{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T09:08:57Z","timestamp":1790327337013,"version":"4.1.0"},"reference-count":53,"publisher":"Elsevier BV","issue":"31","license":[{"start":{"date-parts":[[2003,8,1]],"date-time":"2003-08-01T00:00:00Z","timestamp":1059696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,29]],"date-time":"2020-09-29T00:00:00Z","timestamp":1601337600000},"content-version":"vor","delay-in-days":6269,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2003,8]]},"DOI":"10.1074\/jbc.m301401200","type":"journal-article","created":{"date-parts":[[2003,7,25]],"date-time":"2003-07-25T17:45:52Z","timestamp":1059155152000},"page":"29231-29239","update-policy":"https:\/\/doi.org\/10.1074\/jbc.f110.005975","source":"Crossref","is-referenced-by-count":34,"title":["Syntaxin 1A Modulates the Voltage-gated L-type Calcium Channel (Cav1.2) in a Cooperative Manner"],"prefix":"10.1016","volume":"278","author":[{"given":"Hadar","family":"Arien","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ofer","family":"Wiser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isaiah T.","family":"Arkin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hadas","family":"Leonov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daphne","family":"Atlas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M301401200_bib1","first-page":"5409","volume":"7","author":"Sollner","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.M301401200_bib2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/372055a0","volume":"372","author":"Rothman","year":"1994","journal-title":"Nature"},{"key":"10.1074\/jbc.M301401200_bib3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/26412","volume":"395","author":"Sutton","year":"1998","journal-title":"Nature"},{"key":"10.1074\/jbc.M301401200_bib4","doi-asserted-by":"crossref","first-page":"11370","DOI":"10.1074\/jbc.273.18.11370","volume":"273","author":"Poirier","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib5","doi-asserted-by":"crossref","first-page":"15458","DOI":"10.1074\/jbc.M011687200","volume":"276","author":"Lewis","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib6","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0014-5793(99)00028-9","volume":"446","author":"Margittai","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M301401200_bib7","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1002\/j.1460-2075.1995.tb06994.x","volume":"14","author":"Kutay","year":"1995","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M301401200_bib8","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1242\/jcs.115.8.1689","volume":"115","author":"Bulbarelli","year":"2002","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M301401200_bib9","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1432-1033.1997.00540.x","volume":"249","author":"Laage","year":"1997","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M301401200_bib10","doi-asserted-by":"crossref","first-page":"17481","DOI":"10.1074\/jbc.M910092199","volume":"275","author":"Laage","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib11","doi-asserted-by":"crossref","first-page":"4100","DOI":"10.1002\/j.1460-2075.1996.tb00785.x","volume":"15","author":"Wiser","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M301401200_bib12","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0306-4522(01)00083-5","volume":"104","author":"Trus","year":"2001","journal-title":"Neuroscience"},{"key":"10.1074\/jbc.M301401200_bib13","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1023\/A:1015104105262","volume":"21","author":"Atlas","year":"2001","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1074\/jbc.M301401200_bib14","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1113\/jphysiol.1995.sp021029","volume":"489","author":"Shistik","year":"1995","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.M301401200_bib15","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0014-5793(94)00938-4","volume":"352","author":"Mitterdorfer","year":"1994","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M301401200_bib16","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1126\/science.7906056","volume":"263","author":"Mastrogiacomo","year":"1994","journal-title":"Science"},{"key":"10.1074\/jbc.M301401200_bib17","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1113\/jphysiol.1996.sp021291","volume":"492","author":"Kamp","year":"1996","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.M301401200_bib18","doi-asserted-by":"crossref","first-page":"27975","DOI":"10.1074\/jbc.271.45.27975","volume":"271","author":"Gurnett","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib19","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/S0166-2236(97)01200-9","volume":"21","author":"Walker","year":"1998","journal-title":"Trends Neurosci."},{"key":"10.1074\/jbc.M301401200_bib20","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/j.1469-7793.1999.685ab.x","volume":"515","author":"Brice","year":"1999","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.M301401200_bib21","doi-asserted-by":"crossref","first-page":"13488","DOI":"10.1074\/jbc.273.22.13488","volume":"273","author":"Leveque","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib22","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1074\/jbc.274.4.2137","volume":"274","author":"Gao","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib23","doi-asserted-by":"crossref","first-page":"7614","DOI":"10.1523\/JNEUROSCI.20-20-07614.2000","volume":"20","author":"Mirotznik","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M301401200_bib24","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1523\/JNEUROSCI.21-09-02939.2001","volume":"21","author":"Jarvis","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M301401200_bib25","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0896-6273(02)00667-0","volume":"34","author":"Hibino","year":"2002","journal-title":"Neuron"},{"key":"10.1074\/jbc.M301401200_bib26","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/0896-6273(94)90417-0","volume":"13","author":"Sheng","year":"1994","journal-title":"Neuron"},{"key":"10.1074\/jbc.M301401200_bib27","doi-asserted-by":"crossref","first-page":"7363","DOI":"10.1073\/pnas.93.14.7363","volume":"93","author":"Rettig","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M301401200_bib28","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/378623a0","volume":"378","author":"Bezprozvanny","year":"1995","journal-title":"Nature"},{"key":"10.1074\/jbc.M301401200_bib29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0014-5793(97)00130-0","volume":"404","author":"Wiser","year":"1997","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M301401200_bib30","first-page":"89","volume":"6","author":"Tobi","year":"1998","journal-title":"Receptors