{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T12:40:17Z","timestamp":1791290417771,"version":"4.3.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"14","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"vor","delay-in-days":2738,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1074\/jbc.m112.445866","type":"journal-article","created":{"date-parts":[[2013,2,20]],"date-time":"2013-02-20T04:38:02Z","timestamp":1361335082000},"page":"10154-10165","source":"Crossref","is-referenced-by-count":42,"title":["Spink13, an Epididymis-specific Gene of the Kazal-type Serine Protease Inhibitor (SPINK) Family, Is Essential for the Acrosomal Integrity and Male Fertility"],"prefix":"10.1016","volume":"288","author":[{"given":"Li","family":"Ma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heguo","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zimei","family":"Ni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuanggang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wubin","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonglian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M112.445866_bib1","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/216816a0","article-title":"Sperm maturation in rabbit epididymis","volume":"216","author":"Orgebin-Crist","year":"1967","journal-title":"Nature"},{"key":"10.1074\/jbc.M112.445866_bib2","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1172\/JCI41585","article-title":"Fertilization. A sperm's journey to and interaction with the oocyte","volume":"120","author":"Ikawa","year":"2010","journal-title":"J. Clin. Invest."},{"key":"10.1074\/jbc.M112.445866_bib3","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1530\/REP-08-0132","article-title":"Novel epididymal proteins as targets for the development of post-testicular male contraception","volume":"137","author":"Sipil\u00e4","year":"2009","journal-title":"Reproduction"},{"key":"10.1074\/jbc.M112.445866_bib4","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/humupd\/dmn055","article-title":"New insights into epididymal biology and function","volume":"15","author":"Cornwall","year":"2009","journal-title":"Hum. Reprod. Update"},{"key":"10.1074\/jbc.M112.445866_bib5","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1038\/ncb1127","article-title":"An epididymis-specific \u03b2-defensin is important for the initiation of sperm maturation","volume":"6","author":"Zhou","year":"2004","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M112.445866_bib6","first-page":"73","article-title":"Plasma membrane structure and remodelling during sperm maturation in the epididymis","volume":"53","author":"Jones","year":"1998","journal-title":"J. Reprod. Fertil. Suppl."},{"key":"10.1074\/jbc.M112.445866_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/jemt.10312","article-title":"Contribution of epididymal secretory proteins for spermatozoa maturation","volume":"61","author":"Dacheux","year":"2003","journal-title":"Microsc. Res. Tech."},{"key":"10.1074\/jbc.M112.445866_bib8","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.theriogenology.2010.03.029","article-title":"Regulated serine proteinase lytic system on mammalian sperm surface. There must be a role","volume":"74","author":"Cesari","year":"2010","journal-title":"Theriogenology"},{"key":"10.1074\/jbc.M112.445866_bib9","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/jemt.10313","article-title":"Glycan modifying enzymes in luminal fluid of rat epididymis. Are they involved in altering sperm surface glycoproteins during maturation?","volume":"61","author":"Tulsiani","year":"2003","journal-title":"Microsc. Res. Tech."},{"key":"10.1074\/jbc.M112.445866_bib10","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1242\/jcs.109.10.2561","article-title":"Testicular biosynthesis and epididymal endoproteolytic processing of rat sperm surface antigen 2B1","volume":"109","author":"Jones","year":"1996","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M112.445866_bib11","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1095\/biolreprod.106.052977","article-title":"Aberrant distribution of ADAM3 in sperm from both angiotensin-converting enzyme (Ace)- and calmegin (Clgn)-deficient mice","volume":"75","author":"Yamaguchi","year":"2006","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib12","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/nm1179","article-title":"Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization","volume":"11","author":"Kondoh","year":"2005","journal-title":"Nat. Med."},{"key":"10.1074\/jbc.M112.445866_bib13","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/humupd\/dmn060","article-title":"Proprotein convertase subtilisin\/kexin type 4 in mammalian fertility. A review","volume":"15","author":"Gyamera-Acheampong","year":"2009","journal-title":"Hum. Reprod. Update"},{"key":"10.1074\/jbc.M112.445866_bib14","doi-asserted-by":"crossref","first-page":"4529","DOI":"10.1210\/endo.142.10.8422","article-title":"Primate epididymis-specific proteins. Characterization of ESC42, a novel protein containing a trefoil-like motif in monkey and human","volume":"142","author":"Liu","year":"2001","journal-title":"Endocrinology"},{"key":"10.1074\/jbc.M112.445866_bib15","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00251-007-0199-5","article-title":"The SPINK gene family and celiac disease