{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T23:27:47Z","timestamp":1791156467066,"version":"4.1.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2005,2,1]],"date-time":"2005-02-01T00:00:00Z","timestamp":1107216000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,24]],"date-time":"2020-09-24T00:00:00Z","timestamp":1600905600000},"content-version":"vor","delay-in-days":5714,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2005,2]]},"DOI":"10.1074\/jbc.m412711200","type":"journal-article","created":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T01:12:44Z","timestamp":1101863564000},"page":"4367-4373","source":"Crossref","is-referenced-by-count":89,"title":["AMP-activated Protein Kinase Mediates Phenobarbital Induction of CYP2B Gene Expression in Hepatocytes and a Newly Derived Human Hepatoma Cell Line"],"prefix":"10.1016","volume":"280","author":[{"given":"Franck","family":"Rencurel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alasdair","family":"Stenhouse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon A.","family":"Hawley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Friedberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Grahame","family":"Hardie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Calum","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Roland","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M412711200_bib1","doi-asserted-by":"crossref","first-page":"13469","DOI":"10.1016\/S0021-9258(18)92717-1","volume":"266","author":"Porter","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M412711200_bib2","doi-asserted-by":"crossref","first-page":"37739","DOI":"10.1074\/jbc.R100033200","volume":"276","author":"Xie","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M412711200_bib3","first-page":"427","volume":"60","author":"Goodwin","year":"2001","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M412711200_bib4","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1124\/mol.58.6.1441","volume":"58","author":"Pascussi","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M412711200_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.pharmtox.43.100901.135754","volume":"43","author":"Conney","year":"2003","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1074\/jbc.M412711200_bib6","first-page":"363","volume":"51","author":"Frueh","year":"1997","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M412711200_bib7","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1042\/bj2810577","volume":"281","author":"Waxman","year":"1992","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M412711200_bib8","doi-asserted-by":"crossref","first-page":"5652","DOI":"10.1128\/MCB.18.10.5652","volume":"18","author":"Honkakoski","year":"1998","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M412711200_bib9","first-page":"1544","volume":"14","author":"Baes","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M412711200_bib10","doi-asserted-by":"crossref","first-page":"6043","DOI":"10.1074\/jbc.274.10.6043","volume":"274","author":"Sueyoshi","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M412711200_bib11","doi-asserted-by":"crossref","first-page":"6318","DOI":"10.1128\/MCB.19.9.6318","volume":"19","author":"Kawamoto","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M412711200_bib12","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1042\/bj3300889","volume":"330","author":"Honkakoski","year":"1998","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M412711200_bib13","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1006\/bbrc.1996.1777","volume":"229","author":"Yoshida","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M412711200_bib14","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1006\/abbi.1993.1289","volume":"303","author":"Blouin","year":"1993","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M412711200_bib15","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1124\/dmd.30.8.918","volume":"30","author":"Xiong","year":"2002","journal-title":"Drug Metab. Dispos."},{"key":"10.1074\/jbc.M412711200_bib16","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/abbi.1996.9785","volume":"337","author":"Zangar","year":"1997","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1074\/jbc.M412711200_bib17","first-page":"E1","volume":"277","author":"Winder","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M412711200_bib18","doi-asserted-by":"crossref","first-page":"896","DOI":"10.2337\/diabetes.49.6.896","volume":"49","author":"Lochhead","year":"2000","journal-title":"Diabetes"},{"key":"10.1074\/jbc.M412711200_bib19","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1042\/bst0310220","volume":"31","author":"Ferre","year":"2003","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M412711200_bib20","doi-asserted-by":"crossref","first-page":"6701","DOI":"10.1128\/MCB.20.18.6704-6711.2000","volume":"20","author":"Woods","year":"2000","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M412711200_bib21","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1042\/bj2810359","volume":"281","author":"Forrester","year":"1992","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M412711200_bib22","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0014-5793(96)01209-4","volume":"397","author":"Woods","year":"1996","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M412711200_bib23","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.2337\/diabetes.51.8.2420","volume":"51","author":"Hawley","year":"2002","journal-title":"Diabetes"},{"key":"10.1074\/jbc.M412711200_bib24","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1046\/j.1365-313X.1999.00532.x","volume":"19","author":"Sugden","year":"1999","journal-title":"Plant J."},{"key":"10.1074\/jbc.M412711200_bib25","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1083\/jcb.43.3.506","volume":"43","author":"Berry","year":"1969","journal-title":"J. Cell. Biol."