{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:20:53Z","timestamp":1790893253669,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2003,5,1]],"date-time":"2003-05-01T00:00:00Z","timestamp":1051747200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T00:00:00Z","timestamp":1601596800000},"content-version":"vor","delay-in-days":6364,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2003,5]]},"DOI":"10.1074\/jbc.m300611200","type":"journal-article","created":{"date-parts":[[2003,5,9]],"date-time":"2003-05-09T21:41:36Z","timestamp":1052516496000},"page":"18419-18425","source":"Crossref","is-referenced-by-count":76,"title":["Resistance to \u03b2-Lactam Antibiotics and Its Mediation by the Sensor Domain of the Transmembrane BlaR Signaling Pathway in Staphylococcus aureus"],"prefix":"10.1016","volume":"278","author":[{"given":"Dasantila","family":"Golemi-Kotra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joo Young","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samy O.","family":"Meroueh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergei B.","family":"Vakulenko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahriar","family":"Mobashery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M300611200_bib1","series-title":"The Staphylococci in Human Disease","first-page":"309","author":"Boyce","year":"1997"},{"key":"10.1074\/jbc.M300611200_bib2","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S1286-4579(01)01414-9","volume":"7","author":"Novick","year":"2001","journal-title":"Microbes Infect."},{"key":"10.1074\/jbc.M300611200_bib3","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/S0149-2918(01)80043-6","volume":"23","author":"Fung","year":"2001","journal-title":"Clin. Ther."},{"key":"10.1074\/jbc.M300611200_bib4","first-page":"2439","volume":"4","author":"Walsh","year":"2002","journal-title":"J. Clin. Microbiol."},{"key":"10.1074\/jbc.M300611200_bib5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0140-6736(01)05410-1","volume":"358","author":"Tsiodras","year":"2001","journal-title":"Lancet"},{"key":"10.1074\/jbc.M300611200_bib6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1007\/978-1-4615-4897-3_5","volume":"456","author":"Bush","year":"1998","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1074\/jbc.M300611200_bib7","series-title":"Bacterial Resistance to Antimicrobials, Mechanisms, Genetics, Medical Practice and Public Health","first-page":"123","author":"Kotra","year":"2001"},{"key":"10.1074\/jbc.M300611200_bib8","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1126\/science.8093647","volume":"259","author":"Kreiswirth","year":"1993","journal-title":"Science"},{"key":"10.1074\/jbc.M300611200_bib9","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1126\/science.1055144","volume":"291","author":"Zhang","year":"2001","journal-title":"Science"},{"key":"10.1074\/jbc.M300611200_bib10","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1126\/science.1059671","volume":"291","author":"Archer","year":"2001","journal-title":"Science"},{"key":"10.1074\/jbc.M300611200_bib11","doi-asserted-by":"crossref","first-page":"4000","DOI":"10.1093\/nar\/19.14.4000","volume":"19","author":"Wang","year":"1991","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M300611200_bib12","first-page":"1165","volume":"256","author":"Olson","year":"1981","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M300611200_bib13","doi-asserted-by":"crossref","first-page":"12712","DOI":"10.1021\/bi0114832","volume":"40","author":"Bernat","year":"2001","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M300611200_bib14","doi-asserted-by":"crossref","first-page":"4971","DOI":"10.1021\/bi992681k","volume":"39","author":"Lietz","year":"2000","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M300611200_bib15","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1042\/bj3320755","volume":"332","author":"Woodward-Graves","year":"1998","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M300611200_bib16","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1128\/AAC.43.5.1124","volume":"43","author":"Zhao","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1074\/jbc.M300611200_bib17","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","volume":"215","author":"Altschul","year":"1990","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M300611200_bib18","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0196-8858(91)90017-D","volume":"12","author":"Huang","year":"1991","journal-title":"Adv. Appl. Math."},{"key":"10.1074\/jbc.M300611200_bib19","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1042\/bst0240274","volume":"24","author":"Peitsch","year":"1996","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M300611200_bib20","series-title":"AMBER 7","author":"Case","year":"2002"},{"key":"10.1074\/jbc.M300611200_bib21","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/S0969-2126(00)00534-7","volume":"8","author":"Maveyraud","year":"2000","journal-title":"Structure"},{"key":"10.1074\/jbc.M300611200_bib22","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1063\/1.445869","volume":"79","author":"Jorgensen","year":"1983","journal-title":"J. Chem. Phys."},{"key":"10.1074\/jbc.M300611200_bib23","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1574-6968.1990.tb03785.x","volume":"70","author":"Joris","year":"1990","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1074\/jbc.M300611200_bib24","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1128\/jb.172.2.1137-1141.1990","volume":"172","author":"Zhu","year":"1990","journal-title":"J. Bacteriol."},{"key":"10.1074\/jbc.M300611200_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/AAC.42.1.1","volume":"42","author":"Massova","year":"1998","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1074\/jbc.M300611200_bib26","doi-asserted-by":"crossref","first-page":"14280","DOI":"10.1073\/pnas.241442898","volume":"98","author":"Golemi","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M300611200_bib27","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1021\/ja016736t","volume":"124","author":"Maveyraud","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M300611200_bib28","doi-asserted-by":"crossref","first-page":"7809","DOI":"10.1073\/pnas.96.14.7809","volume":"96","author":"Tien","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M300611200_bib29","doi-asserted-by":"crossref","first-page":"6862","DOI":"10.1128\/JB.183.23.6862-6868.2001","volume":"183","author":"McKinney","year":"2001","journal-title":"J. Bacteriol."},{"key":"10.1074\/jbc.M300611200_bib30","doi-asserted-by":"crossref","first-page":"2429","DOI":"10.1126\/science.291.5512.2429","volume":"291","author":"Volkman","year":"2001","journal-title":"Science"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819549456?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819549456?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M300611200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T10:56:52Z","timestamp":1639825012000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819549456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,5]]},"references-count":30,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2003,5]]}},"alternative-id":["S0021925819549456"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m300611200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2003,5]]}}}