susceptibility","volume":"59","author":"Wapenaar","year":"2007","journal-title":"Immunogenetics"},{"key":"10.1074\/jbc.M112.445866_bib16","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.1021\/ja01189a060","article-title":"Isolation of a crystalline trypsin inhibitor-anticoagulant protein from pancreas","volume":"70","author":"Kazal","year":"1948","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M112.445866_bib17","article-title":"Phylogenetic distribution of protease inhibitors of the Kazal-family within the Arthropoda","author":"van Hoef","year":"2012","journal-title":"Peptides"},{"key":"10.1074\/jbc.M112.445866_bib18","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1021\/bi00375a027","article-title":"Chicken ovomucoid. Determination of its amino acid sequence, determination of the trypsin reactive site, and preparation of all three of its domains","volume":"26","author":"Kato","year":"1987","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M112.445866_bib19","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1073\/pnas.98.4.1410","article-title":"Predicting the reactivity of proteins from their sequence alone. Kazal family of protein inhibitors of serine proteinases","volume":"98","author":"Lu","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M112.445866_bib20","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/76088","article-title":"Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis","volume":"25","author":"Witt","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M112.445866_bib21","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0014-5793(90)81273-Q","article-title":"Amino acid sequence elucidation of human acrosin-trypsin inhibitor (HUSI-II) reveals that Kazal-type proteinase inhibitors are structurally related to \u03b2-subunits of glycoprotein hormones","volume":"270","author":"Fink","year":"1990","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M112.445866_bib22","doi-asserted-by":"crossref","first-page":"8590","DOI":"10.1073\/pnas.86.21.8590","article-title":"Isolation and characterization of a 60-residue intestinal peptide structurally related to the pancreatic secretory type of trypsin inhibitor. Influence on insulin secretion","volume":"86","author":"Agerberth","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M112.445866_bib23","doi-asserted-by":"crossref","first-page":"21499","DOI":"10.1074\/jbc.274.31.21499","article-title":"LEKTI, a novel 15-domain type of human serine proteinase inhibitor","volume":"274","author":"M\u00e4gert","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M112.445866_bib24","doi-asserted-by":"crossref","first-page":"32174","DOI":"10.1074\/jbc.M109.091850","article-title":"Isolation of SPINK6 in human skin. Selective inhibitor of kallikrein-related peptidases","volume":"285","author":"Meyer-Hoffert","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M112.445866_bib25","first-page":"1521","article-title":"Molecular cloning and characterization of a novel esophageal cancer related gene","volume":"37","author":"Cui","year":"2010","journal-title":"Int. J. Oncol."},{"key":"10.1074\/jbc.M112.445866_bib26","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.bbrc.2006.08.023","article-title":"Novel epididymal protease inhibitors with Kazal or WAP family domain","volume":"349","author":"Jalkanen","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M112.445866_bib27","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1038\/jid.2008.448","article-title":"SPINK9. A selective, skin-specific Kazal-type serine protease inhibitor","volume":"129","author":"Brattsand","year":"2009","journal-title":"J. Invest. Dermatol."},{"key":"10.1074\/jbc.M112.445866_bib28","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1101\/gr.1946304","article-title":"A genomic analysis of rat proteases and protease inhibitors","volume":"14","author":"Puente","year":"2004","journal-title":"Genome Res."},{"key":"10.1074\/jbc.M112.445866_bib29","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.mrfmmm.2003.11.017","article-title":"Gene expression patterns associated with infertility in humans and rodent models","volume":"549","author":"Rockett","year":"2004","journal-title":"Mutat. Res."},{"key":"10.1074\/jbc.M112.445866_bib30","doi-asserted-by":"crossref","first-page":"3671","DOI":"10.1182\/blood-2004-04-1594","article-title":"Distinct types of primary cutaneous large B-cell lymphoma identified by gene expression profiling","volume":"105","author":"Hoefnagel","year":"2005","journal-title":"Blood"},{"key":"10.1074\/jbc.M112.445866_bib31","doi-asserted-by":"crossref","first-page":"95","DOI":"10.2340\/00015555-0769","article-title":"A new SPINK5 donor splice site mutation in siblings with Netherton syndrome","volume":"90","author":"T\u00fcys\u00fcz","year":"2010","journal-title":"Acta Derm. Venereol."},{"key":"10.1074\/jbc.M112.445866_bib32","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1007\/s10620-010-1349-4","article-title":"The prevalence of cationic trypsinogen (PRSS1) and serine protease inhibitor, Kazal type 1 (SPINK1) gene mutations in Polish patients with alcoholic and idiopathic chronic pancreatitis","volume":"56","author":"Gasiorowska","year":"2011","journal-title":"Dig. Dis. Sci."},{"key":"10.1074\/jbc.M112.445866_bib33","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1038\/aja.2011.45","article-title":"Role of the tumor-associated trypsin inhibitor SPINK1 in cancer development","volume":"13","author":"Stenman","year":"2011","journal-title":"Asian J. Androl."