{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:48:01Z","timestamp":1792100881446,"version":"4.4.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"43","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T00:00:00Z","timestamp":1599868800000},"content-version":"vor","delay-in-days":2538,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1074\/jbc.m113.486589","type":"journal-article","created":{"date-parts":[[2013,9,11]],"date-time":"2013-09-11T20:33:46Z","timestamp":1378931626000},"page":"31127-31138","source":"Crossref","is-referenced-by-count":54,"title":["Toxoplasma Transcription Factor TgAP2XI-5 Regulates the Expression of Genes Involved in Parasite Virulence and Host Invasion"],"prefix":"10.1016","volume":"288","author":[{"given":"Robert","family":"Walker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Gissot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludovic","family":"Huot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tchilabalo Dilezitoko","family":"Alayi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillemette","family":"Marot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Schaeffer-Reiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Van Dorsselaer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kami","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislas","family":"Tomavo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M113.486589_bib1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1741-7007-3-26","article-title":"The transcriptome of Toxoplasma gondii","volume":"3","author":"Radke","year":"2005","journal-title":"BMC Biol"},{"key":"10.1074\/jbc.M113.486589_bib2","doi-asserted-by":"crossref","first-page":"e12354","DOI":"10.1371\/journal.pone.0012354","article-title":"Coordinated progression through two subtranscriptomes underlies the tachyzoite cycle of Toxoplasma gondii","volume":"5","author":"Behnke","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.M113.486589_bib3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.ijpara.2008.10.002","article-title":"New eukaryotic systematics. A phylogenetic perspective of developmental gene expression in the Apicomplexa","volume":"39","author":"Gissot","year":"2009","journal-title":"Int. J. Parasitol"},{"key":"10.1074\/jbc.M113.486589_bib4","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1371\/journal.ppat.0030077","article-title":"Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii","volume":"3","author":"Gissot","year":"2007","journal-title":"PLoS Pathog"},{"key":"10.1074\/jbc.M113.486589_bib5","doi-asserted-by":"crossref","first-page":"e1001232","DOI":"10.1371\/journal.ppat.1001232","article-title":"Toxoplasma gondii lysine acetyltransferase GCN5-A functions in the cellular response to alkaline stress and expression of cyst genes","volume":"6","author":"Naguleswaran","year":"2010","journal-title":"PLoS Pathog"},{"key":"10.1074\/jbc.M113.486589_bib6","doi-asserted-by":"crossref","first-page":"3994","DOI":"10.1093\/nar\/gki709","article-title":"Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains","volume":"33","author":"Balaji","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M113.486589_bib7","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/mmi.12121","article-title":"The Toxoplasma nuclear factor TgAP2XI-4 controls bradyzoite gene expression and cyst formation","volume":"87","author":"Walker","year":"2013","journal-title":"Mol. Microbiol"},{"key":"10.1074\/jbc.M113.486589_bib8","doi-asserted-by":"crossref","first-page":"6871","DOI":"10.1073\/pnas.1300059110","article-title":"ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst","volume":"110","author":"Radke","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M113.486589_bib9","doi-asserted-by":"crossref","first-page":"e1001165","DOI":"10.1371\/journal.ppat.1001165","article-title":"Identification and genome-wide prediction of DNA binding specificities for the ApiAP2 family of regulators from the malaria parasite","volume":"6","author":"Campbell","year":"2010","journal-title":"PLoS Pathog"},{"key":"10.1074\/jbc.M113.486589_bib10","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1111\/j.1365-2958.2009.06609.x","article-title":"Identification of a transcription factor in the mosquito-invasive stage of malaria parasites","volume":"71","author":"Yuda","year":"2009","journal-title":"Mol. Microbiol"},{"key":"10.1074\/jbc.M113.486589_bib11","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1111\/j.1365-2958.2009.07005.x","article-title":"Transcription factor AP2-Sp and its target genes in malarial sporozoites","volume":"75","author":"Yuda","year":"2010","journal-title":"Mol. Microbiol"},{"key":"10.1074\/jbc.M113.486589_bib12","doi-asserted-by":"crossref","first-page":"e47557","DOI":"10.1371\/journal.pone.0047557","article-title":"Identification of an AP2-family protein that is critical for malaria liver stage development","volume":"7","author":"Iwanaga","year":"2012","journal-title":"PLoS