{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T10:09:26Z","timestamp":1786961366211,"version":"build-2736575974"},"reference-count":72,"publisher":"Elsevier BV","issue":"31","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":1889,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1074\/jbc.m115.655092","type":"journal-article","created":{"date-parts":[[2015,6,10]],"date-time":"2015-06-10T16:35:02Z","timestamp":1433954102000},"page":"19273-19286","update-policy":"https:\/\/doi.org\/10.1074\/jbc.f110.005975","source":"Crossref","is-referenced-by-count":45,"title":["Evidence That Antibiotics Bind to Human Mitochondrial Ribosomal RNA Has Implications for Aminoglycoside Toxicity"],"prefix":"10.1016","volume":"290","author":[{"given":"Seoyeon","family":"Hong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly A.","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn D.","family":"Fanning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn L.","family":"Sarachan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyla M.","family":"Frohlich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul F.","family":"Agris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M115.655092_bib1","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/embo-reports\/kve062","article-title":"Structural basis for selectivity and toxicity of ribosomal antibiotics","volume":"2","author":"B\u00f6ttger","year":"2001","journal-title":"EMBO Rep"},{"key":"10.1074\/jbc.M115.655092_bib2","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1006\/jmbi.2000.4420","article-title":"Structural origins of aminoglycoside specificity for prokaryotic ribosomes","volume":"306","author":"Lynch","year":"2001","journal-title":"J. Mol. Biol"},{"key":"10.1074\/jbc.M115.655092_bib3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1021\/cr0301088","article-title":"Molecular insights into aminoglycoside action and resistance","volume":"105","author":"Magnet","year":"2005","journal-title":"Chem. Rev"},{"key":"10.1074\/jbc.M115.655092_bib4","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/327389a0","article-title":"Interaction of antibiotics with functional sites in 16S ribosomal RNA","volume":"327","author":"Moazed","year":"1987","journal-title":"Nature"},{"key":"10.1074\/jbc.M115.655092_bib5","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1002\/j.1460-2075.1991.tb07863.x","article-title":"Interaction of antibiotics with A- and P-site-specific bases in 16S ribosomal RNA","volume":"10","author":"Woodcock","year":"1991","journal-title":"EMBO J"},{"key":"10.1074\/jbc.M115.655092_bib6","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1021\/cb3005116","article-title":"Aminoglycoside antibiotics in the 21st century","volume":"8","author":"Becker","year":"2013","journal-title":"ACS Chem. Biol"},{"key":"10.1074\/jbc.M115.655092_bib7","doi-asserted-by":"crossref","first-page":"3312","DOI":"10.1016\/S0021-9258(18)93308-9","article-title":"Misreading of ribonucleic acid code words induced by aminoglycoside antibiotics. The effect of drug concentration","volume":"243","author":"Davies","year":"1968","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M115.655092_bib8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1146\/annurev.biochem.74.061903.155440","article-title":"Structural insights into translational fidelity","volume":"74","author":"Ogle","year":"2005","journal-title":"Annu. Rev. Biochem"},{"key":"10.1074\/jbc.M115.655092_bib9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/jac\/4.4.309","article-title":"Apramycin, a new aminocyclitol antibiotic. I. In vitro microbiological studies","volume":"4","author":"Walton","year":"1978","journal-title":"J. Antimicrob. Chemother"},{"key":"10.1074\/jbc.M115.655092_bib10","first-page":"60","article-title":"Critical tests of hygromycin B as an ascaricide of swine","volume":"50","author":"Kelley","year":"1960","journal-title":"Cornell Vet"},{"key":"10.1074\/jbc.M115.655092_bib11","first-page":"570","article-title":"Efficacy of lincomycin and spectinomycin on canine pathogens","volume":"25","author":"Hamdy","year":"1975","journal-title":"Lab. Anim. Sci"},{"key":"10.1074\/jbc.M115.655092_bib12","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.bcmd.2006.11.006","article-title":"Apramycin recognition by the human ribosomal decoding site","volume":"38","author":"Hermann","year":"2007","journal-title":"Blood Cells