{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T21:02:57Z","timestamp":1790974977701,"version":"4.1.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"30","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"vor","delay-in-days":3380,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1074\/jbc.m110.197947","type":"journal-article","created":{"date-parts":[[2011,6,3]],"date-time":"2011-06-03T03:08:57Z","timestamp":1307070537000},"page":"26781-26793","source":"Crossref","is-referenced-by-count":31,"title":["A Hypomorphic Mutation in Lpin1 Induces Progressively Improving Neuropathy and Lipodystrophy in the Rat"],"prefix":"10.1016","volume":"286","author":[{"given":"Joram D.","family":"Mul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Nadra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noorjahan B.","family":"Jagalur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaac J.","family":"Nijman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pim W.","family":"Toonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Jacques","family":"M\u00e9dard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Gr\u00e8s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"de Bruin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil-Soo","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos F.","family":"Brouwers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George M.","family":"Carman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-S\u00e9bastien","family":"Saulnier-Blache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dies","family":"Meijer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Chrast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Cuppen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M110.197947_bib1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.cmet.2006.08.005","volume":"4","author":"Finck","year":"2006","journal-title":"Cell Metab."},{"key":"10.1074\/jbc.M110.197947_bib2","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1101\/gad.1638008","volume":"22","author":"Nadra","year":"2008","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M110.197947_bib3","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1101\/gad.1116203","volume":"17","author":"Verheijen","year":"2003","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M110.197947_bib4","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.cmet.2004.12.002","volume":"1","author":"Phan","year":"2005","journal-title":"Cell Metab."},{"key":"10.1074\/jbc.M110.197947_bib5","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1074\/jbc.M610745200","volume":"282","author":"Donkor","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib6","doi-asserted-by":"crossref","first-page":"9210","DOI":"10.1074\/jbc.M600425200","volume":"281","author":"Han","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib7","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1074\/jbc.M609537200","volume":"282","author":"Harris","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib8","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1074\/jbc.R800059200","volume":"284","author":"Carman","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib9","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/83685","volume":"27","author":"P\u00e9terfy","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M110.197947_bib10","doi-asserted-by":"crossref","first-page":"32883","DOI":"10.1074\/jbc.M503885200","volume":"280","author":"P\u00e9terfy","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib11","doi-asserted-by":"crossref","first-page":"29968","DOI":"10.1074\/jbc.M109.023663","volume":"284","author":"Donkor","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib12","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.febslet.2007.11.014","volume":"582","author":"Reue","year":"2008","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M110.197947_bib13","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1128\/MCB.01671-09","volume":"30","author":"Kim","year":"2010","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M110.197947_bib14","doi-asserted-by":"crossref","first-page":"11955","DOI":"10.1016\/S0021-9258(18)99050-2","volume":"266","author":"Langner","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib15","doi-asserted-by":"crossref","first-page":"12089","DOI":"10.1523\/JNEUROSCI.2029-09.2009","volume":"29","author":"Douglas","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M110.197947_bib16","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/01.fpc.0000184960.82903.8f","volume":"16","author":"Smits","year":"2006","journal-title":"Pharmacogen. Genomics"},{"key":"10.1074\/jbc.M110.197947_bib17","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1471-2164-9-95","volume":"9","author":"Nijman","year":"2008","journal-title":"BMC Genomics"},{"key":"10.1074\/jbc.M110.197947_bib18","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1093\/carcin\/bgn094","volume":"29","author":"van Boxtel","year":"2008","journal-title":"Carcinogenesis"},{"key":"10.1074\/jbc.M110.197947_bib19","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/j.mcn.2007.04.010","volume":"35","author":"de Preux","year":"2007","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1074\/jbc.M110.197947_bib20","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/y59-099","volume":"37","author":"Bligh","year":"1959","journal-title":"Can. J. Biochem. Physiol."},{"key":"10.1074\/jbc.M110.197947_bib21","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1074\/jbc.271.5.2839","volume":"271","author":"Cui","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib22","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF02668129","volume":"1","author":"Rouser","year":"1966","journal-title":"Lipids"},{"key":"10.1074\/jbc.M110.197947_bib23","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1073\/pnas.94.6.2339","volume":"94","author":"Br\u00fcgger","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.197947_bib24","author":"Brouwers","year":"2011","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M110.197947_bib25","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.jmb.2006.06.049","volume":"361","author":"Burroughs","year":"2006","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M110.197947_bib26","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S1388-1981(00)00081-0","volume":"1487","author":"Roberts","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M110.197947_bib27","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1146\/annurev.cellbio.24.110707.175344","volume":"25","author":"Nohturfft","year":"2009","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1074\/jbc.M110.197947_bib28","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1177\/33.8.4020099","volume":"33","author":"Fowler","year":"1985","journal-title":"J. Histochem. Cytochem."},{"key":"10.1074\/jbc.M110.197947_bib29","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1006\/mcne.1996.0052","volume":"8","author":"Zorick","year":"1996","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1074\/jbc.M110.197947_bib30","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1126\/science.273.5274.507","volume":"273","author":"Jaegle","year":"1996","journal-title":"Science"},{"key":"10.1074\/jbc.M110.197947_bib31","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1038\/sj.embor.7400573","volume":"7","author":"Ghislain","year":"2006","journal-title":"EMBO Rep."},{"key":"10.1074\/jbc.M110.197947_bib32","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/nature05483","volume":"444","author":"Rosen","year":"2006","journal-title":"Nature"},{"key":"10.1074\/jbc.M110.197947_bib33","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1097\/01.mol.0000180166.08196.07","volume":"16","author":"Makowski","year":"2005","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1074\/jbc.M110.197947_bib34","doi-asserted-by":"crossref","first-page":"E477","DOI":"10.1152\/ajpendo.00154.2009","volume":"298","author":"Mul","year":"2010","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1074\/jbc.M110.197947_bib35","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1002\/humu.21071","volume":"30","author":"Rio Frio","year":"2009","journal-title":"Hum. Mutat."},{"key":"10.1074\/jbc.M110.197947_bib36","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1007\/s00018-009-0177-1","volume":"67","author":"Nicholson","year":"2010","journal-title":"Cell Mol. Life Sci."},{"key":"10.1074\/jbc.M110.197947_bib37","doi-asserted-by":"crossref","first-page":"29558","DOI":"10.1074\/jbc.M403506200","volume":"279","author":"Phan","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.197947_bib38","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.ajhg.2008.09.002","volume":"83","author":"Zeharia","year":"2008","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/jbc.M110.197947_bib39","doi-asserted-by":"crossref","first-page":"E1564","DOI":"10.1002\/humu.21282","volume":"31","author":"Michot","year":"2010","journal-title":"Hum. Mutat."},{"key":"10.1074\/jbc.M110.197947_bib40","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/mus.10500","volume":"29","author":"Spiekerkoetter","year":"2004","journal-title":"Muscle Nerve"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819484974?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819484974?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M110.197947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T19:15:01Z","timestamp":1641150901000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819484974"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":40,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S0021925819484974"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m110.197947","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}