{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T11:13:46Z","timestamp":1772882026650,"version":"3.50.1"},"reference-count":78,"publisher":"Elsevier BV","issue":"46","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T00:00:00Z","timestamp":1599436800000},"content-version":"vor","delay-in-days":1041,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 GM037539"],"award-info":[{"award-number":["R01 GM037539"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01 CA207824"],"award-info":[{"award-number":["U01 CA207824"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P41 GM103390"],"award-info":[{"award-number":["P41 GM103390"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P41 RR018502"],"award-info":[{"award-number":["P41 RR018502"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1074\/jbc.m117.809160","type":"journal-article","created":{"date-parts":[[2017,9,20]],"date-time":"2017-09-20T00:40:10Z","timestamp":1505868010000},"page":"18897-18915","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["O2 sensing\u2013associated glycosylation exposes the F-box\u2013combining site of the Dictyostelium Skp1 subunit in E3 ubiquitin ligases"],"prefix":"10.1016","volume":"292","author":[{"given":"M. Osman","family":"Sheikh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Thieker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Chalmers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"Schafer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayumi","family":"Ishihara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Parastoo","family":"Azadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Woods","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John N.","family":"Glushka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad","family":"Bendiak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James H.","family":"Prestegard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher M.","family":"West","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M117.809160_bib1","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.bbamcr.2004.09.027","article-title":"A hitchhiker\u2019s guide to the cullin ubiquitin ligases: SCF and its kin","volume":"1695","author":"Willems","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M117.809160_bib2","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1146\/annurev.biochem.78.101807.093809","article-title":"RING domain E3 ubiquitin ligases","volume":"78","author":"Deshaies","year":"2009","journal-title":"Annu. Rev. Biochem"},{"key":"10.1074\/jbc.M117.809160_bib3","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/nrm3582","article-title":"Mechanisms and function of substrate recruitment by F-box proteins","volume":"14","author":"Skaar","year":"2013","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"10.1074\/jbc.M117.809160_bib4","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.cell.2013.02.024","article-title":"Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins","volume":"153","author":"Pierce","year":"2013","journal-title":"Cell"},{"key":"10.1074\/jbc.M117.809160_bib5","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.12102","article-title":"Structural and kinetic analysis of the COP9-signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle","volume":"5","author":"Mosadeghi","year":"2016","journal-title":"Elife"},{"key":"10.1074\/jbc.M117.809160_bib6","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.bbagen.2009.11.006","article-title":"A cytoplasmic prolyl hydroxylation and glycosylation pathway modifies Skp1 and regulates O2-dependent development in Dictyostelium","volume":"1800","author":"West","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M117.809160_bib7","doi-asserted-by":"crossref","first-page":"25098","DOI":"10.1074\/jbc.M112.355446","article-title":"The Skp1 protein from Toxoplasma is modified by a cytoplasmic prolyl 4-hydroxylase associated with oxygen sensing in the social amoeba Dictyostelium","volume":"287","author":"Xu","year":"2012","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib8","doi-asserted-by":"crossref","first-page":"3349","DOI":"10.1242\/dev.000893","article-title":"Prolyl 4-hydroxylase-1 mediates O2 signaling during development of Dictyostelium","volume":"134","author":"West","year":"2007","journal-title":"Development"},{"key":"10.1074\/jbc.M117.809160_bib9","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1074\/jbc.M111.314021","article-title":"Skp1 prolyl 4-hydroxylase of Dictyostelium mediates glycosylation-independent and -dependent responses to O2 without affecting Skp1 stability","volume":"287","author":"Zhang","year":"2012","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib10","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.mib.2015.04.006","article-title":"Oxygen sensing by protozoans: how they catch their