{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T11:18:42Z","timestamp":1791371922117,"version":"4.3.1"},"reference-count":46,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,7]],"date-time":"2020-11-07T00:00:00Z","timestamp":1604707200000},"content-version":"vor","delay-in-days":5758,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1074\/jbc.m408375200","type":"journal-article","created":{"date-parts":[[2004,12,17]],"date-time":"2004-12-17T01:12:35Z","timestamp":1103245955000},"page":"6580-6587","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":123,"title":["Dantrolene Stabilizes Domain Interactions within the Ryanodine Receptor"],"prefix":"10.1016","volume":"280","author":[{"given":"Shigeki","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark L.","family":"Bannister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaya P.","family":"Gangopadhyay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyo","family":"Hamada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Parness","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Ikemoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M408375200_bib1","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1152\/physrev.1996.76.2.537","volume":"76","author":"Mickelson","year":"1996","journal-title":"Physiol. Rev."},{"key":"10.1074\/jbc.M408375200_bib2","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1002\/jps.2600620619","volume":"62","author":"Ellis","year":"1973","journal-title":"J. Pharmacol. Sci."},{"key":"10.1074\/jbc.M408375200_bib3","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1085\/jgp.118.4.355","volume":"118","author":"Szentesi","year":"2001","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M408375200_bib4","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0304-3940(82)90149-5","volume":"28","author":"Gallant","year":"1992","journal-title":"Neurosci. Lett."},{"key":"10.1074\/jbc.M408375200_bib5","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/00000542-198310000-00002","volume":"59","author":"Flewellen","year":"1983","journal-title":"Anesthesiology"},{"key":"10.1074\/jbc.M408375200_bib6","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1038\/252728a0","volume":"252","author":"Hainaut","year":"1974","journal-title":"Nature"},{"key":"10.1074\/jbc.M408375200_bib7","first-page":"138","volume":"201","author":"Morgan","year":"1977","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M408375200_bib8","doi-asserted-by":"crossref","first-page":"C203","DOI":"10.1152\/ajpcell.1997.272.1.C203","volume":"272","author":"Owen","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M408375200_bib9","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1007\/BF00141551","volume":"14","author":"Lamb","year":"1993","journal-title":"J. Muscle Res. Cell Motil."},{"key":"10.1074\/jbc.M408375200_bib10","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1126\/science.959824","volume":"193","author":"Van Winkle","year":"1976","journal-title":"Science"},{"key":"10.1074\/jbc.M408375200_bib11","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1146\/annurev.pa.22.040182.002213","volume":"22","author":"Herbette","year":"1982","journal-title":"Annu. Rev. Pharmacol."},{"key":"10.1074\/jbc.M408375200_bib12","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0014-2999(90)94788-Y","volume":"178","author":"Otha","year":"1990","journal-title":"Eur. J. Pharmacol."},{"key":"10.1074\/jbc.M408375200_bib13","doi-asserted-by":"crossref","first-page":"26965","DOI":"10.1074\/jbc.272.43.26965","volume":"272","author":"Fruen","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib14","doi-asserted-by":"crossref","first-page":"13810","DOI":"10.1074\/jbc.M006104200","volume":"276","author":"Zhao","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib15","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1042\/bj3260847","volume":"326","author":"Palnitkar","year":"1997","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M408375200_bib16","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1097\/00000542-199606000-00013","volume":"84","author":"Nelson","year":"1996","journal-title":"Anesthesiology"},{"key":"10.1074\/jbc.M408375200_bib17","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/BF03015252","volume":"31","author":"Britt","year":"1984","journal-title":"Can. Anaesth. Soc. J."},{"key":"10.1074\/jbc.M408375200_bib18","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0014-5793(83)80739-X","volume":"161","author":"Ohnishi","year":"1983","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M408375200_bib19","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S1050-1738(02)00163-9","volume":"12","author":"Dirksen","year":"2002","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1074\/jbc.M408375200_bib20","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0143-4160(02)00138-0","volume":"32","author":"Galli","year":"2002","journal-title":"Cell Calcium"},{"key":"10.1074\/jbc.M408375200_bib21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0960-8966(02)00218-3","volume":"13","author":"Davis","year":"2003","journal-title":"Neuromuscul. Disord."