{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:20:12Z","timestamp":1789543212833,"version":"build-2803163510"},"reference-count":60,"publisher":"Elsevier BV","issue":"32","license":[{"start":{"date-parts":[[2002,8,1]],"date-time":"2002-08-01T00:00:00Z","timestamp":1028160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T00:00:00Z","timestamp":1603411200000},"content-version":"vor","delay-in-days":6658,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2002,8]]},"DOI":"10.1074\/jbc.m202592200","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T17:58:01Z","timestamp":1032371881000},"page":"28725-28732","source":"Crossref","is-referenced-by-count":115,"title":["Neurosteroids Enhance Spontaneous Glutamate Release in Hippocampal Neurons"],"prefix":"10.1016","volume":"277","author":[{"given":"Douglas A.","family":"Meyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Carta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. Donald","family":"Partridge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas F.","family":"Covey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Fernando","family":"Valenzuela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M202592200_bib1","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/S0306-4530(98)00071-7","volume":"23","author":"Baulieu","year":"1998","journal-title":"Psychoneuroendocrinology"},{"key":"10.1074\/jbc.M202592200_bib2","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0378-4347(99)00563-0","volume":"739","author":"Liere","year":"2000","journal-title":"J. Chromatogr. B Biomed. Sci. Appl."},{"key":"10.1074\/jbc.M202592200_bib3","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1073\/pnas.89.5.1567","volume":"89","author":"Flood","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib4","doi-asserted-by":"crossref","first-page":"10806","DOI":"10.1073\/pnas.92.23.10806","volume":"92","author":"Flood","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib5","doi-asserted-by":"crossref","first-page":"14865","DOI":"10.1073\/pnas.94.26.14865","volume":"94","author":"Vallee","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib6","doi-asserted-by":"crossref","first-page":"14033","DOI":"10.1073\/pnas.241503698","volume":"98","author":"Akwa","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib7","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1046\/j.0953-816x.2001.01817.x","volume":"14","author":"Vallee","year":"2001","journal-title":"Eur. J. Neurosci."},{"key":"10.1074\/jbc.M202592200_bib8","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0306-4522(97)00405-3","volume":"83","author":"Maurice","year":"1998","journal-title":"Neuroscience"},{"key":"10.1074\/jbc.M202592200_bib9","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/S0166-2236(99)01399-5","volume":"22","author":"Rupprecht","year":"1999","journal-title":"Trends Neurosci."},{"key":"10.1074\/jbc.M202592200_bib10","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/BF02088174","volume":"16","author":"Lambert","year":"1996","journal-title":"Cell Mol. Neurobiol."},{"key":"10.1074\/jbc.M202592200_bib11","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/0304-3940(92)90327-4","volume":"141","author":"Irwin","year":"1992","journal-title":"Neurosci. Lett."},{"key":"10.1074\/jbc.M202592200_bib12","first-page":"333","volume":"40","author":"Wu","year":"1991","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib13","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1124\/mol.52.6.1113","volume":"52","author":"Park-Chung","year":"1997","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib14","first-page":"813","volume":"43","author":"Bowlby","year":"1993","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib15","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1523\/JNEUROSCI.14-04-01963.1994","volume":"14","author":"ffrench-Mullen","year":"1994","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M202592200_bib16","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0021-5198(19)30781-4","volume":"81","author":"Maurice","year":"1999","journal-title":"Jpn. J. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib17","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0922-4106(90)90004-H","volume":"188","author":"McCann","year":"1990","journal-title":"Eur. J. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib18","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/S0165-6147(96)01037-1","volume":"18","author":"Moebius","year":"1997","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1074\/jbc.M202592200_bib19","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1006\/bbrc.1996.1842","volume":"229","author":"Kekuda","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M202592200_bib20","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1006\/bbrc.1997.7840","volume":"241","author":"Seth","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M202592200_bib21","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1046\/j.1471-4159.1998.70030922.x","volume":"70","author":"Seth","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1074\/jbc.M202592200_bib22","doi-asserted-by":"crossref","first-page":"8072","DOI":"10.1073\/pnas.93.15.8072","volume":"93","author":"Hanner","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib23","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/S0006-2952(01)00666-9","volume":"62","author":"Mei","year":"2001","journal-title":"Biochem. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib24","doi-asserted-by":"crossref","first-page":"16871","DOI":"10.1021\/bi961996m","volume":"35","author":"Moebius","year":"1996","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M202592200_bib25","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0168-0102(01)00258-9","volume":"41","author":"Ueda","year":"2001","journal-title":"Neurosci. Res."},{"key":"10.1074\/jbc.M202592200_bib26","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0304-3940(97)00657-5","volume":"233","author":"Tokuyama","year":"1997","journal-title":"Neurosci. Lett."},{"key":"10.1074\/jbc.M202592200_bib27","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0304-3940(99)00387-0","volume":"268","author":"Tokuyama","year":"1999","journal-title":"Neurosci. Lett."