{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:05:28Z","timestamp":1791234328696,"version":"4.1.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"18","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,5]],"date-time":"2020-10-05T00:00:00Z","timestamp":1601856000000},"content-version":"vor","delay-in-days":6031,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2004,4]]},"DOI":"10.1074\/jbc.m312609200","type":"journal-article","created":{"date-parts":[[2004,4,23]],"date-time":"2004-04-23T18:58:10Z","timestamp":1082746690000},"page":"18157-18168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":101,"title":["Human Fibroblasts with Mutations in COL5A1 and COL3A1 Genes Do Not Organize Collagens and Fibronectin in the Extracellular Matrix, Down-regulate \u03b12\u03b21 Integrin, and Recruit \u03b1v\u03b23 Instead of \u03b15\u03b21 Integrin"],"prefix":"10.1016","volume":"279","author":[{"given":"Nicoletta","family":"Zoppi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Gardella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"De Paepe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"Barlati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Colombi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M312609200_bib1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s001090050215","volume":"76","author":"Aumailley","year":"1998","journal-title":"J. Mol. Med."},{"key":"10.1074\/jbc.M312609200_bib2","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0092-8674(00)81279-9","volume":"84","author":"Gumbiner","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M312609200_bib3","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1146\/annurev.cb.04.110188.001151","volume":"4","author":"McDonald","year":"1988","journal-title":"Annu. Rev. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib4","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/S0955-0674(97)80123-8","volume":"9","author":"Giancotti","year":"1997","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0955-0674(97)80124-X","volume":"9","author":"Frisch","year":"1997","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib6","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S0955-0674(99)00026-5","volume":"11","author":"Streuli","year":"1999","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib7","first-page":"793","volume":"2","author":"Geiger","year":"2001","journal-title":"Nature"},{"key":"10.1074\/jbc.M312609200_bib8","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0959-440X(05)80155-1","volume":"3","author":"Mosher","year":"1993","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1074\/jbc.M312609200_bib9","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0955-0674(99)00017-4","volume":"11","author":"Schwarzbauer","year":"1999","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jcp.1137","volume":"189","author":"Danen","year":"2001","journal-title":"J. Cell. Physiol."},{"key":"10.1074\/jbc.M312609200_bib11","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1146\/annurev.bi.64.070195.002155","volume":"64","author":"Prockop","year":"1995","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M312609200_bib12","series-title":"Connective Tissue and Its Heritable Disorders: Molecular Genetics and Medical Aspects","first-page":"103","author":"Kielty","year":"1993"},{"key":"10.1074\/jbc.M312609200_bib13","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0968-4328(00)00043-3","volume":"32","author":"Birk","year":"2001","journal-title":"Micron"},{"key":"10.1074\/jbc.M312609200_bib14","series-title":"Connective Tissue and Its Heritable Disorders: Molecular Genetics and Medical Aspects","first-page":"351","author":"Steinmann","year":"1993"},{"key":"10.1074\/jbc.M312609200_bib15","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1136\/jmg.34.5.400","volume":"34","author":"Pope","year":"1997","journal-title":"J. Med. Genet."},{"key":"10.1074\/jbc.M312609200_bib16","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1093\/hmg\/7.2.249","volume":"7","author":"Michalickova","year":"1998","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M312609200_bib17","doi-asserted-by":"crossref","first-page":"13356","DOI":"10.1074\/jbc.M011742200","volume":"276","author":"Bouma","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M312609200_bib18","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1006\/geno.1993.1074","volume":"15","author":"Ilautala","year":"1993","journal-title":"Genomics"},{"key":"10.1074\/jbc.M312609200_bib19","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1086\/302504","volume":"65","author":"Colige","year":"1999","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/jbc.M312609200_bib20","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1159\/000246984","volume":"189","author":"De Paepe","year":"1994","journal-title":"Dermatology"},{"key":"10.1074\/jbc.M312609200_bib21","doi-asserted-by":"crossref","first-page":"25533","DOI":"10.1074\/jbc.273.40.25533","volume":"273","author":"Sechler","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M312609200_bib22","series-title":"Fibronectin","first-page":"213","author":"Colvin","year":"1989"},{"key":"10.1074\/jbc.M312609200_bib23","series-title":"Fibronectin","first-page":"181","author":"Thi\u00e9ry","year":"1989"},{"key":"10.1074\/jbc.M312609200_bib24","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0945-053X(01)00160-3","volume":"20","author":"Sabatelli","year":"2001","journal-title":"Matrix Biol."},{"key":"10.1074\/jbc.M312609200_bib25","doi-asserted-by":"crossref","first-page":"14346","DOI":"10.1074\/jbc.M211997200","volume":"278","author":"Colombi","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M312609200_bib26","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1083\/jcb.121.5.1165","volume":"121","author":"Dzamba","year":"1993","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib27","doi-asserted-by":"crossref","first-page":"37377","DOI":"10.1074\/jbc.M206286200","volume":"277","author":"Velling","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M312609200_bib28","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1242\/jcs.111.18.2763","volume":"111","author":"Chernousov","year":"1998","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M312609200_bib29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(92)90115-S","volume":"69","author":"Hynes","year":"1999","journal-title":"Cell"},{"key":"10.1074\/jbc.M312609200_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-230X(08)60772-1","volume":"76","author":"Ruoslahti","year":"1999","journal-title":"Adv. Cancer Res."