{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T18:23:06Z","timestamp":1745605386509},"reference-count":55,"publisher":"Elsevier BV","issue":"23","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,11]],"date-time":"2020-09-11T00:00:00Z","timestamp":1599782400000},"content-version":"vor","delay-in-days":2659,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1074\/jbc.m113.470799","type":"journal-article","created":{"date-parts":[[2013,4,24]],"date-time":"2013-04-24T03:55:41Z","timestamp":1366775741000},"page":"16960-16974","source":"Crossref","is-referenced-by-count":18,"title":["NHERF2 Protein Mobility Rate Is Determined by a Unique C-terminal Domain That Is Also Necessary for Its Regulation of NHE3 Protein in OK Cells"],"prefix":"10.1016","volume":"288","author":[{"given":"Jianbo","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varsha","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boyoung","family":"Cha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tian-E","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafiquel","family":"Sarker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakhilya","family":"Murtazina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas C.","family":"Zachos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George H.","family":"Patterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Ming","family":"Tse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Kovbasnjuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuhang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Donowitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M113.470799_bib1","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1002\/jcp.22302","article-title":"Fundamental role of microvilli in the main functions of differentiated cells: Outline of an universal regulating and signaling system at the cell periphery","volume":"226","author":"Lange","year":"2011","journal-title":"J. Cell. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib2","doi-asserted-by":"crossref","first-page":"C198","DOI":"10.1152\/ajpcell.1995.269.1.C198","article-title":"Cloning, tissue distribution, and functional analysis of the human Na+\/N+ exchanger isoform, NHE3","volume":"269","author":"Brant","year":"1995","journal-title":"Am. J. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib3","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/969","article-title":"Renal and intestinal absorptive defects in mice lacking the NHE3 Na+\/H+ exchanger","volume":"19","author":"Schultheis","year":"1998","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M113.470799_bib4","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1152\/physrev.00030.2006","article-title":"Regulatory binding partners and complexes of NHE3","volume":"87","author":"Donowitz","year":"2007","journal-title":"Physiol. Rev"},{"key":"10.1074\/jbc.M113.470799_bib5","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1124\/pr.110.004176","article-title":"Regulation of G protein-coupled receptor function by Na+\/H+ exchange regulatory factors","volume":"63","author":"Ardura","year":"2011","journal-title":"Pharmacol. Rev"},{"key":"10.1074\/jbc.M113.470799_bib6","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/B978-0-12-385952-5.00003-8","article-title":"Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity","volume":"62","author":"Romero","year":"2011","journal-title":"Adv. Pharmacol"},{"key":"10.1074\/jbc.M113.470799_bib7","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1172\/JCI117903","article-title":"Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na+-H+ exchanger","volume":"95","author":"Weinman","year":"1995","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.M113.470799_bib8","doi-asserted-by":"crossref","first-page":"C771","DOI":"10.1152\/ajpcell.00119.2010","article-title":"NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity","volume":"300","author":"Sarker","year":"2011","journal-title":"Am. J. Physiol. Cell Physiol"},{"key":"10.1074\/jbc.M113.470799_bib9","doi-asserted-by":"crossref","first-page":"C126","DOI":"10.1152\/ajpcell.00311.2010","article-title":"NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum","volume":"301","author":"Murtazina","year":"2011","journal-title":"Am. J. Physiol. Cell Physiol"},{"key":"10.1074\/jbc.M113.470799_bib10","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1053\/j.gastro.2009.09.055","article-title":"Lysophosphatidic acid stimulates the intestinal brush border Na+\/H+ exchanger 3 and fluid absorption via LPA(5) and NHERF2","volume":"138","author":"Lin","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1074\/jbc.M113.470799_bib11","doi-asserted-by":"crossref","first-page":"7676","DOI":"10.1074\/jbc.M107768200","article-title":"Glucocorticoid activation of Na+\/H+ exchanger isoform 