{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:32:44Z","timestamp":1791329564170,"version":"4.3.1"},"reference-count":59,"publisher":"Elsevier BV","issue":"48","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":2525,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1074\/jbc.m113.508812","type":"journal-article","created":{"date-parts":[[2013,10,5]],"date-time":"2013-10-05T02:37:37Z","timestamp":1380940657000},"page":"34414-34426","source":"Crossref","is-referenced-by-count":202,"title":["Differential Phospholipid Substrates and Directional Transport by ATP-binding Cassette Proteins ABCA1, ABCA7, and ABCA4 and Disease-causing Mutants"],"prefix":"10.1016","volume":"288","author":[{"given":"Faraz","family":"Quazi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert S.","family":"Molday","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M113.508812_bib1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev.cb.08.110192.000435","article-title":"ABC transporters: from microorganisms to man","volume":"8","author":"Higgins","year":"1992","journal-title":"Annu. Rev. Cell Biol"},{"key":"10.1074\/jbc.M113.508812_bib2","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1146\/annurev.genom.6.080604.162122","article-title":"Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates","volume":"6","author":"Dean","year":"2005","journal-title":"Annu. Rev. Genomics Hum. Genet"},{"key":"10.1074\/jbc.M113.508812_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3389\/fpsyt.2012.00017","article-title":"A-subclass ATP-binding cassette proteins in brain lipid homeostasis and neurodegeneration","volume":"3","author":"Piehler","year":"2012","journal-title":"Front. Psychiatry"},{"key":"10.1074\/jbc.M113.508812_bib4","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.bbalip.2012.10.006","article-title":"Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport","volume":"1831","author":"Coleman","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M113.508812_bib5","doi-asserted-by":"crossref","first-page":"23539","DOI":"10.1074\/jbc.M101902200","article-title":"Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: identification of N-linked glycosylation sites","volume":"276","author":"Bungert","year":"2001","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib6","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1042\/bse0500265","article-title":"Lipid transport by mammalian ABC proteins","volume":"50","author":"Quazi","year":"2011","journal-title":"Essays Biochem"},{"key":"10.1074\/jbc.M113.508812_bib7","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.2741\/2305","article-title":"ABC A-subclass proteins: gatekeepers of cellular phospho- and sphingolipid transport","volume":"12","author":"Wenzel","year":"2007","journal-title":"Front. Biosci"},{"key":"10.1074\/jbc.M113.508812_bib8","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1161\/01.RES.0000250171.54048.5c","article-title":"ATP-binding cassette cholesterol transporters and cardiovascular disease","volume":"99","author":"Oram","year":"2006","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M113.508812_bib9","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/11905","article-title":"Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency","volume":"22","author":"Brooks-Wilson","year":"1999","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M113.508812_bib10","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/11914","article-title":"The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease","volume":"22","author":"Bodzioch","year":"1999","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M113.508812_bib11","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/11921","article-title":"Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1","volume":"22","author":"Rust","year":"1999","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M113.508812_bib12","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1161\/01.ATV.0000078520.89539.77","article-title":"Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene","volume":"23","author":"Singaraja","year":"2003","journal-title":"Arterioscler. Thromb. Vasc. Biol"},{"key":"10.1074\/jbc.M113.508812_bib13","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1021\/bi035813p","article-title":"Cross-linking and lipid efflux properties of apoA-I mutants suggest direct association between apoA-I helices and ABCA1","volume":"43","author":"Chroni","year":"2004","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M113.508812_bib14","doi-asserted-by":"crossref","first-page":"33053","DOI":"10.1074\/jbc.M005438200","article-title":"Specific binding of ApoA-I, enhanced cholesterol efflux, and altered plasma membrane morphology in cells expressing ABC1","volume":"275","author":"Wang","year":"2000","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib15","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1194\/jlr.M300355-JLR200","article-title":"ABCA1 and amphipathic apolipoproteins form high-affinity molecular complexes required for cholesterol efflux","volume":"45","author":"Fitzgerald","year":"2004","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.M113.508812_bib16","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.bbalip.2011.06.024","article-title":"Lysine residues of ABCA1 are required for the interaction with apoA-I","volume":"1821","author":"Nagao","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M113.508812_bib17","doi-asserted-by":"crossref","first-page":"26321","DOI":"10.1074\/jbc.M413993200","article-title":"Headgroup-specific exposure of phospholipids in ABCA1-expressing cells","volume":"280","author":"Alder-Baerens","year":"2005","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib18","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1161\/01.RES.0000237920.70451.ad","article-title":"Specific mutations in ABCA1 have discrete effects on ABCA1 function and lipid phenotypes both in vivoin vitro","volume":"99","author":"Singaraja","year":"2006","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M113.508812_bib19","doi-asserted-by":"crossref","first-page":"33178","DOI":"10.1074\/jbc.M204996200","article-title":"Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I","volume":"277","author":"Fitzgerald","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib20","doi-asserted-by":"crossref","first-page":"8815","DOI":"10.1074\/jbc.M206885200","article-title":"Effects