{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:47:59Z","timestamp":1790545679285,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T00:00:00Z","timestamp":1602720000000},"content-version":"vor","delay-in-days":6497,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2003,1]]},"DOI":"10.1074\/jbc.m211131200","type":"journal-article","created":{"date-parts":[[2003,1,17]],"date-time":"2003-01-17T21:11:58Z","timestamp":1042837918000},"page":"2341-2347","source":"Crossref","is-referenced-by-count":59,"title":["Interaction of Nitric Oxide with Human Heme Oxygenase-1"],"prefix":"10.1016","volume":"278","author":[{"given":"Jinling","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shen","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Mo\u00ebnne-Loccoz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul R.","family":"Ortiz de Montellano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M211131200_bib1","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0891-5849(98)00092-6","volume":"25","author":"Wink","year":"1998","journal-title":"Free Radic. Biol. Med."},{"key":"10.1074\/jbc.M211131200_bib2","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1002\/(SICI)1521-3773(19990712)38:13\/14<1856::AID-ANIE1856>3.0.CO;2-D","volume":"38","author":"Murad","year":"1999","journal-title":"Angew. Chem. Int. Ed. Engl."},{"key":"10.1074\/jbc.M211131200_bib3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1146\/annurev.pa.35.040195.001241","volume":"35","author":"Zhang","year":"1995","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1074\/jbc.M211131200_bib4","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0165-0173(97)00032-5","volume":"26","author":"Snyder","year":"1998","journal-title":"Brain Res. Rev."},{"key":"10.1074\/jbc.M211131200_bib5","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0021-9258(17)42488-4","volume":"261","author":"Maines","year":"1986","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib6","doi-asserted-by":"crossref","first-page":"7865","DOI":"10.1073\/pnas.82.23.7865","volume":"240","author":"Shibahara","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M211131200_bib7","doi-asserted-by":"crossref","first-page":"7501","DOI":"10.1016\/S0021-9258(19)39141-0","volume":"265","author":"Rotenberg","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib8","series-title":"Heme Oxygenase: Clinical Applications and Functions","author":"Maines","year":"1992"},{"key":"10.1074\/jbc.M211131200_bib9","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1161\/01.RES.88.5.506","volume":"88","author":"Ishikawa","year":"2001","journal-title":"Circ. Res."},{"key":"10.1074\/jbc.M211131200_bib10","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1042\/bj3530459","volume":"353","author":"Hanselmann","year":"2001","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M211131200_bib11","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/89068","volume":"7","author":"Duckers","year":"2001","journal-title":"Nat. Med."},{"key":"10.1074\/jbc.M211131200_bib12","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1046\/j.1523-1755.2001.00471.x","volume":"59","author":"Nath","year":"2001","journal-title":"Kidney Int."},{"key":"10.1074\/jbc.M211131200_bib13","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1042\/bj3480615","volume":"348","author":"Clark","year":"2000","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M211131200_bib14","first-page":"L1029","volume":"279","author":"Otterbein","year":"2000","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M211131200_bib15","doi-asserted-by":"crossref","first-page":"14848","DOI":"10.1073\/pnas.94.26.14848","volume":"94","author":"Zakhary","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M211131200_bib16","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0165-6147(97)90622-2","volume":"18","author":"Grundemar","year":"1997","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1074\/jbc.M211131200_bib17","doi-asserted-by":"crossref","first-page":"F728","DOI":"10.1152\/ajpcell.2000.279.6.C1733","volume":"279","author":"Liang","year":"2000","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M211131200_bib18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/sj.bjp.0703281","volume":"130","author":"Alcaraz","year":"2000","journal-title":"Br. J. Pharmacol."},{"key":"10.1074\/jbc.M211131200_bib19","first-page":"L980","volume":"273","author":"Hartsfield","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M211131200_bib20","first-page":"609","volume":"46","author":"Chen","year":"2000","journal-title":"Cell. Mol. Biol."},{"key":"10.1074\/jbc.M211131200_bib21","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1161\/01.ATV.20.5.1209","volume":"20","author":"Polte","year":"2000","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1074\/jbc.M211131200_bib22","doi-asserted-by":"crossref","first-page":"1734","DOI":"10.1046\/j.1523-1755.1999.00429.x","volume":"55","author":"Datta","year":"1999","journal-title":"Kidney Int."},{"key":"10.1074\/jbc.M211131200_bib23","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/(SICI)1098-1136(199802)22:2<138::AID-GLIA5>3.0.CO;2-3","volume":"22","author":"Kitamura","year":"1998","journal-title":"Glia"},{"key":"10.1074\/jbc.M211131200_bib24","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1093\/oxfordjournals.jbchem.a021710","volume":"121","author":"Takahashi","year":"1997","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1074\/jbc.M211131200_bib25","doi-asserted-by":"crossref","first-page":"18411","DOI":"10.1074\/jbc.272.29.18411","volume":"272","author":"Foresti","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib26","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1021\/tx970041h","volume":"10","author":"Thom","year":"1997","journal-title":"Chem. Res. Toxicol."},{"key":"10.1074\/jbc.M211131200_bib27","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1136\/gut.47.6.771","volume":"47","author":"Cavicchi","year":"2000","journal-title":"Gut"},{"key":"10.1074\/jbc.M211131200_bib28","doi-asserted-by":"crossref","first-page":"2540","DOI":"10.1681\/ASN.V10122540","volume":"10","author":"Datta","year":"1999","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1074\/jbc.M211131200_bib29","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1016\/S0923-2494(99)80050-9","volume":"149","author":"Turcanu","year":"1998","journal-title":"Res. Immunol."