{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:24:55Z","timestamp":1790400295300,"version":"4.1.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"34","license":[{"start":{"date-parts":[[2002,8,1]],"date-time":"2002-08-01T00:00:00Z","timestamp":1028160000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T00:00:00Z","timestamp":1603843200000},"content-version":"vor","delay-in-days":6663,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2002,8]]},"DOI":"10.1074\/jbc.m203801200","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T17:58:01Z","timestamp":1032371881000},"page":"30515-30523","source":"Crossref","is-referenced-by-count":99,"title":["Functional Link between BLM Defective in Bloom's Syndrome and the Ataxia-telangiectasia-mutated Protein, ATM"],"prefix":"10.1016","volume":"277","author":[{"given":"Heather","family":"Beamish","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padmini","family":"Kedar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Fukao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergei","family":"Beresten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuri","family":"Gueven","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Purdie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Lees-Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin F.","family":"Lavin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M203801200_bib1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/00005792-199311000-00003","volume":"72","author":"German","year":"1993","journal-title":"Medicine (Baltimore)"},{"key":"10.1074\/jbc.M203801200_bib2","first-page":"1019","volume":"57","author":"Ellis","year":"1995","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/jbc.M203801200_bib3","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1073\/pnas.72.2.758","volume":"72","author":"Hand","year":"1975","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M203801200_bib4","first-page":"3141","volume":"50","author":"Lonn","year":"1990","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M203801200_bib5","first-page":"197","volume":"183","author":"Kurihara","year":"1987","journal-title":"Mutat. Res."},{"key":"10.1074\/jbc.M203801200_bib6","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0165-4608(85)90006-8","volume":"16","author":"Aurias","year":"1985","journal-title":"Cancer Genet. Cytogenet."},{"key":"10.1074\/jbc.M203801200_bib7","first-page":"8391","volume":"14","author":"Gangloff","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M203801200_bib8","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1126\/science.272.5259.258","volume":"272","author":"Yu","year":"1996","journal-title":"Science"},{"key":"10.1074\/jbc.M203801200_bib9","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1093\/emboj\/16.10.2682","volume":"16","author":"Stewart","year":"1997","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M203801200_bib10","doi-asserted-by":"crossref","first-page":"30611","DOI":"10.1074\/jbc.272.49.30611","volume":"272","author":"Karow","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M203801200_bib11","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1091\/mbc.10.3.665","volume":"10","author":"Neff","year":"1999","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M203801200_bib12","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1083\/jcb.147.2.221","volume":"147","author":"Ishov","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M203801200_bib13","doi-asserted-by":"crossref","first-page":"5214","DOI":"10.1073\/pnas.090525897","volume":"97","author":"Yankiwski","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M203801200_bib14","doi-asserted-by":"crossref","first-page":"2731","DOI":"10.1038\/sj.onc.1203595","volume":"19","author":"Dutertre","year":"2000","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M203801200_bib15","doi-asserted-by":"crossref","first-page":"2570","DOI":"10.1101\/gad.822400","volume":"14","author":"Liao","year":"2000","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M203801200_bib16","doi-asserted-by":"crossref","first-page":"3428","DOI":"10.1093\/emboj\/19.13.3428","volume":"19","author":"Wang","year":"2000","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M203801200_bib17","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1101\/gad.14.8.927","volume":"14","author":"Wang","year":"2000","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M203801200_bib18","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1126\/science.7792600","volume":"268","author":"Savitsky","year":"1995","journal-title":"Science."},{"key":"10.1074\/jbc.M203801200_bib19","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0092-8674(00)81175-7","volume":"93","author":"Carney","year":"1998","journal-title":"Cell."},{"key":"10.1074\/jbc.M203801200_bib20","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/549","volume":"19","author":"Matsuura","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M203801200_bib21","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0092-8674(00)81174-5","volume":"93","author":"Varon","year":"1998","journal-title":"Cell"},{"key":"10.1074\/jbc.M203801200_bib22","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0092-8674(00)81547-0","volume":"99","author":"Stewart","year":"1999","journal-title":"Cell."