{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:10:36Z","timestamp":1790878236199,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"49","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T00:00:00Z","timestamp":1600041600000},"content-version":"vor","delay-in-days":3575,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1074\/jbc.m110.160218","type":"journal-article","created":{"date-parts":[[2010,9,24]],"date-time":"2010-09-24T00:59:36Z","timestamp":1285289976000},"page":"38183-38193","source":"Crossref","is-referenced-by-count":62,"title":["Hsp70 and Hsp40 Functionally Interact with Soluble Mutant Huntingtin Oligomers in a Classic ATP-dependent Reaction Cycle"],"prefix":"10.1016","volume":"285","author":[{"given":"Gregor P.","family":"Lotz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin","family":"Legleiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Aron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily J.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-Yi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheping","family":"Ng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Glabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie M.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Muchowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M110.160218_bib1","doi-asserted-by":"crossref","first-page":"21647","DOI":"10.1074\/jbc.M109.016923","volume":"284","author":"Legleiter","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib2","doi-asserted-by":"crossref","first-page":"14777","DOI":"10.1074\/jbc.M109.093708","volume":"285","author":"Legleiter","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib3","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0092-8674(00)80513-9","volume":"90","author":"Davies","year":"1997","journal-title":"Cell"},{"key":"10.1074\/jbc.M110.160218_bib4","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0092-8674(00)80514-0","volume":"90","author":"Scherzinger","year":"1997","journal-title":"Cell"},{"key":"10.1074\/jbc.M110.160218_bib5","doi-asserted-by":"crossref","first-page":"41032","DOI":"10.1074\/jbc.M205809200","volume":"277","author":"Poirier","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib6","doi-asserted-by":"crossref","first-page":"34717","DOI":"10.1074\/jbc.M209852200","volume":"278","author":"Tanaka","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib7","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/nsmb860","volume":"11","author":"Wacker","year":"2004","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1074\/jbc.M110.160218_bib8","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/nature06022","volume":"448","author":"Bennett","year":"2007","journal-title":"Nature"},{"key":"10.1074\/jbc.M110.160218_bib9","doi-asserted-by":"crossref","first-page":"4398","DOI":"10.1074\/jbc.M806269200","volume":"284","author":"Mitra","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib10","doi-asserted-by":"crossref","first-page":"3675","DOI":"10.1523\/JNEUROSCI.5673-09.2010","volume":"30","author":"Ortega","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M110.160218_bib11","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/nature02998","volume":"431","author":"Arrasate","year":"2004","journal-title":"Nature"},{"key":"10.1074\/jbc.M110.160218_bib12","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1126\/science.1079469","volume":"300","author":"Kayed","year":"2003","journal-title":"Science"},{"key":"10.1074\/jbc.M110.160218_bib13","doi-asserted-by":"crossref","first-page":"29639","DOI":"10.1074\/jbc.R800016200","volume":"283","author":"Glabe","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/nrn1587","volume":"6","author":"Muchowski","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1074\/jbc.M110.160218_bib15","doi-asserted-by":"crossref","first-page":"7841","DOI":"10.1073\/pnas.140202897","volume":"97","author":"Muchowski","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.160218_bib16","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/70532","volume":"23","author":"Warrick","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M110.160218_bib17","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1093\/hmg\/9.13.2009","volume":"9","author":"Jana","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M110.160218_bib18","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1093\/hmg\/10.14.1511","volume":"10","author":"Cummings","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M110.160218_bib19","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1523\/JNEUROSCI.23-06-02203.2003","volume":"23","author":"Adachi","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M110.160218_bib20","doi-asserted-by":"crossref","first-page":"9104","DOI":"10.1523\/JNEUROSCI.2250-09.2009","volume":"29","author":"Wacker","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M110.160218_bib21","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1042\/BST0320617","volume":"32","author":"Erbse","year":"2004","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M110.160218_bib22","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1038\/nrm1492","volume":"5","author":"Young","year":"2004","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1074\/jbc.M110.160218_bib23","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.molcel.2004.06.029","volume":"15","author":"Schaffar","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M110.160218_bib24","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.molcel.2006.08.017","volume":"23","author":"Behrends","year":"2006","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M110.160218_bib25","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1083\/jcb.99.2.723","volume":"99","author":"Schlossman","year":"1984","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110.160218_bib26","doi-asserted-by":"crossref","first-page":"19617","DOI":"10.1074\/jbc.271.32.19617","volume":"271","author":"Minami","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib27","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.jcis.2004.05.009","volume":"278","author":"Legleiter","year":"2004","journal-title":"J. Colloid Interface Sci."