breath","volume":"26","author":"West","year":"2015","journal-title":"Curr. Opin. Microbiol"},{"key":"10.1074\/jbc.M117.809160_bib11","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1074\/mcp.M114.044560","article-title":"Glycosylation of Skp1 promotes formation of SCF complexes in Dictyostelium","volume":"14","author":"Sheikh","year":"2015","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1074\/jbc.M117.809160_bib12","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1021\/bi401707y","article-title":"Glycosylation of Skp1 affects its conformation and promotes binding to a model F-Box protein","volume":"53","author":"Sheikh","year":"2014","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M117.809160_bib13","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.cell.2012.05.036","article-title":"Systematic functional prioritization of protein posttranslational modifications","volume":"150","author":"Beltrao","year":"2012","journal-title":"Cell"},{"key":"10.1074\/jbc.M117.809160_bib14","doi-asserted-by":"crossref","first-page":"32766","DOI":"10.1074\/jbc.M113.511303","article-title":"Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex","volume":"288","author":"Yumimoto","year":"2013","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib15","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.molcel.2012.08.015","article-title":"Signal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48\/p97","volume":"48","author":"Yen","year":"2012","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M117.809160_bib16","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s12104-016-9699-2","article-title":"Backbone and side chain assignments of human cell cycle regulatory protein S-phase kinase-associated protein 1","volume":"10","author":"Kachariya","year":"2016","journal-title":"Biomol. NMR Assign"},{"key":"10.1074\/jbc.M117.809160_bib17","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/prot.24963","article-title":"Molecular dynamics simulations elucidate the mode of protein recognition by Skp1 and the F-box domain in the SCF complex","volume":"84","author":"Chandra Dantu","year":"2016","journal-title":"Proteins"},{"key":"10.1074\/jbc.M117.809160_bib18","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/35042620","article-title":"Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex","volume":"408","author":"Schulman","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M117.809160_bib19","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.sbi.2010.08.010","article-title":"Structural assembly of cullin-RING ubiquitin ligase complexes","volume":"20","author":"Zimmerman","year":"2010","journal-title":"Curr. Opin. Struct. Biol"},{"key":"10.1074\/jbc.M117.809160_bib20","series-title":"Introduction to Glycobiology","year":"2011"},{"key":"10.1074\/jbc.M117.809160_bib21","doi-asserted-by":"crossref","first-page":"9076","DOI":"10.1074\/jbc.M113.528679","article-title":"Novel regulation of Skp1 by the Dictyostelium AgtA \u03b1-galactosyltransferase involves the Skp1-binding activity of its WD40 repeat domain","volume":"289","author":"Schafer","year":"2014","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib22","doi-asserted-by":"crossref","first-page":"28896","DOI":"10.1074\/jbc.M109.022574","article-title":"Role of a cytoplasmic dual-function glycosyltransferase in O2-regulation of development in Dictyostelium","volume":"284","author":"Wang","year":"2009","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib23","doi-asserted-by":"crossref","first-page":"29050","DOI":"10.1074\/jbc.M313858200","article-title":"Specificity of a soluble UDP-galactose: fucoside \u03b11,3-galactosyltransferase that modifies the cytoplasmic glycoprotein Skp1 in Dictyostelium","volume":"279","author":"Ketcham","year":"2004","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib24","doi-asserted-by":"crossref","first-page":"18242","DOI":"10.1074\/jbc.273.29.18242","article-title":"The cytoplasmic F-box binding protein SKP1 contains a novel pentasaccharide linked to hydroxyproline in Dictyostelium","volume":"273","author":"Teng-umnuay","year":"1998","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib25","doi-asserted-by":"crossref","first-page":"12024","DOI":"10.1074\/jbc.271.20.12024","article-title":"Purification and characterization of an \u03b11,2-l-fucosyltransferase, which modifies the cytosolic protein FP21, from the cytosol of Dictyostelium","volume":"271","author":"West","year":"1996","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib26","doi-asserted-by":"crossref","first-page":"12713","DOI":"10.1074\/jbc.M513664200","article-title":"Molecular characterization of a novel UDP-galactose:fucoside \u03b13-galactosyltransferase that modifies Skp1 in the cytoplasm of Dictyostelium","volume":"281","author":"Ercan","year":"2006","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib27","doi-asserted-by":"crossref","first-page":"11779","DOI":"10.1002\/chem.201501598","article-title":"Chemical synthesis of a glycopeptide derived from Skp1 for probing protein specific