{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T07:59:11Z","timestamp":1770105551284,"version":"3.49.0"},"reference-count":100,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2015,3,1]],"date-time":"2015-03-01T00:00:00Z","timestamp":1425168000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T00:00:00Z","timestamp":1600387200000},"content-version":"vor","delay-in-days":2028,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2015,3]]},"DOI":"10.1074\/jbc.m115.636498","type":"journal-article","created":{"date-parts":[[2015,1,21]],"date-time":"2015-01-21T07:30:25Z","timestamp":1421825425000},"page":"7040-7053","source":"Crossref","is-referenced-by-count":37,"title":["Dysfunction of Platelet-derived Growth Factor Receptor \u03b1 (PDGFR\u03b1) Represses the Production of Oligodendrocytes from Arylsulfatase A-deficient Multipotential Neural Precursor Cells"],"prefix":"10.1016","volume":"290","author":[{"given":"Katarzyna C.","family":"Pituch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana L.","family":"Moyano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"Lopez-Rosas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felecia M.","family":"Marottoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guannan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenqi","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"van Breemen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan E.","family":"M\u00e5nsson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria I.","family":"Givogri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M115.636498_bib1","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1006\/dbio.1996.0142","article-title":"Determination of neuroepithelial cell fate: induction of the oligodendrocyte lineage by ventral midline cells and sonic hedgehog","volume":"177","author":"Pringle","year":"1996","journal-title":"Dev. Biol"},{"key":"10.1074\/jbc.M115.636498_bib2","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1159\/000111186","article-title":"Origins of spinal cord oligodendrocytes: possible developmental and evolutionary relationships with motor neurons","volume":"19","author":"Richardson","year":"1997","journal-title":"Dev. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib3","doi-asserted-by":"crossref","first-page":"2419","DOI":"10.1242\/dev.126.11.2419","article-title":"Sonic hedgehog signaling is required during the appearance of spinal cord oligodendrocyte precursors","volume":"126","author":"Orentas","year":"1999","journal-title":"Development"},{"key":"10.1074\/jbc.M115.636498_bib4","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1006\/mcne.2001.1026","article-title":"Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain","volume":"18","author":"Alberta","year":"2001","journal-title":"Mol. Cell Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib5","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1523\/JNEUROSCI.11-08-02477.1991","article-title":"Evidence for the ventral origin of oligodendrocyte precursors in the rat spinal cord","volume":"11","author":"Warf","year":"1991","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib6","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1242\/dev.120.5.1097","article-title":"A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development","volume":"120","author":"Barres","year":"1994","journal-title":"Development"},{"key":"10.1074\/jbc.M115.636498_bib7","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1083\/jcb.200905111","article-title":"Tapping into the glial reservoir: cells committed to remaining uncommitted","volume":"188","author":"Chong","year":"2010","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M115.636498_bib8","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1038\/333562a0","article-title":"Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture","volume":"333","author":"Raff","year":"1988","journal-title":"Nature"},{"key":"10.1074\/jbc.M115.636498_bib9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0092-8674(88)90392-3","article-title":"A role for platelet-derived growth factor in normal gliogenesis in the central nervous system","volume":"53","author":"Richardson","year":"1988","journal-title":"Cell"},{"key":"10.1074\/jbc.M115.636498_bib10","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/333560a0","article-title":"Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte\/type-2 astrocyte progenitor cell","volume":"333","author":"Noble","year":"1988","journal-title":"Nature"},{"key":"10.1074\/jbc.M115.636498_bib11","doi-asserted-by":"crossref","first-page":"9503","DOI":"10.1523\/JNEUROSCI.1531-11.2011","article-title":"PDGFR\u03b1 