{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T07:59:29Z","timestamp":1789891169708,"version":"4.0.1"},"reference-count":57,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2002,2,1]],"date-time":"2002-02-01T00:00:00Z","timestamp":1012521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T00:00:00Z","timestamp":1608768000000},"content-version":"vor","delay-in-days":6901,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2002,2]]},"DOI":"10.1074\/jbc.m110154200","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T11:03:26Z","timestamp":1027681406000},"page":"5583-5587","source":"Crossref","is-referenced-by-count":58,"title":["JEAP, a Novel Component of Tight Junctions in Exocrine Cells"],"prefix":"10.1016","volume":"277","author":[{"given":"Miyuki","family":"Nishimura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayumi","family":"Kakizaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Ono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Morimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshio","family":"Imai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshimi","family":"Takai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M110154200_bib1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1083\/jcb.17.2.375","volume":"17","author":"Farquhar","year":"1963","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib2","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s002329900380","volume":"163","author":"Yap","year":"1998","journal-title":"J. Membr. Biol."},{"key":"10.1074\/jbc.M110154200_bib3","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1146\/annurev.physiol.60.1.161","volume":"60","author":"Cereijido","year":"1998","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.M110154200_bib4","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1146\/annurev.physiol.60.1.121","volume":"60","author":"Mitic","year":"1998","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.M110154200_bib5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1146\/annurev.physiol.60.1.105","volume":"60","author":"Spring","year":"1998","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.M110154200_bib6","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/S0955-0674(99)00016-2","volume":"11","author":"Tsukita","year":"1999","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib7","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1038\/35067088","volume":"2","author":"Tsukita","year":"2001","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"key":"10.1074\/jbc.M110154200_bib8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1083\/jcb.143.2.391","volume":"143","author":"Furuse","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib9","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1073\/pnas.96.2.511","volume":"96","author":"Morita","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M110154200_bib10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1083\/jcb.133.1.43","volume":"133","author":"Ando-Akatsuka","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib11","doi-asserted-by":"crossref","first-page":"1777","DOI":"10.1083\/jcb.123.6.1777","volume":"123","author":"Furuse","year":"1993","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib12","first-page":"91","volume":"251","author":"Aurrand-Lions","year":"2000","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1074\/jbc.M110154200_bib13","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1083\/jcb.142.1.117","volume":"142","author":"Martin-Padura","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib14","doi-asserted-by":"crossref","first-page":"19139","DOI":"10.1074\/jbc.M003189200","volume":"275","author":"Palmeri","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib15","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1083\/jcb.103.3.755","volume":"103","author":"Stevenson","year":"1986","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib16","doi-asserted-by":"crossref","first-page":"3460","DOI":"10.1073\/pnas.88.8.3460","volume":"88","author":"Gumbiner","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M110154200_bib17","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1083\/jcb.141.1.199","volume":"141","author":"Haskins","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib18","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/333272a0","volume":"333","author":"Citi","year":"1988","journal-title":"Nature"},{"key":"10.1074\/jbc.M110154200_bib19","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1083\/jcb.120.2.477","volume":"120","author":"Zhong","year":"1993","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib20","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1083\/jcb.134.4.1003","volume":"134","author":"Keon","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib21","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1083\/jcb.125.3.583","volume":"125","author":"Weber","year":"1994","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib22","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1083\/jcb.143.1.95","volume":"143","author":"Izumi","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib23","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/35019573","volume":"2","author":"Joberty","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib24","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1038\/35019582","volume":"2","author":"Lin","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib25","doi-asserted-by":"crossref","first-page":"31589","DOI":"10.1074\/jbc.272.50.31589","volume":"272","author":"Dobrosotskaya","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib26","doi-asserted-by":"crossref","first-page":"7810","DOI":"10.1038\/sj.onc.1203153","volume":"18","author":"Ide","year":"1999","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M110154200_bib27","doi-asserted-by":"crossref","first-page":"5981","DOI":"10.1074\/jbc.274.9.5981","volume":"274","author":"Itoh","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib28","