{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T15:23:08Z","timestamp":1791386588765,"version":"4.3.3"},"reference-count":69,"publisher":"Elsevier BV","issue":"19","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T00:00:00Z","timestamp":1598832000000},"content-version":"vor","delay-in-days":1218,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MC_U105663142"],"award-info":[{"award-number":["MC_U105663142"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["110159\/Z\/15\/Z"],"award-info":[{"award-number":["110159\/Z\/15\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["110158\/Z\/15\/Z"],"award-info":[{"award-number":["110158\/Z\/15\/Z"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","award":["BB\/I012826\/1"],"award-info":[{"award-number":["BB\/I012826\/1"]}],"id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Consejo Nacional de Ciencia y Technolog?a","award":["Studentship to CB-G"],"award-info":[{"award-number":["Studentship to CB-G"]}]},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","award":["Atip-Avenir grant"],"award-info":[{"award-number":["Atip-Avenir grant"]}],"id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1074\/jbc.m117.784678","type":"journal-article","created":{"date-parts":[[2017,3,21]],"date-time":"2017-03-21T00:10:11Z","timestamp":1490055011000},"page":"7761-7773","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA"],"prefix":"10.1016","volume":"292","author":[{"given":"Sabine","family":"Arndt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos D.","family":"Baeza-Garza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Logan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiziana","family":"Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Wedmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy A.","family":"Prime","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack L.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kourosh","family":"Saeb-Parsy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Krieg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milos R.","family":"Filipovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard C.","family":"Hartley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M117.784678_bib1","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1523\/JNEUROSCI.16-03-01066.1996","article-title":"The possible role of hydrogen sulfide as an endogenous neuromodulator","volume":"16","author":"Abe","year":"1996","journal-title":"J. Neurosci"},{"key":"10.1074\/jbc.M117.784678_bib2","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1042\/BSR20100003","article-title":"Hydrogen sulfide attenuates cardiac dysfunction in a rat model of heart failure: a mechanism through cardiac mitochondrial protection","volume":"31","author":"Wang","year":"2011","journal-title":"Biosci. Rep"},{"key":"10.1074\/jbc.M117.784678_bib3","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.pharmthera.2009.05.005","article-title":"Actions and interactions of nitric oxide, carbon monoxide and hydrogen sulphide in the cardiovascular system and in inflammation: a tale of three gases!","volume":"123","author":"Li","year":"2009","journal-title":"Pharmacol. Ther"},{"key":"10.1074\/jbc.M117.784678_bib4","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1096\/fj.04-3583fje","article-title":"Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse","volume":"19","author":"Li","year":"2005","journal-title":"FASEB J"},{"key":"10.1074\/jbc.M117.784678_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1586\/ecp.10.134","article-title":"Hydrogen sulfide and inflammation: the good, the bad, the ugly and the promising","volume":"4","author":"Whiteman","year":"2011","journal-title":"Expert Rev. Clin. Pharmacol"},{"key":"10.1074\/jbc.M117.784678_bib6","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1111\/bph.12369","article-title":"Regulation of mitochondrial bioenergetic function by hydrogen sulfide: part I. biochemical and physiological mechanisms","volume":"171","author":"Szabo","year":"2014","journal-title":"Br. J. Pharmacol"},{"key":"10.1074\/jbc.M117.784678_bib7","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1089\/ars.2005.7.795","article-title":"Physiological roles of hydrogen sulfide: synaptic modulation, neuroprotection, and smooth muscle relaxation","volume":"7","author":"Kimura","year":"2005","journal-title":"Antioxid. Redox Signal"},{"key":"10.1074\/jbc.M117.784678_bib8","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1126\/science.1162667","article-title":"H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine \u03b3-lyase","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"10.1074\/jbc.M117.784678_bib9","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1089\/ars.2009.2882","article-title":"Novel