expression distinguishes GFAP-expressing neural stem cells from PDGF-responsive neural precursors in the adult periventricular area","volume":"31","author":"Chojnacki","year":"2011","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib12","doi-asserted-by":"crossref","first-page":"4085","DOI":"10.1242\/dev.122.12.4085","article-title":"Spinal cord oligodendrocytes develop from ventrally derived progenitor cells that express PDGF \u03b1-receptors","volume":"122","author":"Hall","year":"1996","journal-title":"Development"},{"key":"10.1074\/jbc.M115.636498_bib13","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1242\/dev.115.2.535","article-title":"PDGF receptors in the CNS: during late neurogenesis, expression of PDGF alpha receptors appears to be restricted to glial cells of the oligodendrocyte lineage","volume":"115","author":"Pringle","year":"1992","journal-title":"Development"},{"key":"10.1074\/jbc.M115.636498_bib14","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1242\/dev.126.3.457","article-title":"Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice","volume":"126","author":"Fruttiger","year":"1999","journal-title":"Development"},{"key":"10.1074\/jbc.M115.636498_bib15","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1093\/emboj\/21.8.1957","article-title":"The oligodendrocyte precursor mitogen PDGF stimulates proliferation by activation of \u03b1(v)\u03b23 integrins","volume":"21","author":"Baron","year":"2002","journal-title":"EMBO J"},{"key":"10.1074\/jbc.M115.636498_bib16","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0960-9822(02)01437-9","article-title":"Regulation of integrin growth factor interactions in oligodendrocytes by lipid raft microdomains","volume":"13","author":"Baron","year":"2003","journal-title":"Curr. Biol"},{"key":"10.1074\/jbc.M115.636498_bib17","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1042\/bst0320426","article-title":"Lipid rafts: microenvironments for integrin-growth factor interactions in neural development","volume":"32","author":"Decker","year":"2004","journal-title":"Biochem. Soc. Trans"},{"key":"10.1074\/jbc.M115.636498_bib18","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1159\/000150127","article-title":"Multipotential neural precursors transplanted into the metachromatic leukodystrophy brain fail to generate oligodendrocytes but contribute to limit brain dysfunction","volume":"30","author":"Givogri","year":"2008","journal-title":"Dev. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1046\/j.1471-4159.1998.70010308.x","article-title":"Composition and biophysical properties of myelin lipid define the neurological defects in galactocerebroside- and sulfatide-deficient mice","volume":"70","author":"Bosio","year":"1998","journal-title":"J. Neurochem"},{"key":"10.1074\/jbc.M115.636498_bib20","doi-asserted-by":"crossref","first-page":"7913","DOI":"10.1523\/JNEUROSCI.19-18-07913.1999","article-title":"Negative regulation of oligodendrocyte differentiation by galactosphingolipids","volume":"19","author":"Bansal","year":"1999","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib21","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/glia.10327","article-title":"Sulfatide is a negative regulator of oligodendrocyte differentiation: development in sulfatide-null mice","volume":"45","author":"Hirahara","year":"2004","journal-title":"Glia"},{"key":"10.1074\/jbc.M115.636498_bib22","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/42408","article-title":"Functional rafts in cell membranes","volume":"387","author":"Simons","year":"1997","journal-title":"Nature"},{"key":"10.1074\/jbc.M115.636498_bib23","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1146\/annurev.bb.14.060185.002045","article-title":"Organization of glycosphingolipids in bilayers and plasma membranes of mammalian cells","volume":"14","author":"Thompson","year":"1985","journal-title":"Annu. Rev. Biophys. Biophys. Chem"},{"key":"10.1074\/jbc.M115.636498_bib24","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1002\/jnr.22564","article-title":"Persistence of psychosine in brain lipid rafts is a limiting factor in the therapeutic recovery of a mouse model for Krabbe disease","volume":"89","author":"White","year":"2011","journal-title":"J. Neurosci. Res"},{"key":"10.1074\/jbc.M115.636498_bib25","doi-asserted-by":"crossref","first-page":"34426","DOI":"10.1074\/jbc.M111.257444","article-title":"Proteolipidic composition of exosomes changes during reticulocyte maturation","volume":"286","author":"Carayon","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M115.636498_bib26","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1182\/blood-2003-03-0871","article-title":"Lipid raft-associated protein sorting in exosomes","volume":"102","author":"de Gassart","year":"2003","journal-title":"Blood"},{"key":"10.1074\/jbc.M115.636498_bib27","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000090755","article-title":"Notch signaling in astrocytes and neuroblasts of the adult subventricular zone in health and after cortical injury","volume":"28","author":"Givogri","year":"2006","journal-title":"Dev. