{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:13:54Z","timestamp":1792646034914,"version":"4.5.0"},"reference-count":113,"publisher":"Elsevier BV","issue":"26","license":[{"start":{"date-parts":[[2005,7,1]],"date-time":"2005-07-01T00:00:00Z","timestamp":1120176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,10]],"date-time":"2020-10-10T00:00:00Z","timestamp":1602288000000},"content-version":"vor","delay-in-days":5580,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2005,7]]},"DOI":"10.1074\/jbc.m414090200","type":"journal-article","created":{"date-parts":[[2005,5,4]],"date-time":"2005-05-04T20:12:46Z","timestamp":1115237566000},"page":"25048-25059","source":"Crossref","is-referenced-by-count":168,"title":["Functional Selectivity of G Protein Signaling by Agonist Peptides and Thrombin for the Protease-activated Receptor-1"],"prefix":"10.1016","volume":"280","author":[{"given":"Joseph N.","family":"McLaughlin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lixin","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Holinstat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua D.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuele","family":"DiBenedetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi E.","family":"Hamm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M414090200_bib1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1124\/mol.54.1.94","volume":"54","author":"Berg","year":"1998","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1124\/jpet.102.042184","volume":"304","author":"Kurrasch-Orbaugh","year":"2003","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M414090200_bib3","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1124\/mol.63.1.36","volume":"63","author":"Ebersole","year":"2003","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib4","doi-asserted-by":"crossref","first-page":"24433","DOI":"10.1074\/jbc.C100162200","volume":"276","author":"Ghanouni","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib5","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1124\/jpet.301.3.1166","volume":"301","author":"Mottola","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M414090200_bib6","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1124\/jpet.301.3.1179","volume":"301","author":"Kilts","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M414090200_bib7","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1002\/j.1460-2075.1994.tb06385.x","volume":"13","author":"Robb","year":"1994","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M414090200_bib8","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.tips.2004.02.012","volume":"25","author":"Kenakin","year":"2004","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1074\/jbc.M414090200_bib9","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0163-7258(03)00051-2","volume":"99","author":"Hermans","year":"2003","journal-title":"Pharmacol. Ther."},{"key":"10.1074\/jbc.M414090200_bib10","first-page":"34","volume":"298","author":"Andrade-Gordon","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M414090200_bib11","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1139\/y01-013","volume":"79","author":"Hollenberg","year":"2001","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib12","doi-asserted-by":"crossref","first-page":"9208","DOI":"10.1073\/pnas.91.20.9208","volume":"91","author":"Nystedt","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M414090200_bib13","doi-asserted-by":"crossref","first-page":"211","DOI":"10.5551\/jat.10.211","volume":"10","author":"Hirano","year":"2003","journal-title":"J. Atheroscler. Thromb."},{"key":"10.1074\/jbc.M414090200_bib14","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1038\/386502a0","volume":"386","author":"Ishihara","year":"1997","journal-title":"Nature"},{"key":"10.1074\/jbc.M414090200_bib15","doi-asserted-by":"crossref","first-page":"13502","DOI":"10.1074\/jbc.275.18.13502","volume":"275","author":"O'Brien","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib16","doi-asserted-by":"crossref","first-page":"15061","DOI":"10.1074\/jbc.273.24.15061","volume":"273","author":"Schmidt","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib17","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1038\/35007085","volume":"404","author":"Nakanishi-Matsui","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M414090200_bib18","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1074\/jbc.272.4.2223","volume":"272","author":"Barr","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib19","doi-asserted-by":"crossref","first-page":"34143","DOI":"10.1074\/jbc.M204477200","volume":"277","author":"Vanhauwe","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib20","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1055\/s-2007-1002425","volume":"18","author":"Malik","year":"1992","journal-title":"Semin. Thromb. Hemostasis"},{"key":"10.1074\/jbc.M414090200_bib21","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1093\/oxfordjournals.bmb.a072935","volume":"50","author":"Rabiet","year":"1994","journal-title":"Br. Med. Bull."