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1083\/jcb.147.6.1351","volume":"147","author":"Itoh","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib29","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1083\/jcb.127.6.1617","volume":"127","author":"Furuse","year":"1994","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib30","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1083\/jcb.138.1.181","volume":"138","author":"Itoh","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib31","doi-asserted-by":"crossref","first-page":"29745","DOI":"10.1074\/jbc.273.45.29745","volume":"273","author":"Fanning","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib32","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1083\/jcb.151.4.825","volume":"151","author":"Wittchen","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib33","doi-asserted-by":"crossref","first-page":"20520","DOI":"10.1074\/jbc.M905251199","volume":"275","author":"Bazzoni","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib34","doi-asserted-by":"crossref","first-page":"27979","DOI":"10.1074\/jbc.M002363200","volume":"275","author":"Ebnet","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib35","doi-asserted-by":"crossref","first-page":"21477","DOI":"10.1074\/jbc.M909741199","volume":"275","author":"Wu","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib36","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1073\/pnas.97.8.4233","volume":"97","author":"Wu","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M110154200_bib37","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1006\/bbrc.1999.1619","volume":"265","author":"Ohtsuka","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M110154200_bib38","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/S0960-9822(00)00535-2","volume":"10","author":"Qiu","year":"2000","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M110154200_bib39","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1083\/jcb.200103047","volume":"154","author":"Itoh","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib40","doi-asserted-by":"crossref","first-page":"3738","DOI":"10.1093\/emboj\/20.14.3738","volume":"20","author":"Ebnet","year":"2001","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M110154200_bib41","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1083\/jcb.147.7.1569","volume":"147","author":"Cordenonsi","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib42","doi-asserted-by":"crossref","first-page":"3062","DOI":"10.1073\/pnas.97.7.3062","volume":"97","author":"Misawa","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M110154200_bib43","doi-asserted-by":"crossref","first-page":"15036","DOI":"10.1074\/jbc.272.23.15036","volume":"272","author":"Imai","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib44","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.1038\/sj.onc.1203631","volume":"19","author":"Ono","year":"2000","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M110154200_bib45","doi-asserted-by":"crossref","first-page":"5234","DOI":"10.1093\/nar\/20.19.5234","volume":"20","author":"Baker","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M110154200_bib46","first-page":"324","volume":"24","author":"Onishi","year":"1996","journal-title":"Exp. Hematol."},{"key":"10.1074\/jbc.M110154200_bib47","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1083\/jcb.145.3.539","volume":"145","author":"Takahashi","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib48","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1083\/jcb.139.2.517","volume":"139","author":"Mandai","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib49","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1083\/jcb.144.5.1001","volume":"144","author":"Mandai","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib50","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1046\/j.1365-2443.1999.00283.x","volume":"4","author":"Asakura","year":"1999","journal-title":"Genes Cells"},{"key":"10.1074\/jbc.M110154200_bib51","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1126\/science.252.5009.1162","volume":"252","author":"Lupas","year":"1991","journal-title":"Science"},{"key":"10.1074\/jbc.M110154200_bib52","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0968-0004(96)10052-9","volume":"21","author":"Lupas","year":"1996","journal-title":"Trends Biochem. Sci."},{"key":"10.1074\/jbc.M110154200_bib53","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1126\/science.275.5296.73","volume":"275","author":"Songyang","year":"1997","journal-title":"Science"},{"key":"10.1074\/jbc.M110154200_bib54","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1083\/jcb.121.3.491","volume":"121","author":"Itoh","year":"1993","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib55","doi-asserted-by":"crossref","first-page":"29816","DOI":"10.1074\/jbc.M002450200","volume":"275","author":"Nusrat","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M110154200_bib56","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1083\/jcb.153.2.263","volume":"153","author":"Furuse","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M110154200_bib57","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1083\/jcb.152.6.1247","volume":"152","author":"Troyanovsky","year":"2001","journal-title":"J. Cell Biol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819826005?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819826005?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M110154200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T19:45:15Z","timestamp":1641239115000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819826005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,2]]},"references-count":57,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2002,2]]}},"alternative-id":["S0021925819826005"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m110154200","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1003527.37855","asserted-by":"object"}]},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2002,2]]}}}