{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:40:54Z","timestamp":1789713654748,"version":"4.0.1"},"reference-count":57,"publisher":"Elsevier BV","issue":"28","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T00:00:00Z","timestamp":1599436800000},"content-version":"vor","delay-in-days":2625,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1074\/jbc.m112.426627","type":"journal-article","created":{"date-parts":[[2013,5,24]],"date-time":"2013-05-24T01:16:53Z","timestamp":1369358213000},"page":"20392-20403","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"title":["Structure and Function of Hainantoxin-III, a Selective Antagonist of Neuronal Tetrodotoxin-sensitive Voltage-gated Sodium Channels Isolated from the Chinese Bird Spider Ornithoctonus hainana"],"prefix":"10.1016","volume":"288","author":[{"given":"Zhonghua","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianfu","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meichun","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijun","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songping","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M112.426627_bib1","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1113\/jphysiol.2011.224204","article-title":"Voltage-gated sodium channels at 60. Structure, function, and pathophysiology","volume":"590","author":"Catterall","year":"2012","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M112.426627_bib2","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0896-6273(00)81133-2","article-title":"From ionic currents to molecular mechanisms. The structure and function of voltage-gated sodium channels","volume":"26","author":"Catterall","year":"2000","journal-title":"Neuron"},{"key":"10.1074\/jbc.M112.426627_bib3","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1146\/annurev-neuro-060909-153234","article-title":"Sodium channels in normal and pathological pain","volume":"33","author":"Dib-Hajj","year":"2010","journal-title":"Annu. Rev. Neurosci"},{"key":"10.1074\/jbc.M112.426627_bib4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/gb-2003-4-3-207","article-title":"Overview of the voltage-gated sodium channel family","volume":"4","author":"Yu","year":"2003","journal-title":"Genome Biol"},{"key":"10.1074\/jbc.M112.426627_bib5","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1111\/j.1526-4637.2009.00719.x","article-title":"Voltage-gated sodium channels. Therapeutic targets for pain","volume":"10","author":"Dib-Hajj","year":"2009","journal-title":"Pain Med"},{"key":"10.1074\/jbc.M112.426627_bib6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/1744-8069-7-16","article-title":"Are voltage-gated sodium channels on the dorsal root ganglion involved in the development of neuropathic pain?","volume":"7","author":"Wang","year":"2011","journal-title":"Mol. Pain"},{"key":"10.1074\/jbc.M112.426627_bib7","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1172\/JCI42843","article-title":"Nociceptors. The sensors of the pain pathway","volume":"120","author":"Dubin","year":"2010","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.M112.426627_bib8","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/S0300-9084(00)01174-3","article-title":"Molecular mechanisms of neurotoxin action on voltage-gated sodium channels","volume":"82","author":"Cest\u00e8le","year":"2000","journal-title":"Biochimie"},{"key":"10.1074\/jbc.M112.426627_bib9","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.tips.2009.12.007","article-title":"Targeting voltage sensors in sodium channels with spider toxins","volume":"31","author":"Bosmans","year":"2010","journal-title":"Trends Pharmacol. Sci"},{"key":"10.1074\/jbc.M112.426627_bib10","doi-asserted-by":"crossref","first-page":"407","DOI":"10.4161\/chan.2.6.7429","article-title":"Interaction between voltage-gated sodium channels and the neurotoxin, tetrodotoxin","volume":"2","author":"Lee","year":"2008","journal-title":"Channels"},{"key":"10.1074\/jbc.M112.426627_bib11","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.2174\/138161208785777423","article-title":"Animal peptides targeting voltage-activated sodium channels","volume":"14","author":"Billen","year":"2008","journal-title":"Curr. Pharm. Des"},{"key":"10.1074\/jbc.M112.426627_bib12","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.toxicon.2006.09.022","article-title":"Voltage-gated ion channels and gating modifier toxins","volume":"49","author":"Catterall","year":"2007","journal-title":"Toxicon"},{"key":"10.1074\/jbc.M112.426627_bib13","doi-asserted-by":"crossref","first-page":"71","DOI":"10.3389\/fphar.2011.00071","article-title":"Neurotoxins and their binding areas on voltage-gated sodium