{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T13:27:21Z","timestamp":1770902841710,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","issue":"52","license":[{"start":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T00:00:00Z","timestamp":1101859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T00:00:00Z","timestamp":1601596800000},"content-version":"vor","delay-in-days":5784,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2004,12]]},"DOI":"10.1074\/jbc.m408946200","type":"journal-article","created":{"date-parts":[[2004,10,16]],"date-time":"2004-10-16T00:12:39Z","timestamp":1097885559000},"page":"54173-54184","source":"Crossref","is-referenced-by-count":55,"title":["Conversion of Arginine into Ornithine by Advanced Glycation in Senescent Human Collagen and Lens Crystallins"],"prefix":"10.1016","volume":"279","author":[{"given":"David R.","family":"Sell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent M.","family":"Monnier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M408946200_bib1","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/scientificamerican0587-90","volume":"256","author":"Cerami","year":"1987","journal-title":"Sci. Am."},{"key":"10.1074\/jbc.M408946200_bib2","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0047-6374(01)00225-1","volume":"122","author":"Bailey","year":"2001","journal-title":"Mech. Ageing Dev."},{"key":"10.1074\/jbc.M408946200_bib3","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/s001250051591","volume":"44","author":"Singh","year":"2001","journal-title":"Diabetologia"},{"key":"10.1074\/jbc.M408946200_bib4","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1749-6632.2002.tb02107.x","volume":"959","author":"Baynes","year":"2002","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1074\/jbc.M408946200_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2003.08.014","volume":"419","author":"Monnier","year":"2003","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M408946200_bib6","first-page":"232","volume":"70","author":"Vlassara","year":"2003","journal-title":"Mt. Sinai J. Med."},{"key":"10.1074\/jbc.M408946200_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2337\/diabetes.48.1.1","volume":"48","author":"Baynes","year":"1999","journal-title":"Diabetes"},{"key":"10.1074\/jbc.M408946200_bib8","first-page":"1013","volume":"44","author":"Thornalley","year":"1998","journal-title":"Cell. Mol. Biol."},{"key":"10.1074\/jbc.M408946200_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj3640001","volume":"364","author":"Ahmed","year":"2002","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M408946200_bib10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/abbi.1997.0195","volume":"344","author":"Shipanova","year":"1997","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M408946200_bib11","doi-asserted-by":"crossref","first-page":"11649","DOI":"10.1016\/S0021-9258(18)99006-X","volume":"266","author":"Grandhee","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408946200_bib12","doi-asserted-by":"crossref","first-page":"24907","DOI":"10.1074\/jbc.M202681200","volume":"277","author":"Biemel","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408946200_bib13","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1016\/S0968-0896(99)00212-6","volume":"7","author":"Lederer","year":"1999","journal-title":"Bioorg. Med. Chem."},{"key":"10.1074\/jbc.M408946200_bib14","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/1521-3803(20010601)45:3<210::AID-FOOD210>3.0.CO;2-L","volume":"45","author":"Biemel","year":"2001","journal-title":"Nahrung"},{"key":"10.1074\/jbc.M408946200_bib15","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/bj3360001","volume":"336","author":"Wu","year":"1998","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M408946200_bib16","series-title":"Lehninger Principles of Biochemistry","author":"Nelson","year":"2004"},{"key":"10.1074\/jbc.M408946200_bib17","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1177\/002215540305100905","volume":"51","author":"Yu","year":"2003","journal-title":"J. Histochem. Cytochem."},{"key":"10.1074\/jbc.M408946200_bib18","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1042\/bj3301241","volume":"330","author":"Paul","year":"1998","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M408946200_bib19","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0003-2670(92)85435-9","volume":"263","author":"McLellan","year":"1992","journal-title":"Anal. Chim. Acta"},{"key":"10.1074\/jbc.M408946200_bib20","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1007\/BF02374476","volume":"36","author":"Sell","year":"1993","journal-title":"Diabetologia"},{"key":"10.1074\/jbc.M408946200_bib21","first-page":"629","volume":"4","author":"Pirie","year":"1965","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1074\/jbc.M408946200_bib22","doi-asserted-by":"crossref","first-page":"10257","DOI":"10.1073\/pnas.88.22.10257","volume":"88","author":"Nagaraj","year":"1991","journal-title":"Proc. Natl. Acad. Sci U. S. A."