glycosylation","volume":"21","author":"Chinoy","year":"2015","journal-title":"Chemistry"},{"key":"10.1074\/jbc.M117.809160_bib28","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.carres.2013.06.026","article-title":"Complete 1H and 13C NMR chemical shift assignments of mono- to tetrasaccharides as basis for NMR chemical shift predictions of oligosaccharides using the computer program CASPER","volume":"380","author":"R\u00f6nnols","year":"2013","journal-title":"Carbohydr. Res"},{"key":"10.1074\/jbc.M117.809160_bib29","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1016\/j.carres.2006.02.034","article-title":"Sequence determination of oligosaccharides and regular polysaccharides using NMR spectroscopy and a novel Web-based version of the computer program CASPER","volume":"341","author":"Jansson","year":"2006","journal-title":"Carbohydr. Res"},{"key":"10.1074\/jbc.M117.809160_bib30","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1021\/ac1032534","article-title":"Structure analysis of glycans by NMR chemical shift prediction","volume":"83","author":"Lundborg","year":"2011","journal-title":"Anal. Chem"},{"key":"10.1074\/jbc.M117.809160_bib31","series-title":"AMBER 12","year":"2012"},{"key":"10.1074\/jbc.M117.809160_bib32","series-title":"GLYCAM Web, Complex Carbohydrate Research Center","year":"2014"},{"key":"10.1074\/jbc.M117.809160_bib33","doi-asserted-by":"crossref","first-page":"5853","DOI":"10.1021\/bi0354886","article-title":"Oligosaccharides implicated in recognition are predicted to have relatively ordered structures","volume":"43","author":"Almond","year":"2004","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M117.809160_bib34","doi-asserted-by":"crossref","first-page":"4674","DOI":"10.1021\/bi992050q","article-title":"Conformational studies of human milk oligosaccharides using 1H-13C one-bond NMR residual dipolar couplings","volume":"39","author":"Martin-Pastor","year":"2000","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M117.809160_bib35","series-title":"NMR for Physical and Biological Scientists","first-page":"95","year":"2007"},{"key":"10.1074\/jbc.M117.809160_bib36","series-title":"Protein NMR Spectroscopy","first-page":"337","author":"Cavanagh","year":"2007"},{"key":"10.1074\/jbc.M117.809160_bib37","doi-asserted-by":"crossref","first-page":"4546","DOI":"10.1021\/ja00381a009","article-title":"Model-free approach to the interpretation of nuclear magnetic-resonance relaxation in macromolecules. 1. Theory and range of validity","volume":"104","author":"Lipari","year":"1982","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.809160_bib38","doi-asserted-by":"crossref","first-page":"4559","DOI":"10.1021\/ja00381a010","article-title":"Model-free approach to the interpretation of nuclear magnetic-resonance relaxation in macromolecules. 2. Analysis of experimental results","volume":"104","author":"Lipari","year":"1982","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.809160_bib39","series-title":"Encyclopedia of Chemical Physics and Physical Chemistry","year":"2001"},{"key":"10.1074\/jbc.M117.809160_bib40","doi-asserted-by":"crossref","first-page":"13464","DOI":"10.1021\/ja4054702","article-title":"Stabilization of branched oligosaccharides: Lewis(x) benefits from a nonconventional C-H.O hydrogen bond","volume":"135","author":"Zierke","year":"2013","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.809160_bib41","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/S0006-3495(80)85027-2","article-title":"Molecular dynamics of sugars bound to wheat germ agglutinin, as studied by deuterium nuclear magnetic resonance","volume":"32","author":"Neurohr","year":"1980","journal-title":"Biophys. J"},{"key":"10.1074\/jbc.M117.809160_bib42","doi-asserted-by":"crossref","first-page":"4268","DOI":"10.1074\/jbc.M115.703751","article-title":"The E3 ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development","volume":"291","author":"Rahman","year":"2016","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib43","doi-asserted-by":"crossref","first-page":"11570","DOI":"10.1021\/jp304116d","article-title":"Exploring the molecular mechanism of stabilization of the adhesion domains of human CD2 by N-glycosylation","volume":"116","author":"Wang","year":"2012","journal-title":"J. Phys. Chem. B"},{"key":"10.1074\/jbc.M117.809160_bib44","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1021\/bi962723u","article-title":"Kinetic and thermodynamic thermal stabilities of ribonuclease A and ribonuclease B","volume":"36","author":"Arnold","year":"1997","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M117.809160_bib45","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M117.800102","article-title":"O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking","author":"Takeuchi","year":"2017","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib46","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1021\/bi501380t","article-title":"Intramolecular N-glycan\/polypeptide interactions