3 revisited. The roles of SGK1 and NHERF2","volume":"277","author":"Yun","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib12","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1113\/jphysiol.2007.131722","article-title":"NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes","volume":"581","author":"Cinar","year":"2007","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib13","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1159\/000185553","article-title":"Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4)-dependent mechanism","volume":"22","author":"Zachos","year":"2008","journal-title":"Cell. Physiol. Biochem"},{"key":"10.1074\/jbc.M113.470799_bib14","doi-asserted-by":"crossref","first-page":"C1494","DOI":"10.1152\/ajpcell.00092.2003","article-title":"Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse","volume":"285","author":"Wade","year":"2003","journal-title":"Am. J. Physiol. Cell Physiol"},{"key":"10.1074\/jbc.M113.470799_bib15","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/mrd.21122","article-title":"Organic cation\/carnitine transporter, OCTN2, transcriptional activity is regulated by osmotic stress in epididymal cells","volume":"77","author":"Cotton","year":"2010","journal-title":"Mol. Reprod. Dev"},{"key":"10.1074\/jbc.M113.470799_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1113\/jphysiol.2005.090399","article-title":"NHERF family and NHE3 regulation","volume":"567","author":"Donowitz","year":"2005","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib17","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1242\/jcs.056713","article-title":"NHE3 mobility in brush borders increases upon NHERF2-dependent stimulation by lysophosphatidic acid","volume":"123","author":"Cha","year":"2010","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.M113.470799_bib18","doi-asserted-by":"crossref","first-page":"e9406","DOI":"10.1371\/journal.pone.0009406","article-title":"Molecular model of the microvillar cytoskeleton and organization of the brush border","volume":"5","author":"Brown","year":"2010","journal-title":"PLoS One"},{"key":"10.1074\/jbc.M113.470799_bib19","doi-asserted-by":"crossref","first-page":"3353","DOI":"10.1242\/jcs.01180","article-title":"The lateral mobility of NHE3 on the apical membrane of renal epithelial OK cells is limited by the PDZ domain proteins NHERF1\/2, but is dependent on an intact actin cytoskeleton as determined by FRAP","volume":"117","author":"Cha","year":"2004","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.M113.470799_bib20","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1053\/j.gastro.2010.10.042","article-title":"d-Glucose acts via sodium\/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+\/H+ exchange regulatory factor 2-dependent process","volume":"140","author":"Lin","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1074\/jbc.M113.470799_bib21","doi-asserted-by":"crossref","first-page":"34486","DOI":"10.1074\/jbc.M111.230219","article-title":"Elevated calcium acutely regulates dynamic interactions of NHERF2 and NHE3 in OK cell microvilli","volume":"286","author":"Zhu","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib22","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1749-6632.2009.04046.x","article-title":"The role of the NHERF family of PDZ scaffolding proteins in the regulation of salt and water transport","volume":"1165","author":"Seidler","year":"2009","journal-title":"Ann. N.Y. Acad. Sci"},{"key":"10.1074\/jbc.M113.470799_bib23","doi-asserted-by":"crossref","first-page":"25856","DOI":"10.1074\/jbc.273.40.25856","article-title":"NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+\/H+ exchanger NHE3 and the cytoskeletal protein ezrin","volume":"273","author":"Yun","year":"1998","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib24","doi-asserted-by":"crossref","first-page":"17845","DOI":"10.1074\/jbc.M601740200","article-title":"Na+\/H+ exchanger NHE3 activity and trafficking are lipid Raft-dependent","volume":"281","author":"Murtazina","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib25","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1038\/nmeth.1296","article-title":"A bright and photostable photoconvertible fluorescent protein","volume":"6","author":"McKinney","year":"2009","journal-title":"Nat. Methods"},{"key":"10.1074\/jbc.M113.470799_bib26","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1083\/jcb.138.6.1193","article-title":"Nuclear membrane dynamics and reassembly in living cells: targeting of an inner nuclear membrane protein in interphase and mitosis","volume":"138","author":"Ellenberg","year":"1997","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M113.470799_bib27","doi-asserted-by":"crossref","DOI":"10.1002\/0471143030.cb0418s39","article-title":"Fluorescence imaging