of mutations of ABCA1 in the first extracellular domain on subcellular trafficking and ATP binding\/hydrolysis","volume":"278","author":"Tanaka","year":"2003","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib21","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1073\/pnas.97.8.4245","article-title":"High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1","volume":"97","author":"McNeish","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M113.508812_bib22","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/01.wnr.0000221833.41340.cd","article-title":"Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells","volume":"17","author":"Kim","year":"2006","journal-title":"Neuroreport"},{"key":"10.1074\/jbc.M113.508812_bib23","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1016\/j.febslet.2005.12.029","article-title":"ABCA7, a molecule with unknown function","volume":"580","author":"Abe-Dohmae","year":"2006","journal-title":"FEBS Lett"},{"key":"10.1074\/jbc.M113.508812_bib24","doi-asserted-by":"crossref","first-page":"42906","DOI":"10.1074\/jbc.M307831200","article-title":"ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux","volume":"278","author":"Wang","year":"2003","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib25","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1194\/jlr.M400247-JLR200","article-title":"Potential role of ABCA7 in cellular lipid efflux to apoA-I","volume":"46","author":"Linsel-Nitschke","year":"2005","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.M113.508812_bib26","doi-asserted-by":"crossref","first-page":"10303","DOI":"10.1074\/jbc.272.15.10303","article-title":"The 220-kDa rim protein of retinal rod outer segments is a member of the ABC transporter superfamily","volume":"272","author":"Illing","year":"1997","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib27","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/ng0397-236","article-title":"A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy","volume":"15","author":"Allikmets","year":"1997","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M113.508812_bib28","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s004390050649","article-title":"Mapping of the rod photoreceptor ABC transporter (ABCR) to 1p21-p22.1 and identification of novel mutations in Stargardt's disease","volume":"102","author":"Nasonkin","year":"1998","journal-title":"Hum. Genet"},{"key":"10.1074\/jbc.M113.508812_bib29","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1038\/ncomms1927","article-title":"ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer","volume":"3","author":"Quazi","year":"2012","journal-title":"Nat. Commun"},{"key":"10.1074\/jbc.M113.508812_bib30","doi-asserted-by":"crossref","first-page":"53972","DOI":"10.1074\/jbc.M405216200","article-title":"N-Retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR)","volume":"279","author":"Beharry","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib31","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.bbalip.2009.02.004","article-title":"The role of the photoreceptor ABC transporter ABCA4 in lipid transport and Stargardt macular degeneration","volume":"1791","author":"Molday","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M113.508812_bib32","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0092-8674(00)80602-9","article-title":"Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice","volume":"98","author":"Weng","year":"1999","journal-title":"Cell"},{"key":"10.1074\/jbc.M113.508812_bib33","first-page":"1685","article-title":"Delayed dark-adaptation and lipofuscin accumulation in abcr+\/\u2212 mice: implications for involvement of ABCR in age-related macular degeneration","volume":"42","author":"Mata","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci"},{"key":"10.1074\/jbc.M113.508812_bib34","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.str.2013.03.001","article-title":"Molecular organization and ATP-induced conformational changes of ABCA4, the photoreceptor-specific ABC transporter","volume":"21","author":"Tsybovsky","year":"2013","journal-title":"Structure"},{"key":"10.1074\/jbc.M113.508812_bib35","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1074\/jbc.M309888200","article-title":"Human ABCA7 supports apolipoprotein-mediated release of cellular cholesterol and phospholipid to generate high density lipoprotein","volume":"279","author":"Abe-Dohmae","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib36","doi-asserted-by":"crossref","first-page":"6855","DOI":"10.1021\/bi200774w","article-title":"Posttranslational modifications of the photoreceptor-specific ABC transporter ABCA4","volume":"50","author":"Tsybovsky","year":"2011","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M113.508812_bib37","doi-asserted-by":"crossref","first-page":"39600","DOI":"10.1074\/jbc.M304236200","article-title":"Functional interaction between the two halves of the photoreceptor-specific ATP binding cassette protein ABCR (ABCA4). Evidence for a non-exchangeable ADP in the first nucleotide binding domain","volume":"278","author":"Ahn","year":"2003","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib38","doi-asserted-by":"crossref","first-page":"e28401","DOI":"10.1371\/journal.pone.0028401","article-title":"Flip-flop of phospholipids in proteoliposomes reconstituted from detergent extract of chloroplast membranes: kinetics and phospholipid specificity","volume":"6","author":"Rajasekharan","year":"2011","journal-title":"PLoS One"},{"key":"10.1074\/jbc.M113.508812_bib39","doi-asserted-by":"crossref","first-page":"20399","DOI":"10.1074\/jbc.M000555200","article-title":"The effect of lipid environment and retinoids on the ATPase activity of ABCR, the photoreceptor ABC transporter responsible for Stargardt macular dystrophy","volume":"275","author":"Ahn","year":"2000","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib40","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1111\/j.1365-2818.2006.01706.x","article-title":"A guided tour into subcellular colocalization analysis in light microscopy","volume":"224","author":"Bolte","year":"2006","journal-title":"J. Microsc"},{"key":"10.1074\/jbc.M113.508812_bib41","doi-asserted-by":"crossref","first-page":"3640","DOI":"10.1074\/jbc.M806580200","article-title":"Role