},{"key":"10.1074\/jbc.M414090200_bib22","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1161\/01.ATV.16.3.488","volume":"16","author":"Rabiet","year":"1996","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1074\/jbc.M414090200_bib23","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1126\/science.280.5372.2109","volume":"280","author":"Kozasa","year":"1998","journal-title":"Science"},{"key":"10.1074\/jbc.M414090200_bib24","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0014-5793(00)02224-9","volume":"485","author":"Fukuhara","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M414090200_bib25","doi-asserted-by":"crossref","first-page":"5868","DOI":"10.1074\/jbc.274.9.5868","volume":"274","author":"Fukuhara","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib26","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1038\/35065091","volume":"410","author":"Jackson","year":"2001","journal-title":"Nature"},{"key":"10.1074\/jbc.M414090200_bib27","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1537-1891(03)00008-9","volume":"39","author":"Wojciak-Stothard","year":"2002","journal-title":"Vasc. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib28","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S1537-1891(03)00007-7","volume":"39","author":"Tiruppathi","year":"2002","journal-title":"Vasc. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib29","first-page":"L983","volume":"280","author":"Borbiev","year":"2001","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M414090200_bib30","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1161\/01.RES.87.4.335","volume":"87","author":"van Nieuw Amerongen","year":"2000","journal-title":"Circ. Res."},{"key":"10.1074\/jbc.M414090200_bib31","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1023\/A:1013904231324","volume":"67","author":"Bogatcheva","year":"2002","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1074\/jbc.M414090200_bib32","doi-asserted-by":"crossref","first-page":"13146","DOI":"10.1016\/S0021-9258(18)42184-9","volume":"267","author":"Scarborough","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib33","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/jcp.1041560313","volume":"156","author":"Garcia","year":"1993","journal-title":"J. Cell. Physiol."},{"key":"10.1074\/jbc.M414090200_bib34","doi-asserted-by":"crossref","first-page":"16466","DOI":"10.1074\/jbc.271.28.16466","volume":"271","author":"Blackhart","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib35","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1091\/mbc.3.1.95","volume":"3","author":"Vouret-Craviari","year":"1992","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M414090200_bib36","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1042\/bj2890209","volume":"289","author":"Vouret-Craviari","year":"1993","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M414090200_bib37","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1124\/mol.58.6.1178","volume":"58","author":"Blackhart","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib38","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1124\/mol.58.6.1175","volume":"58","author":"Hollenberg","year":"2000","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib39","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1124\/jpet.302.3.1046","volume":"302","author":"Al-Ani","year":"2002","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M414090200_bib40","author":"Riewald","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib41","doi-asserted-by":"crossref","first-page":"7919","DOI":"10.1073\/pnas.89.17.7919","volume":"89","author":"Tiruppathi","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M414090200_bib42","doi-asserted-by":"crossref","first-page":"21617","DOI":"10.1016\/S0021-9258(19)36656-6","volume":"267","author":"McCarthy","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib43","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/1097-4644(20010401)81:1<93::AID-JCB1026>3.0.CO;2-I","volume":"81","author":"Kim","year":"2001","journal-title":"J. Cell. Biochem."},{"key":"10.1074\/jbc.M414090200_bib44","first-page":"538","volume":"11","author":"Rajagopalan-Gupta","year":"1997","journal-title":"Mol. Endocrinol."},{"key":"10.1074\/jbc.M414090200_bib45","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.yexcr.2004.09.020","volume":"303","author":"Harrell","year":"2005","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M414090200_bib46","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/ng1413","volume":"36","author":"Mohammed","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M414090200_bib47","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/emboj\/18.3.578","volume":"18","author":"Ren","year":"1999","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M414090200_bib48","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1042\/bj3141009","volume":"314","author":"Bohm","year":"1996","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M414090200_bib49","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1139\/y97-110","volume":"75","author":"Hollenberg","year":"1997","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib50","doi-asserted-by":"crossref","first-page":"19728","DOI":"10.1074\/jbc.M909960199","volume":"275","author":"Faruqi","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib51","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S1050-1738(99)00005-5","volume":"9","author":"Cupit","year":"1999","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1074\/jbc.M414090200_bib52","doi-asserted-by":"crossref","first-page":"14322","DOI":"10.1016\/S0021-9258(19)85244-4","volume":"268","author":"Rasmussen","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib53","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1074\/jbc.270.3.1057","volume":"270","author":"Negrescu","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib54","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1182\/blood.V94.5.1665","volume":"94","author":"Bauer","year":"1999","journal-title":"Blood"},{"key":"10.1074\/jbc.M414090200_bib55","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1055\/s-0037-1615689","volume":"85","author":"Bauer","year":"2001","journal-title":"Thromb. Haemostasis"},{"key":"10.1074\/jbc.M414090200_bib56","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/S0049-3848(01)00334-6","volume":"103","author":"Otterdal","year":"2001","journal-title":"Thromb. Res."