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib28","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/jnr.10031","article-title":"Expression and regulation of golli products of myelin basic protein gene during in vitro development of oligodendrocytes","volume":"66","author":"Givogri","year":"2001","journal-title":"J. Neurosci. Res"},{"key":"10.1074\/jbc.M115.636498_bib29","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1002\/glia.440060105","article-title":"Autocrine inhibition of mitotic activity in cultured oligodendrocyte-type-2 astrocyte (O-2A) precursor cells","volume":"6","author":"Louis","year":"1992","journal-title":"Glia"},{"key":"10.1074\/jbc.M115.636498_bib30","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipides from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M115.636498_bib31","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/jnc.12341","article-title":"Levels of plasma sulfatides C18:0 and C24:1 correlate with disease status in relapsing-remitting multiple sclerosis","volume":"127","author":"Moyano","year":"2013","journal-title":"J. Neurochem"},{"key":"10.1074\/jbc.M115.636498_bib32","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ab.2014.08.033","article-title":"Distribution of C16:0, C18:0, C24:1, and C24:0 sulfatides in central nervous system lipid rafts by quantitative ultra-high-pressure liquid chromatography tandem mass spectrometry","volume":"467","author":"Moyano","year":"2014","journal-title":"Anal. Biochem"},{"key":"10.1074\/jbc.M115.636498_bib33","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0076-6879(00)12902-7","article-title":"Purification of sphingolipid classes by solid-phase extraction with aminopropyl and weak cation exchanger cartridges","volume":"312","author":"Bodennec","year":"2000","journal-title":"Methods Enzymol"},{"key":"10.1074\/jbc.M115.636498_bib34","doi-asserted-by":"crossref","first-page":"43108","DOI":"10.1074\/jbc.M112.404467","article-title":"The exosome secretory pathway transports amyloid precursor protein carboxyl-terminal fragments from the cell into the brain extracellular space","volume":"287","author":"Perez-Gonzalez","year":"2012","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M115.636498_bib35","series-title":"Curr. Protoc. Cell Biol","article-title":"Isolation and characterization of exosomes from cell culture supernatants and biological fluids","author":"Thery","year":"2006"},{"key":"10.1074\/jbc.M115.636498_bib36","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.ymthe.2005.06.438","article-title":"Axons mediate the distribution of arylsulfatase A within the mouse hippocampus upon gene delivery","volume":"12","author":"Luca","year":"2005","journal-title":"Mol. Ther"},{"key":"10.1074\/jbc.M115.636498_bib37","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1073\/pnas.62.3.887","article-title":"Metachromatic leukodystrophy: arylsulfatase-A deficiency in skin fibroblast cultures","volume":"62","author":"Porter","year":"1969","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.636498_bib38","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/j.1460-9568.2005.03891.x","article-title":"Delay of myelin formation in arylsulphatase A-deficient mice","volume":"21","author":"Yaghootfam","year":"2005","journal-title":"Eur. J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib39","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/0092-8674(88)90392-3","article-title":"A role for platelet-derived growth factor in normal gliogenesis in the central nervous system","volume":"53","author":"Richardson","year":"1988","journal-title":"Cell"},{"key":"10.1074\/jbc.M115.636498_bib40","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/j.1749-6632.1991.tb49048.x","article-title":"A role for fibroblast growth factor in oligodendrocyte development","volume":"638","author":"McKinnon","year":"1991","journal-title":"Ann. N. Y. Acad. Sci"},{"key":"10.1074\/jbc.M115.636498_bib41","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1006\/mcne.1996.0590","article-title":"PDGF-alpha