{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T08:33:46Z","timestamp":1778747626892,"version":"3.51.4"},"reference-count":60,"publisher":"Elsevier BV","issue":"26","license":[{"start":{"date-parts":[[2011,7,1]],"date-time":"2011-07-01T00:00:00Z","timestamp":1309478400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,30]],"date-time":"2020-10-30T00:00:00Z","timestamp":1604016000000},"content-version":"vor","delay-in-days":3409,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2011,7]]},"DOI":"10.1074\/jbc.m110.215814","type":"journal-article","created":{"date-parts":[[2011,5,11]],"date-time":"2011-05-11T00:18:15Z","timestamp":1305073095000},"page":"22894-22904","source":"Crossref","is-referenced-by-count":64,"title":["Mechanism of Amylin Fibrillization Enhancement by Heparin"],"prefix":"10.1016","volume":"286","author":[{"given":"Suman","family":"Jha","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharadrao M.","family":"Patil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Craig E.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nathan N.","family":"Alder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei T.","family":"Alexandrescu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M110.215814_bib1","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/dmrr.340","volume":"19","author":"Green","year":"2003","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1074\/jbc.M110.215814_bib2","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/nm0410-388","volume":"16","author":"Newgard","year":"2010","journal-title":"Nat. Med."},{"key":"10.1074\/jbc.M110.215814_bib3","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1126\/science.1104345","volume":"307","author":"Rhodes","year":"2005","journal-title":"Science"},{"key":"10.1074\/jbc.M110.215814_bib4","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1126\/science.1104346","volume":"307","author":"O'Rahilly","year":"2005","journal-title":"Science"},{"key":"10.1074\/jbc.M110.215814_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1210\/edrv-15-2-163","volume":"15","author":"Cooper","year":"1994","journal-title":"Endocr. Rev."},{"key":"10.1074\/jbc.M110.215814_bib6","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1146\/annurev.biochem.75.101304.123901","volume":"75","author":"Chiti","year":"2006","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M110.215814_bib7","doi-asserted-by":"crossref","first-page":"13505","DOI":"10.1021\/bi701427q","volume":"46","author":"Luca","year":"2007","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib8","doi-asserted-by":"crossref","first-page":"6016","DOI":"10.1021\/bi702518m","volume":"47","author":"Meng","year":"2008","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib9","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1038\/368756a0","volume":"368","author":"Lorenzo","year":"1994","journal-title":"Nature"},{"key":"10.1074\/jbc.M110.215814_bib10","doi-asserted-by":"crossref","first-page":"11338","DOI":"10.1021\/bi020314u","volume":"41","author":"Anguiano","year":"2002","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.chemphyslip.2009.03.008","volume":"160","author":"Engel","year":"2009","journal-title":"Chem. Phys. Lipids"},{"key":"10.1074\/jbc.M110.215814_bib12","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1210\/er.2007-0037","volume":"29","author":"Haataja","year":"2008","journal-title":"Endocr. Rev."},{"key":"10.1074\/jbc.M110.215814_bib13","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2337\/diabetes.48.3.491","volume":"48","author":"Janson","year":"1999","journal-title":"Diabetes"},{"key":"10.1074\/jbc.M110.215814_bib14","first-page":"169","volume":"6","author":"Zdrojewicz","year":"2006","journal-title":"Diabetologia Do\u0153swiadczalna i Kliniczna"},{"key":"10.1074\/jbc.M110.215814_bib15","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1093\/ilar.47.3.225","volume":"47","author":"Matveyenko","year":"2006","journal-title":"ILAR J."},{"key":"10.1074\/jbc.M110.215814_bib16","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.2337\/diab.45.9.1279","volume":"45","author":"Sakagashira","year":"1996","journal-title":"Diabetes"},{"key":"10.1074\/jbc.M110.215814_bib17","doi-asserted-by":"crossref","first-page":"242","DOI":"10.3109\/13506120108993820","volume":"8","author":"Ma","year":"2001","journal-title":"Amyloid"},{"key":"10.1074\/jbc.M110.215814_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1110\/ps.04887005","volume":"14","author":"Alexandrescu","year":"2005","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.M110.215814_bib19","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1042\/bj20030852","volume":"377","author":"Jaikaran","year":"2004","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M110.215814_bib20","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1110\/ps.036350.108","volume":"17","author":"Knight","year":"2008","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.M110.215814_bib21","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1016\/j.bbamem.2007.01.022","volume":"1768","author":"Jayasinghe","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M110.215814_bib22","doi-asserted-by":"crossref","first-page":"8973","DOI":"10.1021\/ja1007867","volume":"132","author":"Brender","year":"2010","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M110.215814_bib23","doi-asserted-by":"crossref","first-page":"9228","DOI":"10.1021\/bi0510936","volume":"45","author":"Abedini","year":"2006","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib24","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1046\/j.1471-4159.1999.721681.x","volume":"72","author":"Castillo","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1074\/jbc.M110.215814_bib25","doi-asserted-by":"crossref","first-page":"31617","DOI":"10.1074\/jbc.272.50.31617","volume":"272","author":"Watson","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.215814_bib26","first-page":"951","volume":"116","author":"Young","year":"1992","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1074\/jbc.M110.215814_bib27","series-title":"Biochemistry","first-page":"234","author":"Garrett","year":"1999"},{"key":"10.1074\/jbc.M110.215814_bib28","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/13506120309041728","volume":"10","author":"Ancsin","year":"2003","journal-title":"Amyloid"},{"key":"10.1074\/jbc.M110.215814_bib29","doi-asserted-by":"crossref","first-page":"612","DOI":"10.2337\/diabetes.47.4.612","volume":"47","author":"Castillo","year":"1998","journal-title":"Diabetes"},{"key":"10.1074\/jbc.M110.215814_bib30","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0003-9861(03)00116-4","volume":"413","author":"Potter-Perigo","year":"2003","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M110.215814_bib31","doi-asserted-by":"crossref","first-page":"16611","DOI":"10.1074\/jbc.M008423200","volume":"276","author":"Park","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.215814_bib32","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1006\/jsbi.2000.4222","volume":"130","author":"Kisilevsky","year":"2000","journal-title":"J. Struct. Biol."