techniques for studying Drosophila embryo development","author":"Mavrakis","year":"2008","journal-title":"Curr. Protoc. Cell Biol"},{"key":"10.1074\/jbc.M113.470799_bib28","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1111\/j.1469-7793.2001.00537.x","article-title":"Na+-H+ exchanger 3 (NHE3) is present in lipid rafts in the rabbit ileal brush border: a role for rafts in trafficking and rapid stimulation of NHE3","volume":"537","author":"Li","year":"2001","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib29","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1113\/jphysiol.2004.060921","article-title":"Carbachol regulation of rabbit ileal brush border Na+-H+ exchanger 3 (NHE3) occurs through changes in NHE3 trafficking and complex formation and is Src-dependent","volume":"556","author":"Li","year":"2004","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib30","doi-asserted-by":"crossref","first-page":"5494","DOI":"10.1074\/jbc.M312445200","article-title":"Increased diffusional mobility of CFTR at the plasma membrane after deletion of its C-terminal PDZ-binding motif","volume":"279","author":"Haggie","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib31","doi-asserted-by":"crossref","first-page":"35020","DOI":"10.1074\/jbc.M111.264978","article-title":"Dynamic Na+-H+ exchanger regulatory factor-1 association and dissociation regulate parathyroid hormone receptor trafficking at membrane microdomains","volume":"286","author":"Ardura","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib32","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1083\/jcb.201204008","article-title":"PDZ interactions regulate rapid turnover of the scaffolding protein EBP50 in microvilli","volume":"198","author":"Garbett","year":"2012","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M113.470799_bib33","first-page":"F672","article-title":"Clonal sublines that are morphologically and functionally distinct from parental OK cells","volume":"256","author":"Cole","year":"1989","journal-title":"Am. J. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib34","doi-asserted-by":"crossref","first-page":"31704","DOI":"10.1074\/jbc.M110.164137","article-title":"Apical scaffolding protein NHERF2 modulates the localization of alternatively spliced plasma membrane Ca2+ pump 2B variants in polarized epithelial cells","volume":"285","author":"Pad\u00e1nyi","year":"2010","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib35","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1478-811X-8-8","article-title":"PDZ domains and their binding partners: structure, specificity, and modification","volume":"8","author":"Lee","year":"2010","journal-title":"Cell Commun. Signal"},{"key":"10.1074\/jbc.M113.470799_bib36","doi-asserted-by":"crossref","first-page":"18973","DOI":"10.1074\/jbc.M201507200","article-title":"Structural determinants of the Na+\/H+ exchanger regulatory factor interaction with the \u03b22 adrenergic and platelet-derived growth factor receptors","volume":"277","author":"Karthikeyan","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib37","doi-asserted-by":"crossref","first-page":"12662","DOI":"10.1021\/bi035244l","article-title":"A C-terminal PDZ motif in NHE3 binds NHERF-1 and enhances cAMP inhibition of sodium-hydrogen exchange","volume":"42","author":"Weinman","year":"2003","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M113.470799_bib38","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1242\/jcs.01038","article-title":"The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain","volume":"117","author":"Finnerty","year":"2004","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.M113.470799_bib39","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.str.2006.01.015","article-title":"Structural basis for NHERF recognition by ERM proteins","volume":"14","author":"Terawaki","year":"2006","journal-title":"Structure"},{"key":"10.1074\/jbc.M113.470799_bib40","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1128\/MCB.01372-06","article-title":"NHERF1\/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands","volume":"27","author":"Morales","year":"2007","journal-title":"Mol. Cell. Biol"},{"key":"10.1074\/jbc.M113.470799_bib41","doi-asserted-by":"crossref","first-page":"F374","DOI":"10.1152\/ajprenal.2001.281.2.F374","article-title":"Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na+\/H+ exchange in OK cells","volume":"281","author":"Weinman","year":"2001","journal-title":"Am. J. Physiol. Renal Physiol"},{"key":"10.1074\/jbc.M113.470799_bib42","doi-asserted-by":"crossref","first-page":"541","DOI":"10.4049\/jimmunol.168.2.541","article-title":"Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly","volume":"168","author":"Itoh","year":"2002","journal-title":"J. Immunol"},{"key":"10.1074\/jbc.M113.470799_bib43","doi-asserted-by":"crossref","first-page":"G907","DOI":"10.1152\/ajpgi.00191.2010","article-title":"Activity