},{"key":"10.1074\/jbc.M203801200_bib23","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/75508","volume":"25","author":"Gatei","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M203801200_bib24","doi-asserted-by":"crossref","first-page":"19513","DOI":"10.1074\/jbc.274.28.19513","volume":"274","author":"Dong","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M203801200_bib25","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/35013083","volume":"405","author":"Zhao","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M203801200_bib26","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1042\/bst0290661","volume":"29","author":"Shiloh","year":"2001","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M203801200_bib27","doi-asserted-by":"crossref","first-page":"2177","DOI":"10.1101\/gad.914401","volume":"15","author":"Abraham","year":"2001","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M203801200_bib28","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1126\/science.281.5383.1674","volume":"281","author":"Banin","year":"1998","journal-title":"Science"},{"key":"10.1074\/jbc.M203801200_bib29","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1126\/science.281.5383.1677","volume":"281","author":"Canman","year":"1998","journal-title":"Science"},{"key":"10.1074\/jbc.M203801200_bib30","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/3882","volume":"20","author":"Khanna","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M203801200_bib31","doi-asserted-by":"crossref","first-page":"13777","DOI":"10.1073\/pnas.96.24.13777","volume":"96","author":"Chebab","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M203801200_bib32","doi-asserted-by":"crossref","first-page":"10389","DOI":"10.1073\/pnas.190030497","volume":"97","author":"Matsuoka","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M203801200_bib33","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/0092-8674(92)90593-2","volume":"71","author":"Kastan","year":"1992","journal-title":"Cell"},{"key":"10.1074\/jbc.M203801200_bib34","doi-asserted-by":"crossref","first-page":"5214","DOI":"10.1128\/MCB.21.15.5214-5222.2001","volume":"21","author":"Buscemi","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M203801200_bib35","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/09553009414550211","volume":"65","author":"Beamish","year":"1994","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1074\/jbc.M203801200_bib36","doi-asserted-by":"crossref","first-page":"3445","DOI":"10.1128\/MCB.21.10.3445-3450.2001","volume":"21","author":"Xu","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M203801200_bib37","doi-asserted-by":"crossref","first-page":"8021","DOI":"10.1073\/pnas.94.15.8021","volume":"94","author":"Zhang","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M203801200_bib38","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S0960-9822(99)80264-4","volume":"9","author":"Karow","year":"1999","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M203801200_bib39","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/hmg\/5.4.433","volume":"5","author":"Gilad","year":"1996","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M203801200_bib40","first-page":"3299","volume":"60","author":"Gatei","year":"2000","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M203801200_bib41","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1146\/annurev.immunol.15.1.177","volume":"15","author":"Lavin","year":"1997","journal-title":"Annu. Rev. Immunol."},{"key":"10.1074\/jbc.M203801200_bib42","doi-asserted-by":"crossref","first-page":"37538","DOI":"10.1074\/jbc.274.53.37538","volume":"274","author":"Kim","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M203801200_bib43","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/35007091","volume":"404","author":"Lim","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M203801200_bib44","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/35013089","volume":"405","author":"Wu","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M203801200_bib45","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1080\/02841860152619089","volume":"40","author":"Kastan","year":"2001","journal-title":"Acta Oncol."},{"key":"10.1074\/jbc.M203801200_bib46","doi-asserted-by":"crossref","first-page":"5955","DOI":"10.1038\/sj.onc.1204003","volume":"19","author":"Ababou","year":"2000","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M203801200_bib47","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1083\/jcb.153.2.367","volume":"153","author":"Bischof","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M203801200_bib48","doi-asserted-by":"crossref","first-page":"19375","DOI":"10.1074\/jbc.M009471200","volume":"276","author":"Wu","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M203801200_bib49","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1083\/jcb.200110009","volume":"157","author":"Franchitto","year":"2002","journal-title":"J. Cell Biol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820701262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820701262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M203801200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T12:39:27Z","timestamp":1641386367000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820701262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,8]]},"references-count":49,"journal-issue":{"issue":"34","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["S0021925820701262"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m203801200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2002,8]]}}}