Channels"},{"key":"10.1074\/jbc.M301401200_bib31","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1073\/pnas.96.1.248","volume":"96","author":"Wiser","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M301401200_bib32","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1749-6632.1999.tb11284.x","volume":"868","author":"Catterall","year":"1999","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1074\/jbc.M301401200_bib33","doi-asserted-by":"crossref","first-page":"3968","DOI":"10.1073\/pnas.052017299","volume":"99","author":"Wiser","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M301401200_bib34","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1046\/j.1471-4159.2001.00347.x","volume":"77","author":"Atlas","year":"2001","journal-title":"J. Neurochem."},{"key":"10.1074\/jbc.M301401200_bib35","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1107\/S0907444998003254","volume":"5","author":"Brunger","year":"1998","journal-title":"Acta Crystallogr. Sect. D Biol. Crystallogr."},{"key":"10.1074\/jbc.M301401200_bib36","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1021\/ja00214a001","volume":"110","author":"Jorgensen","year":"1998","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M301401200_bib37","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1038\/nsb0295-154","volume":"2","author":"Adams","year":"1995","journal-title":"Nat. Struct. Biol."},{"key":"10.1074\/jbc.M301401200_bib38","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1126\/science.1716787","volume":"253","author":"Singer","year":"1991","journal-title":"Science"},{"key":"10.1074\/jbc.M301401200_bib39","doi-asserted-by":"crossref","first-page":"2646","DOI":"10.1016\/S0021-9258(18)89409-1","volume":"260","author":"Frost","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib40","doi-asserted-by":"crossref","first-page":"10566","DOI":"10.1074\/jbc.270.18.10566","volume":"270","author":"Schiavo","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib41","doi-asserted-by":"crossref","first-page":"13943","DOI":"10.1073\/pnas.220389697","volume":"97","author":"Bezprozvanny","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M301401200_bib42","first-page":"72","volume":"325","author":"Frank","year":"2000","journal-title":"Ann. Med."},{"key":"10.1074\/jbc.M301401200_bib43","doi-asserted-by":"crossref","first-page":"15861","DOI":"10.1021\/bi0269411","volume":"41","author":"Bowen","year":"2002","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M301401200_bib44","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1469-7793.1998.347bk.x","volume":"510","author":"Wyatt","year":"1998","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.M301401200_bib45","doi-asserted-by":"crossref","first-page":"19348","DOI":"10.1074\/jbc.273.30.19348","volume":"273","author":"Yamaguchi","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M301401200_bib46","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/BFb0033648","volume":"139","author":"Hofmann","year":"1999","journal-title":"Rev. Physiol. Biochem. Pharmacol."},{"key":"10.1074\/jbc.M301401200_bib47","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1159\/000016320","volume":"9","author":"Striessnig","year":"1999","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1074\/jbc.M301401200_bib48","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1146\/annurev.cellbio.16.1.521","volume":"16","author":"Catterall","year":"2000","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1074\/jbc.M301401200_bib49","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0022-2836(02)00890-2","volume":"323","author":"Wang","year":"2002","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M301401200_bib50","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1021\/bi00882a012","volume":"4","author":"Gerhart","year":"1965","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M301401200_bib51","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1113\/jphysiol.1967.sp008367","volume":"193","author":"Dodge","year":"1967","journal-title":"J. Physiol. (Lond.)"},{"key":"10.1074\/jbc.M301401200_bib52","doi-asserted-by":"crossref","first-page":"13955","DOI":"10.1073\/pnas.250491397","volume":"97","author":"Stewart","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M301401200_bib53","doi-asserted-by":"crossref","first-page":"9258","DOI":"10.1074\/jbc.M210270200","volume":"278","author":"Cohen","year":"2003","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820844263?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820844263?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M301401200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T21:21:18Z","timestamp":1641417678000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820844263"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8]]},"references-count":53,"journal-issue":{"issue":"31","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["S0021925820844263"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m301401200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2003,8]]}}}