insights into hydrogen sulfide: mediated cytoprotection","volume":"12","author":"Calvert","year":"2010","journal-title":"Antioxid. Redox Signal"},{"key":"10.1074\/jbc.M117.784678_bib10","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1161\/CIRCRESAHA.109.199919","article-title":"Hydrogen sulfide mediates cardioprotection through Nrf2 signaling","volume":"105","author":"Calvert","year":"2009","journal-title":"Circ. Res"},{"key":"10.1074\/jbc.M117.784678_bib11","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1161\/CIRCULATIONAHA.112.000855","article-title":"H2S protects against pressure overload-induced heart failure via upregulation of endothelial nitric oxide synthase","volume":"127","author":"Kondo","year":"2013","journal-title":"Circulation"},{"key":"10.1074\/jbc.M117.784678_bib12","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1113\/expphysiol.2011.059725","article-title":"Cytoprotective actions of hydrogen sulfide in ischaemia-reperfusion injury","volume":"96","author":"King","year":"2011","journal-title":"Exp. Physiol"},{"key":"10.1074\/jbc.M117.784678_bib13","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/s00395-005-0569-9","article-title":"Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury: evidence for a role of K ATP channels","volume":"101","author":"Johansen","year":"2006","journal-title":"Basic Res. Cardiol"},{"key":"10.1074\/jbc.M117.784678_bib14","article-title":"Hydrogen sulfide protects HUVECs against hydrogen peroxide induced mitochondrial dysfunction and oxidative stress","volume":"8","author":"Wen","year":"2013","journal-title":"PloS One"},{"key":"10.1074\/jbc.M117.784678_bib15","doi-asserted-by":"crossref","first-page":"15560","DOI":"10.1073\/pnas.0705891104","article-title":"Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function","volume":"104","author":"Elrod","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M117.784678_bib16","doi-asserted-by":"crossref","first-page":"6336","DOI":"10.1021\/jacs.6b01373","article-title":"pH-controlled hydrogen sulfide release for myocardial ischemia-reperfusion injury","volume":"138","author":"Kang","year":"2016","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.784678_bib17","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1126\/science.1108581","article-title":"H2S induces a suspended animation-like state in mice","volume":"308","author":"Blackstone","year":"2005","journal-title":"Science"},{"key":"10.1074\/jbc.M117.784678_bib18","doi-asserted-by":"crossref","first-page":"R51","DOI":"10.1186\/cc10016","article-title":"Administration of hydrogen sulfide via extracorporeal membrane lung ventilation in sheep with partial cardiopulmonary bypass perfusion: a proof of concept study on metabolic and vasomotor effects","volume":"15","author":"Derwall","year":"2011","journal-title":"Crit. Care"},{"key":"10.1074\/jbc.M117.784678_bib19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/SHK.0b013e3181e86f49","article-title":"Intravenous hydrogen sulfide does not induce hypothermia or improve survival from hemorrhagic shock in pigs","volume":"35","author":"Drabek","year":"2011","journal-title":"Shock"},{"key":"10.1074\/jbc.M117.784678_bib20","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1089\/ars.2013.5339","article-title":"Enzymology of H2S biogenesis, decay and signaling","volume":"20","author":"Kabil","year":"2014","journal-title":"Antioxid. Redox Signal"},{"key":"10.1074\/jbc.M117.784678_bib21","doi-asserted-by":"crossref","first-page":"30901","DOI":"10.1074\/jbc.M114.602664","article-title":"Organization of the human mitochondrial hydrogen sulfide oxidation pathway","volume":"289","author":"Libiad","year":"2014","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.784678_bib22","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.bbabio.2010.04.004","article-title":"Oxidation of hydrogen sulfide remains a priority in mammalian cells and causes reverse electron transfer in colonocytes","volume":"1797","author":"Lagoutte","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M117.784678_bib23","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/nchembio.1834","article-title":"Biogenesis of reactive sulfur species for signaling by hydrogen sulfide oxidation pathways","volume":"11","author":"Mishanina","year":"2015","journal-title":"Nat. Chem. Biol"},{"key":"10.1074\/jbc.M117.784678_bib24","doi-asserted-by":"crossref","first-page":"3414","DOI":"10.1039\/C5SC04818D","article-title":"Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation","volume":"7","author":"Wedmann","year":"2016","journal-title":"Chem. Sci"},{"key":"10.1074\/jbc.M117.784678_bib25","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1042\/BST20130070","article-title":"Sulfide