{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:54:35Z","timestamp":1791338075197,"version":"4.3.1"},"reference-count":56,"publisher":"Elsevier BV","issue":"18","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T00:00:00Z","timestamp":1603152000000},"content-version":"vor","delay-in-days":5651,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1074\/jbc.m411681200","type":"journal-article","created":{"date-parts":[[2005,3,4]],"date-time":"2005-03-04T20:12:56Z","timestamp":1109967176000},"page":"17841-17847","source":"Crossref","is-referenced-by-count":198,"title":["The Interaction of LEDGF\/p75 with Integrase Is Lentivirus-specific and Promotes DNA Binding"],"prefix":"10.1016","volume":"280","author":[{"given":"Katrien","family":"Busschots","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Vercammen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phane","family":"Emiliani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Benarous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Engelborghs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frauke","family":"Christ","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeger","family":"Debyser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M411681200_bib1","series-title":"Retroviruses","first-page":"1","author":"Coffin","year":"1997"},{"key":"10.1074\/jbc.M411681200_bib2","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1128\/jvi.68.1.510-516.1994","volume":"68","author":"Lewis","year":"1994","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib3","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1002\/j.1460-2075.1993.tb05858.x","volume":"12","author":"Roe","year":"1993","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M411681200_bib4","first-page":"19","volume":"157","author":"Brown","year":"1997","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1074\/jbc.M411681200_bib5","doi-asserted-by":"crossref","first-page":"23213","DOI":"10.1074\/jbc.R100027200","volume":"276","author":"Craigie","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0166-3542(97)00046-6","volume":"36","author":"Asante-Appiah","year":"1997","journal-title":"Antiviral Res."},{"key":"10.1074\/jbc.M411681200_bib7","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0065-3527(08)60306-1","volume":"52","author":"Asante-Appiah","year":"1999","journal-title":"Adv. Virus Res."},{"key":"10.1074\/jbc.M411681200_bib8","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1002\/j.1460-2075.1993.tb05996.x","volume":"12","author":"Engelman","year":"1993","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M411681200_bib9","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1128\/jvi.68.4.2215-2223.1994","volume":"68","author":"Bushman","year":"1994","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib10","doi-asserted-by":"crossref","first-page":"6361","DOI":"10.1128\/jvi.66.11.6361-6369.1992","volume":"66","author":"Engelman","year":"1992","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib11","doi-asserted-by":"crossref","first-page":"7712","DOI":"10.1074\/jbc.271.13.7712","volume":"271","author":"Jenkins","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib12","doi-asserted-by":"crossref","first-page":"38045","DOI":"10.1074\/jbc.M205842200","volume":"277","author":"Vercammen","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib13","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1074\/jbc.M209278200","volume":"278","author":"Cherepanov","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib14","doi-asserted-by":"crossref","first-page":"6667","DOI":"10.1021\/bi972949c","volume":"37","author":"Heuer","year":"1998","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M411681200_bib15","first-page":"1389","volume":"14","author":"Cherepanov","year":"2000","journal-title":"FASEB J."},{"key":"10.1074\/jbc.M411681200_bib16","doi-asserted-by":"crossref","first-page":"33528","DOI":"10.1074\/jbc.M303594200","volume":"278","author":"Maertens","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib17","doi-asserted-by":"crossref","first-page":"5370","DOI":"10.1002\/j.1460-2075.1996.tb00921.x","volume":"15","author":"Wang","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M411681200_bib18","doi-asserted-by":"crossref","first-page":"25031","DOI":"10.1016\/S0021-9258(17)31494-1","volume":"269","author":"Pruss","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib19","doi-asserted-by":"crossref","first-page":"4704","DOI":"10.1002\/j.1460-2075.1994.tb06794.x","volume":"13","author":"Muller","year":"1994","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M411681200_bib20","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S0960-9822(95)00074-1","volume":"5","author":"Miller","year":"1995","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M411681200_bib21","doi-asserted-by":"crossref","first-page":"2002","DOI":"10.1126\/science.7801128","volume":"266","author":"Kalpana","year":"1994","journal-title":"Science"},{"key":"10.1074\/jbc.M411681200_bib22","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/S0092-8674(00)81888-7","volume":"88","author":"Farnet","year":"1997","journal-title":"Cell"},{"key":"10.1074\/jbc.M411681200_bib23","doi-asserted-by":"crossref","first-page":"12507","DOI":"10.1128\/JVI.77.23.12507-12522.2003","volume":"77","author":"Violot","year":"2003","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib24","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1073\/pnas.95.4.1528","volume":"95","author":"Lee","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M411681200_bib25","doi-asserted-by":"crossref","first-page":"6723","DOI":"10.1093\/emboj\/17.22.6723","volume":"17","author":"Ge","year":"1998","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M411681200_bib26","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/S1568-9972(03)00063-6","volume":"2","author":"Ganapathy","year":"2003","journal-title":"Autoimmun. Rev."