},{"key":"10.1074\/jbc.M112.445866_bib34","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0014-5793(91)80099-O","article-title":"Molecular cloning and sequence analysis of the cDNA encoding the human acrosin-trypsin inhibitor (HUSI-II)","volume":"278","author":"M\u00f6ritz","year":"1991","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M112.445866_bib35","doi-asserted-by":"crossref","first-page":"29108","DOI":"10.1074\/jbc.M111.244905","article-title":"Impaired spermatogenesis and fertility in mice carrying a mutation in the Spink2 gene expressed predominantly in testes","volume":"286","author":"Lee","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M112.445866_bib36","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00418-008-0425-8","article-title":"Expression pattern of serine protease inhibitor Kazal type 3 (Spink3) during mouse embryonic development","volume":"130","author":"Wang","year":"2008","journal-title":"Histochem. Cell Biol."},{"key":"10.1074\/jbc.M112.445866_bib37","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1095\/biolreprod.107.067538","article-title":"Rat caltrin protein modulates the acrosomal exocytosis during sperm capacitation","volume":"79","author":"Dematteis","year":"2008","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib38","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1095\/biolreprod.108.071589","article-title":"The novel epididymis-specific \u03b2-galactosidase-like gene Glb1l4 is essential in epididymal development and sperm maturation in rats","volume":"80","author":"Zhen","year":"2009","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib39","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1095\/biolreprod.106.054635","article-title":"RNase9, an androgen-dependent member of the RNase A family, is specifically expressed in the rat epididymis","volume":"76","author":"Zhu","year":"2007","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib40","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1093\/abbs\/36.8.571","article-title":"An effective method for raising antisera against \u03b2-defensins. Double-copy protein expression of mBin1b in E. coli","volume":"36","author":"Xiao","year":"2004","journal-title":"Acta Biochim. Biophys. Sin. (Shanghai)"},{"key":"10.1074\/jbc.M112.445866_bib41","series-title":"Antibodies: A Laboratory Manual","first-page":"139","author":"Harlow","year":"1988"},{"key":"10.1074\/jbc.M112.445866_bib42","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1095\/biolreprod60.6.1542","article-title":"Immunolocalization of CRES (cystatin-related epididymal spermatogenic) protein in the acrosomes of mouse spermatozoa","volume":"60","author":"Syntin","year":"1999","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib43","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1038\/nprot.2007.278","article-title":"A protocol for designing siRNAs with high functionality and specificity","volume":"2","author":"Birmingham","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1074\/jbc.M112.445866_bib44","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s00018-010-0478-4","article-title":"The epididymis-specific antimicrobial peptide \u03b2-defensin 15 is required for sperm motility and male fertility in the rat (Rattus norvegicus)","volume":"68","author":"Zhao","year":"2011","journal-title":"Cell Mol. Life Sci."},{"key":"10.1074\/jbc.M112.445866_bib45","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1095\/biolreprod48.2.340","article-title":"Inhibition of acrosin activity with a trypsin inhibitor blocks human sperm penetration of the zona pellucida","volume":"48","author":"Liu","year":"1993","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib46","doi-asserted-by":"crossref","first-page":"e4106","DOI":"10.1371\/journal.pone.0004106","article-title":"An epididymis-specific secretory protein HongrES1 critically regulates sperm capacitation and male fertility","volume":"3","author":"Zhou","year":"2008","journal-title":"PLoS One"},{"key":"10.1074\/jbc.M112.445866_bib47","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0003-9861(02)00278-3","article-title":"Assessment of acrosomal status in rat spermatozoa. Studies on carbohydrate and non-carbohydrate agonists","volume":"404","author":"Bendahmane","year":"2002","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M112.445866_bib48","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0890-6238(99)00062-3","article-title":"In vitro fertilization after in vivo treatment of rats with three reproductive toxicants","volume":"14","author":"Berger","year":"2000","journal-title":"Reprod. Toxicol."},{"key":"10.1074\/jbc.M112.445866_bib49","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/j.gastro.2005.05.057","article-title":"Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal type 3-deficient mice","volume":"129","author":"Ohmuraya","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1074\/jbc.M112.445866_bib50","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1093\/hmg\/ddi030","article-title":"Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome","volume":"14","author":"Hewett","year":"2005","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M112.445866_bib51","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1530\/jrf.0.0910292","article-title":"Testosterone and corticosterone co-regulate messenger RNA coding for secretory proteins in the epididymis of the lizard (Lacerta vivipara)","volume":"91","author":"Courty","year":"1991","journal-title":"J. Reprod. Fertil."