inhibition of and metabolism by cytochrome c oxidase","volume":"41","author":"Nicholls","year":"2013","journal-title":"Biochem. Soc. Trans"},{"key":"10.1074\/jbc.M117.784678_bib26","doi-asserted-by":"crossref","first-page":"12016","DOI":"10.1021\/ja3009693","article-title":"Chemical characterization of the smallest S-nitrosothiol, HSNO: cellular cross-talk of H2S and S-nitrosothiols","volume":"134","author":"Filipovic","year":"2012","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.784678_bib27","doi-asserted-by":"crossref","first-page":"12061","DOI":"10.1002\/anie.201305669","article-title":"Generation of HNO and HSNO from nitrite by heme-iron-catalyzed metabolism with H2S","volume":"52","author":"Miljkovic","year":"2013","journal-title":"Angew. Chem. Int. Ed. Engl"},{"key":"10.1074\/jbc.M117.784678_bib28","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1089\/ars.2011.4289","article-title":"Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications","volume":"16","author":"Murphy","year":"2012","journal-title":"Antioxid. Redox Signal"},{"key":"10.1074\/jbc.M117.784678_bib29","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/ajmg.a.10847","article-title":"Endogenous hydrogen sulfide overproduction in Down syndrome","volume":"116A","author":"Kamoun","year":"2003","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1074\/jbc.M117.784678_bib30","doi-asserted-by":"crossref","first-page":"11767","DOI":"10.1074\/jbc.M113.524645","article-title":"Decreased cystathionine-\u03b3-lyase (CSE) activity in livers of type 1 diabetic rats and peripheral blood mononuclear cells (PBMC) of type 1 diabetic patients","volume":"289","author":"Manna","year":"2014","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.784678_bib31","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/nm.1907","article-title":"Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy","volume":"15","author":"Tiranti","year":"2009","journal-title":"Nat. Med"},{"key":"10.1074\/jbc.M117.784678_bib32","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1039\/c2cc17658k","article-title":"An ICT-based strategy to a colorimetric and ratiometric fluorescence probe for hydrogen sulfide in living cells","volume":"48","author":"Yu","year":"2012","journal-title":"Chem. Commun. (Camb.)"},{"key":"10.1074\/jbc.M117.784678_bib33","doi-asserted-by":"crossref","first-page":"7131","DOI":"10.1073\/pnas.1302193110","article-title":"Cell-trappable fluorescent probes for endogenous hydrogen sulfide signaling and imaging H2O2-dependent H2S production","volume":"110","author":"Lin","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M117.784678_bib34","doi-asserted-by":"crossref","first-page":"9204","DOI":"10.1021\/ja802883k","article-title":"A photoactivatable push-pull fluorophore for single-molecule imaging in live cells","volume":"130","author":"Lord","year":"2008","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.784678_bib35","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.niox.2014.11.008","article-title":"Fluorescent probes for hydrogen sulfide (H2S) and sulfane sulfur and their applications to biological studies","volume":"46","author":"Shimamoto","year":"2015","journal-title":"Nitric Oxide"},{"key":"10.1074\/jbc.M117.784678_bib36","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.1039\/C4CS00298A","article-title":"Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems","volume":"44","author":"Lin","year":"2015","journal-title":"Chem. Soc. Rev"},{"key":"10.1074\/jbc.M117.784678_bib37","doi-asserted-by":"crossref","first-page":"15330","DOI":"10.1021\/jacs.5b10675","article-title":"Mechanistic insights into the H2S-mediated reduction of aryl azides commonly used in H2S Detection","volume":"137","author":"Henthorn","year":"2015","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.784678_bib38","doi-asserted-by":"crossref","first-page":"9993","DOI":"10.1002\/anie.201604892","article-title":"A single fluorescent probe to visualize hydrogen sulfide and hydrogen polysulfides with different fluorescence signals","volume":"55","author":"Chen","year":"2016","journal-title":"Angew. Chem. Int. Ed. Engl"},{"key":"10.1074\/jbc.M117.784678_bib39","doi-asserted-by":"crossref","first-page":"11480","DOI":"10.1002\/anie.201605757","article-title":"A synthetic supramolecular receptor for the hydrosulfide anion","volume":"55","author":"Hartle","year":"2016","journal-title":"Angew. Chem. Int. Ed. Engl"},{"key":"10.1074\/jbc.M117.784678_bib40","doi-asserted-by":"crossref","first-page":"4843","DOI":"10.1039\/C5DT04563K","article-title":"Spectroscopic