},{"key":"10.1074\/jbc.M312609200_bib31","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0955-0674(99)80037-4","volume":"11","author":"Schoenwaelder","year":"1999","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib32","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0955-0674(99)00067-8","volume":"12","author":"Critchley","year":"2000","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib33","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0945-053X(00)00076-7","volume":"19","author":"Heino","year":"2000","journal-title":"Matrix Biol."},{"key":"10.1074\/jbc.M312609200_bib34","first-page":"506","volume":"11","author":"Vogel","year":"2001","journal-title":"Eur. J. Dermatol."},{"key":"10.1074\/jbc.M312609200_bib35","doi-asserted-by":"crossref","first-page":"149","DOI":"10.3109\/15419069609014219","volume":"4","author":"Wu","year":"1996","journal-title":"Cell Adhes. Commun."},{"key":"10.1074\/jbc.M312609200_bib36","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/1523-1747.ep12328177","volume":"106","author":"Gailit","year":"1996","journal-title":"J. Investig. Dermatol."},{"key":"10.1074\/jbc.M312609200_bib37","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1046\/j.1523-1747.1999.00786.x","volume":"133","author":"Feng","year":"1999","journal-title":"J. Investig. Dermatol."},{"key":"10.1074\/jbc.M312609200_bib38","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1242\/jcs.110.7.861","volume":"110","author":"Greiling","year":"1997","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M312609200_bib39","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1083\/jcb.113.4.919","volume":"113","author":"Wayner","year":"1991","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib40","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1091\/mbc.12.10.3126","volume":"12","author":"Retta","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M312609200_bib41","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/0309-1651(91)90090-6","volume":"15","author":"Barlati","year":"1991","journal-title":"Cell Biol. Int. Rep."},{"key":"10.1074\/jbc.M312609200_bib42","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/cbir.1994.1004","volume":"18","author":"Moro","year":"1994","journal-title":"Cell Biol. Int."},{"key":"10.1074\/jbc.M312609200_bib43","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1006\/cbir.1998.0283","volume":"22","author":"Zoppi","year":"1998","journal-title":"Cell Biol. Int."},{"key":"10.1074\/jbc.M312609200_bib44","first-page":"547","volume":"60","author":"De Paepe","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"10.1074\/jbc.M312609200_bib45","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1006\/excr.1994.1200","volume":"213","author":"De Petro","year":"1994","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M312609200_bib46","first-page":"3142","volume":"56","author":"Hangan","year":"1996","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M312609200_bib47","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1083\/jcb.81.1.83","volume":"81","author":"Hedman","year":"1979","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib48","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0248-4900(99)80076-8","volume":"89","author":"Beauvais-Jouneau","year":"1997","journal-title":"Biol. Cell"},{"key":"10.1074\/jbc.M312609200_bib49","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1365-2133.1988.tb01745.x","volume":"118","author":"Temple","year":"1988","journal-title":"Br. J. Dermatol."},{"key":"10.1074\/jbc.M312609200_bib50","series-title":"Extracellular Matrix Genes","first-page":"251","author":"Byers","year":"1990"},{"key":"10.1074\/jbc.M312609200_bib51","doi-asserted-by":"crossref","first-page":"26794","DOI":"10.1074\/jbc.270.45.26794","volume":"270","author":"Delcommenne","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M312609200_bib52","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1083\/jcb.132.1.239","volume":"132","author":"Xu","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib53","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1083\/jcb.145.4.889","volume":"145","author":"Blaystone","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib54","doi-asserted-by":"crossref","first-page":"E75","DOI":"10.1038\/ncb0402-e75","volume":"4","author":"Yamada","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib55","doi-asserted-by":"crossref","first-page":"29380","DOI":"10.1074\/jbc.272.46.29380","volume":"14","author":"Simon","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M312609200_bib56","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1083\/jcb.143.1.241","volume":"143","author":"Wu","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M312609200_bib57","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1126\/science.1064829","volume":"294","author":"Cukierman","year":"2001","journal-title":"Science"},{"key":"10.1074\/jbc.M312609200_bib58","doi-asserted-by":"crossref","first-page":"6622","DOI":"10.1093\/emboj\/17.22.6622","volume":"17","author":"Moro","year":"1998","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M312609200_bib59","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1093\/emboj\/18.4.882","volume":"18","author":"Soldi","year":"1999","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M312609200_bib60","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1091\/mbc.4.9.953","volume":"4","author":"Meredith","year":"1993","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M312609200_bib61","doi-asserted-by":"crossref","first-page":"6161","DOI":"10.1073\/pnas.92.13.6161","volume":"92","author":"Zhang","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M312609200_bib62","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/1523-1747.ep12667776","volume":"99","author":"Oliver","year":"1992","journal-title":"J. Investig. Dermatol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819753605?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819753605?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M312609200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T12:04:53Z","timestamp":1639829093000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819753605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4]]},"references-count":62,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2004,4]]}},"alternative-id":["S0021925819753605"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m312609200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2004,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human Fibroblasts with Mutations in COL5A1 and COL3A1 Genes Do Not Organize Collagens and Fibronectin in the Extracellular Matrix, Down-regulate \u03b12\u03b21 Integrin, and Recruit \u03b1v\u03b23 Instead of \u03b15\u03b21 Integrin","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M312609200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2004 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}