receptor and myelin basic protein mRNAs are not coexpressed by oligodendrocytes in vivo: a double in situ hybridization study in the anterior medullary velum of the neonatal rat","volume":"8","author":"Butt","year":"1997","journal-title":"Mol. Cell Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib42","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1046\/j.1471-4159.1996.66051986.x","article-title":"Activation of mitogen-activated protein kinases in oligodendrocytes","volume":"66","author":"Bhat","year":"1996","journal-title":"J. Neurochem"},{"key":"10.1074\/jbc.M115.636498_bib43","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1006\/mcne.1999.0827","article-title":"PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: regulation of proliferation and differentiation by multiple intracellular signaling pathways","volume":"15","author":"Baron","year":"2000","journal-title":"Mol. Cell Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib44","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S1534-5807(01)00103-4","article-title":"An allelic series at the PDGF\u03b1R locus indicates unequal contributions of distinct signaling pathways during development","volume":"2","author":"Klinghoffer","year":"2002","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.M115.636498_bib45","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.devcel.2008.07.001","article-title":"The garden of forking paths: recycling, signaling, and degradation","volume":"15","author":"Gonzalez-Gaitan","year":"2008","journal-title":"Dev. Cell"},{"key":"10.1074\/jbc.M115.636498_bib46","doi-asserted-by":"crossref","first-page":"1610","DOI":"10.1016\/j.yexcr.2008.10.014","article-title":"Ubiquitin in trafficking: the network at work","volume":"315","author":"Acconcia","year":"2009","journal-title":"Exp. Cell Res"},{"key":"10.1074\/jbc.M115.636498_bib47","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.semcdb.2011.11.002","article-title":"Membrane trafficking and signaling: two sides of the same coin","volume":"23","author":"Gonnord","year":"2012","journal-title":"Semin. Cell Dev. Biol"},{"key":"10.1074\/jbc.M115.636498_bib48","first-page":"177","article-title":"Reticulocyte membrane remodeling: contribution of the exosome pathway","volume":"17","author":"Blanc","year":"2010","journal-title":"Curr. Opin. Hematol"},{"key":"10.1074\/jbc.M115.636498_bib49","doi-asserted-by":"crossref","first-page":"228","DOI":"10.3389\/fphys.2012.00228","article-title":"Role of exosomes\/microvesicles in the nervous system and use in emerging therapies","volume":"3","author":"Lai","year":"2012","journal-title":"Front. Physiol"},{"key":"10.1074\/jbc.M115.636498_bib50","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1083\/jcb.200509022","article-title":"Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites","volume":"172","author":"Trajkovic","year":"2006","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M115.636498_bib51","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1074\/jbc.M110.190009","article-title":"Inhibition of myelin membrane sheath formation by oligodendrocyte-derived exosome-like vesicles","volume":"286","author":"Bakhti","year":"2011","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M115.636498_bib52","doi-asserted-by":"crossref","first-page":"6068","DOI":"10.1523\/JNEUROSCI.5597-08.2009","article-title":"Psychosine accumulates in membrane microdomains in the brain of Krabbe patients, disrupting the raft architecture","volume":"29","author":"White","year":"2009","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib53","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1086\/498652","article-title":"The role of mannosylated enzyme and the mannose receptor in enzyme replacement therapy","volume":"77","author":"Du","year":"2005","journal-title":"Am. J. Hum. Genet"},{"key":"10.1074\/jbc.M115.636498_bib54","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1523\/JNEUROSCI.4366-05.2006","article-title":"Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy","volume":"26","author":"Givogri","year":"2006","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib55","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1083\/jcb.85.3.890","article-title":"Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue","volume":"85","author":"McCarthy","year":"1980","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M115.636498_bib56","doi-asserted-by":"crossref","first-page":"13280","DOI":"10.1073\/pnas.93.23.13280","article-title":"Functional