{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T23:02:31Z","timestamp":1768345351456,"version":"3.49.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"32","license":[{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":5898,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2004,8]]},"DOI":"10.1074\/jbc.m405174200","type":"journal-article","created":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:13:09Z","timestamp":1086048789000},"page":"34032-34037","source":"Crossref","is-referenced-by-count":54,"title":["Impaired Platelet Activation in Familial High Density Lipoprotein Deficiency (Tangier Disease)"],"prefix":"10.1016","volume":"279","author":[{"given":"Jerzy-Roch","family":"Nofer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grazyna","family":"Herminghaus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Brodde","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eberhard","family":"Morgenstern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Rust","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Engel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udo","family":"Seedorf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerd","family":"Assmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horst","family":"Bluethmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beate E.","family":"Kehrel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M405174200_bib1","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/S0022-2275(20)31588-1","volume":"42","author":"Dean","year":"2001","journal-title":"J. Lipid Res."},{"key":"10.1074\/jbc.M405174200_bib2","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1101\/gr.184901","volume":"11","author":"Dean","year":"2001","journal-title":"Genome Res."},{"key":"10.1074\/jbc.M405174200_bib3","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/bbrc.1999.0406","volume":"257","author":"Langmann","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M405174200_bib4","doi-asserted-by":"crossref","first-page":"28634","DOI":"10.1074\/jbc.M003407200","volume":"275","author":"Bortnick","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M405174200_bib5","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/j.1460-2075.1996.tb00353.x","volume":"15","author":"Luciani","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M405174200_bib6","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.1074\/jbc.272.5.2695","volume":"272","author":"Becq","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M405174200_bib7","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1096\/fj.00-0798com","volume":"15","author":"von Eckardstein","year":"2001","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M405174200_bib8","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/11905","volume":"22","author":"Brooks-Wilson","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M405174200_bib9","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/11914","volume":"22","author":"Bodzioch","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M405174200_bib10","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/11921","volume":"22","author":"Rust","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M405174200_bib11","series-title":"The Metabolic and Molecular Bases of Inherited Diseases","first-page":"2053","author":"Assman","year":"2000"},{"key":"10.1074\/jbc.M405174200_bib12","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S1471-4914(02)02289-X","volume":"8","author":"Oram","year":"2002","journal-title":"Trends Mol. Med."},{"key":"10.1074\/jbc.M405174200_bib13","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0022-2275(20)39797-2","volume":"21","author":"Shastri","year":"1980","journal-title":"J. Lipid Res."},{"key":"10.1074\/jbc.M405174200_bib14","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/j.1365-2362.1984.tb00703.x","volume":"14","author":"Vergani","year":"1984","journal-title":"Eur. J. Clin. Investig."},{"key":"10.1074\/jbc.M405174200_bib15","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1182\/blood.V68.2.498.498","volume":"68","author":"Harmon","year":"1986","journal-title":"Blood"},{"key":"10.1074\/jbc.M405174200_bib16","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/72869","volume":"24","author":"Orso","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M405174200_bib17","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1182\/blood.V91.2.491","volume":"91","author":"Kehrel","year":"1998","journal-title":"Blood"},{"key":"10.1074\/jbc.M405174200_bib18","doi-asserted-by":"crossref","first-page":"2469","DOI":"10.1182\/blood.V96.7.2469","volume":"96","author":"Dormann","year":"2000","journal-title":"Blood"},{"key":"10.1074\/jbc.M405174200_bib19","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1182\/blood.V97.4.929","volume":"97","author":"Dormann","year":"2001","journal-title":"Blood"},{"key":"10.1074\/jbc.M405174200_bib20","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1365-2141.1996.445980.x","volume":"93","author":"Xia","year":"1996","journal-title":"Br. J. Haematol."},{"key":"10.1074\/jbc.M405174200_bib21","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1113\/jphysiol.1963.sp007185","volume":"168","author":"Born","year":"1963","journal-title":"J. Physiol."},{"key":"10.1074\/jbc.M405174200_bib22","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1083\/jcb.99.2.742","volume":"99","author":"Sleight","year":"1984","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M405174200_bib23","first-page":"12420","volume":"32","author":"McIntyre","year":"1999","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M405174200_bib24","doi-asserted-by":"crossref","first-page":"32861","DOI":"10.1074\/jbc.272.52.32861","volume":"272","author":"Nofer","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M405174200_bib25","doi-asserted-by":"crossref","first-page":"34480","DOI":"10.1074\/jbc.M103782200","volume":"276","author":"Nofer","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M405174200_bib26","first-page":"273","volume":"43","author":"Morgenstern","year":"1987","journal-title":"Eur. J. Cell Biol."},{"key":"10.1074\/jbc.M405174200_bib27","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0014-5793(00)02171-2","volume":"484","author":"Hirano","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M405174200_bib28","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0021-9150(99)00498-0","volume":"152","author":"Mott","year":"2000","journal-title":"Atherosclerosis"},{"key":"10.1074\/jbc.M405174200_bib29","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/35017029","volume":"2","author":"Hamon","year":"2000","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M405174200_bib30","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1046\/j.1365-2141.1997.5003302.x","volume":"99","author":"Dachary-Prigent","year":"1997","journal-title":"Br. J. Haematol."},{"key":"10.1074\/jbc.M405174200_bib31","doi-asserted-by":"crossref","first-page":"17049","DOI":"10.1016\/S0021-9258(18)71457-9","volume":"264","author":"Sims","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M405174200_bib32","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0049-3848(86)90288-4","volume":"42","author":"Ardlie","year":"1986","journal-title":"Thromb. Res."},{"key":"10.1074\/jbc.M405174200_bib33","doi-asserted-by":"crossref","first-page":"5242","DOI":"10.1046\/j.0014-2956.2001.02448.x","volume":"268","author":"Atkinson","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M405174200_bib34","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1172\/JCI1753","volume":"101","author":"Gayle","year":"1998","journal-title":"J. Clin. Investig."},{"key":"10.1074\/jbc.M405174200_bib35","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1055\/s-0038-1660079","volume":"54","author":"Legrand","year":"1985","journal-title":"Thromb. Haemostasis"},{"key":"10.1074\/jbc.M405174200_bib36","first-page":"1265","volume":"14","author":"Dell'Angelica","year":"2000","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M405174200_bib37","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1055\/s-0037-1616221","volume":"86","author":"Huizing","year":"2001","journal-title":"Thromb. Haemostasis"},{"key":"10.1074\/jbc.M405174200_bib38","doi-asserted-by":"crossref","first-page":"27584","DOI":"10.1074\/jbc.M103264200","volume":"276","author":"Neufeld","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M405174200_bib39","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1182\/blood.V91.7.2313","volume":"91","author":"Heijinen","year":"1998","journal-title":"Blood"},{"key":"10.1074\/jbc.M405174200_bib40","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1161\/01.ATV.11.4.1007","volume":"11","author":"Robenek","year":"1991","journal-title":"Arterioscler. Thromb. Vasc. Biol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820774727?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820774727?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M405174200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T16:09:04Z","timestamp":1639843744000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820774727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":40,"journal-issue":{"issue":"32","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["S0021925820774727"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m405174200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2004,8]]}}}