observed at multiple N-glycan remodeling steps through (13C,15N)-N-acetylglucosamine labeling of immunoglobulin G1","volume":"54","author":"Barb","year":"2015","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M117.809160_bib47","doi-asserted-by":"crossref","first-page":"14127","DOI":"10.1073\/pnas.1105880108","article-title":"Glycosylation of the enhanced aromatic sequon is similarly stabilizing in three distinct reverse turn contexts","volume":"108","author":"Price","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1074\/jbc.M117.809160_bib48","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1472-6807-12-7","article-title":"Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking subsite C6","volume":"12","author":"Venkatramani","year":"2012","journal-title":"BMC Struct. Biol"},{"key":"10.1074\/jbc.M117.809160_bib49","doi-asserted-by":"crossref","first-page":"46527","DOI":"10.1074\/jbc.M208824200","article-title":"A bifunctional diglycosyltransferase forms the Fuc\u03b11,2Gal\u03b21,3-disaccharide on Skp1 in the cytoplasm of Dictyostelium","volume":"277","author":"Van Der Wel","year":"2002","journal-title":"J. Biol. Chem"},{"key":"10.1074\/jbc.M117.809160_bib50","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1021\/bi101977w","article-title":"Requirements for Skp1 processing by cytosolic prolyl 4(trans)-hydroxylase and \u03b1-N-acetylglucosaminyltransferase enzymes involved in O2 signaling in Dictyostelium","volume":"50","author":"van der Wel","year":"2011","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M117.809160_bib51","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0003-2697(92)90048-C","article-title":"A comprehensive procedure for preparation of partially methylated alditol acetates from glycoprotein carbohydrates","volume":"203","author":"Anumula","year":"1992","journal-title":"Anal. Biochem"},{"key":"10.1074\/jbc.M117.809160_bib52","first-page":"422","article-title":"Gradient-enhanced spectroscopy","volume":"87","author":"Hurd","year":"1990","journal-title":"J. Magn. Reson"},{"key":"10.1074\/jbc.M117.809160_bib53","first-page":"335","article-title":"An improved sequence for broad-band decoupling\u2014WALTZ-16","volume":"52","author":"Shaka","year":"1983","journal-title":"J. Magn. Reson"},{"key":"10.1074\/jbc.M117.809160_bib54","first-page":"274","article-title":"Iterative schemes for bilinear operators: application to spin decoupling","volume":"77","author":"Shaka","year":"1988","journal-title":"J. Magn. Reson"},{"key":"10.1074\/jbc.M117.809160_bib55","doi-asserted-by":"crossref","first-page":"3938","DOI":"10.1002\/anie.200351947","article-title":"Elimination of zero-quantum interference in two-dimensional NMR spectra","volume":"42","author":"Thrippleton","year":"2003","journal-title":"Angew. Chem. Int. Ed. Engl"},{"key":"10.1074\/jbc.M117.809160_bib56","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1021\/ja00268a061","article-title":"Proton and carbon-13 assignments from sensitivity-enhanced detection of heteronuclear multiple-bond connectivity by 2D multiple quantum NMR","volume":"108","author":"Bax","year":"1986","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.809160_bib57","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/BF00197809","article-title":"NMRPipe: a multidimensional spectral processing system based on UNIX pipes","volume":"6","author":"Delaglio","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"10.1074\/jbc.M117.809160_bib58","series-title":"SPARKY 3","year":"2008"},{"key":"10.1074\/jbc.M117.809160_bib59","first-page":"313","article-title":"Using NMRView to visualize and analyze the NMR spectra of macromolecules","volume":"278","author":"Johnson","year":"2004","journal-title":"Methods Mol. Biol"},{"key":"10.1074\/jbc.M117.809160_bib60","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1021\/ja00012a001","article-title":"Intramolecular motions of a zinc finger DNA-binding domain from Xfin characterized by proton-detected natural abundance 13C heteronuclear NMR spectroscopy","volume":"113","author":"Palmer","year":"1991","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.809160_bib61","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1006\/jmbi.1994.0073","article-title":"Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme","volume":"246","author":"Mandel","year":"1995","journal-title":"J. Mol. Biol"},{"key":"10.1074\/jbc.M117.809160_bib62","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1021\/ct200909j","article-title":"Routine microsecond molecular dynamics simulations with AMBER on GPUs. 1. Generalized Born","volume":"8","author":"G\u00f6tz","year":"2012","journal-title":"J. Chem. Theory Comput"},{"key":"10.1074\/jbc.M117.809160_bib63","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1002\/jcc.20290","article-title":"The Amber biomolecular simulation programs","volume":"26","author":"Case","year":"2005","journal-title":"J. Comput. Chem"},{"key":"10.1074\/jbc.M117.809160_bib64","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1002\/jcc.20820","article-title":"GLYCAM06: