{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T06:19:15Z","timestamp":1792045155939,"version":"4.4.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,22]],"date-time":"2020-09-22T00:00:00Z","timestamp":1600732800000},"content-version":"vor","delay-in-days":2091,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1074\/jbc.m114.597377","type":"journal-article","created":{"date-parts":[[2014,12,9]],"date-time":"2014-12-09T00:06:56Z","timestamp":1418083616000},"page":"2419-2430","source":"Crossref","is-referenced-by-count":11,"title":["The Src Homology and Collagen A (ShcA) Adaptor Protein Is Required for the Spatial Organization of the Costamere\/Z-disk Network during Heart Development"],"prefix":"10.1016","volume":"290","author":[{"given":"Mohamed","family":"Mlih","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lionel","family":"Host","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Niederhoffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Monassier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00f4me","family":"Terrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Messaddeq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Radke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Gotthardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Bruban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Kober","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"Bernard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Canet-Soulas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Abt-Jijon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Boucher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel L.","family":"Matz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M114.597377_bib1","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1056\/NEJMra0902923","article-title":"Inherited cardiomyopathies","volume":"364","author":"Watkins","year":"2011","journal-title":"N. Engl. J. Med"},{"key":"10.1074\/jbc.M114.597377_bib2","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/nrg1470","article-title":"Molecular genetics and genomics of heart failure","volume":"5","author":"Liew","year":"2004","journal-title":"Nat. Rev. Genet"},{"key":"10.1074\/jbc.M114.597377_bib3","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/nm0502-459","article-title":"ErbB2 is essential in the prevention of dilated cardiomyopathy","volume":"8","author":"Crone","year":"2002","journal-title":"Nat. Med"},{"key":"10.1074\/jbc.M114.597377_bib4","doi-asserted-by":"crossref","first-page":"8880","DOI":"10.1073\/pnas.122249299","article-title":"Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy","volume":"99","author":"Ozcelik","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M114.597377_bib5","doi-asserted-by":"crossref","first-page":"6322","DOI":"10.1038\/sj.onc.1204776","article-title":"Signaling via Shc family adapter proteins","volume":"20","author":"Ravichandran","year":"2001","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M114.597377_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BJ20120769","article-title":"Teaching an old dogma new tricks: twenty years of Shc adaptor signalling","volume":"447","author":"Wills","year":"2012","journal-title":"Biochem. J"},{"key":"10.1074\/jbc.M114.597377_bib7","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1016\/S0960-9822(96)00748-8","article-title":"The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239\/240) that mediate protein-protein interactions","volume":"6","author":"van der Geer","year":"1996","journal-title":"Curr. Biol"},{"key":"10.1074\/jbc.M114.597377_bib8","first-page":"223","article-title":"Cloning and mutational analysis of the Shc-phosphotyrosine interaction\/phosphotyrosine-binding domain","volume":"84","author":"Yajnik","year":"1998","journal-title":"Methods Mol. Biol"},{"key":"10.1074\/jbc.M114.597377_bib9","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1101\/gad.14.9.1132","article-title":"The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo","volume":"14","author":"Lai","year":"2000","journal-title":"Genes Dev"},{"key":"10.1074\/jbc.M114.597377_bib10","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1161\/CIRCRESAHA.110.233924","article-title":"The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function","volume":"108","author":"Vanderlaan","year":"2011","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.597377_bib11","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0092-8674(00)81604-9","article-title":"A requirement for caveolin-1 and associated kinase Fyn in integrin signaling and anchorage-dependent cell growth","volume":"94","author":"Wary","year":"1998","journal-title":"Cell"},{"key":"10.1074\/jbc.M114.597377_bib12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.pbiomolbio.2009.01.012","article-title":"Caveolae, ion channels and cardiac