{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:14:17Z","timestamp":1791173657669,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"30","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T00:00:00Z","timestamp":1599436800000},"content-version":"vor","delay-in-days":2625,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1074\/jbc.m113.465120","type":"journal-article","created":{"date-parts":[[2013,6,18]],"date-time":"2013-06-18T03:04:55Z","timestamp":1371524695000},"page":"21526-21536","source":"Crossref","is-referenced-by-count":21,"title":["Increased cAMP in Monocytes Augments Notch Signaling Mechanisms by Elevating RBP-J and Transducin-like Enhancer of Split (TLE)"],"prefix":"10.1016","volume":"288","author":[{"given":"Jason L.","family":"Larabee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salika M.","family":"Shakir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumitra","family":"Barua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jimmy D.","family":"Ballard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M113.465120_bib1","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/nrmicro2688","article-title":"The myriad roles of cyclic AMP in microbial pathogens. From signal to sword","volume":"10","author":"McDonough","year":"2012","journal-title":"Nat. Rev. Microbiol"},{"key":"10.1074\/jbc.M113.465120_bib2","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1073\/pnas.79.10.3162","article-title":"Anthrax toxin edema factor. A bacterial adenylate cyclase that increases cyclic AMP concentrations of eukaryotic cells","volume":"79","author":"Leppla","year":"1982","journal-title":"Proc. Natl. Acad. Sci"},{"key":"10.1074\/jbc.M113.465120_bib3","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1146\/annurev.biochem.75.103004.142728","article-title":"Anthrax toxin. Receptor binding, internalization, pore formation, and translocation","volume":"76","author":"Young","year":"2007","journal-title":"Annu. Rev. Biochem"},{"key":"10.1074\/jbc.M113.465120_bib4","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.chom.2010.10.004","article-title":"Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice","volume":"8","author":"Liu","year":"2010","journal-title":"Cell Host Microbe"},{"key":"10.1074\/jbc.M113.465120_bib5","doi-asserted-by":"crossref","first-page":"6150","DOI":"10.1073\/pnas.0800105105","article-title":"Antiinflammatory cAMP signaling and cell migration genes co-opted by the anthrax bacillus","volume":"105","author":"Kim","year":"2008","journal-title":"Proc. Natl. Acad. Sci"},{"key":"10.1074\/jbc.M113.465120_bib6","doi-asserted-by":"crossref","first-page":"19364","DOI":"10.1074\/jbc.M111.224543","article-title":"Adenomatous polyposis coli protein associates with C\/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages","volume":"286","author":"Larabee","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.465120_bib7","doi-asserted-by":"crossref","first-page":"3302","DOI":"10.1128\/IAI.05070-11","article-title":"Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophages","volume":"79","author":"Larabee","year":"2011","journal-title":"Infect. Immun"},{"key":"10.1074\/jbc.M113.465120_bib8","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1038\/nature09446","article-title":"Anthrax toxins cooperatively inhibit endocytic recycling by the Rab11\/Sec15 exocyst","volume":"467","author":"Guichard","year":"2010","journal-title":"Nature"},{"key":"10.1074\/jbc.M113.465120_bib9","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S1074-7613(03)00325-X","article-title":"Notch and the immune system","volume":"19","author":"Maillard","year":"2003","journal-title":"Immunity"},{"key":"10.1074\/jbc.M113.465120_bib10","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/jbiol145","article-title":"Notch signaling, the segmentation clock, and the patterning of vertebrate somites","volume":"8","author":"Lewis","year":"2009","journal-title":"J. Biol"},{"key":"10.1074\/jbc.M113.465120_bib11","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/nrm2009","article-title":"Notch signalling. A simple pathway becomes complex","volume":"7","author":"Bray","year":"2006","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"10.1074\/jbc.M113.465120_bib12","doi-asserted-by":"crossref","first-page":"4583","DOI":"10.1093\/nar\/gkm477","article-title":"Delta, Notch, and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors","volume":"35","author":"Fischer","year":"2007","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M113.465120_bib13","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.immuni.2008.08.016","article-title":"Integrated regulation of Toll-like receptor responses by Notch and interferon-\u03b3 pathways","volume":"29","author":"Hu","year":"2008","journal-title":"Immunity"},{"key":"10.1074\/jbc.M113.465120_bib14","doi-asserted-by":"crossref","first-page":"5023","DOI":"10.4049\/jimmunol.1001544","article-title":"Autoamplification of Notch signaling in macrophages by TLR-induced and RBP-J-dependent induction