{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:48:33Z","timestamp":1791809313258,"version":"4.3.4"},"reference-count":65,"publisher":"Elsevier BV","issue":"49","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,9]],"date-time":"2020-09-09T00:00:00Z","timestamp":1599609600000},"content-version":"vor","delay-in-days":2109,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1074\/jbc.m114.592295","type":"journal-article","created":{"date-parts":[[2014,10,4]],"date-time":"2014-10-04T02:05:16Z","timestamp":1412388316000},"page":"33730-33740","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"title":["RING Finger Protein RNF207, a Novel Regulator of Cardiac Excitation"],"prefix":"10.1016","volume":"289","author":[{"given":"Karim","family":"Roder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas A.","family":"Werdich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Yun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise E.","family":"Organ-Darling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karni S.","family":"Moshal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung Min","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yichun","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bum-Rak","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calum A.","family":"MacRae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gideon","family":"Koren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M114.592295_bib1","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1161\/01.CIR.90.5.2534","article-title":"Sudden cardiac death in heart failure: the role of abnormal repolarization","volume":"90","author":"Tomaselli","year":"1994","journal-title":"Circulation"},{"key":"10.1074\/jbc.M114.592295_bib2","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1097\/HCO.0b013e32833846b3","article-title":"Recent progress in congenital long QT syndrome","volume":"25","author":"Lu","year":"2010","journal-title":"Curr. Opin. Cardiol"},{"key":"10.1074\/jbc.M114.592295_bib3","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.ajhg.2010.04.017","article-title":"Identification of a Kir3.4 mutation in congenital long QT syndrome","volume":"86","author":"Yang","year":"2010","journal-title":"Am. J. Hum. Genet"},{"key":"10.1074\/jbc.M114.592295_bib4","doi-asserted-by":"crossref","first-page":"4125","DOI":"10.1113\/jphysiol.2013.254920","article-title":"Long QT syndrome: beyond the causal mutation","volume":"591","author":"Amin","year":"2013","journal-title":"J. Physiol"},{"key":"10.1074\/jbc.M114.592295_bib5","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.gde.2007.04.010","article-title":"Genetic determinants of QT interval variation and sudden cardiac death","volume":"17","author":"Newton-Cheh","year":"2007","journal-title":"Curr. Opin. Genet. Dev"},{"key":"10.1074\/jbc.M114.592295_bib6","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1034\/j.1399-0004.2001.590305.x","article-title":"Familial aggregation of QT-interval variability in a general population: results from the NHLBI Family Heart Study","volume":"59","author":"Hong","year":"2001","journal-title":"Clin. Genet"},{"key":"10.1074\/jbc.M114.592295_bib7","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.hrthm.2004.11.009","article-title":"QT interval is a heritable quantitative trait with evidence of linkage to chromosome 3 in a genome-wide linkage analysis: the Framingham Heart Study","volume":"2","author":"Newton-Cheh","year":"2005","journal-title":"Heart Rhythm"},{"key":"10.1074\/jbc.M114.592295_bib8","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1161\/CIRCEP.109.858894","article-title":"Clinical correlates and heritability of QT interval duration in blacks: the Jackson Heart Study","volume":"2","author":"Akylbekova","year":"2009","journal-title":"Circ. Arrhythm. Electrophysiol"},{"key":"10.1074\/jbc.M114.592295_bib9","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1111\/j.1365-2796.2008.02026.x","article-title":"Common candidate gene variants are associated with QT interval duration in the general population","volume":"265","author":"Marjamaa","year":"2009","journal-title":"J. Intern. Med"},{"key":"10.1074\/jbc.M114.592295_bib10","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1038\/ng.362","article-title":"Common variants at ten loci modulate the QT interval duration in the QTSCD Study","volume":"41","author":"Pfeufer","year":"2009","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M114.592295_bib11","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/ng.364","article-title":"Common variants at ten loci influence QT interval duration in the QTGEN Study","volume":"41","author":"Newton-Cheh","year":"2009","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M114.592295_bib12","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1038\/mp.2008.52","article-title":"Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia","volume":"14","author":"Volpi","year":"2009","journal-title":"Mol. Psychiatry"},{"key":"10.1074\/jbc.M114.592295_bib13","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1161\/CIRCULATIONAHA.108.821082","article-title":"Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization","volume":"120","author":"Milan","year":"2009","journal-title":"Circulation"},{"key":"10.1074\/jbc.M114.592295_bib14","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1038\/tpj.2010.76","article-title":"Genome-wide