouse","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1074\/jbc.M109.040907_bib83","doi-asserted-by":"crossref","first-page":"W375","DOI":"10.1093\/nar\/gkm216","volume":"35","author":"Davis","year":"2007","journal-title":"Nucleic Acids Res."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820378364?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820378364?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M109.040907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,16]],"date-time":"2024-03-16T16:14:30Z","timestamp":1710605670000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820378364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,11]]},"references-count":83,"journal-issue":{"issue":"47","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["S0021925820378364"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m109.040907","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2009,11]]}}}