},{"key":"10.1074\/jbc.M408375200_bib22","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/hmg\/ddg121","volume":"12","author":"Monnier","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M408375200_bib23","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1093\/hmg\/ddg032","volume":"12","author":"Zorzato","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M408375200_bib24","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1373\/49.5.761","volume":"49","author":"Tammaro","year":"2003","journal-title":"Clin. Chem."},{"key":"10.1074\/jbc.M408375200_bib25","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1085\/jgp.200308791","volume":"121","author":"Avila","year":"2003","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M408375200_bib26","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1042\/BJ20040580","volume":"382","author":"Du","year":"2004","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M408375200_bib27","doi-asserted-by":"crossref","first-page":"25722","DOI":"10.1074\/jbc.M302165200","volume":"278","author":"Yang","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib28","doi-asserted-by":"crossref","first-page":"11618","DOI":"10.1074\/jbc.275.16.11618","volume":"275","author":"Yamamoto","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib29","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1021\/bi015581z","volume":"41","author":"Yamamoto","year":"2002","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M408375200_bib30","doi-asserted-by":"crossref","first-page":"671","DOI":"10.2741\/ikemoto","volume":"7","author":"Ikemoto","year":"2002","journal-title":"Front. Biosci."},{"key":"10.1074\/jbc.M408375200_bib31","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1042\/bj20040112","volume":"380","author":"Kobayashi","year":"2004","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M408375200_bib32","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1021\/jm9805079","volume":"42","author":"Palnitkar","year":"1999","journal-title":"J. Med. Chem."},{"key":"10.1074\/jbc.M408375200_bib33","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1021\/bi001502s","volume":"40","author":"Paul-Pletzer","year":"2001","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M408375200_bib34","doi-asserted-by":"crossref","first-page":"34918","DOI":"10.1074\/jbc.M205487200","volume":"277","author":"Paul-Pletzer","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib35","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/0076-6879(88)57096-9","volume":"157","author":"Ikemoto","year":"1988","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M408375200_bib36","doi-asserted-by":"crossref","first-page":"3288","DOI":"10.1021\/bi00127a034","volume":"31","author":"Kang","year":"1992","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M408375200_bib37","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/0076-6879(88)57098-2","volume":"157","author":"Inui","year":"1988","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M408375200_bib38","doi-asserted-by":"crossref","first-page":"28696","DOI":"10.1074\/jbc.270.48.28696","volume":"270","author":"El-Hayek","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib39","doi-asserted-by":"crossref","first-page":"22642","DOI":"10.1016\/S0021-9258(18)41576-1","volume":"268","author":"Chen","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib40","doi-asserted-by":"crossref","first-page":"25051","DOI":"10.1074\/jbc.272.40.25051","volume":"272","author":"Wu","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib41","doi-asserted-by":"crossref","first-page":"C207","DOI":"10.1152\/ajpcell.2001.281.1.C207","volume":"281","author":"Lamb","year":"2001","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M408375200_bib42","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1085\/jgp.119.1.15","volume":"116","author":"Shtifman","year":"2002","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M408375200_bib43","doi-asserted-by":"crossref","first-page":"18465","DOI":"10.1074\/jbc.270.31.18465","volume":"270","author":"Parness","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408375200_bib44","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1146\/annurev.ph.56.030194.002413","volume":"56","author":"Meissner","year":"1994","journal-title":"Annu. Rev. Physiol."},{"key":"10.1074\/jbc.M408375200_bib45","doi-asserted-by":"crossref","first-page":"C358","DOI":"10.1152\/ajpcell.1989.256.2.C358","volume":"256","author":"Ohta","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M408375200_bib46","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1111\/j.1365-2044.2004.03658.x","volume":"59","author":"Krause","year":"2004","journal-title":"Anaesthesia"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819627699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819627699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M408375200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,11]],"date-time":"2023-04-11T16:51:01Z","timestamp":1681231861000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819627699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":46,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0021925819627699"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m408375200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dantrolene Stabilizes Domain Interactions within the Ryanodine Receptor","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M408375200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2005 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}