{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T17:04:41Z","timestamp":1790874281114,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,3]],"date-time":"2020-11-03T00:00:00Z","timestamp":1604361600000},"content-version":"vor","delay-in-days":6091,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1074\/jbc.m313682200","type":"journal-article","created":{"date-parts":[[2004,3,5]],"date-time":"2004-03-05T22:43:17Z","timestamp":1078526597000},"page":"10476-10483","source":"Crossref","is-referenced-by-count":28,"title":["High Incidence of Thymic Epithelial Tumors in E2F2 Transgenic Mice"],"prefix":"10.1016","volume":"279","author":[{"given":"Blanca","family":"Scheijen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke","family":"Bronk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany","family":"van der Meer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daphne","family":"De Jong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren\u00e9","family":"Bernards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M313682200_bib1","doi-asserted-by":"crossref","first-page":"4684","DOI":"10.1128\/MCB.21.14.4684-4699.2001","volume":"21","author":"Ishida","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1101\/gad.949802","volume":"16","author":"Ren","year":"2002","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M313682200_bib3","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1101\/gad.864201","volume":"15","author":"Muller","year":"2001","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M313682200_bib4","doi-asserted-by":"crossref","first-page":"7594","DOI":"10.1073\/pnas.93.15.7594","volume":"93","author":"Rogers","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M313682200_bib5","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.1242\/jcs.109.10.2443","volume":"109","author":"de la Luna","year":"1996","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M313682200_bib6","first-page":"1437","volume":"11","author":"Ormondroyd","year":"1995","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M313682200_bib7","doi-asserted-by":"crossref","first-page":"42041","DOI":"10.1074\/jbc.M308105200","volume":"278","author":"de Bruin","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M313682200_bib8","doi-asserted-by":"crossref","first-page":"6289","DOI":"10.1093\/emboj\/cdg613","volume":"22","author":"Di Stefano","year":"2003","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M313682200_bib9","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1128\/MCB.18.2.753","volume":"18","author":"Lundberg","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib10","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0092-8674(00)81519-6","volume":"98","author":"Harbour","year":"1999","journal-title":"Cell"},{"key":"10.1074\/jbc.M313682200_bib11","first-page":"131","volume":"1602","author":"DeGregori","year":"2002","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M313682200_bib12","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/S0092-8674(00)81255-6","volume":"85","author":"Field","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M313682200_bib13","first-page":"829","volume":"10","author":"Zhu","year":"1999","journal-title":"Cell Growth Differ."},{"key":"10.1074\/jbc.M313682200_bib14","first-page":"91","volume":"11","author":"Garcia","year":"2000","journal-title":"Cell Growth Differ."},{"key":"10.1074\/jbc.M313682200_bib15","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S1074-7613(01)00254-0","volume":"15","author":"Murga","year":"2001","journal-title":"Immunity"},{"key":"10.1074\/jbc.M313682200_bib16","doi-asserted-by":"crossref","first-page":"8547","DOI":"10.1128\/MCB.21.24.8547-8564.2001","volume":"21","author":"Zhu","year":"2001","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib17","doi-asserted-by":"crossref","first-page":"3607","DOI":"10.1128\/MCB.23.10.3607-3622.2003","volume":"23","author":"Li","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib18","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1101\/gad.14.6.690","volume":"14","author":"Humbert","year":"2000","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M313682200_bib19","doi-asserted-by":"crossref","first-page":"2663","DOI":"10.1128\/MCB.22.8.2663-2672.2002","volume":"22","author":"Cloud","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib20","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/35106593","volume":"414","author":"Wu","year":"2001","journal-title":"Nature"},{"key":"10.1074\/jbc.M313682200_bib21","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/S0092-8674(00)81254-4","volume":"85","author":"Yamasaki","year":"1996","journal-title":"Cell"},{"key":"10.1074\/jbc.M313682200_bib22","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/nm0698-685","volume":"4","author":"Fueyo","year":"1998","journal-title":"Nat. Med."},{"key":"10.1074\/jbc.M313682200_bib23","first-page":"4722","volume":"57","author":"Hunt","year":"1997","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M313682200_bib24","first-page":"1776","volume":"62","author":"Dong","year":"2002","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M313682200_bib25","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1159\/000059708","volume":"23","author":"Elliott","year":"2002","journal-title":"Tumour Biol."},{"key":"10.1074\/jbc.M313682200_bib26","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1084\/jem.183.3.1205","volume":"183","author":"Bargou","year":"1996","journal-title":"J. Exp. Med."