},{"key":"10.1074\/jbc.M412711200_bib26","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1432-0436.1992.tb00482.x","volume":"50","author":"Armbruster","year":"1992","journal-title":"Differentiation"},{"key":"10.1074\/jbc.M412711200_bib27","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0092-8674(88)90051-7","volume":"55","author":"Thorens","year":"1988","journal-title":"Cell"},{"key":"10.1074\/jbc.M412711200_bib28","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1126\/science.161.3847.1253","volume":"161","author":"Maenpaa","year":"1968","journal-title":"Science"},{"key":"10.1074\/jbc.M412711200_bib29","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1046\/j.1432-1327.2001.02011.x","volume":"268","author":"Gomez-Lechon","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M412711200_bib30","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M412711200_bib31","first-page":"63","volume":"99","author":"Hardie","year":"2000","journal-title":"Methods Mol. Biol."},{"key":"10.1074\/jbc.M412711200_bib32","doi-asserted-by":"crossref","first-page":"6107","DOI":"10.1016\/S0021-9258(18)88943-8","volume":"260","author":"Sabina","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M412711200_bib33","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1432-1033.1995.tb20498.x","volume":"229","author":"Corton","year":"1995","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M412711200_bib34","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1006\/bbrc.1994.1627","volume":"200","author":"Sullivan","year":"1994","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M412711200_bib35","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.2337\/diab.40.10.1259","volume":"10","author":"Vincent","year":"1991","journal-title":"Diabetes"},{"key":"10.1074\/jbc.M412711200_bib36","first-page":"R936","volume":"284","author":"Longnus","year":"2003","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M412711200_bib37","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0928-0987(01)00135-X","volume":"13","author":"LeCluyse","year":"2001","journal-title":"Eur. J. Pharmacol. Sci."},{"key":"10.1074\/jbc.M412711200_bib38","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0168-8278(97)80499-0","volume":"26","author":"Guillouzo","year":"1997","journal-title":"J. Hepatol."},{"key":"10.1074\/jbc.M412711200_bib39","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0014-4827(05)80086-2","volume":"200","author":"Antoine","year":"1992","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M412711200_bib40","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1042\/bj3140903","volume":"314","author":"Rencurel","year":"1996","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M412711200_bib41","first-page":"4204","volume":"18","author":"Grobholz","year":"1993","journal-title":"Cancer Res."},{"key":"10.1074\/jbc.M412711200_bib42","doi-asserted-by":"crossref","first-page":"14146","DOI":"10.1074\/jbc.M212482200","volume":"278","author":"Wang","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M412711200_bib43","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1006\/bbrc.1995.2712","volume":"216","author":"Baffet","year":"1995","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M412711200_bib44","first-page":"1122","volume":"282","author":"Sidhu","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M412711200_bib45","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1046\/j.1432-1327.2000.01083.x","volume":"267","author":"Marc","year":"2000","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M412711200_bib46","first-page":"1270","volume":"290","author":"Galisteo","year":"1999","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M412711200_bib47","first-page":"195","author":"Karvonen","year":"1987","journal-title":"Diabetes Res."},{"key":"10.1074\/jbc.M412711200_bib48","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1093\/carcin\/21.11.2041","volume":"21","author":"Hodges","year":"2000","journal-title":"Carcinogenesis"},{"key":"10.1074\/jbc.M412711200_bib49","doi-asserted-by":"crossref","first-page":"14767","DOI":"10.1074\/jbc.273.24.14767","volume":"273","author":"Foretz","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M412711200_bib50","doi-asserted-by":"crossref","first-page":"25226","DOI":"10.1074\/jbc.M202489200","volume":"277","author":"Fryer","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M412711200_bib51","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1124\/dmd.31.4.439","volume":"31","author":"Sahi","year":"2003","journal-title":"Drug Metab. Dispos."},{"key":"10.1074\/jbc.M412711200_bib52","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/S0006-2952(01)00764-X","volume":"62","author":"Davies","year":"2001","journal-title":"Biochem. Pharmacol."},{"key":"10.1074\/jbc.M412711200_bib53","doi-asserted-by":"crossref","first-page":"7931","DOI":"10.1128\/MCB.24.18.7931-7940.2004","volume":"24","author":"Kodama","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1074\/jbc.M412711200_bib54","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1038\/sj.ijo.0802629","volume":"28","author":"Schrauwen","year":"2004","journal-title":"Int. J. Obes. Relat. Metab. Disord."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820760783?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820760783?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M412711200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T16:03:04Z","timestamp":1639843384000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820760783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,2]]}},"alternative-id":["S0021925820760783"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m412711200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2005,2]]}}}