association study of antipsychotic-induced QTc interval prolongation","volume":"12","author":"Aberg","year":"2012","journal-title":"Pharmacogenomics J"},{"key":"10.1074\/jbc.M114.592295_bib15","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1111\/j.1540-8159.1998.tb00148.x","article-title":"Taking the \u201cidio\u201d out of \u201cidiosyncratic\u201d: predicting torsades de pointes","volume":"21","author":"Roden","year":"1998","journal-title":"Pacing Clin. Electrophysiol"},{"key":"10.1074\/jbc.M114.592295_bib16","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1161\/CIRCGENETICS.110.959049","article-title":"Common genetic variants, QT interval, and sudden cardiac death in a Finnish population-based study","volume":"4","author":"Noseworthy","year":"2011","journal-title":"Circ. Cardiovasc. Genet"},{"key":"10.1074\/jbc.M114.592295_bib17","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1146\/annurev.biochem.78.101807.093809","article-title":"RING domain E3 ubiquitin ligases","volume":"78","author":"Deshaies","year":"2009","journal-title":"Annu. Rev. Biochem"},{"key":"10.1074\/jbc.M114.592295_bib18","doi-asserted-by":"crossref","first-page":"H681","DOI":"10.1152\/ajpheart.00152.2004","article-title":"Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5","volume":"287","author":"Folco","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol"},{"key":"10.1074\/jbc.M114.592295_bib19","doi-asserted-by":"crossref","first-page":"H2012","DOI":"10.1152\/ajpheart.01374.2007","article-title":"Posttranslational modification of voltage-dependent potassium channel Kv1.5: COOH-terminal palmitoylation modulates its biological properties","volume":"294","author":"Jindal","year":"2008","journal-title":"Am. J. Physiol. Heart Circ. Physiol"},{"key":"10.1074\/jbc.M114.592295_bib20","doi-asserted-by":"crossref","first-page":"H1525","DOI":"10.1152\/ajpheart.00479.2009","article-title":"Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines","volume":"299","author":"Ren","year":"2010","journal-title":"Am. J. Physiol. Heart Circ. Physiol"},{"key":"10.1074\/jbc.M114.592295_bib21","doi-asserted-by":"crossref","first-page":"H589","DOI":"10.1152\/ajpheart.00385.2012","article-title":"Interactions between hERG and KCNQ1 \u03b1-subunits are mediated by their COOH termini and modulated by cAMP","volume":"304","author":"Organ-Darling","year":"2013","journal-title":"Am. J. Physiol. Heart Circ. Physiol"},{"key":"10.1074\/jbc.M114.592295_bib22","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1177\/153537020623100705","article-title":"Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting","volume":"231","author":"Ciechanover","year":"2006","journal-title":"Exp. Biol. Med"},{"key":"10.1074\/jbc.M114.592295_bib23","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1515\/BC.2006.153","article-title":"The K+ channel gene, Kcnb1: genomic structure and characterization of its 5\u2032-regulatory region as part of an overlapping gene group","volume":"387","author":"Roder","year":"2006","journal-title":"Biol. Chem"},{"key":"10.1074\/jbc.M114.592295_bib24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12192-008-0060-2","article-title":"Computational analysis of the human HSPH\/HSPA\/DNAJ family and cloning of a human HSPH\/HSPA\/DNAJ expression library","volume":"14","author":"Hageman","year":"2009","journal-title":"Cell Stress Chaperones"},{"key":"10.1074\/jbc.M114.592295_bib25","first-page":"2246","article-title":"Mechanisms of cardiac arrhythmias and sudden death in transgenic rabbits with long QT syndrome","volume":"118","author":"Brunner","year":"2008","journal-title":"J. Clin. Invest"},{"key":"10.1074\/jbc.M114.592295_bib26","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1038\/nature09249","article-title":"Wnt11 patterns a myocardial electrical gradient through regulation of the L-type Ca2+ channel","volume":"466","author":"Pan\u00e1kov\u00e1","year":"2010","journal-title":"Nature"},{"key":"10.1074\/jbc.M114.592295_bib27","doi-asserted-by":"crossref","first-page":"e78","DOI":"10.1371\/journal.pgen.0030078","article-title":"p53 activation by knockdown technologies","volume":"3","author":"Robu","year":"2007","journal-title":"PLoS Genet"},{"key":"10.1074\/jbc.M114.592295_bib28","doi-asserted-by":"crossref","first-page":"e50030","DOI":"10.1371\/journal.pone.0050030","article-title":"Origin and diversification of TRIM ubiquitin ligases","volume":"7","author":"Mar\u00edn","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.M114.592295_bib29","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1002\/iub.580","article-title":"TRIM family: pleiotropy and diversification through homomultimer and heteromultimer formation","volume":"64","author":"Napolitano","year":"2012","journal-title":"IUBMB Life"},{"key":"10.1074\/jbc.M114.592295_bib30","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1038\/nri2413","article-title":"TRIM family proteins and their emerging roles in innate immunity","volume":"8","author":"Ozato","year":"2008","journal-title":"Nat. Rev. Immunol"},{"key":"10.1074\/jbc.M114.592295_bib31","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1242\/dev.02279","article-title":"Notch1b and neuregulin are required for specification of central cardiac conduction