breakdown of the lipid bilayer of the myelin membrane in central and peripheral nervous system by disrupted galactocerebroside synthesis","volume":"93","author":"Bosio","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.636498_bib57","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0092-8674(00)80093-8","article-title":"Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability","volume":"86","author":"Coetzee","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M115.636498_bib58","doi-asserted-by":"crossref","first-page":"4307","DOI":"10.1523\/JNEUROSCI.08-11-04307.1988","article-title":"Antibody to galactocerebroside alters organization of oligodendroglial membrane sheets in culture","volume":"8","author":"Dyer","year":"1988","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib59","doi-asserted-by":"crossref","first-page":"6181","DOI":"10.1073\/pnas.86.16.6181","article-title":"Reversible inhibition of oligodendrocyte progenitor differentiation by a monoclonal antibody against surface galactolipids","volume":"86","author":"Bansal","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.636498_bib60","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1111\/j.1651-2227.2003.tb00225.x","article-title":"Metachromatic leukodystrophy: consequences of sulphatide accumulation","volume":"92","author":"Gieselmann","year":"2003","journal-title":"Acta Paediatr. Suppl"},{"key":"10.1074\/jbc.M115.636498_bib61","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0012-1606(81)80006-1","article-title":"Quantitative measurement of in vivo sulfatide metabolism during development of the mouse brain: evidence for a large rapidly degradable sulfatide pool","volume":"83","author":"Burkart","year":"1981","journal-title":"Dev. Biol"},{"key":"10.1074\/jbc.M115.636498_bib62","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/j.1600-0854.2004.0181.x","article-title":"Lipids as targeting signals: lipid rafts and intracellular trafficking","volume":"5","author":"Helms","year":"2004","journal-title":"Traffic"},{"key":"10.1074\/jbc.M115.636498_bib63","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/nrm2977","article-title":"Revitalizing membrane rafts: new tools and insights","volume":"11","author":"Simons","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"10.1074\/jbc.M115.636498_bib64","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1242\/jcs.1991.Supplement_15.16","article-title":"Growth factors and transcription factors in oligodendrocyte development","volume":"15","author":"Collarini","year":"1991","journal-title":"J. Cell Sci. Suppl"},{"key":"10.1074\/jbc.M115.636498_bib65","doi-asserted-by":"crossref","first-page":"3411","DOI":"10.1083\/jcb.109.6.3411","article-title":"PDGF and intracellular signaling in the timing of oligodendrocyte differentiation","volume":"109","author":"Hart","year":"1989","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M115.636498_bib66","doi-asserted-by":"crossref","first-page":"12","DOI":"10.2174\/1874091X00701010012","article-title":"Lipid rafts and caveolae in signaling by growth factor receptors","volume":"1","author":"de Laurentiis","year":"2007","journal-title":"Open Biochem. J"},{"key":"10.1074\/jbc.M115.636498_bib67","doi-asserted-by":"crossref","first-page":"11239","DOI":"10.1074\/jbc.M107756200","article-title":"Overexpression of ganglioside GM1 results in the dispersion of platelet-derived growth factor receptor from glycolipid-enriched microdomains and in the suppression of cell growth signals","volume":"277","author":"Mitsuda","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M115.636498_bib68","doi-asserted-by":"crossref","first-page":"7622","DOI":"10.1523\/JNEUROSCI.20-20-07622.2000","article-title":"Akt-mediated survival of oligodendrocytes induced by neuregulins","volume":"20","author":"Flores","year":"2000","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib69","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/ncb2735","article-title":"Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain","volume":"15","author":"Rafalski","year":"2013","journal-title":"Nat. Cell Biol"},{"key":"10.1074\/jbc.M115.636498_bib70","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/S0960-9822(02)00973-9","article-title":"Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1","volume":"12","author":"Hill","year":"2002","journal-title":"Curr. Biol"},{"key":"10.1074\/jbc.M115.636498_bib71","doi-asserted-by":"crossref","first-page":"e118","DOI":"10.1038\/bcj.2013.15","article-title":"Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma","volume":"3","author":"Reis-Sobreiro","year":"2013","journal-title":"Blood