},{"key":"10.1074\/jbc.M110.215814_bib33","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jmb.2009.07.077","volume":"393","author":"Williamson","year":"2009","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M110.215814_bib34","doi-asserted-by":"crossref","first-page":"16284","DOI":"10.1021\/bi051432v","volume":"44","author":"Abedini","year":"2005","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib35","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1110\/ps.041266605","volume":"14","author":"Hortschansky","year":"2005","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.M110.215814_bib36","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1038\/nbt896","volume":"21","author":"Jares-Erijman","year":"2003","journal-title":"Nat. Biotechnol."},{"key":"10.1074\/jbc.M110.215814_bib37","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1021\/bi011711s","volume":"41","author":"Cohlberg","year":"2002","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib38","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1210\/endo-127-1-126","volume":"127","author":"Miyazaki","year":"1990","journal-title":"Endocrinology"},{"key":"10.1074\/jbc.M110.215814_bib39","doi-asserted-by":"crossref","first-page":"34272","DOI":"10.1074\/jbc.M109.049809","volume":"284","author":"Xue","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.215814_bib40","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1021\/bi011944j","volume":"41","author":"Goger","year":"2002","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib41","doi-asserted-by":"crossref","first-page":"16462","DOI":"10.1074\/jbc.C300049200","volume":"278","author":"Ban","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.215814_bib42","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1002\/pro.5560020312","volume":"2","author":"LeVine","year":"1993","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.M110.215814_bib43","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1021\/bi101908m","volume":"50","author":"Patil","year":"2011","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib44","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1093\/oxfordjournals.jbchem.a133180","volume":"89","author":"Uchiyama","year":"1981","journal-title":"J. Biochem."},{"key":"10.1074\/jbc.M110.215814_bib45","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0076-6879(06)13005-0","volume":"413","author":"Ban","year":"2006","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M110.215814_bib46","doi-asserted-by":"crossref","first-page":"4250","DOI":"10.1096\/fj.09-153551","volume":"24","author":"Valle-Delgado","year":"2010","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M110.215814_bib47","doi-asserted-by":"crossref","first-page":"3614","DOI":"10.1111\/j.1742-4658.2006.05367.x","volume":"273","author":"Konarkowska","year":"2006","journal-title":"FEBS J."},{"key":"10.1074\/jbc.M110.215814_bib48","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/nature09768","volume":"470","author":"Sandberg","year":"2011","journal-title":"Nature"},{"key":"10.1074\/jbc.M110.215814_bib49","doi-asserted-by":"crossref","first-page":"S92","DOI":"10.25011\/cim.v30i4.2870","volume":"30","author":"Potter","year":"2007","journal-title":"Clin. Invest. Med."},{"key":"10.1074\/jbc.M110.215814_bib50","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1042\/bj2930849","volume":"293","author":"Mulloy","year":"1993","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M110.215814_bib51","doi-asserted-by":"crossref","first-page":"12998","DOI":"10.1021\/ja8026345","volume":"130","author":"Zhang","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M110.215814_bib52","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.jmb.2009.10.064","volume":"395","author":"Khan","year":"2010","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M110.215814_bib53","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0076-6879(09)66010-9","volume":"466","author":"Sheftic","year":"2009","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M110.215814_bib54","doi-asserted-by":"crossref","first-page":"2357","DOI":"10.1073\/pnas.0437842100","volume":"100","author":"Raman","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M110.215814_bib55","doi-asserted-by":"crossref","first-page":"12806","DOI":"10.1021\/bi0610653","volume":"45","author":"Calamai","year":"2006","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M110.215814_bib56","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/S0197-4580(02)00003-9","volume":"23","author":"Bergamaschini","year":"2002","journal-title":"Neurobiol. Aging"},{"key":"10.1074\/jbc.M110.215814_bib57","doi-asserted-by":"crossref","first-page":"4181","DOI":"10.1523\/JNEUROSCI.0550-04.2004","volume":"24","author":"Bergamaschini","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M110.215814_bib58","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/glycob\/cwp205","volume":"20","author":"Sandwall","year":"2010","journal-title":"Glycobiology"},{"key":"10.1074\/jbc.M110.215814_bib59","doi-asserted-by":"crossref","first-page":"32471","DOI":"10.1074\/jbc.M709870200","volume":"283","author":"Bravo","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110.215814_bib60","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1007\/s00249-010-0581-3","volume":"39","author":"Madine","year":"2010","journal-title":"Eur. Biophys. J."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819488273?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819488273?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M110.215814","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T19:24:44Z","timestamp":1641151484000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819488273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,7]]},"references-count":60,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["S0021925819488273"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m110.215814","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2011,7]]}}}