tissue","volume":"133","author":"Milan","year":"2006","journal-title":"Development"},{"key":"10.1074\/jbc.M114.592295_bib32","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.pbiomolbio.2012.07.006","article-title":"The zebrafish as a novel animal model to study the molecular mechanisms of mechano-electrical feedback in the heart","volume":"110","author":"Werdich","year":"2012","journal-title":"Prog. Biophys. Mol. Biol"},{"key":"10.1074\/jbc.M114.592295_bib33","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.bbrc.2010.04.157","article-title":"Identification and expression analysis of kcnh2 genes in the zebrafish","volume":"396","author":"Leong","year":"2010","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"10.1074\/jbc.M114.592295_bib34","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/j.taap.2003.07.012","article-title":"Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia","volume":"193","author":"Langheinrich","year":"2003","journal-title":"Toxicol. Appl. Pharmacol"},{"key":"10.1074\/jbc.M114.592295_bib35","doi-asserted-by":"crossref","first-page":"11316","DOI":"10.1073\/pnas.0702724104","article-title":"Zebrafish model for human long QT syndrome","volume":"104","author":"Arnaout","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M114.592295_bib36","doi-asserted-by":"crossref","first-page":"23509","DOI":"10.1074\/jbc.M701006200","article-title":"Co-chaperone FKBP38 promotes HERG trafficking","volume":"282","author":"Walker","year":"2007","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.592295_bib37","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1074\/jbc.M109.024000","article-title":"Hsp40 chaperones promote degradation of the HERG potassium channel","volume":"285","author":"Walker","year":"2010","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.592295_bib38","doi-asserted-by":"crossref","first-page":"D610","DOI":"10.1093\/nar\/gkl996","article-title":"Ensembl 2007","volume":"35","author":"Hubbard","year":"2007","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M114.592295_bib39","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/nar\/30.1.207","article-title":"Gene Expression Omnibus: NCBI gene expression and hybridization array data repository","volume":"30","author":"Edgar","year":"2002","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M114.592295_bib40","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/1472-6793-9-23","article-title":"Transcriptional profile of isoproterenol-induced cardiomyopathy and comparison to exercise-induced cardiac hypertrophy and human cardiac failure","volume":"9","author":"Galindo","year":"2009","journal-title":"BMC Physiol"},{"key":"10.1074\/jbc.M114.592295_bib41","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/CCM.0b013e3181b427e8","article-title":"Gene expression profiling: classification of mice with left ventricle systolic dysfunction using microarray analysis","volume":"38","author":"Wong","year":"2010","journal-title":"Crit. Care Med"},{"key":"10.1074\/jbc.M114.592295_bib42","doi-asserted-by":"crossref","first-page":"33487","DOI":"10.1074\/jbc.M605536200","article-title":"Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling","volume":"281","author":"Bush","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.592295_bib43","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.cardiores.2005.02.003","article-title":"Hypoxia, electrical uncoupling, and conduction slowing: role of conduction reserve","volume":"66","author":"van Rijen","year":"2005","journal-title":"Cardiovasc. Res"},{"key":"10.1074\/jbc.M114.592295_bib44","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1038\/ng.716","article-title":"Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction","volume":"42","author":"Sotoodehnia","year":"2010","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M114.592295_bib45","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1038\/nprot.2009.86","article-title":"Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm","volume":"4","author":"Kumar","year":"2009","journal-title":"Nat. Protoc"},{"key":"10.1074\/jbc.M114.592295_bib46","doi-asserted-by":"crossref","first-page":"e46688","DOI":"10.1371\/journal.pone.0046688","article-title":"Predicting the functional effect of amino acid substitutions and indels","volume":"7","author":"Choi","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.M114.592295_bib47","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/gepi.20297","article-title":"Estimation of significance thresholds for genomewide association scans","volume":"32","author":"Dudbridge","year":"2008","journal-title":"Genet. Epidemiol"},{"key":"10.1074\/jbc.M114.592295_bib48","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1038\/ng1801","article-title":"Evaluating coverage of genome-wide association studies","volume":"38","author":"Barrett","year":"2006","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M114.592295_bib49","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1042\/BJ20100985","article-title":"E2s: structurally economical and functionally