},{"key":"10.1074\/jbc.M202592200_bib28","doi-asserted-by":"crossref","first-page":"3774","DOI":"10.1073\/pnas.92.9.3774","volume":"92","author":"Monnet","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib29","doi-asserted-by":"crossref","first-page":"10231","DOI":"10.1523\/JNEUROSCI.18-24-10231.1998","volume":"18","author":"Li","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M202592200_bib30","doi-asserted-by":"crossref","first-page":"38268","DOI":"10.1074\/jbc.M004136200","volume":"275","author":"Costa","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M202592200_bib31","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1152\/jn.1990.64.5.1390","volume":"64","author":"Segal","year":"1990","journal-title":"J. Neurophysiol."},{"key":"10.1074\/jbc.M202592200_bib32","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1113\/jphysiol.1995.sp020948","volume":"488","author":"Mennerick","year":"1995","journal-title":"J. Physiol."},{"key":"10.1074\/jbc.M202592200_bib33","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1021\/jm980148h","volume":"41","author":"Nilsson","year":"1998","journal-title":"J. Med. Chem."},{"key":"10.1074\/jbc.M202592200_bib34","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1152\/jn.1999.82.3.1286","volume":"82","author":"Sullivan","year":"1999","journal-title":"J. Neurophysiol."},{"key":"10.1074\/jbc.M202592200_bib35","first-page":"788","volume":"293","author":"Hayashi","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M202592200_bib36","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0304-3940(01)01613-5","volume":"301","author":"Partridge","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1074\/jbc.M202592200_bib37","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0006-8993(96)00751-2","volume":"733","author":"Rhodes","year":"1996","journal-title":"Brain Res."},{"key":"10.1074\/jbc.M202592200_bib38","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1046\/j.1471-4159.1998.71052018.x","volume":"71","author":"Darnaudery","year":"1998","journal-title":"J. Neurochem."},{"key":"10.1074\/jbc.M202592200_bib39","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0006-8993(99)01964-2","volume":"852","author":"Darnaudery","year":"2000","journal-title":"Brain Res."},{"key":"10.1074\/jbc.M202592200_bib40","doi-asserted-by":"crossref","first-page":"3757","DOI":"10.1046\/j.1460-9568.1999.00816.x","volume":"11","author":"Barrot","year":"1999","journal-title":"Eur. J. Neurosci."},{"key":"10.1074\/jbc.M202592200_bib41","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/S0006-8993(97)00872-X","volume":"772","author":"Teschemacher","year":"1997","journal-title":"Brain Res."},{"key":"10.1074\/jbc.M202592200_bib42","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1126\/science.2832949","volume":"240","author":"Su","year":"1988","journal-title":"Science"},{"key":"10.1074\/jbc.M202592200_bib43","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1038\/sj.bjp.0704355","volume":"134","author":"Maurice","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib44","doi-asserted-by":"crossref","first-page":"8196","DOI":"10.1073\/pnas.96.14.8196","volume":"96","author":"Morin-Surun","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib45","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S0165-6147(00)01740-5","volume":"22","author":"Su","year":"2001","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1074\/jbc.M202592200_bib46","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1073\/pnas.98.2.491","volume":"98","author":"Hayashi","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M202592200_bib47","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/0304-3940(96)12711-7","volume":"211","author":"Brent","year":"1996","journal-title":"Neurosci. Lett."},{"key":"10.1074\/jbc.M202592200_bib48","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1046\/j.1471-4159.1997.68052201.x","volume":"68","author":"Brent","year":"1997","journal-title":"J. Neurochem."},{"key":"10.1074\/jbc.M202592200_bib49","first-page":"900","volume":"292","author":"Vilner","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M202592200_bib50","doi-asserted-by":"crossref","first-page":"3379","DOI":"10.1046\/j.1460-9568.1998.00342.x","volume":"10","author":"Savic","year":"1998","journal-title":"Eur. J. Neurosci."},{"key":"10.1074\/jbc.M202592200_bib51","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0896-6273(01)00190-8","volume":"29","author":"Emptage","year":"2001","journal-title":"Neuron"},{"key":"10.1074\/jbc.M202592200_bib52","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1097\/00001756-200107200-00032","volume":"12","author":"Han","year":"2001","journal-title":"Neuroreport"},{"key":"10.1074\/jbc.M202592200_bib53","doi-asserted-by":"crossref","first-page":"7896","DOI":"10.1523\/JNEUROSCI.20-21-07896.2000","volume":"20","author":"Perroy","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M202592200_bib54","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0014-2999(95)00208-3","volume":"280","author":"Matsumoto","year":"1995","journal-title":"Eur. J. Pharmacol."},{"key":"10.1074\/jbc.M202592200_bib55","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0165-0173(01)00112-6","volume":"37","author":"Maurice","year":"2001","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1074\/jbc.M202592200_bib56","doi-asserted-by":"crossref","first-page":"3578","DOI":"10.1210\/endo.142.8.8327","volume":"142","author":"Kimoto","year":"2001","journal-title":"Endocrinology"},{"key":"10.1074\/jbc.M202592200_bib57","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1046\/j.1460-9568.1998.00191.x","volume":"10","author":"Guarneri","year":"1998","journal-title":"Eur. J. Neurosci."},{"key":"10.1074\/jbc.M202592200_bib58","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1126\/science.287.5454.864","volume":"287","author":"Verhage","year":"2000","journal-title":"Science"},{"key":"10.1074\/jbc.M202592200_bib59","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1126\/science.1064335","volume":"294","author":"Schoch","year":"2001","journal-title":"Science"},{"key":"10.1074\/jbc.M202592200_bib60","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/nn783","volume":"5","author":"Washbourne","year":"2002","journal-title":"Nat. Neurosci."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820702723?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820702723?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M202592200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T12:44:11Z","timestamp":1641386651000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820702723"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8]]},"references-count":60,"journal-issue":{"issue":"32","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["S0021925820702723"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m202592200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2002,8]]}}}