{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T20:07:27Z","timestamp":1791144447044,"version":"4.1.0"},"reference-count":69,"publisher":"Elsevier BV","issue":"40","license":[{"start":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T00:00:00Z","timestamp":1033430400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T00:00:00Z","timestamp":1603152000000},"content-version":"vor","delay-in-days":6594,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2002,10]]},"DOI":"10.1074\/jbc.m206644200","type":"journal-article","created":{"date-parts":[[2002,9,27]],"date-time":"2002-09-27T20:02:47Z","timestamp":1033156967000},"page":"37881-37887","source":"Crossref","is-referenced-by-count":176,"title":["Absence of Small Conductance K+ Channel (SK) Activity in Apical Membranes of Thick Ascending Limb and Cortical Collecting Duct in ROMK (Bartter's) Knockout Mice"],"prefix":"10.1016","volume":"277","author":[{"given":"Ming","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingshang","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinbo","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Knepper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"WenHui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Giebisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary E.","family":"Shull","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven C.","family":"Hebert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M206644200_bib1","first-page":"F817","volume":"274","author":"Giebisch","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/BF00584588","volume":"392","author":"Greger","year":"1981","journal-title":"Pfluegers Arch."},{"key":"10.1074\/jbc.M206644200_bib3","first-page":"119","volume":"40 Suppl. 33","author":"Greger","year":"1991","journal-title":"Kidney Int."},{"key":"10.1074\/jbc.M206644200_bib4","first-page":"F745","volume":"246","author":"Hebert","year":"1984","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib5","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1085\/jgp.87.4.567","volume":"87","author":"Hebert","year":"1986","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M206644200_bib6","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/362031a0","volume":"362","author":"Ho","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M206644200_bib7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1146\/annurev.physiol.59.1.171","volume":"59","author":"Nichols","year":"1997","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.M206644200_bib8","doi-asserted-by":"crossref","first-page":"C809","DOI":"10.1152\/ajpcell.1994.266.3.C809","volume":"266","author":"Zhou","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib9","first-page":"F1132","volume":"268","author":"Boim","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib10","doi-asserted-by":"crossref","first-page":"F1124","DOI":"10.1152\/ajpcell.1995.268.1.C127","volume":"268","author":"Lee","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib11","doi-asserted-by":"crossref","first-page":"24261","DOI":"10.1016\/S0021-9258(19)51076-6","volume":"269","author":"Shuck","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M206644200_bib12","first-page":"F739","volume":"273","author":"Xu","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib13","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1046\/j.1523-1755.1998.00120.x","volume":"54","author":"Kohda","year":"1998","journal-title":"Kidney Int."},{"key":"10.1074\/jbc.M206644200_bib14","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1681\/ASN.V8121823","volume":"8","author":"Mennitt","year":"1997","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1074\/jbc.M206644200_bib15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev.physiol.59.1.413","volume":"59","author":"Wang","year":"1997","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.M206644200_bib16","doi-asserted-by":"crossref","first-page":"F404","DOI":"10.1152\/ajpcell.1997.273.2.C404","volume":"273","author":"Palmer","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib17","doi-asserted-by":"crossref","first-page":"9313","DOI":"10.1074\/jbc.271.16.9313","volume":"271","author":"Xu","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M206644200_bib18","doi-asserted-by":"crossref","first-page":"8077","DOI":"10.1073\/pnas.91.17.8077","volume":"91","author":"McNicholas","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M206644200_bib19","first-page":"F516","volume":"273","author":"Choe","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib20","doi-asserted-by":"crossref","first-page":"4093","DOI":"10.1002\/j.1460-2075.1996.tb00784.x","volume":"15","author":"Fakler","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M206644200_bib21","doi-asserted-by":"crossref","first-page":"7156","DOI":"10.1074\/jbc.M008671200","volume":"276","author":"Moral","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M206644200_bib22","doi-asserted-by":"crossref","first-page":"20502","DOI":"10.1074\/jbc.M000783200","volume":"275","author":"Wei","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M206644200_bib23","first-page":"F165","volume":"278","author":"Wang","year":"2000","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib24","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/0002-9343(62)90214-0","volume":"33","author":"Bartter","year":"1962","journal-title":"Am. J. Med."},{"key":"10.1074\/jbc.M206644200_bib25","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1146\/annurev.me.31.020180.002201","volume":"31","author":"Gill","year":"1980","journal-title":"Annu. Rev. Med."},{"key":"10.1074\/jbc.M206644200_bib26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/ki.1985.123","volume":"28","author":"Stein","year":"1985","journal-title":"Kidney Int."},{"key":"10.1074\/jbc.M206644200_bib27","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1080\/21548331.1994.11443023","volume":"29","author":"Gordon","year":"1994","journal-title":"Hosp. Pract."},{"key":"10.1074\/jbc.M206644200_bib28","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0002-9343(98)00196-X","volume":"105","author":"Guay-Woodford","year":"1998","journal-title":"Am. J. Med."},{"key":"10.1074\/jbc.M206644200_bib29","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s001090050223","volume":"76","author":"Karolyi","year":"1998","journal-title":"J. Mol. Med."},{"key":"10.1074\/jbc.M206644200_bib30","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1530\/eje.0.1370613","volume":"137","author":"Asteria","year":"1997","journal-title":"Eur. J. Endocrinol."