of Jagged1","volume":"185","author":"Foldi","year":"2010","journal-title":"J. Immunol"},{"key":"10.1074\/jbc.M113.465120_bib15","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/ni.2304","article-title":"Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization","volume":"13","author":"Xu","year":"2012","journal-title":"Nat. Immunol"},{"key":"10.1074\/jbc.M113.465120_bib16","doi-asserted-by":"crossref","first-page":"6208","DOI":"10.1074\/jbc.M111.310375","article-title":"Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1\/2-mediated nuclear factor \u03baB activation","volume":"287","author":"Zhang","year":"2012","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.465120_bib17","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/eji.200636999","article-title":"Notch signaling is activated by TLR stimulation and regulates macrophage functions","volume":"38","author":"Palaga","year":"2008","journal-title":"Eur. J. Immunol"},{"key":"10.1074\/jbc.M113.465120_bib18","doi-asserted-by":"crossref","first-page":"e6529","DOI":"10.1371\/journal.pone.0006529","article-title":"A versatile viral system for expression and depletion of proteins in mammalian cells","volume":"4","author":"Campeau","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.M113.465120_bib19","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1006\/bbrc.1996.0959","article-title":"Molecular interaction between TLE1 and the carboxyl-terminal domain of HES-1 containing the WRPW motif","volume":"223","author":"Grbavec","year":"1996","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"10.1074\/jbc.M113.465120_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1119(00)00161-X","article-title":"Groucho\/TLE family proteins and transcriptional repression","volume":"249","author":"Chen","year":"2000","journal-title":"Gene"},{"key":"10.1074\/jbc.M113.465120_bib21","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1046\/j.1432-1327.1998.2580339.x","article-title":"Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy\/Enhancer of split proteins, and is expressed during neuronal development","volume":"258","author":"Grbavec","year":"1998","journal-title":"Eur. J. Biochem"},{"key":"10.1074\/jbc.M113.465120_bib22","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1084\/jem.20051725","article-title":"Twist mediates suppression of inflammation by type I IFNs and Axl","volume":"203","author":"Sharif","year":"2006","journal-title":"J. Exp. Med"},{"key":"10.1074\/jbc.M113.465120_bib23","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0092-8674(03)00002-3","article-title":"Twist regulates cytokine gene expression through a negative feedback loop that represses NF-\u03baB activity","volume":"112","author":"\u0160o\u0161i","year":"2003","journal-title":"Cell"},{"key":"10.1074\/jbc.M113.465120_bib24","doi-asserted-by":"crossref","first-page":"pe37","DOI":"10.1126\/scisignal.275pe37","article-title":"Putting on the Brakes. Cyclic AMP as a multipronged controller of macrophage function","volume":"2","author":"Peters-Golden","year":"2009","journal-title":"Sci. Signal"},{"key":"10.1074\/jbc.M113.465120_bib25","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1165\/rcmb.2008-0091TR","article-title":"Cyclic AMP. Master regulator of innate immune cell function","volume":"39","author":"Serezani","year":"2008","journal-title":"Am. J. Respir. Cell Mol. Biol"},{"key":"10.1074\/jbc.M113.465120_bib26","doi-asserted-by":"crossref","first-page":"4383","DOI":"10.1074\/jbc.275.6.4383","article-title":"Inhibition of nuclear factor-\u03baB-mediated Transcription by association with the amino-terminal enhancer of Split, a Groucho-related protein lacking WD40 repeats","volume":"275","author":"Tetsuka","year":"2000","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.465120_bib27","doi-asserted-by":"crossref","first-page":"16583","DOI":"10.1074\/jbc.M111.222158","article-title":"Notch- and transducin-like enhancer of split (TLE)-dependent histone deacetylation explain interleukin 12 (IL-12) p70 inhibition by zymosan","volume":"286","author":"Alvarez","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.465120_bib28","doi-asserted-by":"crossref","first-page":"40681","DOI":"10.1074\/jbc.M110.176065","article-title":"Feed-forward signaling by membrane-bound ligand receptor circuit. The case of Notch Delta-like 4 ligand in endothelial cells","volume":"285","author":"Caolo","year":"2010","journal-title":"J. Biol. Chem"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820454547?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820454547?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M113.465120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T14:28:03Z","timestamp":1641306483000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820454547"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":28,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["S0021925820454547"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m113.465120","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}