arrhythmias","volume":"98","author":"Balijepalli","year":"2008","journal-title":"Prog. Biophys. Mol. Biol"},{"key":"10.1074\/jbc.M114.597377_bib13","first-page":"976","article-title":"Plasma membrane Ca2+-ATPase isoform 4 antagonizes cardiac hypertrophy in association with calcineurin inhibition in rodents","volume":"119","author":"Wu","year":"2009","journal-title":"J. Clin. Investig"},{"key":"10.1074\/jbc.M114.597377_bib14","doi-asserted-by":"crossref","first-page":"23341","DOI":"10.1074\/jbc.M513341200","article-title":"The sarcolemmal calcium pump, \u03b1-1 syntrophin, and neuronal nitric-oxide synthase are parts of a macromolecular protein complex","volume":"281","author":"Williams","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.597377_bib15","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/sj.cdd.4401997","article-title":"p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis","volume":"14","author":"Pellegrini","year":"2007","journal-title":"Cell Death Differ"},{"key":"10.1074\/jbc.M114.597377_bib16","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1111\/j.1749-6632.2003.tb07230.x","article-title":"Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants","volume":"986","author":"Goellner","year":"2003","journal-title":"Ann. N.Y. Acad. Sci"},{"key":"10.1074\/jbc.M114.597377_bib17","doi-asserted-by":"crossref","first-page":"31318","DOI":"10.1074\/jbc.M307557200","article-title":"Novel functional interaction between the plasma membrane Ca2+ pump 4b and the proapoptotic tumor suppressor Ras-associated factor 1 (RASSF1)","volume":"279","author":"Armesilla","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.597377_bib18","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1161\/01.RES.78.2.188","article-title":"SM22\u03b1alpha, a marker of adult smooth muscle, is expressed in multiple myogenic lineages during embryogenesis","volume":"78","author":"Li","year":"1996","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.597377_bib19","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1093\/hmg\/ddq570","article-title":"Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin","volume":"20","author":"Malhowski","year":"2011","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.M114.597377_bib20","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1126\/science.1082095","article-title":"LRP: role in vascular wall integrity and protection from atherosclerosis","volume":"300","author":"Boucher","year":"2003","journal-title":"Science"},{"key":"10.1074\/jbc.M114.597377_bib21","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1093\/hmg\/ddh114","article-title":"Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxia","volume":"13","author":"Seznec","year":"2004","journal-title":"Hum. Mol. Genet"},{"key":"10.1074\/jbc.M114.597377_bib22","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1161\/01.RES.76.5.907","article-title":"Echocardiographic assessment of left ventricular mass and systolic function in mice","volume":"76","author":"Gardin","year":"1995","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.597377_bib23","first-page":"H1672","article-title":"In vivo assessment of LV mass in mice using high-frequency cardiac ultrasound: necropsy validation","volume":"266","author":"Manning","year":"1994","journal-title":"Am. J. Physiol"},{"key":"10.1074\/jbc.M114.597377_bib24","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/j.ejcts.2006.02.014","article-title":"Assessment of left ventricular ejection fraction may invalidate the reliability of EuroSCORE","volume":"29","author":"Jakobsen","year":"2006","journal-title":"Eur. J. Cardiothorac. Surg"},{"key":"10.1074\/jbc.M114.597377_bib25","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1083\/jcb.148.5.1035","article-title":"A dual role of erbB2 in myelination and in expansion of the schwann cell precursor pool","volume":"148","author":"Garratt","year":"2000","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M114.597377_bib26","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1002\/mrm.20373","article-title":"Myocardial blood flow mapping in mice using high-resolution spin labeling magnetic resonance imaging: influence of ketamine\/xylazine and isoflurane anesthesia","volume":"53","author":"Kober","year":"2005","journal-title":"Magn. Reson. Med"},{"key":"10.1074\/jbc.M114.597377_bib27","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/nbm.1645","article-title":"Quantification of myocardial blood flow and flow reserve in rats using arterial spin labeling MRI: comparison with a fluorescent microsphere technique","volume":"24","author":"Jacquier","year":"2011","journal-title":"NMR Biomed"},{"key":"10.1074\/jbc.M114.597377_bib28","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/sj.bjp.0703568","article-title":"Vascular bed heterogeneity in age-related endothelial dysfunction with respect to NO and