Mol. Dis"},{"key":"10.1074\/jbc.M115.655092_bib13","doi-asserted-by":"crossref","first-page":"4458","DOI":"10.1093\/nar\/gkq159","article-title":"A model for the study of ligand binding to the ribosomal RNA helix h44","volume":"38","author":"Dibrov","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M115.655092_bib14","doi-asserted-by":"crossref","first-page":"3079","DOI":"10.1523\/JNEUROSCI.3430-12.2013","article-title":"A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity","volume":"33","author":"Francis","year":"2013","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M115.655092_bib15","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1128\/AAC.43.5.1003","article-title":"Aminoglycosides: nephrotoxicity","volume":"43","author":"Mingeot-Leclercq","year":"1999","journal-title":"Antimicrob. Agents Chemother"},{"key":"10.1074\/jbc.M115.655092_bib16","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1038\/ki.2012.328","article-title":"In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury","volume":"83","author":"Hall","year":"2013","journal-title":"Kidney Int"},{"key":"10.1074\/jbc.M115.655092_bib17","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/0378-5955(94)90232-1","article-title":"Ototoxicity in vitro: effects of neomycin, gentamicin, dihydrostreptomycin, amikacin, spectinomycin, neamine, spermine and poly-l-lysine","volume":"73","author":"Kotecha","year":"1994","journal-title":"Hear. Res"},{"key":"10.1074\/jbc.M115.655092_bib18","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/nsmb1271","article-title":"Structural basis for aminoglycoside inhibition of bacterial ribosome recycling","volume":"14","author":"Borovinskaya","year":"2007","journal-title":"Nat. Struct. Mol. Biol"},{"key":"10.1074\/jbc.M115.655092_bib19","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1038\/nsmb.2360","article-title":"Allosteric control of the ribosome by small-molecule antibiotics","volume":"19","author":"Wang","year":"2012","journal-title":"Nat. Struct. Mol. Biol"},{"key":"10.1074\/jbc.M115.655092_bib20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1471-2105-3-2","article-title":"The comparative RNA web (CRW) site: an online database of comparative sequence and structure information for ribosomal, intron, and other RNAs","volume":"3","author":"Cannone","year":"2002","journal-title":"BMC Bioinformatics"},{"key":"10.1074\/jbc.M115.655092_bib21","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1126\/science.1060089","article-title":"Crystal structure of the ribosome at 5.5 \u00c5 resolution","volume":"292","author":"Yusupov","year":"2001","journal-title":"Science"},{"key":"10.1074\/jbc.M115.655092_bib22","doi-asserted-by":"crossref","first-page":"8900","DOI":"10.1073\/pnas.0401904101","article-title":"Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications","volume":"101","author":"Agrawal","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.655092_bib23","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1056\/NEJM198005153022002","article-title":"Double-blind comparison of the nephrotoxicity and auditory toxicity of gentamicin and tobramycin","volume":"302","author":"Smith","year":"1980","journal-title":"N. Engl. J. Med"},{"key":"10.1074\/jbc.M115.655092_bib24","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1111\/j.1749-6632.1966.tb43018.x","article-title":"Toxicity of kanamycin in adults","volume":"132","author":"Finegold","year":"1966","journal-title":"Ann. N. Y. Acad. Sci"},{"key":"10.1074\/jbc.M115.655092_bib25","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1177\/000348947908800107","article-title":"Gentamicin vestibulotoxicity: long term disability","volume":"88","author":"Dayal","year":"1979","journal-title":"Ann. Otol. Rhinol. Laryngol"},{"key":"10.1074\/jbc.M115.655092_bib26","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1097\/00005537-200110000-00025","article-title":"Aminoglycoside ototoxicity: a human temporal bone study","volume":"111","author":"Hinojosa","year":"2001","journal-title":"Laryngoscope"},{"key":"10.1074\/jbc.M115.655092_bib27","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/00005131-200303000-00010","article-title":"Gentamicin may have an adverse effect on osteogenesis","volume":"17","author":"Isefuku","year":"2003","journal-title":"J. Orthop. Trauma"},{"key":"10.1074\/jbc.M115.655092_bib28","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1749-6632.1958.tb54692.x","article-title":"Pharmacological