},{"key":"10.1074\/jbc.M414090200_bib57","doi-asserted-by":"crossref","first-page":"47588","DOI":"10.1074\/jbc.M208778200","volume":"277","author":"Dorsam","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib58","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1111\/j.1538-7836.2004.00741.x","volume":"2","author":"Quinton","year":"2004","journal-title":"J Thromb. Haemostasis"},{"key":"10.1074\/jbc.M414090200_bib59","first-page":"787","volume":"74","author":"Lum","year":"1996","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib60","doi-asserted-by":"crossref","first-page":"17901","DOI":"10.1074\/jbc.274.25.17901","volume":"274","author":"Gohla","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib61","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1126\/science.280.5372.2112","volume":"280","author":"Hart","year":"1998","journal-title":"Science"},{"key":"10.1074\/jbc.M414090200_bib62","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0165-6147(99)01440-6","volume":"21","author":"Cocks","year":"2000","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1074\/jbc.M414090200_bib63","doi-asserted-by":"crossref","first-page":"15563","DOI":"10.1021\/bi9811258","volume":"37","author":"Runnels","year":"1998","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M414090200_bib64","doi-asserted-by":"crossref","first-page":"4066","DOI":"10.1093\/emboj\/17.14.4066","volume":"17","author":"Stam","year":"1998","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M414090200_bib65","doi-asserted-by":"crossref","first-page":"33492","DOI":"10.1074\/jbc.M302401200","volume":"278","author":"Mehta","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib66","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0006-2952(96)00735-6","volume":"53","author":"Schaeffer","year":"1997","journal-title":"Biochem. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib67","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1042\/bj3030227","volume":"303","author":"Herbert","year":"1994","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M414090200_bib68","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1006\/excr.1998.4372","volume":"247","author":"Sower","year":"1999","journal-title":"Exp. Cell Res."},{"key":"10.1074\/jbc.M414090200_bib69","doi-asserted-by":"crossref","first-page":"C1185","DOI":"10.1152\/ajpcell.00126.2002","volume":"284","author":"Seymour","year":"2003","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M414090200_bib70","first-page":"853","volume":"42","author":"Behzadian","year":"2001","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1074\/jbc.M414090200_bib71","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1042\/bj3570107","volume":"357","author":"Lafleur","year":"2001","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M414090200_bib72","doi-asserted-by":"crossref","first-page":"7278","DOI":"10.1074\/jbc.M208819200","volume":"278","author":"Zhong","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib73","doi-asserted-by":"crossref","first-page":"4850","DOI":"10.1523\/JNEUROSCI.22-12-04850.2002","volume":"22","author":"Hofer","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M414090200_bib74","doi-asserted-by":"crossref","first-page":"9895","DOI":"10.1073\/pnas.89.20.9895","volume":"89","author":"De Young","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M414090200_bib75","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0022-5193(03)00079-1","volume":"223","author":"Lemon","year":"2003","journal-title":"J. Theor. Biol."},{"key":"10.1074\/jbc.M414090200_bib76","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1432-1033.1995.tb20784.x","volume":"232","author":"Nystedt","year":"1995","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M414090200_bib77","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1161\/01.RES.0000057386.15390.A3","volume":"92","author":"Klarenbach","year":"2003","journal-title":"Circ. Res."},{"key":"10.1074\/jbc.M414090200_bib78","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1365-201X.1998.tb10699.x","volume":"164","author":"Stull","year":"1998","journal-title":"Acta Physiol. Scand."