},{"key":"10.1074\/jbc.M211131200_bib30","doi-asserted-by":"crossref","first-page":"14151","DOI":"10.1021\/bi00214a012","volume":"32","author":"Sun","year":"1993","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M211131200_bib31","doi-asserted-by":"crossref","first-page":"6345","DOI":"10.1074\/jbc.270.11.6345","volume":"270","author":"Ishikawa","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib32","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1046\/j.1432-1327.1999.00677.x","volume":"264","author":"Ding","year":"1999","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M211131200_bib33","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1006\/bbrc.1995.2406","volume":"214","author":"Willis","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M211131200_bib34","doi-asserted-by":"crossref","first-page":"19976","DOI":"10.1016\/S0021-9258(18)54879-1","volume":"266","author":"Shen","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib35","doi-asserted-by":"crossref","first-page":"5297","DOI":"10.1074\/jbc.275.8.5297","volume":"275","author":"Liu","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib36","doi-asserted-by":"crossref","first-page":"10612","DOI":"10.1074\/jbc.M010349200","volume":"276","author":"Lightning","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib37","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1021\/bi00013a034","volume":"34","author":"Wilks","year":"1995","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M211131200_bib38","series-title":"Molecular Cloning: A Laboratory Manual","author":"Sambrook","year":"1989"},{"key":"10.1074\/jbc.M211131200_bib39","doi-asserted-by":"crossref","first-page":"34501","DOI":"10.1074\/jbc.M004245200","volume":"275","author":"Liu","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib40","doi-asserted-by":"crossref","first-page":"22357","DOI":"10.1016\/S0021-9258(18)41536-0","volume":"268","author":"Wilks","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib41","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/0076-6879(93)26020-A","volume":"226","author":"Loehr","year":"1993","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M211131200_bib42","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1021\/ar9700116","volume":"32","author":"Scheidt","year":"1999","journal-title":"Acc. Chem. Res."},{"key":"10.1074\/jbc.M211131200_bib43","doi-asserted-by":"crossref","first-page":"7042","DOI":"10.1073\/pnas.80.22.7042","volume":"80","author":"Benko","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M211131200_bib45","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1111\/j.1432-1033.1995.tb20798.x","volume":"232","author":"Brown","year":"1995","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M211131200_bib46","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S0005-2728(99)00021-3","volume":"1411","author":"Cooper","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M211131200_bib47","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/12319","volume":"6","author":"Schuller","year":"1999","journal-title":"Nat. Struct. Biol."},{"key":"10.1074\/jbc.M211131200_bib48","doi-asserted-by":"crossref","first-page":"8311","DOI":"10.1021\/ja0002868","volume":"122","author":"Zhou","year":"2000","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M211131200_bib49","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1021\/ja001696z","volume":"123","author":"Laverman","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M211131200_bib50","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0010-8545(98)00228-8","volume":"187","author":"Hoshino","year":"1999","journal-title":"Coord. Chem. Rev."},{"key":"10.1074\/jbc.M211131200_bib51","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1016\/S0021-9258(17)33557-3","volume":"251","author":"Moore","year":"1976","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib52","doi-asserted-by":"crossref","first-page":"12199","DOI":"10.1021\/bi962744o","volume":"36","author":"Miller","year":"1997","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M211131200_bib53","doi-asserted-by":"crossref","first-page":"4104","DOI":"10.1021\/bi00362a018","volume":"25","author":"Addison","year":"1986","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M211131200_bib54","doi-asserted-by":"crossref","first-page":"4816","DOI":"10.1074\/jbc.275.7.4816","volume":"275","author":"Shimizu","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211131200_bib55","doi-asserted-by":"crossref","first-page":"11327","DOI":"10.1021\/bi0109257","volume":"40","author":"Roberts","year":"2001","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M211131200_bib56","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/76769","volume":"7","author":"Weichsel","year":"2000","journal-title":"Nat. Struct. Biol."},{"key":"10.1074\/jbc.M211131200_bib57","doi-asserted-by":"crossref","first-page":"5377","DOI":"10.1021\/bi00591a019","volume":"18","author":"Asher","year":"1979","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M211131200_bib58","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1021\/cr00027a007","volume":"94","author":"Spinger","year":"1994","journal-title":"Chem. Rev."},{"key":"10.1074\/jbc.M211131200_bib59","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1038\/358676a0","volume":"358","author":"Malinski","year":"1992","journal-title":"Nature"},{"key":"10.1074\/jbc.M211131200_bib60","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/jcbfm.1993.48","volume":"13","author":"Malinski","year":"1993","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1074\/jbc.M211131200_bib61","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1006\/bbrc.1993.1914","volume":"194","author":"Malinski","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M211131200_bib62","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1006\/bbrc.1993.1735","volume":"193","author":"Malinski","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M211131200_bib63","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1006\/bbrc.1993.1685","volume":"193","author":"Tsukahara","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M211131200_bib64","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0168-0102(90)90048-J","volume":"9","author":"Shibuki","year":"1990","journal-title":"Neurosci. Res."},{"key":"10.1074\/jbc.M211131200_bib65","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/349326a0","volume":"349","author":"Shibuki","year":"1991","journal-title":"Nature"},{"key":"10.1074\/jbc.M211131200_bib44","doi-asserted-by":"crossref","first-page":"11614","DOI":"10.1021\/ja0113910","volume":"123","author":"Laverman","year":"2001","journal-title":"J. Am. Chem. Soc."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819309901?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819309901?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M211131200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T19:31:51Z","timestamp":1639683111000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819309901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":65,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["S0021925819309901"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m211131200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2003,1]]}}}