One"},{"key":"10.1074\/jbc.M113.486589_bib13","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1128\/EC.00358-08","article-title":"Tagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80","volume":"8","author":"Huynh","year":"2009","journal-title":"Eukaryot. Cell"},{"key":"10.1074\/jbc.M113.486589_bib14","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1128\/EC.00073-08","article-title":"Expression quantitative trait locus mapping of Toxoplasma genes reveals multiple mechanisms for strain-specific differences in gene expression","volume":"7","author":"Boyle","year":"2008","journal-title":"Eukaryot. Cell"},{"key":"10.1074\/jbc.M113.486589_bib15","doi-asserted-by":"crossref","first-page":"e32671","DOI":"10.1371\/journal.pone.0032671","article-title":"Toxoplasma gondii chromodomain protein 1 binds to heterochromatin and colocalises with centromeres and telomeres at the nuclear periphery","volume":"7","author":"Gissot","year":"2012","journal-title":"PLoS One"},{"key":"10.1074\/jbc.M113.486589_bib16","doi-asserted-by":"crossref","first-page":"4878","DOI":"10.1093\/nar\/23.23.4878","article-title":"MatInd and MatInspector. New fast and versatile tools for detection of consensus matches in nucleotide sequence data","volume":"23","author":"Quandt","year":"1995","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M113.486589_bib17","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.chom.2012.10.016","article-title":"A tetracycline-repressible transactivator system to study essential genes in malaria parasites","volume":"12","author":"Pino","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1074\/jbc.M113.486589_bib18","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.jmb.2009.11.004","article-title":"Structural determinants of DNA binding by a P. falciparum ApiAP2 transcriptional regulator","volume":"395","author":"Lindner","year":"2010","journal-title":"J. Mol. Biol"},{"key":"10.1074\/jbc.M113.486589_bib19","doi-asserted-by":"crossref","first-page":"8393","DOI":"10.1073\/pnas.0801993105","article-title":"Specific DNA-binding by apicomplexan AP2 transcription factors","volume":"105","author":"De Silva","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M113.486589_bib20","doi-asserted-by":"crossref","first-page":"e1000227","DOI":"10.1371\/journal.pcbi.1000227","article-title":"Analyzing ChIP-chip data using bioconductor","volume":"4","author":"Toedling","year":"2008","journal-title":"PLoS Comput. Biol"},{"key":"10.1074\/jbc.M113.486589_bib21","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/nrm909","article-title":"Stats. Transcriptional control and biological impact","volume":"3","author":"Levy","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"10.1074\/jbc.M113.486589_bib22","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.chom.2011.09.004","article-title":"The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries","volume":"10","author":"Treeck","year":"2011","journal-title":"Cell Host Microbe"},{"key":"10.1074\/jbc.M113.486589_bib23","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.tibs.2008.02.002","article-title":"Choose your partners. Dimerization in eukaryotic transcription factors","volume":"33","author":"Amoutzias","year":"2008","journal-title":"Trends Biochem. Sci"},{"key":"10.1074\/jbc.M113.486589_bib24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/nature04104","article-title":"A protein interaction network of the malaria parasite Plasmodium falciparum","volume":"438","author":"LaCount","year":"2005","journal-title":"Nature"},{"key":"10.1074\/jbc.M113.486589_bib25","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1126\/science.1133690","article-title":"Polymorphic secreted kinases are key virulence factors in toxoplasmosis","volume":"314","author":"Saeij","year":"2006","journal-title":"Science"},{"key":"10.1074\/jbc.M113.486589_bib26","doi-asserted-by":"crossref","first-page":"10301","DOI":"10.1128\/MCB.25.23.10301-10314.2005","article-title":"Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii","volume":"25","author":"Saksouk","year":"2005","journal-title":"Mol. Cell. Biol"},{"key":"10.1074\/jbc.M113.486589_bib27","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1073\/pnas.88.9.3720","article-title":"Cross-family dimerization of transcription factors Fos\/Jun and ATF\/CREB alters DNA binding specificity","volume":"88","author":"Hai","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U.S.A"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820487137?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820487137?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M113.486589","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T16:07:28Z","timestamp":1649088448000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820487137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":27,"journal-issue":{"issue":"43","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0021925820487137"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m113.486589","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}