{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:19:07Z","timestamp":1790864347917,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"39","license":[{"start":{"date-parts":[[2010,9,1]],"date-time":"2010-09-01T00:00:00Z","timestamp":1283299200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,25]],"date-time":"2020-10-25T00:00:00Z","timestamp":1603584000000},"content-version":"vor","delay-in-days":3707,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2010,9]]},"DOI":"10.1074\/jbc.m109.094086","type":"journal-article","created":{"date-parts":[[2010,7,13]],"date-time":"2010-07-13T03:13:07Z","timestamp":1278990787000},"page":"30103-30114","source":"Crossref","is-referenced-by-count":40,"title":["Physical Basis behind Achondroplasia, the Most Common Form of Human Dwarfism"],"prefix":"10.1016","volume":"285","author":[{"given":"Lijuan","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Horton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalina","family":"Hristova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M109.094086_bib1","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0092-8674(02)00966-2","volume":"110","author":"Schlessinger","year":"2002","journal-title":"Cell"},{"key":"10.1074\/jbc.M109.094086_bib2","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.cytogfr.2005.01.001","volume":"16","author":"Eswarakumar","year":"2005","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1074\/jbc.M109.094086_bib3","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1126\/science.1105396","volume":"306","author":"Schlessinger","year":"2004","journal-title":"Science"},{"key":"10.1074\/jbc.M109.094086_bib4","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/ng0496-390","volume":"12","author":"Colvin","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M109.094086_bib5","first-page":"23","volume":"21","author":"Vajo","year":"2000","journal-title":"Endocr. Rev."},{"key":"10.1074\/jbc.M109.094086_bib6","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/S0140-6736(07)61090-3","volume":"370","author":"Horton","year":"2007","journal-title":"Lancet"},{"key":"10.1074\/jbc.M109.094086_bib7","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/sj.ejhg.5200883","volume":"10","author":"van Rhijn","year":"2002","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1074\/jbc.M109.094086_bib8","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0092-8674(94)90302-6","volume":"78","author":"Shiang","year":"1994","journal-title":"Cell"},{"key":"10.1074\/jbc.M109.094086_bib9","doi-asserted-by":"crossref","first-page":"701","DOI":"10.2106\/00004623-197052040-00004","volume":"52","author":"Ponseti","year":"1970","journal-title":"J. Bone Jt. Surg. Am."},{"key":"10.1074\/jbc.M109.094086_bib10","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1128\/MCB.20.2.516-522.2000","volume":"20","author":"Monsonego-Ornan","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M109.094086_bib11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0014-5793(02)03255-6","volume":"528","author":"Monsonego-Ornan","year":"2002","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M109.094086_bib12","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1073\/pnas.2237184100","volume":"101","author":"Cho","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M109.094086_bib13","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/j.1460-2075.1996.tb00384.x","volume":"15","author":"Webster","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M109.094086_bib14","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1038\/sj.onc.1200983","volume":"14","author":"Li","year":"1997","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M109.094086_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s00774-008-0009-7","volume":"27","author":"Harada","year":"2009","journal-title":"J. Bone Miner. Metab."},{"key":"10.1074\/jbc.M109.094086_bib16","doi-asserted-by":"crossref","first-page":"3078","DOI":"10.1111\/j.1742-4658.2007.05835.x","volume":"274","author":"Bonaventure","year":"2007","journal-title":"FEBS J."},{"key":"10.1074\/jbc.M109.094086_bib17","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/S0168-9525(97)01131-1","volume":"13","author":"Webster","year":"1997","journal-title":"Trends Genet."},{"key":"10.1074\/jbc.M109.094086_bib18","doi-asserted-by":"crossref","first-page":"5551","DOI":"10.1021\/bi060113g","volume":"45","author":"You","year":"2006","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M109.094086_bib19","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.jmb.2005.11.077","volume":"356","author":"Li","year":"2006","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.094086_bib20","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.jmb.2008.10.036","volume":"384","author":"He","year":"2008","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.094086_bib21","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1002\/(SICI)1521-1878(200002)22:2<108::AID-BIES2>3.0.CO;2-M","volume":"22","author":"Ornitz","year":"2000","journal-title":"BioEssays"},{"key":"10.1074\/jbc.M109.094086_bib22","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1042\/BST0340442","volume":"34","author":"Harmer","year":"2006","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M109.094086_bib23","doi-asserted-by":"crossref","first-page":"35250","DOI":"10.1074\/jbc.273.52.35250","volume":"273","author":"Raffioni","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M109.094086_bib24","doi-asserted-by":"crossref","first-page":"3589","DOI":"10.1091\/mbc.11.10.3589","volume":"11","author":"Bell","year":"2000","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M109.094086_bib25","doi-asserted-by":"crossref","first-page":"6241","DOI":"10.1021\/bi060609y","volume":"45","author":"Li","year":"2006","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M109.094086_bib26","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/(SICI)1097-0134(199611)26:3<257::AID-PROT2>3.0.CO;2-B","volume":"26","author":"Adams","year":"1996","journal-title":"Proteins"},{"key":"10.1074\/jbc.M109.094086_bib27","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/nsb0295-154","volume":"2","author":"Adams","year":"1995","journal-title":"Nat. Struct. Biol."},{"key":"10.1074\/jbc.M109.094086_bib28","series-title":"Membrane Protein Assembly","first-page":"251","author":"Adams","year":"1997"},{"key":"10.1074\/jbc.M109.094086_bib29","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1126\/science.1082024","volume":"300","author":"Schlessinger","year":"2003","journal-title":"Science"},{"key":"10.1074\/jbc.M109.094086_bib30","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1073\/pnas.0307287101","volume":"101","author":"Olsen","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M109.094086_bib31","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1006\/jmbi.2001.4923","volume":"311","author":"Moriki","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M109.094086_bib32","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1091\/mbc.01-08-0411","volume":"13","author":"Yu","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M109.094086_bib33","doi-asserted-by":"crossref","first-page":"249","DOI":"10.4161\/cam.4.2.10725","volume":"4","author":"Li","year":"2010","journal-title":"Cell Adhes. Migrat."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819890476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819890476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M109.094086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T03:25:40Z","timestamp":1641266740000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819890476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,9]]},"references-count":33,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["S0021925819890476"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m109.094086","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2010,9]]}}}