{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:19:53Z","timestamp":1791253193116,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"27","license":[{"start":{"date-parts":[[2002,7,1]],"date-time":"2002-07-01T00:00:00Z","timestamp":1025481600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"vor","delay-in-days":6689,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2002,7]]},"DOI":"10.1074\/jbc.m201961200","type":"journal-article","created":{"date-parts":[[2002,7,28]],"date-time":"2002-07-28T22:26:46Z","timestamp":1027895206000},"page":"24717-24727","source":"Crossref","is-referenced-by-count":181,"title":["Increase in Cytosolic Ca2+ Levels through the Activation of Non-selective Cation Channels Induced by Oxidative Stress Causes Mitochondrial Depolarization Leading to Apoptosis-like Death in Leishmania donovaniPromastigotes"],"prefix":"10.1016","volume":"277","author":[{"given":"Sikha Bettina","family":"Mukherjee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manika","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganapasam","family":"Sudhandiran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandrima","family":"Shaha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M201961200_bib1","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.281.5381.1309","volume":"258","author":"Green","year":"1998","journal-title":"Science"},{"key":"10.1074\/jbc.M201961200_bib2","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000046884","volume":"10","author":"Gottlieb","year":"2001","journal-title":"Biol. Signals Recept."},{"key":"10.1074\/jbc.M201961200_bib3","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1006\/excr.1994.1264","volume":"214","author":"Cossarizza","year":"1994","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M201961200_bib4","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0014-5793(96)00280-3","volume":"384","author":"Zamzami","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M201961200_bib5","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1084\/jem.181.5.1661","volume":"181","author":"Zamzami","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1074\/jbc.M201961200_bib6","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1006\/excr.2000.4901","volume":"257","author":"Li","year":"2000","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M201961200_bib7","doi-asserted-by":"crossref","first-page":"3544","DOI":"10.1182\/blood.V97.11.3544","volume":"11","author":"Dvorakova","year":"2001","journal-title":"Blood"},{"key":"10.1074\/jbc.M201961200_bib8","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/(SICI)1097-4547(19971101)50:3<413::AID-JNR7>3.0.CO;2-L","volume":"50","author":"Satoh","year":"1997","journal-title":"J. Neurosci. Res."},{"key":"10.1074\/jbc.M201961200_bib9","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0039-6060(99)70148-0","volume":"2","author":"Ehlers","year":"1999","journal-title":"Surgery"},{"key":"10.1074\/jbc.M201961200_bib10","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1523\/JNEUROSCI.20-06-02094.2000","volume":"20","author":"Chinopoulos","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M201961200_bib11","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1749-6632.1999.tb07834.x","volume":"893","author":"Chinopoulos","year":"1999","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1074\/jbc.M201961200_bib12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1023\/A:1005419617371","volume":"31","author":"Lemasters","year":"1999","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1074\/jbc.M201961200_bib13","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1006\/excr.1998.4303","volume":"246","author":"Anderson","year":"1999","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M201961200_bib14","doi-asserted-by":"crossref","first-page":"19150","DOI":"10.1074\/jbc.M100730200","volume":"276","author":"Tagliarino","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib15","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1046\/j.1471-4159.1999.0720529.x","volume":"72","author":"Kruman","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1074\/jbc.M201961200_bib16","doi-asserted-by":"crossref","first-page":"15343","DOI":"10.1074\/jbc.275.20.15343","volume":"275","author":"Koya","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib17","doi-asserted-by":"crossref","first-page":"7208","DOI":"10.1523\/JNEUROSCI.20-19-07208.2000","volume":"20","author":"Ward","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M201961200_bib18","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1006\/bbrc.2001.4371","volume":"281","author":"Kim","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M201961200_bib19","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0014-5793(00)01526-X","volume":"473","author":"Kowaltowski","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M201961200_bib20","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1042\/bj2840463","volume":"284","author":"Vercesi","year":"1992","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M201961200_bib21","first-page":"267","volume":"14 (suppl.)","author":"Chang","year":"1983","journal-title":"Int. Rev. Cytol."},{"key":"10.1074\/jbc.M201961200_bib22","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0166-6851(84)90028-8","volume":"10","author":"Nabi","year":"1984","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1074\/jbc.M201961200_bib23","doi-asserted-by":"crossref","first-page":"2406","DOI":"10.1128\/AAC.44.9.2406-2410.2000","volume":"44","author":"Rais","year":"2000","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1074\/jbc.M201961200_bib24","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s004360050361","volume":"84","author":"Basselin","year":"1998","journal-title":"Parasitol. Res."