eicosanoids","volume":"131","author":"Matz","year":"2000","journal-title":"Br. J. Pharmacol"},{"key":"10.1074\/jbc.M114.597377_bib29","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1002\/elps.200305392","article-title":"Vertical agarose gel electrophoresis and electroblotting of high-molecular-weight proteins","volume":"24","author":"Warren","year":"2003","journal-title":"Electrophoresis"},{"key":"10.1074\/jbc.M114.597377_bib30","doi-asserted-by":"crossref","first-page":"2747","DOI":"10.1242\/jcs.109.11.2747","article-title":"The central Z-disk region of titin is assembled from a novel repeat in variable","volume":"109","author":"Gautel","year":"1996","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.M114.597377_bib31","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.bbrc.2012.05.041","article-title":"Smooth muscle protein 22 \u03b1-Cre is expressed in myeloid cells in mice","volume":"422","author":"Shen","year":"2012","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"10.1074\/jbc.M114.597377_bib32","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1177\/0192623309335060","article-title":"Histology atlas of the developing mouse heart with emphasis on E11.5 to E18.5","volume":"37","author":"Savolainen","year":"2009","journal-title":"Toxicol. Pathol"},{"key":"10.1074\/jbc.M114.597377_bib33","doi-asserted-by":"crossref","first-page":"16775","DOI":"10.1074\/jbc.M110.212878","article-title":"Differential signaling by adaptor molecules LRP1 and ShcA regulates adipogenesis by the insulin-like growth factor-1 receptor","volume":"286","author":"Woldt","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.597377_bib34","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/nrm1198","article-title":"Titin: properties and family relationships","volume":"4","author":"Tskhovrebova","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"10.1074\/jbc.M114.597377_bib35","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1161\/01.RES.0000116143.74830.A9","article-title":"At the crossroads of myocardial signaling: the role of Z-discs in intracellular signaling and cardiac function","volume":"94","author":"Pyle","year":"2004","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.597377_bib36","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0092-8674(03)00037-0","article-title":"Sensing stretch is fundamental","volume":"112","author":"Epstein","year":"2003","journal-title":"Cell"},{"key":"10.1074\/jbc.M114.597377_bib37","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1161\/CIRCRESAHA.112.267286","article-title":"Neuregulin in cardiovascular development and disease","volume":"111","author":"Odiete","year":"2012","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.597377_bib38","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1007\/s11897-010-0003-y","article-title":"Neuregulin signaling and heart failure","volume":"7","author":"Jiang","year":"2010","journal-title":"Curr. Heart Fail. Rep"},{"key":"10.1074\/jbc.M114.597377_bib39","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/cm.970320305","article-title":"Nebulette: a 107 kDa nebulin-like protein in cardiac muscle","volume":"32","author":"Moncman","year":"1995","journal-title":"Cell Motil. Cytoskeleton"},{"key":"10.1074\/jbc.M114.597377_bib40","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.yjmcc.2013.04.021","article-title":"Altered regional cardiac wall mechanics are associated with differential cardiomyocyte calcium handling due to nebulette mutations in preclinical inherited dilated cardiomyopathy","volume":"60","author":"Maiellaro-Rafferty","year":"2013","journal-title":"J. Mol. Cell. Cardiol"},{"key":"10.1074\/jbc.M114.597377_bib41","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1016\/j.jacc.2010.05.045","article-title":"Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosis","volume":"56","author":"Purevjav","year":"2010","journal-title":"J. Am. Coll. Cardiol"},{"key":"10.1074\/jbc.M114.597377_bib42","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1161\/01.RES.0000117769.88862.F8","article-title":"The giant protein titin: a major player in myocardial mechanics, signaling, and disease","volume":"94","author":"Granzier","year":"2004","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M114.597377_bib43","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/ng815","article-title":"Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy","volume":"30","author":"Gerull","year":"2002","journal-title":"Nat. Genet"},{"key":"10.1074\/jbc.M114.597377_bib44","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1038\/nm.2693","article-title":"RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing","volume":"18","author":"Guo","year":"2012","journal-title":"Nat. Med"},{"key":"10.1074\/jbc.M114.597377_bib45","doi-asserted-by":"crossref","first-page":"3444","DOI":"10.1073\/pnas.0608543104","article-title":"Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy","volume":"104","author":"Radke","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M114.597377_bib46","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1056\/NEJMoa1110186","article-title":"Truncations