Cancer J"},{"key":"10.1074\/jbc.M115.636498_bib72","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1083\/jcb.132.6.1011","article-title":"Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes","volume":"132","author":"Futter","year":"1996","journal-title":"J. Cell Biol"},{"key":"10.1074\/jbc.M115.636498_bib73","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0014-5793(94)00282-7","article-title":"Intracellular trafficking of glycosphingolipids: role of sphingolipid activator proteins in the topology of endocytosis and lysosomal digestion","volume":"346","author":"Sandhoff","year":"1994","journal-title":"FEBS Lett"},{"key":"10.1074\/jbc.M115.636498_bib74","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/nri855","article-title":"Exosomes: composition, biogenesis and function","volume":"2","author":"Th\u00e9ry","year":"2002","journal-title":"Nat. Rev. Immunol"},{"key":"10.1074\/jbc.M115.636498_bib75","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1242\/jcs.110.16.1867","article-title":"Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation","volume":"110","author":"Vidal","year":"1997","journal-title":"J. Cell Sci"},{"key":"10.1074\/jbc.M115.636498_bib76","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1126\/science.1153124","article-title":"Ceramide triggers budding of exosome vesicles into multivesicular endosomes","volume":"319","author":"Trajkovic","year":"2008","journal-title":"Science"},{"key":"10.1074\/jbc.M115.636498_bib77","doi-asserted-by":"crossref","first-page":"2667","DOI":"10.1007\/s00018-011-0689-3","article-title":"Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles","volume":"68","author":"Gy\u00f6rgy","year":"2011","journal-title":"Cell Mol. Life Sci"},{"key":"10.1074\/jbc.M115.636498_bib78","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1126\/science.1155750","article-title":"Cell biology: no ESCRTs for exosomes","volume":"319","author":"Marsh","year":"2008","journal-title":"Science"},{"key":"10.1074\/jbc.M115.636498_bib79","doi-asserted-by":"crossref","first-page":"26279","DOI":"10.1074\/jbc.M110.134775","article-title":"Exosome secretion ameliorates lysosomal storage of cholesterol in Niemann-Pick type C disease","volume":"285","author":"Strauss","year":"2010","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M115.636498_bib80","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1111\/j.1600-0854.2011.01225.x","article-title":"Exosome secretion: molecular mechanisms and roles in immune responses","volume":"12","author":"Bobrie","year":"2011","journal-title":"Traffic"},{"key":"10.1074\/jbc.M115.636498_bib81","doi-asserted-by":"crossref","first-page":"88","DOI":"10.4161\/cib.18452","article-title":"Intracellular signaling controlled by the endosomal-exosomal pathway","volume":"5","author":"Verweij","year":"2012","journal-title":"Commun Integr. Biol"},{"key":"10.1074\/jbc.M115.636498_bib82","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1002\/prca.200700522","article-title":"Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?","volume":"1","author":"Kr\u00e4mer-Albers","year":"2007","journal-title":"Proteomics Clin. Appl"},{"key":"10.1074\/jbc.M115.636498_bib83","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/361258a0","article-title":"Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons","volume":"361","author":"Barres","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M115.636498_bib84","doi-asserted-by":"crossref","first-page":"9887","DOI":"10.1073\/pnas.93.18.9887","article-title":"Induction of myelination in the central nervous system by electrical activity","volume":"93","author":"Demerens","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.636498_bib85","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/9780470032244.ch12","article-title":"Nerve impulses regulate myelination through purinergic signalling","volume":"276","author":"Fields","year":"2006","journal-title":"Novartis Found. Symp"},{"key":"10.1074\/jbc.M115.636498_bib86","doi-asserted-by":"crossref","first-page":"1252304","DOI":"10.1126\/science.1252304","article-title":"Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain","volume":"344","author":"Gibson","year":"2014","journal-title":"Science"},{"key":"10.1074\/jbc.M115.636498_bib87","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.neuron.2006.02.006","article-title":"Astrocytes promote myelination in response to electrical impulses","volume":"49","author":"Ishibashi","year":"2006","journal-title":"Neuron"},{"key":"10.1074\/jbc.M115.636498_bib88","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1038\/nn.3469","article-title":"M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination","volume":"16","author":"Miron","year":"2013","journal-title":"Nat. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib89","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/glia.1085","article-title":"Macrophage depletion impairs oligodendrocyte remyelination following lysolecithin-induced demyelination","volume":"35","author":"Kotter","year":"2001","journal-title":"Glia"},{"key":"10.1074\/jbc.M115.636498_bib90","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1093\/brain\/awn334","article-title":"Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling","volume":"132","author":"Baer","year":"2009","journal-title":"Brain"},{"key":"10.1074\/jbc.M115.636498_bib91","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/j.1600-0404.2011.01554.x","article-title":"Myelin glycosphingolipid immunoreactivity and CSF levels in multiple sclerosis","volume":"125","author":"Haghighi","year":"2012","journal-title":"Acta Neurol. Scand"},{"key":"10.1074\/jbc.M115.636498_bib92","doi-asserted-by":"crossref","first-page":"6825","DOI":"10.1523\/JNEUROSCI.6239-09.2010","article-title":"MAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord trauma","volume":"30","author":"Cafferty","year":"2010","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib93","doi-asserted-by":"crossref","first-page":"12432","DOI":"10.1523\/JNEUROSCI.0895-10.2010","article-title":"Oligodendrocyte-myelin glycoprotein and Nogo negatively regulate activity-dependent synaptic plasticity","volume":"30","author":"Raiker","year":"2010","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.636498_bib94","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1161\/01.RES.87.12.1172","article-title":"The \u03b22-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through Gi-dependent coupling to phosphatidylinositol 3\u2032-kinase","volume":"87","author":"Chesley","year":"2000","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M115.636498_bib95","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00216-011-4802-0","article-title":"Imaging of complex sulfatides SM3 and SB1a in mouse kidney using MALDI-TOF\/TOF mass spectrometry","volume":"401","author":"Marsching","year":"2011","journal-title":"Anal. Bioanal. Chem"},{"key":"10.1074\/jbc.M115.636498_bib96","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/jb\/mvs080","article-title":"Sulfatide negatively regulates the fusion process of human parainfluenza virus type 3","volume":"152","author":"Takahashi","year":"2012","journal-title":"J. Biochem"},{"key":"10.1074\/jbc.M115.636498_bib97","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1023\/B:GLYC.0000004012.14438.e6","article-title":"Sulfatide is associated with insulin granules and located to microdomains of a cultured \u03b2 cell line","volume":"19","author":"Blomqvist","year":"2002","journal-title":"Glycoconj. J"},{"key":"10.1074\/jbc.M115.636498_bib98","first-page":"2917","article-title":"Accumulation of highly acidic sulfated glycosphingolipids in human hepatocellular carcinoma defined by a series of monoclonal antibodies","volume":"50","author":"Hiraiwa","year":"1990","journal-title":"Cancer Res"},{"key":"10.1074\/jbc.M115.636498_bib99","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0304-3835(91)90155-B","article-title":"Distinctive glycolipid patterns in Wilms' tumor and renal cell carcinoma","volume":"57","author":"Sakakibara","year":"1991","journal-title":"Cancer Lett"},{"key":"10.1074\/jbc.M115.636498_bib100","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/(SICI)1097-0142(19960701)78:1<43::AID-CNCR8>3.0.CO;2-I","article-title":"Sulfatides as a predictive factor of lymph node metastasis in patients with colorectal adenocarcinoma","volume":"78","author":"Morichika","year":"1996","journal-title":"Cancer"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820767815?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820767815?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M115.636498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T18:01:39Z","timestamp":1717696899000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820767815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3]]},"references-count":100,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["S0021925820767815"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m115.636498","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2015,3]]}}}