{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T04:35:18Z","timestamp":1791779718648,"version":"4.3.4"},"reference-count":26,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,19]],"date-time":"2020-09-19T00:00:00Z","timestamp":1600473600000},"content-version":"vor","delay-in-days":2394,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01DK55615"],"award-info":[{"award-number":["R01DK55615"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1074\/jbc.m113.544064","type":"journal-article","created":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T20:44:23Z","timestamp":1389300263000},"page":"6751-6761","source":"Crossref","is-referenced-by-count":79,"title":["The Metabolic Origins of Mannose in Glycoproteins"],"prefix":"10.1016","volume":"289","author":[{"given":"Mie","family":"Ichikawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Estelle","family":"Losfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hudson H.","family":"Freeze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M113.544064_bib1","doi-asserted-by":"crossref","first-page":"39431","DOI":"10.1074\/jbc.M111.285502","article-title":"Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts","volume":"286","author":"Sharma","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.544064_bib2","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1172\/JCI118570","article-title":"Mannose corrects altered N-glycosylation in carbohydrate-deficient glycoprotein syndrome fibroblasts","volume":"97","author":"Panneerselvam","year":"1996","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.M113.544064_bib3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/nm.2548","article-title":"Successful prenatal mannose treatment for congenital disorder of glycosylation-Ia in mice","volume":"18","author":"Schneider","year":"2012","journal-title":"Nat. Med"},{"key":"10.1074\/jbc.M113.544064_bib4","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1172\/JCI2350","article-title":"Carbohydrate-deficient glycoprotein syndrome type Ib. Phosphomannose isomerase deficiency and mannose therapy","volume":"101","author":"Niehues","year":"1998","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.M113.544064_bib5","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1111\/j.1651-2227.2002.tb00101.x","article-title":"Oral mannose therapy persistently corrects the severe clinical symptoms and biochemical abnormalities of phosphomannose isomerase deficiency","volume":"91","author":"Harms","year":"2002","journal-title":"Acta Paediatr"},{"key":"10.1074\/jbc.M113.544064_bib6","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1111\/j.1651-2227.1998.tb01556.x","article-title":"Failure of short-term mannose therapy of patients with carbohydrate-deficient glycoprotein syndrome type 1A","volume":"87","author":"Kjaergaard","year":"1998","journal-title":"Acta Paediatr"},{"key":"10.1074\/jbc.M113.544064_bib7","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s004310050889","article-title":"Mannose supplementation in carbohydrate-deficient glycoprotein syndrome type I and phosphomannomutase deficiency","volume":"157","author":"Mayatepek","year":"1998","journal-title":"Eur. J. Pediatr"},{"key":"10.1074\/jbc.M113.544064_bib8","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1074\/mcp.M112.027151","article-title":"Mass isotopomer analysis of metabolically labeled nucleotide sugars and N- and O-glycans for tracing nucleotide sugar metabolisms","volume":"12","author":"Nakajima","year":"2013","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/jbc.M113.544064_bib9","doi-asserted-by":"crossref","first-page":"10193","DOI":"10.1074\/jbc.M110.194241","article-title":"Mannose efflux from the cells: a potential source of mannose in blood","volume":"286","author":"Sharma","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.544064_bib10","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0003-2697(74)90248-6","article-title":"A comparison of three methods of glycogen measurement in tissues","volume":"60","author":"Passonneau","year":"1974","journal-title":"Anal. Biochem"},{"key":"10.1074\/jbc.M113.544064_bib11","doi-asserted-by":"crossref","first-page":"6566","DOI":"10.1021\/ac049198m","article-title":"Acylic sugar derivatives for GC\/MS analysis of 13C-enrichment during carbohydrate metabolism","volume":"76","author":"Price","year":"2004","journal-title":"Anal. Chem"},{"key":"10.1074\/jbc.M113.544064_bib12","doi-asserted-by":"crossref","first-page":"42626","DOI":"10.1074\/jbc.M111.282046","article-title":"Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect","volume":"286","author":"Scott","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.544064_bib13","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/978-1-59745-244-1_11","article-title":"Determination of metabolic flux ratios from 13C-experiments and gas chromatography-mass spectrometry