studies with kanamycin","volume":"76","author":"Tisch","year":"1958","journal-title":"Ann. N. Y. Acad. Sci"},{"key":"10.1074\/jbc.M115.655092_bib29","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.toxlet.2009.12.003","article-title":"Ototoxic drugs: difference in sensitivity between mice and guinea pigs","volume":"193","author":"Poirrier","year":"2010","journal-title":"Toxicol. Lett"},{"key":"10.1074\/jbc.M115.655092_bib30","series-title":"Infectious Diseases of the Dog and Cat","first-page":"515","article-title":"Botulism","author":"Barsanti","year":"1990"},{"key":"10.1074\/jbc.M115.655092_bib31","doi-asserted-by":"crossref","first-page":"3094","DOI":"10.1093\/nar\/gkp1253","article-title":"Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA","volume":"38","author":"Scheunemann","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M115.655092_bib32","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1093\/nar\/28.10.2075","article-title":"Unique structural and stabilizing roles for the individual pseudouridine residues in the 1920 region of Escherichia coli 23S rRNA","volume":"28","author":"Meroueh","year":"2000","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M115.655092_bib33","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1261\/rna.2320605","article-title":"Effects of nucleotide substitution and modification on the stability and structure of helix 69 from 28S rRNA","volume":"11","author":"Sumita","year":"2005","journal-title":"RNA"},{"key":"10.1074\/jbc.M115.655092_bib34","doi-asserted-by":"crossref","first-page":"3543","DOI":"10.1093\/nar\/27.17.3543","article-title":"Structural and functional roles of the N1- and N3-protons of \u03a8 at tRNA's position 39","volume":"27","author":"Yarian","year":"1999","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M115.655092_bib35","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1006\/jmbi.1998.2297","article-title":"Stabilization of the anticodon stem-loop of tRNALys,3 by an A+-C base-pair and by pseudouridine","volume":"285","author":"Durant","year":"1999","journal-title":"J. Mol. Biol"},{"key":"10.1074\/jbc.M115.655092_bib36","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1128\/AAC.47.5.1496-1502.2003","article-title":"Role of 16S rRNA helix 44 in ribosomal resistance to hygromycin B","volume":"47","author":"Pfister","year":"2003","journal-title":"Antimicrob. Agents Chemother"},{"key":"10.1074\/jbc.M115.655092_bib37","doi-asserted-by":"crossref","first-page":"16820","DOI":"10.1073\/pnas.1309392110","article-title":"High-resolution reversible folding of hyperstable RNA tetraloops using molecular dynamics simulations","volume":"110","author":"Chen","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.655092_bib38","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1128\/mr.58.1.10-26.1994","article-title":"Lessons from an evolving rRNA: 16S and 23S rRNA structures from a comparative perspective","volume":"58","author":"Gutell","year":"1994","journal-title":"Microbiol. Rev"},{"key":"10.1074\/jbc.M115.655092_bib39","doi-asserted-by":"crossref","first-page":"8467","DOI":"10.1073\/pnas.87.21.8467","article-title":"Architecture of ribosomal RNA: constraints on the sequence of \u201ctetra-loops\u201d","volume":"87","author":"Woese","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.655092_bib40","doi-asserted-by":"crossref","first-page":"3244","DOI":"10.1073\/pnas.0707265105","article-title":"Mitochondrial deafness alleles confer misreading of the genetic code","volume":"105","author":"Hobbie","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.655092_bib41","doi-asserted-by":"crossref","first-page":"14077","DOI":"10.1021\/bi9615710","article-title":"Investigation of the structural basis for thermodynamic stabilities of tandem GU mismatches: solution structure of (rGAGGUCUC)2 by two-dimensional NMR and simulated annealing","volume":"35","author":"McDowell","year":"1996","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M115.655092_bib42","series-title":"Curr. Protoc. Nucleic Acid Chem","article-title":"Characterization of tertiary folding of RNA by circular dichroism and urea","author":"Sosnick","year":"2001"},{"key":"10.1074\/jbc.M115.655092_bib43","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/jmra.1995.1047","article-title":"Water suppression that works: excitation sculpting using arbitrary wave-forms and