},{"key":"10.1074\/jbc.M110.160218_bib28","doi-asserted-by":"crossref","first-page":"17228","DOI":"10.1074\/jbc.M212761200","volume":"278","author":"Lotz","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib29","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1242\/jcs.015610","volume":"121","author":"Lotz","year":"2008","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M110.160218_bib30","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0003-2697(84)90782-6","volume":"138","author":"Wessel","year":"1984","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M110.160218_bib31","doi-asserted-by":"crossref","first-page":"5950","DOI":"10.1073\/pnas.2628045100","volume":"100","author":"Apostol","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.160218_bib32","doi-asserted-by":"crossref","first-page":"33283","DOI":"10.1074\/jbc.272.52.33283","volume":"272","author":"Michels","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.160218_bib33","doi-asserted-by":"crossref","DOI":"10.1021\/j100484a006","volume":"83","author":"Gekko","year":"1979","journal-title":"J. Phys. Chem."},{"key":"10.1074\/jbc.M110.160218_bib34","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0003-9861(79)90563-0","volume":"196","author":"Squire","year":"1979","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M110.160218_bib35","doi-asserted-by":"crossref","first-page":"e3235","DOI":"10.1371\/journal.pone.0003235","volume":"3","author":"Yoshiike","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.M110.160218_bib36","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.molcel.2010.01.001","volume":"37","author":"Hageman","year":"2010","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M110.160218_bib37","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1093\/hmg\/ddi443","volume":"15","author":"Apostol","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M110.160218_bib38","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.str.2009.08.002","volume":"17","author":"Kim","year":"2009","journal-title":"Structure"},{"key":"10.1074\/jbc.M110.160218_bib39","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1016\/j.str.2009.08.004","volume":"17","author":"Miller","year":"2009","journal-title":"Structure"},{"key":"10.1074\/jbc.M110.160218_bib40","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1038\/ncb1478","volume":"8","author":"Kitamura","year":"2006","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M110.160218_bib41","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1038\/ncb1477","volume":"8","author":"Tam","year":"2006","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M110.160218_bib42","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.1002\/j.1460-2075.1996.tb00660.x","volume":"15","author":"Freeman","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M110.160218_bib43","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1126\/science.1068408","volume":"295","author":"Hartl","year":"2002","journal-title":"Science"},{"key":"10.1074\/jbc.M110.160218_bib44","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1007\/s00018-004-4464-6","volume":"62","author":"Mayer","year":"2005","journal-title":"Cell Mol. Life Sci."},{"key":"10.1074\/jbc.M110.160218_bib45","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1126\/science.1141448","volume":"319","author":"Balch","year":"2008","journal-title":"Science"},{"key":"10.1074\/jbc.M110.160218_bib46","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1023\/B:NERE.0000014824.04728.dd","volume":"29","author":"Browne","year":"2004","journal-title":"Neurochem. Res."},{"key":"10.1074\/jbc.M110.160218_bib47","doi-asserted-by":"crossref","first-page":"3758","DOI":"10.1038\/emboj.2009.298","volume":"28","author":"Roodveldt","year":"2009","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M110.160218_bib48","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1126\/science.1124514","volume":"311","author":"Gidalevitz","year":"2006","journal-title":"Science"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820606834?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820606834?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M110.160218","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T05:31:28Z","timestamp":1641360688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820606834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":48,"journal-issue":{"issue":"49","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["S0021925820606834"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m110.160218","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}