},{"key":"10.1074\/jbc.M206644200_bib31","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0955-0674(98)80057-4","volume":"10","author":"Simon","year":"1998","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M206644200_bib32","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/ng0696-183","volume":"13","author":"Simon","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M206644200_bib33","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/ng1097-171","volume":"17","author":"Simon","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M206644200_bib34","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/35107099","volume":"414","author":"Estevez","year":"2001","journal-title":"Nature"},{"key":"10.1074\/jbc.M206644200_bib35","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ng752","volume":"29","author":"Birkenhager","year":"2001","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M206644200_bib36","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1038\/ng1096-152","volume":"14","author":"Simon","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M206644200_bib37","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/hmg\/6.1.17","volume":"6","author":"Karolyil","year":"1997","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M206644200_bib38","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s004670050408","volume":"12","author":"Vollmer","year":"1998","journal-title":"Pediatr. Nephrol."},{"key":"10.1074\/jbc.M206644200_bib39","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1093\/hmg\/7.6.975","volume":"7","author":"Schwalbe","year":"1998","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M206644200_bib40","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1006\/bbrc.1996.6024","volume":"230","author":"Derst","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M206644200_bib41","doi-asserted-by":"crossref","first-page":"23884","DOI":"10.1074\/jbc.273.37.23884","volume":"273","author":"Derst","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M206644200_bib42","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1085\/jgp.114.5.685","volume":"114","author":"Flagg","year":"1999","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M206644200_bib43","first-page":"F739","volume":"273","author":"Xu","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib44","doi-asserted-by":"crossref","first-page":"F289","DOI":"10.1152\/ajpcell.1997.273.1.C289","volume":"273","author":"Biemesderfer","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib45","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1681\/ASN.V12110","volume":"12","author":"Ecelbarger","year":"2001","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1074\/jbc.M206644200_bib46","first-page":"F298","volume":"277","author":"Wang","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib47","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1085\/jgp.116.2.299","volume":"116","author":"Lu","year":"2000","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M206644200_bib48","doi-asserted-by":"crossref","first-page":"5434","DOI":"10.1073\/pnas.090091297","volume":"97","author":"Takahashi","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M206644200_bib49","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000025957","volume":"23","author":"Lu","year":"2000","journal-title":"Kidney Blood Press. Res."},{"key":"10.1074\/jbc.M206644200_bib50","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/0002-9343(78)90794-5","volume":"65","author":"Gill","year":"1978","journal-title":"Am. J. Med."},{"key":"10.1074\/jbc.M206644200_bib51","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/0272-6386(95)90137-X","volume":"25","author":"Tsukamoto","year":"1995","journal-title":"Am. J. Kidney Dis."},{"key":"10.1074\/jbc.M206644200_bib52","first-page":"F1013","volume":"250","author":"Velazquez","year":"1986","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib53","first-page":"F192","volume":"236\u20135","author":"Good","year":"1979","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib54","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev.ph.54.030192.000501","volume":"54","author":"Wang","year":"1992","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.M206644200_bib55","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1085\/jgp.98.1.35","volume":"98","author":"Wang","year":"1991","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M206644200_bib56","first-page":"F143","volume":"256","author":"Frindt","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib57","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1042\/bj3300287","volume":"330","author":"Hebert","year":"1998","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M206644200_bib58","first-page":"F825","volume":"276","author":"Zolotnitskaya","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib59","first-page":"F599","volume":"267","author":"Wang","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib60","doi-asserted-by":"crossref","first-page":"C121","DOI":"10.1152\/ajpcell.1987.252.2.C121","volume":"252","author":"Guggino","year":"1987","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib61","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1085\/jgp.108.6.537","volume":"108","author":"Lu","year":"1996","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M206644200_bib62","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1085\/jgp.106.4.727","volume":"106","author":"Wang","year":"1995","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M206644200_bib63","first-page":"F458","volume":"252","author":"Frindt","year":"1987","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib64","doi-asserted-by":"crossref","first-page":"14738","DOI":"10.1016\/S0021-9258(18)77174-3","volume":"265","author":"DeJongh","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M206644200_bib65","first-page":"F786","volume":"280","author":"Woda","year":"2001","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib66","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s002329900391","volume":"164","author":"Taniguchi","year":"1998","journal-title":"J. Membr. Biol."},{"key":"10.1074\/jbc.M206644200_bib67","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/ki.1985.154","volume":"28","author":"Hropot","year":"1985","journal-title":"Kidney Int."},{"key":"10.1074\/jbc.M206644200_bib68","doi-asserted-by":"crossref","first-page":"F555","DOI":"10.1152\/ajpcell.1987.253.4.C555","volume":"253","author":"Velazquez","year":"1987","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M206644200_bib69","doi-asserted-by":"crossref","first-page":"37871","DOI":"10.1074\/jbc.M205627200","volume":"277","author":"Lorenz","year":"2002","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818365207?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925818365207?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M206644200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,28]],"date-time":"2021-05-28T06:04:52Z","timestamp":1622181892000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925818365207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":69,"journal-issue":{"issue":"40","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["S0021925818365207"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m206644200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}