{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T21:26:53Z","timestamp":1790371613078,"version":"4.1.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"25","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T00:00:00Z","timestamp":1601078400000},"content-version":"vor","delay-in-days":5961,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2004,6]]},"DOI":"10.1074\/jbc.m401482200","type":"journal-article","created":{"date-parts":[[2004,6,11]],"date-time":"2004-06-11T20:23:29Z","timestamp":1086985409000},"page":"26612-26618","source":"Crossref","is-referenced-by-count":26,"title":["Nanosecond Dynamics of Acetylcholinesterase Near the Active Center Gorge"],"prefix":"10.1016","volume":"279","author":[{"given":"Aileen E.","family":"Boyd","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina S.","family":"Dunlop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilly","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoran","family":"Radi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palmer","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M401482200_bib1","first-page":"103","volume":"43","author":"Rosenberry","year":"1975","journal-title":"Adv. Enzymol. Relat. Areas Mol. Biol."},{"key":"10.1074\/jbc.M401482200_bib2","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1021\/cr00081a005","volume":"253","author":"Quinn","year":"1987","journal-title":"Chem. Rev."},{"key":"10.1074\/jbc.M401482200_bib3","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1126\/science.1678899","volume":"253","author":"Sussman","year":"1991","journal-title":"Science"},{"key":"10.1074\/jbc.M401482200_bib4","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/0092-8674(95)90128-0","volume":"83","author":"Bourne","year":"1995","journal-title":"Cell"},{"key":"10.1074\/jbc.M401482200_bib5","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1107\/S0907444900010659","volume":"56","author":"Kryger","year":"2000","journal-title":"Acta Crystallogr. Sect. D"},{"key":"10.1074\/jbc.M401482200_bib6","doi-asserted-by":"crossref","first-page":"5128","DOI":"10.1073\/pnas.90.11.5128","volume":"90","author":"Ripoll","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M401482200_bib7","doi-asserted-by":"crossref","first-page":"23265","DOI":"10.1074\/jbc.272.37.23265","volume":"272","author":"Radi\u0107","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib8","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/(SICI)1097-0282(200003)53:3<265::AID-BIP6>3.0.CO;2-N","volume":"53","author":"Wlodek","year":"2000","journal-title":"Biopolymers"},{"key":"10.1074\/jbc.M401482200_bib9","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1126\/science.8122110","volume":"263","author":"Gilson","year":"1994","journal-title":"Science"},{"key":"10.1074\/jbc.M401482200_bib10","doi-asserted-by":"crossref","first-page":"9513","DOI":"10.1021\/ja971226d","volume":"119","author":"Wlodek","year":"1997","journal-title":"J. Am. Chem. Soc."},{"key":"10.1074\/jbc.M401482200_bib11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/(SICI)1097-0282(199907)50:1<35::AID-BIP4>3.0.CO;2-6","volume":"50","author":"Tara","year":"1999","journal-title":"Biopolymers"},{"key":"10.1074\/jbc.M401482200_bib12","doi-asserted-by":"crossref","first-page":"27819","DOI":"10.1016\/S0021-9258(18)46859-7","volume":"269","author":"Kronman","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib13","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0014-5793(96)00374-2","volume":"386","author":"Faerman","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M401482200_bib14","doi-asserted-by":"crossref","first-page":"9280","DOI":"10.1073\/pnas.95.16.9280","volume":"95","author":"Zhou","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M401482200_bib15","doi-asserted-by":"crossref","first-page":"041902","DOI":"10.1103\/PhysRevE.63.041902","volume":"63","author":"Shen","year":"2001","journal-title":"Phys. Rev. E Stat. Nonlin. Soft Matter Phys."},{"key":"10.1074\/jbc.M401482200_bib16","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S0006-3495(01)75736-0","volume":"81","author":"Tai","year":"2001","journal-title":"Biophys. J."},{"key":"10.1074\/jbc.M401482200_bib17","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1107\/S0907444998005277","volume":"54","author":"Ravelli","year":"1998","journal-title":"Acta Crystallogr. Sect. D"},{"key":"10.1074\/jbc.M401482200_bib18","doi-asserted-by":"crossref","first-page":"42196","DOI":"10.1074\/jbc.M106896200","volume":"276","author":"Shi","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib19","doi-asserted-by":"crossref","first-page":"43301","DOI":"10.1074\/jbc.M204391200","volume":"277","author":"Shi","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib20","doi-asserted-by":"crossref","first-page":"30905","DOI":"10.1074\/jbc.M303730200","volume":"278","author":"Shi","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib21","volume":"2","author":"Steiner","year":"1991"},{"key":"10.1074\/jbc.M401482200_bib22","doi-asserted-by":"crossref","first-page":"22401","DOI":"10.1074\/jbc.M000606200","volume":"275","author":"Boyd","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib23","doi-asserted-by":"crossref","first-page":"12074","DOI":"10.1021\/bi00096a018","volume":"32","author":"Radi\u0107","year":"1993","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M401482200_bib24","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1073\/pnas.68.2.395","volume":"68","author":"Berman","year":"1971","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M401482200_bib25","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0024-3205(86)90530-8","volume":"39","author":"De la Hoz","year":"1986","journal-title":"Life Sci."},{"key":"10.1074\/jbc.M401482200_bib26","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1002\/pro.5560050411","volume":"5","author":"Marchot","year":"1996","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.M401482200_bib27","first-page":"78","volume":"10","author":"Taylor","year":"1974","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M401482200_bib28","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0006-2952(61)90145-9","volume":"7","author":"Ellman","year":"1961","journal-title":"Biochem. Pharmacol."},{"key":"10.1074\/jbc.M401482200_bib29","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/0006-2952(86)90142-5","volume":"35","author":"Levy","year":"1986","journal-title":"Biochem. Pharmacol."},{"key":"10.1074\/jbc.M401482200_bib30","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/S0076-6879(72)26026-8","volume":"26","author":"Yguerabide","year":"1972","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M401482200_bib31","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/0926-6585(66)90333-5","volume":"112","author":"Siegel","year":"1966","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1074\/jbc.M401482200_bib32","doi-asserted-by":"crossref","first-page":"13728","DOI":"10.1021\/bi980560z","volume":"37","author":"Gangal","year":"1998","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M401482200_bib33","doi-asserted-by":"crossref","first-page":"11233","DOI":"10.1016\/S0021-9258(19)78115-0","volume":"269","author":"Radi\u0107","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib34","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1074\/jbc.274.5.2963","volume":"274","author":"Bourne","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M401482200_bib35","series-title":"Crystal Structure Analysis: A Primer","author":"Glusker","year":"1985"},{"key":"10.1074\/jbc.M401482200_bib36","doi-asserted-by":"crossref","first-page":"9031","DOI":"10.1073\/pnas.90.19.9031","volume":"90","author":"Harel","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M401482200_bib37","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/S0969-2126(01)00273-8","volume":"3","author":"Harel","year":"1995","journal-title":"Structure"},{"key":"10.1074\/jbc.M401482200_bib38","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1002\/(SICI)1097-0282(19991005)50:4<347::AID-BIP1>3.0.CO;2-R","volume":"50","author":"Tara","year":"1999","journal-title":"Biopolymers"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820856518?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820856518?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M401482200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,17]],"date-time":"2021-12-17T04:24:22Z","timestamp":1639715062000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820856518"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":38,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["S0021925820856518"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m401482200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}