investigations into the binding of hydrogen sulfide to synthetic picket-fence porphyrins","volume":"45","author":"Hartle","year":"2016","journal-title":"Dalton Trans"},{"key":"10.1074\/jbc.M117.784678_bib41","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/srep00499","article-title":"Hydrogen sulfide and resolution of acute inflammation: a comparative study utilizing a novel fluorescent probe","volume":"2","author":"Dufton","year":"2012","journal-title":"Sci. Rep"},{"key":"10.1074\/jbc.M117.784678_bib42","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1039\/c2sc20537h","article-title":"A fluorescent probe for rapid detection of hydrogen sulfide in blood plasma and brain tissues in mice","volume":"3","author":"Qian","year":"2012","journal-title":"Chem. Sci"},{"key":"10.1074\/jbc.M117.784678_bib43","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.tips.2012.03.010","article-title":"Mitochondrial pharmacology","volume":"33","author":"Smith","year":"2012","journal-title":"Trends Pharmacol. Sci"},{"key":"10.1074\/jbc.M117.784678_bib44","doi-asserted-by":"crossref","first-page":"5407","DOI":"10.1073\/pnas.0931245100","article-title":"Delivery of bioactive molecules to mitochondria in vivo","volume":"100","author":"Smith","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M117.784678_bib45","doi-asserted-by":"crossref","first-page":"4767","DOI":"10.1039\/c2cc30730h","article-title":"Selective turn-on fluorescent probes for imaging hydrogen sulfide in living cells","volume":"48","author":"Montoya","year":"2012","journal-title":"Chem. Commun. (Camb.)"},{"key":"10.1074\/jbc.M117.784678_bib46","doi-asserted-by":"crossref","first-page":"10078","DOI":"10.1021\/ja203661j","article-title":"Reaction-based fluorescent probes for selective imaging of hydrogen sulfide in living cells","volume":"133","author":"Lippert","year":"2011","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.784678_bib47","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.cmet.2011.02.003","article-title":"Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix","volume":"13","author":"Cochem\u00e9","year":"2011","journal-title":"Cell Metab"},{"key":"10.1074\/jbc.M117.784678_bib48","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1038\/nprot.2012.035","article-title":"Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila","volume":"7","author":"Cochem\u00e9","year":"2012","journal-title":"Nat. Protoc"},{"key":"10.1074\/jbc.M117.784678_bib49","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.bbagen.2013.05.026","article-title":"Using exomarkers to assess mitochondrial reactive species in vivo","volume":"1840","author":"Logan","year":"2014","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M117.784678_bib50","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.freeradbiomed.2013.11.025","article-title":"A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes","volume":"67","author":"Pun","year":"2014","journal-title":"Free Radic. Biol. Med"},{"key":"10.1074\/jbc.M117.784678_bib51","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/oxfordjournals.jbchem.a134614","article-title":"Transport of the precursor for sulfite oxidase into intermembrane space of liver mitochondria: characterization of import and processing activities","volume":"95","author":"Ono","year":"1984","journal-title":"J. Biochem"},{"key":"10.1074\/jbc.M117.784678_bib52","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1002\/cbic.201402312","article-title":"A persulfide analogue of the nitrosothiol SNAP: formation, characterization and reactivity","volume":"15","author":"Artaud","year":"2014","journal-title":"ChemBioChem"},{"key":"10.1074\/jbc.M117.784678_bib53","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1021\/jacs.5b10494","article-title":"Biosynthesis and reactivity of cysteine persulfides in signaling","volume":"138","author":"Yadav","year":"2016","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.784678_bib54","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.febslet.2004.06.045","article-title":"Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant","volume":"571","author":"Asin-Cayuela","year":"2004","journal-title":"FEBS Lett"},{"key":"10.1074\/jbc.M117.784678_bib55","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.redox.2015.04.008","article-title":"Protection against renal ischemia-reperfusion injury in vivo by the mitochondria targeted antioxidant MitoQ","volume":"5","author":"Dare","year":"2015","journal-title":"Redox. Biol"},{"key":"10.1074\/jbc.M117.784678_bib56","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/j.healun.2015.05.007","article-title":"The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model","volume":"34","author":"Dare","year":"2015","journal-title":"J. Heart