},{"key":"10.1074\/jbc.M313682200_bib27","first-page":"3276","volume":"62","author":"Rounbehler","year":"2002","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M313682200_bib28","doi-asserted-by":"crossref","first-page":"5054","DOI":"10.1038\/sj.onc.1203885","volume":"19","author":"Conner","year":"2000","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M313682200_bib29","doi-asserted-by":"crossref","first-page":"6408","DOI":"10.1128\/MCB.19.9.6408","volume":"19","author":"Pierce","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib30","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1038\/sj.onc.1201666","volume":"16","author":"Pierce","year":"1998","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M313682200_bib31","doi-asserted-by":"crossref","first-page":"8858","DOI":"10.1073\/pnas.95.15.8858","volume":"95","author":"Pierce","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M313682200_bib32","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/ng0498-360","volume":"18","author":"Yamasaki","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M313682200_bib33","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/S1097-2765(03)00102-3","volume":"11","author":"Baudino","year":"2003","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M313682200_bib34","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/ncb1001","volume":"5","author":"Wikonkal","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M313682200_bib35","first-page":"4223","volume":"41","author":"Chen","year":"2000","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1074\/jbc.M313682200_bib36","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/intimm\/6.1.31","volume":"6","author":"Izon","year":"1994","journal-title":"Int. Immunol."},{"key":"10.1074\/jbc.M313682200_bib37","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1002\/eji.1830140608","volume":"14","author":"Van Vliet","year":"1984","journal-title":"Eur. J. Immunol."},{"key":"10.1074\/jbc.M313682200_bib38","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/374724a0","volume":"374","author":"Alkema","year":"1995","journal-title":"Nature"},{"key":"10.1074\/jbc.M313682200_bib39","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1038\/sj.onc.1201262","volume":"15","author":"Alkema","year":"1997","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M313682200_bib40","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1038\/sj.onc.1201288","volume":"15","author":"Allen","year":"1997","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M313682200_bib41","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/0167-5699(93)90248-J","volume":"14","author":"Boyd","year":"1993","journal-title":"Immunol. Today"},{"key":"10.1074\/jbc.M313682200_bib42","doi-asserted-by":"crossref","first-page":"11822","DOI":"10.1073\/pnas.95.20.11822","volume":"95","author":"Klug","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M313682200_bib43","doi-asserted-by":"crossref","first-page":"7634","DOI":"10.1073\/pnas.93.15.7634","volume":"93","author":"Robles","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M313682200_bib44","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/S0002-9440(10)64616-0","volume":"157","author":"Rodriguez-Puebla","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1074\/jbc.M313682200_bib45","first-page":"M1","volume":"1470","author":"Muller","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M313682200_bib46","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1101\/gad.813200","volume":"14","author":"Harbour","year":"2000","journal-title":"Genes Dev."},{"key":"10.1074\/jbc.M313682200_bib47","doi-asserted-by":"crossref","first-page":"7245","DOI":"10.1073\/pnas.94.14.7245","volume":"94","author":"DeGregori","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M313682200_bib48","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1128\/MCB.16.3.1047","volume":"16","author":"Lukas","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib49","first-page":"625","volume":"11","author":"Smith","year":"2000","journal-title":"Cell Growth Differ."},{"key":"10.1074\/jbc.M313682200_bib50","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/ng891","volume":"31","author":"Lomazzi","year":"2002","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M313682200_bib51","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1126\/science.287.5457.1431","volume":"287","author":"Slack","year":"2000","journal-title":"Science"},{"key":"10.1074\/jbc.M313682200_bib52","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0925-4773(97)00083-X","volume":"66","author":"Dagnino","year":"1997","journal-title":"Mech. Dev."},{"key":"10.1074\/jbc.M313682200_bib53","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/sj.onc.1201546","volume":"16","author":"Rampalli","year":"1998","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M313682200_bib54","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/S1074-7613(02)00321-7","volume":"16","author":"Bennett","year":"2002","journal-title":"Immunity"},{"key":"10.1074\/jbc.M313682200_bib55","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/ni812","volume":"3","author":"Gill","year":"2002","journal-title":"Nat. Immunol."},{"key":"10.1074\/jbc.M313682200_bib56","doi-asserted-by":"crossref","first-page":"5157","DOI":"10.1128\/MCB.22.14.5157-5172.2002","volume":"22","author":"Rheinwald","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M313682200_bib57","doi-asserted-by":"crossref","first-page":"8148","DOI":"10.1038\/sj.onc.1205007","volume":"20","author":"Carraresi","year":"2001","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M313682200_bib58","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s004280050131","volume":"432","author":"Lee","year":"1998","journal-title":"Virchows Arch."},{"key":"10.1074\/jbc.M313682200_bib59","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/342185a0","volume":"342","author":"Spanopoulou","year":"1989","journal-title":"Nature"},{"key":"10.1074\/jbc.M313682200_bib60","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S0092-8674(88)90289-9","volume":"53","author":"Ruther","year":"1988","journal-title":"Cell"},{"key":"10.1074\/jbc.M313682200_bib61","doi-asserted-by":"crossref","first-page":"3656","DOI":"10.1128\/MCB.23.10.3656-3668.2003","volume":"23","author":"Scheijen","year":"2003","journal-title":"Mol. Cell. Biol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925817477052?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925817477052?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M313682200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T21:36:36Z","timestamp":1639690596000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925817477052"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":61,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S0021925817477052"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m313682200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}