channels","volume":"2","author":"Stevens","year":"2011","journal-title":"Front. Pharmacol"},{"key":"10.1074\/jbc.M112.426627_bib14","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1517\/14712598.2011.621940","article-title":"Venoms as a platform for human drugs. Translating toxins into therapeutics","volume":"11","author":"King","year":"2011","journal-title":"Expert Opin. Biol. Ther"},{"key":"10.1074\/jbc.M112.426627_bib15","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1586\/epr.09.45","article-title":"Venomics as a drug discovery platform","volume":"6","author":"Escoubas","year":"2009","journal-title":"Expert Rev. Proteomics"},{"key":"10.1074\/jbc.M112.426627_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-2999(03)02190-3","article-title":"Inhibition of neuronal tetrodotoxin-sensitive Na+ channels by two spider toxins. Hainantoxin-III and hainantoxin-IV","volume":"477","author":"Xiao","year":"2003","journal-title":"Eur. J. Pharmacol"},{"key":"10.1074\/jbc.M112.426627_bib17","doi-asserted-by":"crossref","first-page":"27301","DOI":"10.1074\/jbc.M111.246876","article-title":"Common molecular determinants of tarantula huwentoxin-IV inhibition of Na+ channel voltage sensors in domains II and IV","volume":"286","author":"Xiao","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib18","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1124\/mol.110.066332","article-title":"The tarantulatoxins ProTx-II and huwentoxin-IV differentially interact with human Nav1.7 voltage sensors to inhibit channel activation and inactivation","volume":"78","author":"Xiao","year":"2010","journal-title":"Mol. Pharmacol"},{"key":"10.1074\/jbc.M112.426627_bib19","doi-asserted-by":"crossref","first-page":"27300","DOI":"10.1074\/jbc.M708447200","article-title":"Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain II voltage sensor in the closed configuration","volume":"283","author":"Xiao","year":"2008","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib20","doi-asserted-by":"crossref","first-page":"47564","DOI":"10.1074\/jbc.M204063200","article-title":"Function and solution structure of huwentoxin-IV, a potent neuronal tetrodotoxin (TTX)-sensitive sodium channel antagonist from Chinese bird spider Selenocosmia huwena","volume":"277","author":"Peng","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib21","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1002\/pro.5560021017","article-title":"Disulfide structures of highly bridged peptides. A new strategy for analysis","volume":"2","author":"Gray","year":"1993","journal-title":"Protein Sci"},{"key":"10.1074\/jbc.M112.426627_bib22","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1002\/pro.5560021018","article-title":"Echistatin disulfide bridges. Selective reduction and linkage assignment","volume":"2","author":"Gray","year":"1993","journal-title":"Protein Sci"},{"key":"10.1074\/jbc.M112.426627_bib23","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1469-7793.1997.067bo.x","article-title":"Modulation by adenosine of GABA-activated current in rat dorsal root ganglion neurons","volume":"501","author":"Hu","year":"1997","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M112.426627_bib24","series-title":"NMR of Protein and Nucleic Acids","author":"W\u00fcthrich","year":"1986"},{"key":"10.1074\/jbc.M112.426627_bib25","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1090-7807(02)00014-9","article-title":"The Xplor-NIH NMR molecular structure determination package","volume":"160","author":"Schwieters","year":"2003","journal-title":"J. Magn. Reson"},{"key":"10.1074\/jbc.M112.426627_bib26","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1021\/pr1000016","article-title":"Molecular diversification of peptide toxins from the tarantula Haplopelma hainanum (Ornithoctonus hainana) venom based on transcriptomic, peptidomic, and genomic analyses","volume":"9","author":"Tang","year":"2010","journal-title":"J. Proteome Res"},{"key":"10.1074\/jbc.M112.426627_bib27","doi-asserted-by":"crossref","first-page":"2005","DOI":"10.1016\/j.biocel.2006.06.008","article-title":"Neuronal voltage-gated sodium channel subtypes. Key roles in inflammatory and neuropathic pain","volume":"38","author":"Ekberg","year":"2006","journal-title":"Int. J. Biochem. Cell Biol"},{"key":"10.1074\/jbc.M112.426627_bib28","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1113\/jphysiol.2003.047357","article-title":"Distinct repriming and closed-state inactivation kinetics of Nav1.6 and Nav1.7 sodium channels in mouse spinal sensory neurons","volume":"551","author":"Herzog","year":"2003","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M112.426627_bib29","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1124\/mol.52.6.1095","article-title":"Voltage-dependent inhibition of N- and P-type calcium channels by the peptide toxin \u03c9-grammotoxin-SIA","volume":"52","author":"McDonough","year":"1997","journal-title":"Mol. Pharmacol"},{"key":"10.1074\/jbc.M112.426627_bib30","doi-asserted-by":"crossref","first-page":"24568","DOI":"10.1074\/jbc.M109.030841","article-title":"Synthesis, solution structure, and phylum selectivity of a spider \u03b4-toxin that slows inactivation of specific voltage-gated sodium channel subtypes","volume":"284","author":"Yamaji","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib31","doi-asserted-by":"crossref","first-page":"4643","DOI":"10.1074\/jbc.M605403200","article-title":"Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels","volume":"282","author":"Corzo","year":"2007","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib32","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1124\/jpet.110.178343","article-title":"Nav\u03b2 subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier \u03bcO-conotoxin MrVIB","volume":"338","author":"Wilson","year":"2011","journal-title":"J. Pharmacol. Exp. Ther"},{"key":"10.1074\/jbc.M112.426627_bib33","doi-asserted-by":"crossref","first-page":"18545","DOI":"10.1074\/jbc.M110.125211","article-title":"Unique bell-shaped voltage-dependent modulation of Na+ channel gating by novel insect-selective toxins from the spider Agelena orientalis","volume":"285","author":"Billen","year":"2010","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib34","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0006-3495(01)75681-0","article-title":"Interaction of SNX482 with domains III and IV inhibits activation gating of \u03b1(1E) (Cav2.3) calcium channels","volume":"81","author":"Bourinet","year":"2001","journal-title":"Biophys. J"},{"key":"10.1074\/jbc.M112.426627_bib35","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1124\/mol.105.015941","article-title":"Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes","volume":"69","author":"Bosmans","year":"2006","journal-title":"Mol. Pharmacol"},{"key":"10.1074\/jbc.M112.426627_bib36","doi-asserted-by":"crossref","first-page":"15426","DOI":"10.1073\/pnas.1112320108","article-title":"Mapping the receptor site for \u03b1-scorpion toxins on a Na+ channel voltage sensor","volume":"108","author":"Wang","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M112.426627_bib37","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/nature03873","article-title":"Voltage-sensor activation with a tarantula toxin as cargo","volume":"436","author":"Phillips","year":"2005","journal-title":"Nature"},{"key":"10.1074\/jbc.M112.426627_bib38","doi-asserted-by":"crossref","first-page":"761","DOI":"10.2174\/0929866511320070005","article-title":"Sequence-specific 1H-NMR assignment and determination of the secondary structure of Hainantoxin-III from the spider Ornithoctonus hainana","volume":"20","author":"Liu","year":"2013","journal-title":"Protein Pept. Lett"},{"key":"10.1074\/jbc.M112.426627_bib39","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1021\/bi00121a010","article-title":"The chemical shift index. A fast and simple method for the assignment of protein secondary structure through NMR spectroscopy","volume":"31","author":"Wishart","year":"1992","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M112.426627_bib40","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1002\/pro.5560031022","article-title":"A common structural motif incorporating a cystine knot and a triple-stranded \u03b2-sheet in toxic and inhibitory polypeptides","volume":"3","author":"Pallaghy","year":"1994","journal-title":"Protein Sci"},{"key":"10.1074\/jbc.M112.426627_bib41","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0041-0101(00)00160-4","article-title":"The cystine knot motif in toxins and implications for drug design","volume":"39","author":"Craik","year":"2001","journal-title":"Toxicon"},{"key":"10.1074\/jbc.M112.426627_bib42","doi-asserted-by":"crossref","first-page":"D293","DOI":"10.1093\/nar\/gkm832","article-title":"ATDB. A uni-database platform for animal toxins","volume":"36","author":"He","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M112.426627_bib43","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.toxicon.2010.05.013","article-title":"ATDB 2.0. A database integrated toxin-ion channel interaction data","volume":"56","author":"He","year":"2010","journal-title":"Toxicon"},{"key":"10.1074\/jbc.M112.426627_bib44","doi-asserted-by":"crossref","first-page":"10302","DOI":"10.1073\/pnas.1107027108","article-title":"\u03bc-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve","volume":"108","author":"Wilson","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M112.426627_bib45","doi-asserted-by":"crossref","first-page":"344","DOI":"10.4161\/chan.5112","article-title":"Docking of \u03bc-conotoxin GIIIA in the sodium channel outer