and PI3-kinase-dependent trafficking of the intestinal anion exchanger down-regulated in adenoma depend on its PDZ interaction and on lipid rafts","volume":"299","author":"Lissner","year":"2010","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"10.1074\/jbc.M113.470799_bib44","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1083\/jcb.131.5.1231","article-title":"Ezrin oligomers are major cytoskeletal components of placental microvilli: a proposal for their involvement in cortical morphogenesis","volume":"131","author":"Berryman","year":"1995","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M113.470799_bib45","doi-asserted-by":"crossref","first-page":"16494","DOI":"10.1074\/jbc.M300580200","article-title":"Lysophosphatidic acid stimulates brush border Na+\/H+ exchanger 3 (NHE3) activity by increasing its exocytosis by an NHE3 kinase A regulatory protein-dependent mechanism","volume":"278","author":"Lee-Kwon","year":"2003","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib46","doi-asserted-by":"crossref","first-page":"C1527","DOI":"10.1152\/ajpcell.00017.2003","article-title":"Ca2+-dependent inhibition of NHE3 requires PKC\u03b1, which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes","volume":"285","author":"Lee-Kwon","year":"2003","journal-title":"Am. J. Physiol. Cell Physiol"},{"key":"10.1074\/jbc.M113.470799_bib47","doi-asserted-by":"crossref","first-page":"12813","DOI":"10.1073\/pnas.192084599","article-title":"Molecular analysis of microscopic ezrin dynamics by two-photon FRAP","volume":"99","author":"Coscoy","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M113.470799_bib48","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1529\/biophysj.104.049619","article-title":"A two-photon FRAP analysis of the cytoskeleton dynamics in the microvilli of intestinal cells","volume":"88","author":"Waharte","year":"2005","journal-title":"Biophys. J"},{"key":"10.1074\/jbc.M113.470799_bib49","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1016\/S0006-3495(02)75537-9","article-title":"MYO1A (brush border myosin I) dynamics in the brush border of LLC-PK1-CL4 cells","volume":"82","author":"Tyska","year":"2002","journal-title":"Biophys. J"},{"key":"10.1074\/jbc.M113.470799_bib50","doi-asserted-by":"crossref","first-page":"F1560","DOI":"10.1152\/ajprenal.90657.2008","article-title":"PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP","volume":"297","author":"Weinman","year":"2009","journal-title":"Am. J. Physiol. Renal Physiol"},{"key":"10.1074\/jbc.M113.470799_bib51","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1091\/mbc.e05-09-0843","article-title":"The NHE3 juxtamembrane cytoplasmic domain directly binds ezrin: dual role in NHE3 trafficking and mobility in the brush border","volume":"17","author":"Cha","year":"2006","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M113.470799_bib52","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1074\/jbc.M509786200","article-title":"Shank2 associates with and regulates Na+\/H+ exchanger 3","volume":"281","author":"Han","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib53","doi-asserted-by":"crossref","first-page":"23714","DOI":"10.1074\/jbc.M200835200","article-title":"Ca2+-dependent inhibition of Na+\/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-\u03b1-actinin-4 complex for oligomerization and endocytosis","volume":"277","author":"Kim","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.470799_bib54","doi-asserted-by":"crossref","first-page":"5049","DOI":"10.1113\/jphysiol.2010.198721","article-title":"Loss of PDZ-adaptor protein NHERF2 affects membrane localization and cGMP- and [Ca2+]- but not cAMP-dependent regulation of Na+\/H+ exchanger 3 in murine intestine","volume":"588","author":"Chen","year":"2010","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M113.470799_bib55","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1091\/mbc.e10-01-0008","article-title":"A regulated complex of the scaffolding proteins PDZK1 and EBP50 with ezrin contribute to microvillar organization","volume":"21","author":"LaLonde","year":"2010","journal-title":"Mol. Biol. Cell"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820537010?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820537010?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M113.470799","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T00:33:16Z","timestamp":1641342796000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820537010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":55,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S0021925820537010"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m113.470799","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}