},{"key":"10.1074\/jbc.M411681200_bib27","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1006\/bbrc.1999.1979","volume":"267","author":"Singh","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M411681200_bib28","doi-asserted-by":"crossref","first-page":"48899","DOI":"10.1074\/jbc.M100733200","volume":"276","author":"Fatma","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib29","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1006\/bbrc.2001.4887","volume":"283","author":"Singh","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M411681200_bib30","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0378-1119(99)00506-5","volume":"242","author":"Singh","year":"2000","journal-title":"Gene (Amst.)"},{"key":"10.1074\/jbc.M411681200_bib31","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/S1097-2765(00)80290-7","volume":"2","author":"Ge","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M411681200_bib32","doi-asserted-by":"crossref","first-page":"4841","DOI":"10.1128\/JVI.72.6.4841-4848.1998","volume":"72","author":"Lutzke","year":"1998","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib33","doi-asserted-by":"crossref","first-page":"3176","DOI":"10.1128\/JVI.73.4.3176-3183.1999","volume":"73","author":"van den Ent","year":"1999","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib34","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1128\/jvi.68.3.1468-1474.1994","volume":"68","author":"Vink","year":"1994","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib35","doi-asserted-by":"crossref","first-page":"6482","DOI":"10.1128\/JVI.77.11.6482-6492.2003","volume":"77","author":"Chiu","year":"2003","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib36","doi-asserted-by":"crossref","first-page":"14710","DOI":"10.1074\/jbc.M007754200","volume":"276","author":"Wang","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib37","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1016\/S0021-9258(18)54098-9","volume":"268","author":"Jonsson","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib38","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0042-6822(03)00559-2","volume":"316","author":"Villanueva","year":"2003","journal-title":"Virology"},{"key":"10.1074\/jbc.M411681200_bib39","doi-asserted-by":"crossref","first-page":"5082","DOI":"10.1021\/bi9821925","volume":"38","author":"Van Craenenbroeck","year":"1999","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M411681200_bib40","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/(SICI)1099-1352(200003\/04)13:2<93::AID-JMR492>3.0.CO;2-6","volume":"13","author":"Van Craenenbroeck","year":"2000","journal-title":"J. Mol. Recognit."},{"key":"10.1074\/jbc.M411681200_bib41","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1515\/BC.2001.043","volume":"382","author":"Van Craenenbroeck","year":"2001","journal-title":"Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib42","series-title":"Molecular Cloning: A Laboratory Manual","first-page":"11.23","author":"Sambrook","year":"1989"},{"key":"10.1074\/jbc.M411681200_bib43","doi-asserted-by":"crossref","first-page":"9524","DOI":"10.1128\/JVI.78.17.9524-9537.2004","volume":"78","author":"Llano","year":"2004","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib44","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1006\/excr.2000.5016","volume":"260","author":"Depienne","year":"2000","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M411681200_bib45","doi-asserted-by":"crossref","first-page":"18102","DOI":"10.1074\/jbc.M009029200","volume":"276","author":"Depienne","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib46","doi-asserted-by":"crossref","first-page":"9825","DOI":"10.1073\/pnas.94.18.9825","volume":"94","author":"Gallay","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M411681200_bib47","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/365666a0","volume":"365","author":"Bukrinsky","year":"1993","journal-title":"Nature"},{"key":"10.1074\/jbc.M411681200_bib48","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1128\/jvi.70.2.1027-1032.1996","volume":"70","author":"Gallay","year":"1996","journal-title":"J. Virol."},{"key":"10.1074\/jbc.M411681200_bib49","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0092-8674(00)80828-4","volume":"101","author":"Zennou","year":"2000","journal-title":"Cell"},{"key":"10.1074\/jbc.M411681200_bib50","doi-asserted-by":"crossref","first-page":"33421","DOI":"10.1074\/jbc.M404700200","volume":"279","author":"Maertens","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M411681200_bib51","doi-asserted-by":"crossref","first-page":"4401","DOI":"10.1242\/jcs.00747","volume":"116","author":"Devroe","year":"2003","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M411681200_bib52","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0092-8674(03)00760-8","volume":"115","author":"Bushman","year":"2003","journal-title":"Cell"},{"key":"10.1074\/jbc.M411681200_bib53","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1126\/science.1083413","volume":"300","author":"Wu","year":"2003","journal-title":"Science"},{"key":"10.1074\/jbc.M411681200_bib54","doi-asserted-by":"crossref","first-page":"E234","DOI":"10.1371\/journal.pbio.0020234","volume":"2","author":"Mitchell","year":"2004","journal-title":"PLoS Biol."},{"key":"10.1074\/jbc.M411681200_bib55","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s004410100398","volume":"305","author":"Nishizawa","year":"2001","journal-title":"Cell Tissue Res."},{"key":"10.1074\/jbc.M411681200_bib56","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0092-8674(02)00864-4","volume":"110","author":"Schroder","year":"2002","journal-title":"Cell"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192582065726X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192582065726X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M411681200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,18]],"date-time":"2021-06-18T23:18:37Z","timestamp":1624058317000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002192582065726X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":56,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S002192582065726X"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m411681200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}