},{"key":"10.1074\/jbc.M201961200_bib25","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1242\/jcs.114.13.2461","volume":"114","author":"Das","year":"2001","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M201961200_bib26","doi-asserted-by":"crossref","first-page":"7087","DOI":"10.1074\/jbc.275.10.7087","volume":"275","author":"Dey","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib27","doi-asserted-by":"crossref","first-page":"21953","DOI":"10.1074\/jbc.274.31.21953","volume":"274","author":"Bortner","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib28","doi-asserted-by":"crossref","first-page":"5384","DOI":"10.1074\/jbc.M007915200","volume":"276","author":"Eric","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib29","doi-asserted-by":"crossref","first-page":"30580","DOI":"10.1074\/jbc.274.43.30580","volume":"274","author":"Thomas","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib30","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1006\/abio.2000.4498","volume":"280","author":"Senft","year":"2000","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M201961200_bib31","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/0003-2697(88)90354-5","volume":"175","author":"Kricka","year":"1988","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M201961200_bib32","doi-asserted-by":"crossref","first-page":"11619","DOI":"10.1074\/jbc.273.19.11619","volume":"273","author":"Duranteau","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib33","doi-asserted-by":"crossref","first-page":"38680","DOI":"10.1074\/jbc.M005667200","volume":"275","author":"Gonz\u00e1lez","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib34","doi-asserted-by":"crossref","first-page":"32436","DOI":"10.1074\/jbc.272.51.32436","volume":"272","author":"Bortner","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib35","doi-asserted-by":"crossref","first-page":"29067","DOI":"10.1074\/jbc.271.46.29067","volume":"271","author":"Zhang","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib36","doi-asserted-by":"crossref","first-page":"20596","DOI":"10.1074\/jbc.273.32.20596","volume":"273","author":"Savel'ev","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib37","doi-asserted-by":"crossref","first-page":"3671","DOI":"10.1073\/pnas.88.9.3671","volume":"88","author":"Smiley","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M201961200_bib38","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1469-7793.1998.413bq.x","volume":"508","author":"Simpson","year":"1998","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.M201961200_bib39","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1146\/annurev.mi.46.100192.003403","volume":"46","author":"Fairlamb","year":"1992","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1074\/jbc.M201961200_bib40","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/sj.cdd.4400452","volume":"1","author":"Bojes","year":"1999","journal-title":"Cell Death Differ."},{"key":"10.1074\/jbc.M201961200_bib41","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1006\/taap.2001.9159","volume":"173","author":"Panaretakis","year":"2001","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1074\/jbc.M201961200_bib42","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0753-3322(99)80001-8","volume":"52","author":"Nicole","year":"1998","journal-title":"Biomed. Pharmacother."},{"key":"10.1074\/jbc.M201961200_bib43","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1574-6968.1999.tb13495.x","volume":"173","author":"Weldrick","year":"1999","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1074\/jbc.M201961200_bib44","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0014-5793(00)01464-2","volume":"472","author":"Oka","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M201961200_bib45","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/s002320010034","volume":"179","author":"Pariente","year":"2001","journal-title":"J. Membr. Biol."},{"key":"10.1074\/jbc.M201961200_bib46","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1046\/j.1471-4159.2001.00395.x","volume":"78","author":"Geller","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1074\/jbc.M201961200_bib47","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1006\/abbi.1999.1574","volume":"374","author":"Yang","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M201961200_bib48","doi-asserted-by":"crossref","first-page":"25262","DOI":"10.1074\/jbc.M103689200","volume":"276","author":"Ostrander","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib49","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0005-2728(98)00112-1","volume":"1366","author":"Lemasters","year":"1998","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M201961200_bib50","doi-asserted-by":"crossref","first-page":"27510","DOI":"10.1074\/jbc.270.46.27510","volume":"270","author":"Sparagna","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M201961200_bib51","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1080\/10715760000301431","volume":"33","author":"Kim","year":"2000","journal-title":"Free Radic. Res."},{"key":"10.1074\/jbc.M201961200_bib52","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/ki.1996.57","volume":"49","author":"Meyer","year":"1996","journal-title":"Kidney Int."},{"key":"10.1074\/jbc.M201961200_bib53","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1042\/bj3430311","volume":"343","author":"Huser","year":"1999","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M201961200_bib54","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1242\/jcs.112.7.1077","volume":"112","author":"Diaz","year":"1999","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M201961200_bib55","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1242\/jcs.109.5.971","volume":"109","author":"Overly","year":"1996","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M201961200_bib56","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0891-5849(01)00591-3","volume":"31","author":"Anuradha","year":"2001","journal-title":"Free Radic. Biol. Med."},{"key":"10.1074\/jbc.M201961200_bib57","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1006\/abbi.2000.2194","volume":"386","author":"Sultan","year":"2001","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M201961200_bib58","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0166-6851(01)00285-7","volume":"115","author":"Ariyanayagam","year":"2001","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1074\/jbc.M201961200_bib59","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1469-7793.2000.00057.x","volume":"529","author":"Duchen","year":"2000","journal-title":"J. Physiol. (Lond.)"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192581966655X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192581966655X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M201961200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T08:19:30Z","timestamp":1641197970000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002192581966655X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,7]]},"references-count":59,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2002,7]]}},"alternative-id":["S002192581966655X"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m201961200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2002,7]]}}}