{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T16:23:56Z","timestamp":1780590236904,"version":"3.54.1"},"reference-count":39,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2003,3,1]],"date-time":"2003-03-01T00:00:00Z","timestamp":1046476800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,10]],"date-time":"2020-10-10T00:00:00Z","timestamp":1602288000000},"content-version":"vor","delay-in-days":6433,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2003,3]]},"DOI":"10.1074\/jbc.m211252200","type":"journal-article","created":{"date-parts":[[2003,3,7]],"date-time":"2003-03-07T18:45:37Z","timestamp":1047062737000},"page":"9267-9275","source":"Crossref","is-referenced-by-count":33,"title":["Approaches to Define Antigen Receptor-induced Serine Kinase Signal Transduction Pathways"],"prefix":"10.1016","volume":"278","author":[{"given":"Emmanuelle","family":"Astoul","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arian D.","family":"Laurence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Totty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Beer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis R.","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doreen A.","family":"Cantrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M211252200_bib1","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1146\/annurev.immunol.18.1.165","volume":"18","author":"Acuto","year":"2000","journal-title":"Annu. Rev. Immunol."},{"key":"10.1074\/jbc.M211252200_bib2","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1146\/annurev.immunol.20.092601.111357","volume":"20","author":"Samelson","year":"2002","journal-title":"Annu. Rev. Immunol."},{"key":"10.1074\/jbc.M211252200_bib3","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/35100523","volume":"1","author":"Koretzky","year":"2001","journal-title":"Nat. Rev. Immunol."},{"key":"10.1074\/jbc.M211252200_bib4","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1006\/smim.2001.0338","volume":"14","author":"Cantrell","year":"2002","journal-title":"Semin. Immunol."},{"key":"10.1074\/jbc.M211252200_bib5","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0952-7915(00)00224-7","volume":"13","author":"Rincon","year":"2001","journal-title":"Curr. Opin. Immunol."},{"key":"10.1074\/jbc.M211252200_bib6","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1084\/jem.191.12.2075","volume":"191","author":"Matthews","year":"2000","journal-title":"J. Exp. Med."},{"key":"10.1074\/jbc.M211252200_bib7","doi-asserted-by":"crossref","first-page":"37246","DOI":"10.1074\/jbc.M007732200","volume":"275","author":"Bertolotto","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211252200_bib8","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0952-7915(99)00056-4","volume":"12","author":"Lanzavecchia","year":"2000","journal-title":"Curr. Opin. Immunol."},{"key":"10.1074\/jbc.M211252200_bib9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/S0014-5793(00)02235-3","volume":"486","author":"Lafont","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M211252200_bib10","doi-asserted-by":"crossref","first-page":"2935","DOI":"10.1093\/emboj\/19.12.2935","volume":"19","author":"Matthews","year":"2000","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M211252200_bib11","doi-asserted-by":"crossref","first-page":"3923","DOI":"10.1002\/j.1460-2075.1996.tb00766.x","volume":"15","author":"Genot","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M211252200_bib12","doi-asserted-by":"crossref","first-page":"11410","DOI":"10.1074\/jbc.271.19.11410","volume":"271","author":"Welsh","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211252200_bib13","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1038\/19328","volume":"398","author":"Kops","year":"1999","journal-title":"Nature"},{"key":"10.1074\/jbc.M211252200_bib14","doi-asserted-by":"crossref","first-page":"5024","DOI":"10.4049\/jimmunol.168.10.5024","volume":"168","author":"Stahl","year":"2002","journal-title":"J. Immunol."},{"key":"10.1074\/jbc.M211252200_bib15","doi-asserted-by":"crossref","first-page":"9138","DOI":"10.1128\/MCB.20.24.9138-9148.2000","volume":"20","author":"Dijkers","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M211252200_bib16","doi-asserted-by":"crossref","first-page":"4360","DOI":"10.1093\/emboj\/20.16.4360","volume":"20","author":"Knebel","year":"2001","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M211252200_bib17","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1093\/emboj\/16.8.1921","volume":"16","author":"Fukunaga","year":"1997","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M211252200_bib18","first-page":"87","volume":"87","author":"Songyang","year":"1998","journal-title":"Methods Mol. Biol."