data: protocol and principles","volume":"358","author":"Nanchen","year":"2007","journal-title":"Methods Mol. Biol"},{"key":"10.1074\/jbc.M113.544064_bib14","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/bit.10393","article-title":"Correcting mass isotopomer distributions for naturally occurring isotopes","volume":"80","author":"van Winden","year":"2002","journal-title":"Biotechnol. Bioeng"},{"key":"10.1074\/jbc.M113.544064_bib15","doi-asserted-by":"crossref","first-page":"6529","DOI":"10.1128\/AEM.01178-10","article-title":"Deletion of genes encoding cytochrome oxidases and quinol monooxygenase blocks the aerobic-anaerobic shift in Escherichia coli K-12 MG1655","volume":"76","author":"Portnoy","year":"2010","journal-title":"Appl. Environ. Microbiol"},{"key":"10.1074\/jbc.M113.544064_bib16","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1007\/s11064-005-8801-4","article-title":"Compartmentation of lactate originating from glycogen and glucose in cultured astrocytes","volume":"30","author":"Sickmann","year":"2005","journal-title":"Neurochem. Res"},{"key":"10.1074\/jbc.M113.544064_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1255\/ejms.527","article-title":"Derivatization in mass spectrometry-1. Silylation","volume":"9","author":"Halket","year":"2003","journal-title":"Eur. J. Mass Spectrom. (Chichester, Eng.)"},{"key":"10.1074\/jbc.M113.544064_bib18","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1080\/10409230500542575","article-title":"Stimulation of N-linked glycosylation and lipid-linked oligosaccharide synthesis by stress responses in metazoan cells","volume":"41","author":"Lehrman","year":"2006","journal-title":"Crit. Rev. Biochem. Mol. Biol"},{"key":"10.1074\/jbc.M113.544064_bib19","doi-asserted-by":"crossref","first-page":"12076","DOI":"10.1074\/jbc.M400431200","article-title":"Activation of glycogen phosphorylase with 5-aminoimidazole-4-carboxamide riboside (AICAR). Assessment of glycogen as a precursor of mannosyl residues in glycoconjugates","volume":"279","author":"Shang","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.544064_bib20","doi-asserted-by":"crossref","first-page":"6034","DOI":"10.1002\/j.1460-2075.1995.tb00292.x","article-title":"Endoplasmic reticulum-to-cytosol transport of free polymannose oligosaccharides in permeabilized HepG2 cells","volume":"14","author":"Moore","year":"1995","journal-title":"EMBO J"},{"key":"10.1074\/jbc.M113.544064_bib21","doi-asserted-by":"crossref","first-page":"44747","DOI":"10.1074\/jbc.M205001200","article-title":"Rapid activation of glycogen phosphorylase by the endoplasmic reticulum unfolded protein response","volume":"277","author":"Gill","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.544064_bib22","first-page":"E640","article-title":"Glycogen: a carbohydrate source for GLUT-1 glycosylation during glucose deprivation of 3T3-L1 adipocytes","volume":"270","author":"McMahon","year":"1996","journal-title":"Am. J. Physiol"},{"key":"10.1074\/jbc.M113.544064_bib23","doi-asserted-by":"crossref","first-page":"23123","DOI":"10.1074\/jbc.272.37.23123","article-title":"Human fibroblasts prefer mannose over glucose as a source of mannose for N-glycosylation: evidence for the functional importance of transported mannose","volume":"272","author":"Panneerselvam","year":"1997","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M113.544064_bib24","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.febslet.2011.12.027","article-title":"Functional characterisation of human SGLT-5 as a novel kidney-specific sodium-dependent sugar transporter","volume":"586","author":"Grempler","year":"2012","journal-title":"FEBS Lett"},{"key":"10.1074\/jbc.M113.544064_bib25","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1385\/ENDO:24:2:105","article-title":"Enzyme-to-enzyme channeling in the early steps of glycolysis in rat pancreatic islets","volume":"24","author":"Malaisse","year":"2004","journal-title":"Endocrine"},{"key":"10.1074\/jbc.M113.544064_bib26","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1016\/S0021-9258(19)44210-5","article-title":"Mannose 6-phosphate: anomeric form used by phosphomannose isomerase and its 1-epimerization by phosphoglucose isomerase","volume":"248","author":"Rose","year":"1973","journal-title":"J. Biol. Chem"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820444928?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820444928?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M113.544064","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T08:46:02Z","timestamp":1641285962000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820444928"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":26,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["S0021925820444928"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m113.544064","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]}}}