of the C terminus of the photoreceptor ABCA4 transporter in protein folding, function, and retinal degenerative diseases","volume":"284","author":"Zhong","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib42","doi-asserted-by":"crossref","first-page":"6937","DOI":"10.1021\/bi0024456","article-title":"Phospholipid flippase activity of the reconstituted P-glycoprotein multidrug transporter","volume":"40","author":"Romsicki","year":"2001","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M113.508812_bib43","doi-asserted-by":"crossref","first-page":"32670","DOI":"10.1074\/jbc.M109.047415","article-title":"Localization, purification, and functional reconstitution of the P4-ATPase Atp8a2, a phosphatidylserine flippase in photoreceptor disc membranes","volume":"284","author":"Coleman","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib44","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0165-022X(80)90077-9","article-title":"Fluorescence spectroscopic investigations of the dynamic properties of proteins, membranes and nucleic acids","volume":"2","author":"Lakowicz","year":"1980","journal-title":"J. Biochem. Biophys. Methods"},{"key":"10.1074\/jbc.M113.508812_bib45","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1006\/bbrc.2001.5905","article-title":"Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter","volume":"288","author":"Szak\u00e1cs","year":"2001","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"10.1074\/jbc.M113.508812_bib46","doi-asserted-by":"crossref","first-page":"10760","DOI":"10.1074\/jbc.M513783200","article-title":"Purification and ATPase activity of human ABCA1","volume":"281","author":"Takahashi","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib47","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1006\/abbi.2001.2299","article-title":"Purification and characterization of N-glycosylation mutant mouse and human P-glycoproteins expressed in Pichia pastoris cells","volume":"388","author":"Urbatsch","year":"2001","journal-title":"Arch. Biochem. Biophys"},{"key":"10.1074\/jbc.M113.508812_bib48","doi-asserted-by":"crossref","first-page":"33740","DOI":"10.1074\/jbc.M109.047779","article-title":"Purification and reconstitution of the antigen transport complex TAP: a prerequisite for determination of peptide stoichiometry and ATP hydrolysis","volume":"284","author":"Herget","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib49","doi-asserted-by":"crossref","first-page":"23742","DOI":"10.1074\/jbc.M102348200","article-title":"ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein","volume":"276","author":"Wang","year":"2001","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib50","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1194\/jlr.M300336-JLR200","article-title":"ABCA1 mediates concurrent cholesterol and phospholipid efflux to apolipoprotein A-I","volume":"45","author":"Smith","year":"2004","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.M113.508812_bib51","doi-asserted-by":"crossref","first-page":"14113","DOI":"10.1021\/bi0004192","article-title":"A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-1","volume":"39","author":"Fielding","year":"2000","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M113.508812_bib52","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1194\/jlr.M700206-JLR200","article-title":"Identification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesis","volume":"48","author":"Hassan","year":"2007","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.M113.508812_bib53","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1194\/jlr.M016196","article-title":"Membrane microdomains modulate oligomeric ABCA1 function: impact on apoAI-mediated lipid removal and phosphatidylcholine biosynthesis","volume":"52","author":"Iatan","year":"2011","journal-title":"J. Lipid Res"},{"key":"10.1074\/jbc.M113.508812_bib54","doi-asserted-by":"crossref","first-page":"25123","DOI":"10.1074\/jbc.M704590200","article-title":"Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles","volume":"282","author":"Vedhachalam","year":"2007","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib55","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.1111\/j.1742-4658.2011.08170.x","article-title":"Function and regulation of ABCA1-membrane meso-domain organization and reorganization","volume":"278","author":"Nagao","year":"2011","journal-title":"FEBS J"},{"key":"10.1074\/jbc.M113.508812_bib56","doi-asserted-by":"crossref","first-page":"5034","DOI":"10.1073\/pnas.1220703110","article-title":"ABCA1 dimer-monomer interconversion during HDL generation revealed by single-molecule imaging","volume":"110","author":"Nagata","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M113.508812_bib57","doi-asserted-by":"crossref","first-page":"11293","DOI":"10.1074\/jbc.M900580200","article-title":"Formation of two intramolecular disulfide bonds is necessary for ApoA-I-dependent cholesterol efflux mediated by ABCA1","volume":"284","author":"Hozoji","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.508812_bib58","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1021\/pr801008c","article-title":"A carboxyl-terminal affinity tag for the purification and mass spectrometric characterization of integral membrane proteins","volume":"8","author":"Wong","year":"2009","journal-title":"J. Proteome Res"},{"key":"10.1074\/jbc.M113.508812_bib59","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.biochi.2012.11.009","article-title":"Cholesterol transport via ABCA1: new insights from solid-phase binding assay","volume":"95","author":"Reboul","year":"2013","journal-title":"Biochimie"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820554380?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820554380?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M113.508812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T02:23:56Z","timestamp":1639707836000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820554380"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":59,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0021925820554380"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m113.508812","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]}}}