{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T09:37:47Z","timestamp":1791279467178,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","issue":"22","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"vor","delay-in-days":3389,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1074\/jbc.m110.206151","type":"journal-article","created":{"date-parts":[[2011,4,13]],"date-time":"2011-04-13T02:40:41Z","timestamp":1302662441000},"page":"19597-19604","source":"Crossref","is-referenced-by-count":46,"title":["Fibroblast Growth Factor Receptor 3 (FGFR3) Is a Strong Heat Shock Protein 90 (Hsp90) Client"],"prefix":"10.1016","volume":"286","author":[{"given":"Melanie B.","family":"Laederich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine R.","family":"Degnin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory P.","family":"Lunstrum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Holden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William A.","family":"Horton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M110.206151_bib1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.cytogfr.2005.01.001","volume":"16","author":"Eswarakumar","year":"2005","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1074\/jbc.M110.206151_bib2","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.pharmthera.2009.10.001","volume":"125","author":"Knights","year":"2010","journal-title":"Pharmacol. Ther"},{"key":"10.1074\/jbc.M110.206151_bib3","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.cytogfr.2005.02.003","volume":"16","author":"Ornitz","year":"2005","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1074\/jbc.M110.206151_bib4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1038\/12615","volume":"23","author":"Cappellen","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M110.206151_bib5","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1038\/ng0797-260","volume":"16","author":"Chesi","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M110.206151_bib6","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/MOP.0b013e32833b7a69","volume":"22","author":"Laederich","year":"2010","journal-title":"Curr. Opin. Pediatr."},{"key":"10.1074\/jbc.M110.206151_bib7","first-page":"3919","volume":"9","author":"Borkovich","year":"1989","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M110.206151_bib8","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/nrm2918","volume":"11","author":"Taipale","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1074\/jbc.M110.206151_bib9","doi-asserted-by":"crossref","first-page":"3851","DOI":"10.1016\/j.yexcr.2007.06.022","volume":"313","author":"Theodoraki","year":"2007","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M110.206151_bib10","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/nsmb885","volume":"12","author":"Xu","year":"2005","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1074\/jbc.M110.206151_bib11","doi-asserted-by":"crossref","first-page":"10686","DOI":"10.1158\/0008-5472.CAN-05-2632","volume":"65","author":"da Rocha Dias","year":"2005","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M110.206151_bib12","doi-asserted-by":"crossref","first-page":"6401","DOI":"10.1158\/0008-5472.CAN-05-0933","volume":"65","author":"Shimamura","year":"2005","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M110.206151_bib13","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S1357-2725(02)00394-1","volume":"35","author":"Murata","year":"2003","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1074\/jbc.M110.206151_bib14","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.2174\/156802609789895728","volume":"9","author":"Kim","year":"2009","journal-title":"Curr. Top Med. Chem."},{"key":"10.1074\/jbc.M110.206151_bib15","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.molmed.2004.04.006","volume":"10","author":"Kamal","year":"2004","journal-title":"Trends Mol. Med."},{"key":"10.1074\/jbc.M110.206151_bib16","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1038\/nm1298","volume":"11","author":"Waza","year":"2005","journal-title":"Nat. Med."},{"key":"10.1074\/jbc.M110.206151_bib17","doi-asserted-by":"crossref","first-page":"5115","DOI":"10.1523\/JNEUROSCI.1242-07.2007","volume":"27","author":"Adachi","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M110.206151_bib18","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/j.molcel.2007.06.028","volume":"27","author":"Chen","year":"2007","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M110.206151_bib19","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1073\/pnas.2237184100","volume":"101","author":"Cho","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.206151_bib20","first-page":"123","volume":"2","author":"Chiosis","year":"2003","journal-title":"Mol. Cancer Ther."},{"key":"10.1074\/jbc.M110.206151_bib21","doi-asserted-by":"crossref","first-page":"22685","DOI":"10.1074\/jbc.M100602200","volume":"276","author":"Sweeney","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib22","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1006\/meth.1999.0933","volume":"20","author":"VanSlyke","year":"2000","journal-title":"Methods"},{"key":"10.1074\/jbc.M110.206151_bib23","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1002\/j.1460-2075.1996.tb00577.x","volume":"15","author":"Avantaggiati","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M110.206151_bib24","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.cellsig.2008.04.001","volume":"20","author":"Guo","year":"2008","journal-title":"Cell