Lung Transplant"},{"key":"10.1074\/jbc.M117.784678_bib57","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1093\/jnen\/nlw037","article-title":"Decreased coenzyme Q10 levels in multiple system atrophy cerebellum","volume":"75","author":"Barca","year":"2016","journal-title":"J. Neuropathol. Exp. Neurol"},{"key":"10.1074\/jbc.M117.784678_bib58","doi-asserted-by":"crossref","first-page":"20002","DOI":"10.1074\/jbc.M113.466177","article-title":"Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase","volume":"288","author":"Yadav","year":"2013","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.784678_bib59","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.bbagen.2010.06.001","article-title":"Rapid uptake of lipophilic triphenylphosphonium cations by mitochondria in vivo following intravenous injection: implications for mitochondria-specific therapies and probes","volume":"1800","author":"Porteous","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M117.784678_bib60","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1016\/j.bbagen.2013.02.005","article-title":"P-glycoprotein (Mdr1a\/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain","volume":"1830","author":"Porteous","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M117.784678_bib61","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S1387-3806(99)00020-2","article-title":"Charge-remote and charge-proximate fragmentations in deuterium-labeled n-hexyadecyltriphenylphosphonium cations","volume":"188","author":"Denekamp","year":"1999","journal-title":"Int. J. Mass Spectrom"},{"key":"10.1074\/jbc.M117.784678_bib62","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/nature13909","article-title":"Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS","volume":"515","author":"Chouchani","year":"2014","journal-title":"Nature"},{"key":"10.1074\/jbc.M117.784678_bib63","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.cmet.2015.12.009","article-title":"A unifying mechanism for mitochondrial superoxide production during ischemia-reperfusion injury","volume":"23","author":"Chouchani","year":"2016","journal-title":"Cell Metab"},{"key":"10.1074\/jbc.M117.784678_bib64","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1073\/pnas.87.4.1620","article-title":"Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide","volume":"87","author":"Beckman","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M117.784678_bib65","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1039\/j19680000450","article-title":"The chemistry of pernitrites: part 1. kinetics of decomposition of pernitrous acid","volume":"1968","author":"Hughes","year":"1968","journal-title":"J. Am. Chem. Soc. A"},{"key":"10.1074\/jbc.M117.784678_bib66","doi-asserted-by":"crossref","first-page":"454","DOI":"10.4319\/lo.1969.14.3.0454","article-title":"Spectrophotometric determination of hydrogen sulfide in natural waters","volume":"14","author":"Cline","year":"1969","journal-title":"Limnology Oceanography"},{"key":"10.1074\/jbc.M117.784678_bib67","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S0021-9258(18)57021-6","article-title":"Determination of serum protein by means of the biuret reaction","volume":"177","author":"Gornall","year":"1949","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.784678_bib68","first-page":"733","article-title":"Heart transplantation in congenic strains of mice","volume":"5","author":"Corry","year":"1973","journal-title":"Transplant. Proc"},{"key":"10.1074\/jbc.M117.784678_bib69","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1161\/CIRCEP.110.954149","article-title":"Feasibility of circumferential pulmonary vein isolation using a novel endoscopic ablation system","volume":"3","author":"Schmidt","year":"2010","journal-title":"Circ. Arrhythm. Electrophysiol"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820418769?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820418769?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M117.784678","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T13:24:00Z","timestamp":1619875440000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820418769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":69,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0021925820418769"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m117.784678","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Assessment of H2S in vivo using the newly developed mitochondria-targeted mass spectrometry probe MitoA","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M117.784678","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}