pulsed-field gradients","volume":"112","author":"Hwang","year":"1995","journal-title":"J. Magn. Reson. Series A"},{"key":"10.1074\/jbc.M115.655092_bib44","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00197809","article-title":"NMRPipe: a multidimensional spectral processing system based on UNIX pipes","volume":"6","author":"Delaglio","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"10.1074\/jbc.M115.655092_bib45","first-page":"313","article-title":"Using NMRView to visualize and analyze the NMR spectra of macromolecules","volume":"278","author":"Johnson","year":"2004","journal-title":"Methods Mol. Biol"},{"key":"10.1074\/jbc.M115.655092_bib46","doi-asserted-by":"crossref","first-page":"7695","DOI":"10.1021\/bi020130f","article-title":"Thermodynamics of aminoglycoside-rRNA recognition: the binding of neomycin-class aminoglycosides to the A site of 16S rRNA","volume":"41","author":"Kaul","year":"2002","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M115.655092_bib47","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1021\/cr0681546","article-title":"Targeting RNA with small molecules","volume":"108","author":"Thomas","year":"2008","journal-title":"Chem. Rev"},{"key":"10.1074\/jbc.M115.655092_bib48","series-title":"Circular Dichroism and Linear Dichroism","first-page":"25","article-title":"CD of polynucleotides: DNA and RNA","author":"Rodger","year":"1997"},{"key":"10.1074\/jbc.M115.655092_bib49","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms4112","article-title":"4\u2032-O-substitutions determine selectivity of aminoglycoside antibiotics","volume":"5","author":"Perez-Fernandez","year":"2014","journal-title":"Nat. Commun"},{"key":"10.1074\/jbc.M115.655092_bib50","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1017\/S1355838299982304","article-title":"Crystal structure of acceptor stem of tRNA(Ala) from Escherichia coli shows unique G\u00b7U wobble base pair at 1.16 \u00c5 resolution","volume":"5","author":"Mueller","year":"1999","journal-title":"RNA"},{"key":"10.1074\/jbc.M115.655092_bib51","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1021\/bi962095g","article-title":"Specificity of aminoglycoside binding to RNA constructs derived from the 16S rRNA decoding region and the HIV-RRE activator region","volume":"36","author":"Wang","year":"1997","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M115.655092_bib52","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1534\/genetics.112.141267","article-title":"Mitochondrial protein synthesis, import, and assembly","volume":"192","author":"Fox","year":"2012","journal-title":"Genetics"},{"key":"10.1074\/jbc.M115.655092_bib53","series-title":"Molecular Biology of the Cell","first-page":"819","article-title":"The genetic systems of mitochondria and plastids","author":"Walter","year":"2002"},{"key":"10.1074\/jbc.M115.655092_bib54","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF00986960","article-title":"Protein synthesis in mitochondria","volume":"19","author":"Pel","year":"1994","journal-title":"Mol. Biol. Rep"},{"key":"10.1074\/jbc.M115.655092_bib55","doi-asserted-by":"crossref","first-page":"5464","DOI":"10.1073\/pnas.96.10.5464","article-title":"Plant ribosome recycling factor homologue is a chloroplastic protein and is bactericidal in Escherichia coli carrying temperature-sensitive ribosome recycling factor","volume":"96","author":"Rolland","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.655092_bib56","doi-asserted-by":"crossref","first-page":"4218","DOI":"10.1093\/nar\/gkg449","article-title":"Temperature-sensitive mutation in yeast mitochondrial ribosome recycling factor (RRF)","volume":"31","author":"Teyssier","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"10.1074\/jbc.M115.655092_bib57","doi-asserted-by":"crossref","first-page":"10854","DOI":"10.1073\/pnas.1006247107","article-title":"Ribosome recycling step in yeast cytoplasmic protein synthesis is catalyzed by eEF3 and ATP","volume":"107","author":"Kurata","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.655092_bib58","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1093\/emboj\/17.4.1141","article-title":"Evidence for in vivo ribosome recycling, the fourth step in protein biosynthesis","volume":"17","author":"Janosi","year":"1998","journal-title":"EMBO