a generalizable biomolecular force field: carbohydrates","volume":"29","author":"Kirschner","year":"2008","journal-title":"J. Comput. Chem"},{"key":"10.1074\/jbc.M117.809160_bib65","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1063\/1.445869","article-title":"Comparison of simple potential functions for simulating liquid water","volume":"79","author":"Jorgensen","year":"1983","journal-title":"J. Chem. Phys"},{"key":"10.1074\/jbc.M117.809160_bib66","doi-asserted-by":"crossref","first-page":"10089","DOI":"10.1063\/1.464397","article-title":"Particle mesh Ewald: an N log (N) method for Ewald sums in large systems","volume":"98","author":"Darden","year":"1993","journal-title":"J. Chem. Physics"},{"key":"10.1074\/jbc.M117.809160_bib67","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1002\/jcc.20301","article-title":"A new set of molecular mechanics parameters for hydroxyproline and its use in molecular dynamics simulations of collagen-like peptides","volume":"26","author":"Park","year":"2005","journal-title":"J. Comput. Chem"},{"key":"10.1074\/jbc.M117.809160_bib68","doi-asserted-by":"crossref","first-page":"11670","DOI":"10.1021\/ja073488d","article-title":"Effects of glycosylation of (2S,4R)-4-hydroxyproline on the conformation, kinetics, and thermodynamics of prolyl amide isomerization","volume":"129","author":"Owens","year":"2007","journal-title":"J. Am. Chem. Soc"},{"key":"10.1074\/jbc.M117.809160_bib69","first-page":"89","article-title":"UniProtKB\/Swiss-Prot","volume":"406","author":"Boutet","year":"2007","journal-title":"Methods Mol. Biol"},{"key":"10.1074\/jbc.M117.809160_bib70","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1093\/bioinformatics\/bti770","article-title":"The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling","volume":"22","author":"Arnold","year":"2006","journal-title":"Bioinformatics"},{"key":"10.1074\/jbc.M117.809160_bib71","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/jcc.20084","article-title":"UCSF Chimera\u2013a visualization system for exploratory research and analysis","volume":"25","author":"Pettersen","year":"2004","journal-title":"J. Comput. Chem"},{"key":"10.1074\/jbc.M117.809160_bib72","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.1021\/ct400341p","article-title":"PTRAJ and CPPTRAJ: software for processing and analysis of molecular dynamics trajectory data","volume":"9","author":"Roe","year":"2013","journal-title":"J. Chem. Theory Comput"},{"key":"10.1074\/jbc.M117.809160_bib73","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0263-7855(96)00018-5","article-title":"VMD: visual molecular dynamics","volume":"14","author":"Humphrey","year":"1996","journal-title":"J. Mol. Graphics"},{"key":"10.1074\/jbc.M117.809160_bib74","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1093\/glycob\/cwv091","article-title":"Symbol nomenclature for graphical representations of glycans","volume":"25","author":"Varki","year":"2015","journal-title":"Glycobiology"},{"key":"10.1074\/jbc.M117.809160_bib75","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1093\/glycob\/cww076","article-title":"3D implementation of the symbol nomenclature for graphical representation of glycans","volume":"26","author":"Thieker","year":"2016","journal-title":"Glycobiology"},{"key":"10.1074\/jbc.M117.809160_bib76","series-title":"Spin Dynamics: Basics of Nuclear Magnetic Resonance","first-page":"543","year":"2008"},{"key":"10.1074\/jbc.M117.809160_bib77","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jmr.2016.01.006","article-title":"Direct NOE simulation from long MD trajectories","volume":"265","author":"Chalmers","year":"2016","journal-title":"J. Magn. Reson"},{"key":"10.1074\/jbc.M117.809160_bib78","doi-asserted-by":"crossref","first-page":"7006","DOI":"10.1021\/acs.analchem.5b01413","article-title":"Improved carbohydrate structure generalization scheme for 1H and 13C NMR simulations","volume":"87","author":"Kapaev","year":"2015","journal-title":"Anal. Chem"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820329367?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820329367?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M117.809160","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,4]],"date-time":"2022-01-04T05:20:50Z","timestamp":1641273650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820329367"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":78,"journal-issue":{"issue":"46","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S0021925820329367"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m117.809160","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"O2 sensing\u2013associated glycosylation exposes the F-box\u2013combining site of the Dictyostelium Skp1 subunit in E3 ubiquitin ligases","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M117.809160","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}