Signal"},{"key":"10.1074\/jbc.M110.206151_bib25","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/ng0395-321","volume":"9","author":"Tavormina","year":"1995","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M110.206151_bib26","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0014-5793(02)03255-6","volume":"528","author":"Monsonego-Ornan","year":"2002","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M110.206151_bib27","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jmb.2006.01.058","volume":"357","author":"Lievens","year":"2006","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M110.206151_bib28","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1093\/carcin\/bgi290","volume":"27","author":"Bernard-Pierrot","year":"2006","journal-title":"Carcinogenesis"},{"key":"10.1074\/jbc.M110.206151_bib29","doi-asserted-by":"crossref","first-page":"21710","DOI":"10.1074\/jbc.M602014200","volume":"281","author":"Germano","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib30","doi-asserted-by":"crossref","first-page":"3702","DOI":"10.1074\/jbc.M006864200","volume":"276","author":"Xu","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib31","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1379\/1466-1268(1998)003<0100:ARBTTN>2.3.CO;2","volume":"3","author":"Schulte","year":"1998","journal-title":"Cell Stress Chaperones"},{"key":"10.1074\/jbc.M110.206151_bib32","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1007\/s002800050817","volume":"42","author":"Schulte","year":"1998","journal-title":"Cancer Chemother Pharmacol"},{"key":"10.1074\/jbc.M110.206151_bib33","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1002\/jcb.21859","volume":"105","author":"Jeong","year":"2008","journal-title":"J. Cell. Biochem."},{"key":"10.1074\/jbc.M110.206151_bib34","doi-asserted-by":"crossref","first-page":"35381","DOI":"10.1074\/jbc.M109.051532","volume":"284","author":"Zhang","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib35","doi-asserted-by":"crossref","first-page":"14361","DOI":"10.1074\/jbc.M512613200","volume":"281","author":"Citri","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib36","doi-asserted-by":"crossref","first-page":"4921","DOI":"10.1074\/jbc.M808436200","volume":"284","author":"Gould","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib37","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.cellsig.2008.12.011","volume":"21","author":"Hikri","year":"2009","journal-title":"Cell Signal"},{"key":"10.1074\/jbc.M110.206151_bib38","doi-asserted-by":"crossref","first-page":"e1066","DOI":"10.1371\/journal.pone.0001066","volume":"2","author":"Margineantu","year":"2007","journal-title":"PLoS. One"},{"key":"10.1074\/jbc.M110.206151_bib39","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.1073\/pnas.0910717107","volume":"107","author":"Sun","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.206151_bib40","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1126\/science.286.5438.309","volume":"286","author":"Joazeiro","year":"1999","journal-title":"Science"},{"key":"10.1074\/jbc.M110.206151_bib41","doi-asserted-by":"crossref","first-page":"13829","DOI":"10.1074\/jbc.M209640200","volume":"278","author":"Zhou","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib42","doi-asserted-by":"crossref","first-page":"3942","DOI":"10.1093\/hmg\/ddn296","volume":"17","author":"Morishima","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M110.206151_bib43","doi-asserted-by":"crossref","first-page":"12847","DOI":"10.1073\/pnas.202365899","volume":"99","author":"Xu","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.206151_bib44","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1172\/JCI38017","volume":"119","author":"Qing","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M110.206151_bib45","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.yexcr.2004.03.011","volume":"297","author":"Krejci","year":"2004","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M110.206151_bib46","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1038\/sj.embor.7400300","volume":"5","author":"Citri","year":"2004","journal-title":"EMBO Rep"},{"key":"10.1074\/jbc.M110.206151_bib47","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1096\/fj.05-5258fje","volume":"20","author":"Li","year":"2006","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M110.206151_bib48","doi-asserted-by":"crossref","first-page":"39975","DOI":"10.1074\/jbc.M406882200","volume":"279","author":"Prince","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.206151_bib49","doi-asserted-by":"crossref","first-page":"2866","DOI":"10.1073\/pnas.0914157107","volume":"107","author":"Bae","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.206151_bib50","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1126\/science.1191542","volume":"329","author":"Okiyoneda","year":"2010","journal-title":"Science"},{"key":"10.1074\/jbc.M110.206151_bib51","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1002\/pmic.200700615","volume":"7","author":"Vecchione","year":"2007","journal-title":"Proteomics"},{"key":"10.1074\/jbc.M110.206151_bib52","doi-asserted-by":"crossref","first-page":"5631","DOI":"10.1158\/1078-0432.CCR-05-0398","volume":"11","author":"Terry","year":"2005","journal-title":"Clin Cancer Res."},{"key":"10.1074\/jbc.M110.206151_bib53","doi-asserted-by":"crossref","first-page":"2792","DOI":"10.1158\/1078-0432.CCR-09-3112","volume":"16","author":"Nakashima","year":"2010","journal-title":"Clin. Cancer Res."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820510387?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820510387?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M110.206151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T22:53:29Z","timestamp":1641336809000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820510387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":53,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0021925820510387"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m110.206151","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}