vestibule","volume":"1","author":"Choudhary","year":"2007","journal-title":"Channels"},{"key":"10.1074\/jbc.M112.426627_bib46","doi-asserted-by":"crossref","first-page":"33641","DOI":"10.1074\/jbc.M111.282509","article-title":"Structure-function map of the receptor site for \u03b2-scorpion toxins in domain II of voltage-gated sodium channels","volume":"286","author":"Zhang","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib47","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/S0014-5793(03)01303-6","article-title":"Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana","volume":"555","author":"Li","year":"2003","journal-title":"FEBS Lett"},{"key":"10.1074\/jbc.M112.426627_bib48","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1007\/s00018-003-2354-x","article-title":"Isolation and characterization of hainantoxin-IV, a novel antagonist of tetrodotoxin-sensitive sodium channels from the Chinese bird spider Selenocosmia hainana","volume":"60","author":"Liu","year":"2003","journal-title":"Cell Mol. Life Sci"},{"key":"10.1074\/jbc.M112.426627_bib49","doi-asserted-by":"crossref","first-page":"37734","DOI":"10.1074\/jbc.M405765200","article-title":"Structure-activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers","volume":"279","author":"Li","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib50","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.peptides.2011.10.029","article-title":"The effects of huwentoxin-I on the voltage-gated sodium channels of rat hippocampal and cockroach dorsal unpaired median neurons","volume":"34","author":"Wang","year":"2012","journal-title":"Peptides"},{"key":"10.1074\/jbc.M112.426627_bib51","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1124\/mol.107.041046","article-title":"Inhibition of sodium channel gating by trapping the domain II voltage sensor with protoxin II","volume":"73","author":"Sokolov","year":"2008","journal-title":"Mol. Pharmacol"},{"key":"10.1074\/jbc.M112.426627_bib52","doi-asserted-by":"crossref","first-page":"12687","DOI":"10.1074\/jbc.M610462200","article-title":"Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5. Implied existence of a novel toxin binding site coupled to activation","volume":"282","author":"Smith","year":"2007","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib53","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.toxicon.2006.09.014","article-title":"ProTx-I and ProTx-II. Gating modifiers of voltage-gated sodium channels","volume":"49","author":"Priest","year":"2007","journal-title":"Toxicon"},{"key":"10.1074\/jbc.M112.426627_bib54","doi-asserted-by":"crossref","first-page":"30719","DOI":"10.1074\/jbc.M112.370742","article-title":"Mapping the interaction site for a \u03b2-scorpion toxin in the pore module of domain III of voltage-gated Na+ channels","volume":"287","author":"Zhang","year":"2012","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib55","doi-asserted-by":"crossref","first-page":"20684","DOI":"10.1074\/jbc.M109.021303","article-title":"Molecular requirements for recognition of brain voltage-gated sodium channels by scorpion \u03b1-toxins","volume":"284","author":"Kahn","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib56","doi-asserted-by":"crossref","first-page":"5045","DOI":"10.1074\/jbc.M408427200","article-title":"Common features in the functional surface of scorpion \u03b2-toxins and elements that confer specificity for insect and mammalian voltage-gated sodium channels","volume":"280","author":"Cohen","year":"2005","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M112.426627_bib57","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1002\/psc.2451","article-title":"A positively charged surface patch is important for hainantoxin-IV binding to voltage-gated sodium channels","volume":"18","author":"Liu","year":"2012","journal-title":"J. Pept. Sci"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820456091?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820456091?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M112.426627","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T19:33:04Z","timestamp":1699039984000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820456091"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":57,"journal-issue":{"issue":"28","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0021925820456091"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m112.426627","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structure and Function of Hainantoxin-III, a Selective Antagonist of Neuronal Tetrodotoxin-sensitive Voltage-gated Sodium Channels Isolated from the Chinese Bird Spider Ornithoctonus hainana","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M112.426627","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2013 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}