},{"key":"10.1074\/jbc.M211252200_bib19","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/86737","volume":"19","author":"Yaffe","year":"2001","journal-title":"Nat. Biotechnol."},{"key":"10.1074\/jbc.M211252200_bib20","doi-asserted-by":"crossref","first-page":"36108","DOI":"10.1074\/jbc.M005497200","volume":"275","author":"Obata","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211252200_bib21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S1097-2765(02)00568-3","volume":"10","author":"Manning","year":"2002","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M211252200_bib22","doi-asserted-by":"crossref","first-page":"22115","DOI":"10.1074\/jbc.C200198200","volume":"277","author":"Kane","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211252200_bib23","doi-asserted-by":"crossref","first-page":"39379","DOI":"10.1074\/jbc.M206399200","volume":"277","author":"Zhang","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211252200_bib24","doi-asserted-by":"crossref","first-page":"10780","DOI":"10.1016\/S0021-9258(18)82053-1","volume":"268","author":"Reif","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211252200_bib25","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1083\/jcb.145.7.1511","volume":"145","author":"Astoul","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M211252200_bib26","doi-asserted-by":"crossref","first-page":"4729","DOI":"10.1128\/MCB.19.7.4729","volume":"19","author":"Brennan","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M211252200_bib27","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/378785a0","volume":"378","author":"Cross","year":"1995","journal-title":"Nature"},{"key":"10.1074\/jbc.M211252200_bib28","doi-asserted-by":"crossref","first-page":"17184","DOI":"10.1074\/jbc.274.24.17184","volume":"274","author":"Guo","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M211252200_bib29","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1038\/43474","volume":"401","author":"Romashkova","year":"1999","journal-title":"Nature"},{"key":"10.1074\/jbc.M211252200_bib30","first-page":"279","volume":"11","author":"Mirza","year":"2000","journal-title":"Cell Growth & Differ."},{"key":"10.1074\/jbc.M211252200_bib31","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0092-8674(00)80595-4","volume":"96","author":"Brunet","year":"1999","journal-title":"Cell"},{"key":"10.1074\/jbc.M211252200_bib32","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0092-8674(00)80405-5","volume":"91","author":"Datta","year":"1997","journal-title":"Cell"},{"key":"10.1074\/jbc.M211252200_bib33","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1128\/MCB.22.7.2099-2110.2002","volume":"22","author":"Fang","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M211252200_bib34","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/S0014-5793(99)01434-9","volume":"461","author":"Shaw","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M211252200_bib35","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1002\/1615-9861(200104)1:5<641::AID-PROT641>3.0.CO;2-R","volume":"1","author":"Kuster","year":"2001","journal-title":"Proteomics"},{"key":"10.1074\/jbc.M211252200_bib36","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0167-4781(01)00242-1","volume":"1520","author":"Beer","year":"2001","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M211252200_bib37","first-page":"453","volume":"9","author":"Kim","year":"2002","journal-title":"Nat. Struct. Biol."},{"key":"10.1074\/jbc.M211252200_bib38","doi-asserted-by":"crossref","first-page":"5373","DOI":"10.1038\/sj.onc.1204698","volume":"20","author":"Claudio","year":"2001","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M211252200_bib39","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1006\/bbrc.2001.5722","volume":"288","author":"Uchida","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192581971299X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192581971299X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M211252200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,3]],"date-time":"2022-01-03T19:08:26Z","timestamp":1641236906000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002192581971299X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,3]]},"references-count":39,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2003,3]]}},"alternative-id":["S002192581971299X"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m211252200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2003,3]]}}}