of titin causing dilated cardiomyopathy","volume":"366","author":"Herman","year":"2012","journal-title":"New Engl. J. Med"},{"key":"10.1074\/jbc.M114.597377_bib47","doi-asserted-by":"crossref","first-page":"11375","DOI":"10.1073\/pnas.172360799","article-title":"Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice","volume":"99","author":"Zhao","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M114.597377_bib48","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1242\/jcs.108.9.3029","article-title":"Characterization of a 5.4 kb cDNA fragment from the Z-line region of rabbit cardiac titin reveals phosphorylation sites for proline-directed kinases","volume":"108","author":"Sebesty\u00e9n","year":"1995","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.M114.597377_bib49","doi-asserted-by":"crossref","first-page":"3061","DOI":"10.1242\/jcs.066712","article-title":"\u03b2-Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release","volume":"123","author":"Sharma","year":"2010","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.M114.597377_bib50","first-page":"235","article-title":"Early differentiation of the heart in mouse embryos","volume":"133","author":"Kaufman","year":"1981","journal-title":"J. Anat"},{"key":"10.1074\/jbc.M114.597377_bib51","doi-asserted-by":"crossref","first-page":"745185","DOI":"10.5402\/2012\/745185","article-title":"Doxorubicin and NRG-1\/erbB4-deficiency affect gene expression profile: involving protein homeostasis in mouse","volume":"2012","author":"Vasti","year":"2012","journal-title":"ISRN Cardiol"},{"key":"10.1074\/jbc.M114.597377_bib52","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1161\/CIRCULATIONAHA.107.690487","article-title":"Role of neuregulin-1\/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure","volume":"116","author":"Lemmens","year":"2007","journal-title":"Circulation"},{"key":"10.1074\/jbc.M114.597377_bib53","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.yjmcc.2011.06.016","article-title":"Neuregulin-1\u03b2 for the treatment of systolic heart failure","volume":"51","author":"Sawyer","year":"2011","journal-title":"J. Mol. Cell. Cardiol"},{"key":"10.1074\/jbc.M114.597377_bib54","first-page":"61","article-title":"Shc dominant negative disrupts cell cycle progression in both G0-G1 and G2-M of ErbB2-positive breast cancer cells","volume":"10","author":"Stevenson","year":"1999","journal-title":"Cell Growth Differ"},{"key":"10.1074\/jbc.M114.597377_bib55","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1002\/jcp.22354","article-title":"Expression, localization, and regulation of the neuregulin receptor ErbB3 in mouse heart","volume":"226","author":"Campreci\u00f3s","year":"2011","journal-title":"J. Cell Physiol"},{"key":"10.1074\/jbc.M114.597377_bib56","doi-asserted-by":"crossref","first-page":"10261","DOI":"10.1074\/jbc.273.17.10261","article-title":"Neuregulins promote survival and growth of cardiac myocytes: persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes","volume":"273","author":"Zhao","year":"1998","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M114.597377_bib57","doi-asserted-by":"crossref","first-page":"4999","DOI":"10.1242\/dev.124.24.4999","article-title":"ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2-and heregulin-deficient mice","volume":"124","author":"Erickson","year":"1997","journal-title":"Development"},{"key":"10.1074\/jbc.M114.597377_bib58","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.yjmcc.2010.02.016","article-title":"Mechanical stress-induced sarcomere assembly for cardiac muscle growth in length and width","volume":"48","author":"Russell","year":"2010","journal-title":"J. Mol. Cell. Cardiol"},{"key":"10.1074\/jbc.M114.597377_bib59","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.bbamem.2013.07.017","article-title":"Mechanisms of talin-dependent integrin signaling and crosstalk","volume":"1838","author":"Das","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M114.597377_bib60","doi-asserted-by":"crossref","first-page":"C457","DOI":"10.1152\/ajpcell.00380.2002","article-title":"Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42\/44 MAP kinase in cardiac fibroblasts","volume":"284","author":"Cohen","year":"2003","journal-title":"Am. J. Physiol. Cell Physiol"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820577776?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820577776?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M114.597377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T09:51:06Z","timestamp":1639821066000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820577776"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S0021925820577776"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m114.597377","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]}}}