replete","volume":"433","author":"Wenzel","year":"2011","journal-title":"Biochem. J"},{"key":"10.1074\/jbc.M114.592295_bib50","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1038\/nsmb1295","article-title":"E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages","volume":"14","author":"Christensen","year":"2007","journal-title":"Nat. Struct. Mol. Biol"},{"key":"10.1074\/jbc.M114.592295_bib51","doi-asserted-by":"crossref","first-page":"14537","DOI":"10.1074\/jbc.C000881200","article-title":"The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation","volume":"276","author":"Hashizume","year":"2001","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.592295_bib52","doi-asserted-by":"crossref","first-page":"49668","DOI":"10.1074\/jbc.M208593200","article-title":"MdmX is a RING finger ubiquitin ligase capable of synergistically enhancing Mdm2 ubiquitination","volume":"277","author":"Badciong","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.592295_bib53","doi-asserted-by":"crossref","first-page":"e87","DOI":"10.1161\/01.RES.0000079028.31393.15","article-title":"Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG","volume":"92","author":"Ficker","year":"2003","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.592295_bib54","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1161\/CIRCRESAHA.110.227835","article-title":"Reciprocal control of hERG stability by Hsp70 and Hsc70 with implication for restoration of LQT2 mutant stability","volume":"108","author":"Li","year":"2011","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.592295_bib55","doi-asserted-by":"crossref","first-page":"e29885","DOI":"10.1371\/journal.pone.0029885","article-title":"Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum","volume":"7","author":"Wang","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1074\/jbc.M114.592295_bib56","doi-asserted-by":"crossref","first-page":"9406","DOI":"10.1021\/bi00154a012","article-title":"Unfolded proteins stimulate molecular chaperone Hsc70 ATPase by accelerating ADP\/ATP exchange","volume":"31","author":"Sadis","year":"1992","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M114.592295_bib57","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.bbamcr.2011.09.003","article-title":"The Hsp90 chaperone machinery: conformational dynamics and regulation by co-chaperones","volume":"1823","author":"Li","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M114.592295_bib58","doi-asserted-by":"crossref","first-page":"4535","DOI":"10.1128\/MCB.19.6.4535","article-title":"Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions","volume":"19","author":"Ballinger","year":"1999","journal-title":"Mol. Cell Biol"},{"key":"10.1074\/jbc.M114.592295_bib59","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/cvr\/cvt200","article-title":"Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins","volume":"100","author":"Iwai","year":"2013","journal-title":"Cardiovasc. Res"},{"key":"10.1074\/jbc.M114.592295_bib60","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/35050509","article-title":"The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation","volume":"3","author":"Meacham","year":"2001","journal-title":"Nat. Cell Biol"},{"key":"10.1074\/jbc.M114.592295_bib61","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1007\/s00018-004-4464-6","article-title":"Hsp70 chaperones: cellular functions and molecular mechanism","volume":"62","author":"Mayer","year":"2005","journal-title":"Cell Mol. Life Sci"},{"key":"10.1074\/jbc.M114.592295_bib62","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1161\/HYPERTENSIONAHA.110.165803","article-title":"Augmented rififylin is a risk factor linked to aberrant cardiomyocyte function, short-QT interval and hypertension","volume":"57","author":"Gopalakrishnan","year":"2011","journal-title":"Hypertension"},{"key":"10.1074\/jbc.M114.592295_bib63","doi-asserted-by":"crossref","first-page":"138","DOI":"10.3389\/fgene.2012.00138","article-title":"Increased expression of Rififylin in a < 330 kb congenic strain is linked to impaired endosomal recycling in proximal tubules","volume":"3","author":"Gopalakrishnan","year":"2012","journal-title":"Front Genet"},{"key":"10.1074\/jbc.M114.592295_bib64","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/ibd.20010","article-title":"Litaf\/Simple protein is increased in intestinal tissues from patients with CD and UC, but is unlikely to function as a transcription factor","volume":"13","author":"Huang","year":"2007","journal-title":"Inflamm. Bowel. Dis"},{"key":"10.1074\/jbc.M114.592295_bib65","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/jnr.20628","article-title":"SIMPLE interacts with NEDD4 and TSG101: evidence for a role in lysosomal sorting and implications for Charcot-Marie-Tooth disease","volume":"82","author":"Shirk","year":"2005","journal-title":"J. Neurosci. Res"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820473259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820473259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M114.592295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T22:18:55Z","timestamp":1679523535000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820473259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":65,"journal-issue":{"issue":"49","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["S0021925820473259"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m114.592295","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"RING Finger Protein RNF207, a Novel Regulator of Cardiac Excitation","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M114.592295","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2014 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}