},{"key":"10.1074\/jbc.M112.445866_bib52","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1016\/S0015-0282(16)55327-8","article-title":"The culture of human epididymal epithelium and in vitro maturation of epididymal spermatozoa","volume":"58","author":"Moore","year":"1992","journal-title":"Fertil. Steril."},{"key":"10.1074\/jbc.M112.445866_bib53","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1210\/me.2010-0226","article-title":"Research resource. Genome-wide mapping of in vivo androgen receptor binding sites in mouse epididymis","volume":"24","author":"Hu","year":"2010","journal-title":"Mol. Endocrinol."},{"key":"10.1074\/jbc.M112.445866_bib54","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.acthis.2006.10.002","article-title":"Dual localization. Proteins in extracellular and intracellular compartments","volume":"109","author":"Arnoys","year":"2007","journal-title":"Acta Histochem."},{"key":"10.1074\/jbc.M112.445866_bib55","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1093\/molehr\/7.7.617","article-title":"Changes of the major sperm maturation-associated epididymal protein HE5 (CD52) on human ejaculated spermatozoa during incubation","volume":"7","author":"Yeung","year":"2001","journal-title":"Mol. Hum. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib56","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1095\/biolreprod.105.048587","article-title":"Epididymal SPAM1 is a marker for sperm maturation in the mouse","volume":"74","author":"Chen","year":"2006","journal-title":"Biol. Reprod."},{"key":"10.1074\/jbc.M112.445866_bib57","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.mce.2005.12.033","article-title":"Epididymal SPAM1 and its impact on sperm function","volume":"250","author":"Martin-DeLeon","year":"2006","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1074\/jbc.M112.445866_bib58","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/(SICI)1098-2795(199902)52:2<225::AID-MRD14>3.0.CO;2-M","article-title":"Hamster sperm antigen P26h is a phosphatidylinositol-anchored protein","volume":"52","author":"L\u00e9gar\u00e9","year":"1999","journal-title":"Mol. Reprod. Dev."},{"key":"10.1074\/jbc.M112.445866_bib59","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/mrd.1013","article-title":"Prostasome-like particles are involved in the transfer of P25b from the bovine epididymal fluid to the sperm surface","volume":"59","author":"Frenette","year":"2001","journal-title":"Mol. Reprod. Dev."},{"key":"10.1074\/jbc.M112.445866_bib60","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1365-2605.2011.01159.x","article-title":"The mode of reproductive-derived Spink (serine protease inhibitor Kazal-type) action in the modulation of mammalian sperm activity","volume":"35","author":"Ou","year":"2012","journal-title":"Int. J. Androl."},{"key":"10.1074\/jbc.M112.445866_bib61","doi-asserted-by":"crossref","first-page":"4892","DOI":"10.1073\/pnas.1018202108","article-title":"Most fertilizing mouse spermatozoa begin their acrosome reaction before contact with the zona pellucida during in vitro fertilization","volume":"108","author":"Jin","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M112.445866_bib62","doi-asserted-by":"crossref","first-page":"20008","DOI":"10.1073\/pnas.1116965108","article-title":"Acrosome-reacted mouse spermatozoa recovered from the perivitelline space can fertilize other eggs","volume":"108","author":"Inoue","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1074\/jbc.M112.445866_bib63","doi-asserted-by":"crossref","first-page":"46981","DOI":"10.1074\/jbc.M403299200","article-title":"Mouse DESC1 is located within a cluster of seven DESC1-like genes and encodes a type II transmembrane serine protease that forms serpin inhibitory complexes","volume":"279","author":"Hobson","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M112.445866_bib64","first-page":"78","article-title":"Cloning, expression analysis, and tissue distribution of esp-1\/testisin, a membrane-type serine protease from the rat","volume":"50","author":"Nakamura","year":"2003","journal-title":"J. Med. Invest"},{"key":"10.1074\/jbc.M112.445866_bib65","doi-asserted-by":"crossref","first-page":"16976","DOI":"10.1074\/jbc.M112470200","article-title":"A mouse serine protease TESP5 is selectively included into lipid rafts of sperm membrane presumably as a glycosylphosphatidylinositol-anchored protein","volume":"277","author":"Honda","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M112.445866_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/mrd.20184","article-title":"TESSP-1. A novel serine protease gene expressed in the spermatogonia and spermatocytes of adult mouse testes","volume":"70","author":"Takano","year":"2005","journal-title":"Mol. Reprod. Dev."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820673793?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820673793?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M112.445866","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,27]],"date-time":"2021-06-27T06:11:18Z","timestamp":1624774278000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820673793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":66,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0021925820673793"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m112.445866","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}