J"},{"key":"10.1074\/jbc.M115.655092_bib59","doi-asserted-by":"crossref","first-page":"4249","DOI":"10.1073\/pnas.91.10.4249","article-title":"Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth","volume":"91","author":"Janosi","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M115.655092_bib60","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0092-8674(02)00938-8","article-title":"Orientation of ribosome recycling factor in the ribosome from directed hydroxyl radical probing","volume":"111","author":"Lancaster","year":"2002","journal-title":"Cell"},{"key":"10.1074\/jbc.M115.655092_bib61","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1126\/science.1258026","article-title":"Structure of the large ribosomal subunit from human mitochondria","volume":"346","author":"Brown","year":"2014","journal-title":"Science"},{"key":"10.1074\/jbc.M115.655092_bib62","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.cell.2006.08.032","article-title":"Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements","volume":"126","author":"Korostelev","year":"2006","journal-title":"Cell"},{"key":"10.1074\/jbc.M115.655092_bib63","first-page":"54","article-title":"Symptomatic hypomagnesemia associated with gentamicin therapy","volume":"9","author":"Kes","year":"1990","journal-title":"Magnes. Trace Elem"},{"key":"10.1074\/jbc.M115.655092_bib64","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1007\/s00467-003-1161-x","article-title":"Association of hypocalcemia with a change in gentamicin administration in neonates","volume":"18","author":"Jackson","year":"2003","journal-title":"Pediatr. Nephrol"},{"key":"10.1074\/jbc.M115.655092_bib65","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1034\/j.1600-0536.2001.440107-21.x","article-title":"Allergic contact dermatitis from gentamicin in eyedrops, with cross-reactivity to kanamycin but not neomycin","volume":"44","author":"S\u00e1nchez-P\u00e9rez","year":"2001","journal-title":"Contact Dermatitis"},{"key":"10.1074\/jbc.M115.655092_bib66","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1034\/j.1398-9995.2003.23710_5.x","article-title":"Gentamicin-induced anaphylaxis","volume":"58","author":"Schulze","year":"2003","journal-title":"Allergy"},{"key":"10.1074\/jbc.M115.655092_bib67","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD004496.pub2","article-title":"Intraventricular antibiotics for bacterial meningitis in neonates","author":"Shah","year":"2004","journal-title":"Cochrane Database Syst. Rev"},{"key":"10.1074\/jbc.M115.655092_bib68","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1097\/00007611-197510000-00025","article-title":"Acute toxic psychosis associated with gentamicin therapy","volume":"68","author":"Kane","year":"1975","journal-title":"South. Med. J"},{"key":"10.1074\/jbc.M115.655092_bib69","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/S0092-8674(00)00216-6","article-title":"The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit","volume":"103","author":"Brodersen","year":"2000","journal-title":"Cell"},{"key":"10.1074\/jbc.M115.655092_bib70","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/S0749-0720(15)31258-5","article-title":"Anthelmintics for swine","volume":"2","author":"Biehl","year":"1986","journal-title":"Vet. Clin. North Am. Food Anim. Pract"},{"key":"10.1074\/jbc.M115.655092_bib71","doi-asserted-by":"crossref","first-page":"5112","DOI":"10.1128\/AAC.49.12.5112-5118.2005","article-title":"Analysis of the contribution of individual substituents in 4,6-aminoglycoside-ribosome interaction","volume":"49","author":"Hobbie","year":"2005","journal-title":"Antimicrob. Agents Chemother"},{"key":"10.1074\/jbc.M115.655092_bib72","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1126\/science.1117230","article-title":"Structures of the bacterial ribosome at 3.5 \u00c5 resolution","volume":"310","author":"Schuwirth","year":"2005","journal-title":"Science"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820422963?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820422963?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M115.655092","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T11:53:55Z","timestamp":1641297235000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820422963"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":72,"journal-issue":{"issue":"31","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["S0021925820422963"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m115.655092","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2015,7]]}}}