},{"key":"10.1074\/jbc.M408946200_bib23","doi-asserted-by":"crossref","first-page":"41638","DOI":"10.1074\/jbc.M103557200","volume":"45","author":"Glomb","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408946200_bib24","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0021-9258(18)71178-2","volume":"211","author":"Moore","year":"1954","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408946200_bib25","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0076-6879(83)91052-2","volume":"91","author":"Jentoft","year":"1983","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M408946200_bib26","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1093\/gerona\/58.6.B508","volume":"58A","author":"Sell","year":"2003","journal-title":"J. Gerontol. Biol. Sci."},{"key":"10.1074\/jbc.M408946200_bib27","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0021-9673(99)00685-8","volume":"855","author":"Chaimbault","year":"1999","journal-title":"J. Chromatogr. A"},{"key":"10.1074\/jbc.M408946200_bib28","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1096\/fasebj.14.1.145","volume":"14","author":"Sell","year":"2000","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M408946200_bib29","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1167\/iovs.03-0573","volume":"44","author":"Ahmed","year":"2003","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1074\/jbc.M408946200_bib30","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/newbio231118a0","volume":"231","author":"Sletten","year":"1971","journal-title":"Nat. New Biol."},{"key":"10.1074\/jbc.M408946200_bib31","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/eci.1971.1.4.281","volume":"1","author":"Aakesson","year":"1971","journal-title":"Eur. J. Clin. Invest."},{"key":"10.1074\/jbc.M408946200_bib32","doi-asserted-by":"crossref","first-page":"39027","DOI":"10.1074\/jbc.M006700200","volume":"275","author":"Verzijl","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408946200_bib33","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1084\/jem.158.5.1739","volume":"158","author":"Brownlee","year":"1983","journal-title":"J. Exp. Med."},{"key":"10.1074\/jbc.M408946200_bib34","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1016\/S0531-5565(01)00140-1","volume":"36","author":"Lindner","year":"2001","journal-title":"Exp. Gerontol."},{"key":"10.1074\/jbc.M408946200_bib35","unstructured":", Thornalley, P. J. (2005) in Proceedings of the Eighth International Symposium on the Maillard Reaction, Charleston, SC, August 28 to September 1, 2004, in press"},{"key":"10.1074\/jbc.M408946200_bib36","doi-asserted-by":"crossref","first-page":"12043","DOI":"10.1073\/pnas.89.24.12043","volume":"89","author":"Vlassara","year":"1992","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1074\/jbc.M408946200_bib37","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1023\/B:REMD.0000032406.84813.f6","volume":"5","author":"Vlassara","year":"2004","journal-title":"Rev. Endocr. Metab. Disord."},{"key":"10.1074\/jbc.M408946200_bib38","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1432-0436.1991.tb00870.x","volume":"46","author":"Buono","year":"1991","journal-title":"Differentiation"},{"key":"10.1074\/jbc.M408946200_bib39","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1242\/jcs.101.4.859","volume":"101","author":"Ramachandrula","year":"1992","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M408946200_bib40","doi-asserted-by":"crossref","first-page":"10000","DOI":"10.1128\/JVI.75.20.10000-10004.2001","volume":"75","author":"Boonyakiat","year":"2001","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M408946200_bib41","doi-asserted-by":"crossref","first-page":"9725","DOI":"10.1016\/S0021-9258(18)98408-5","volume":"268","author":"Cherny","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408946200_bib42","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1167\/iovs.03-0995","volume":"45","author":"Liu","year":"2004","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1074\/jbc.M408946200_bib43","doi-asserted-by":"crossref","first-page":"20796","DOI":"10.1074\/jbc.274.30.20796","volume":"274","author":"Tessier","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M408946200_bib44","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1006\/abio.2001.4992","volume":"290","author":"Wilker","year":"2001","journal-title":"Anal. Biochem."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819631753?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925819631753?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M408946200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T23:56:33Z","timestamp":1639698993000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925819631753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12]]},"references-count":44,"journal-issue":{"issue":"52","published-print":{"date-parts":[[2004,12]]}},"alternative-id":["S0021925819631753"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m408946200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2004,12]]}}}