},{"key":"10.1074\/jbc.M414090200_bib79","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/j.1749-6632.1980.tb29607.x","volume":"356","author":"Adelstein","year":"1980","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1074\/jbc.M414090200_bib80","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1126\/science.273.5272.245","volume":"273","author":"Kimura","year":"1996","journal-title":"Science"},{"key":"10.1074\/jbc.M414090200_bib81","doi-asserted-by":"crossref","first-page":"10099","DOI":"10.1074\/jbc.273.17.10099","volume":"273","author":"Majumdar","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib82","doi-asserted-by":"crossref","first-page":"26815","DOI":"10.1074\/jbc.274.38.26815","volume":"274","author":"Majumdar","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib83","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/(SICI)1096-9896(200002)190:3<360::AID-PATH574>3.0.CO;2-8","volume":"190","author":"Preissner","year":"2000","journal-title":"J. Pathol."},{"key":"10.1074\/jbc.M414090200_bib84","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1055\/s-0037-1615076","volume":"79","author":"Lafay","year":"1998","journal-title":"Thromb. Haemostasis"},{"key":"10.1074\/jbc.M414090200_bib85","first-page":"234","volume":"35","author":"Maruyama","year":"1994","journal-title":"Rinsho Ketsueki"},{"key":"10.1074\/jbc.M414090200_bib86","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1124\/mol.65.1.149","volume":"65","author":"Al-Ani","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib87","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0065-3233(08)60481-7","volume":"30","author":"Cuatrecasas","year":"1976","journal-title":"Adv. Protein Chem."},{"key":"10.1074\/jbc.M414090200_bib88","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0022-5193(76)80126-9","volume":"58","author":"de Haen","year":"1976","journal-title":"J. Theor. Biol."},{"key":"10.1074\/jbc.M414090200_bib89","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0303-7207(77)90074-0","volume":"7","author":"Boeynaems","year":"1977","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1074\/jbc.M414090200_bib90","first-page":"1218","volume":"297","author":"Seifert","year":"2001","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1074\/jbc.M414090200_bib91","doi-asserted-by":"crossref","first-page":"8469","DOI":"10.1073\/pnas.151239698","volume":"98","author":"Peleg","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M414090200_bib92","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1074\/jbc.M310888200","volume":"279","author":"Swaminath","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib93","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1124\/mol.66.1.97","volume":"66","author":"Gay","year":"2004","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib94","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0076-6879(04)89005-0","volume":"389","author":"Hains","year":"2004","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M414090200_bib95","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/0470846674.ch2","volume":"239","author":"Bhalla","year":"2001","journal-title":"Novartis Found. Symp."},{"key":"10.1074\/jbc.M414090200_bib96","first-page":"L99","volume":"269","author":"Verin","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M414090200_bib97","doi-asserted-by":"crossref","first-page":"46506","DOI":"10.1074\/jbc.M308432200","volume":"278","author":"Hao","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib98","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.pharmthera.2003.09.003","volume":"100","author":"Ishida","year":"2003","journal-title":"Pharmacol. Ther."},{"key":"10.1074\/jbc.M414090200_bib99","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1146\/annurev.biochem.67.1.653","volume":"67","author":"Pitcher","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M414090200_bib100","doi-asserted-by":"crossref","first-page":"9780","DOI":"10.1016\/S0021-9258(18)98415-2","volume":"268","author":"Ishii","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib101","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1365-2567.2004.01870.x","volume":"112","author":"Hansen","year":"2004","journal-title":"Immunology"},{"key":"10.1074\/jbc.M414090200_bib102","doi-asserted-by":"crossref","first-page":"C36","DOI":"10.1152\/ajpcell.1995.268.1.C36","volume":"268","author":"Kruse","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M414090200_bib103","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/jcp.10280","volume":"196","author":"Faraut","year":"2003","journal-title":"J. Cell. Physiol."},{"key":"10.1074\/jbc.M414090200_bib104","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1124\/mol.51.2.350","volume":"51","author":"Ahn","year":"1997","journal-title":"Mol. Pharmacol."},{"key":"10.1074\/jbc.M414090200_bib105","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1042\/bj3200335","volume":"320","author":"Parry","year":"1996","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M414090200_bib106","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S1357-2725(98)00011-9","volume":"30","author":"Goldsack","year":"1998","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1074\/jbc.M414090200_bib107","doi-asserted-by":"crossref","first-page":"7999","DOI":"10.1074\/jbc.271.14.7999","volume":"271","author":"Biddlecome","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib108","doi-asserted-by":"crossref","first-page":"9539","DOI":"10.1073\/pnas.96.17.9539","volume":"96","author":"Mukhopadhyay","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M414090200_bib109","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1146\/annurev.biochem.69.1.795","volume":"69","author":"Ross","year":"2000","journal-title":"Annu. Rev. Biochem."},{"key":"10.1074\/jbc.M414090200_bib110","doi-asserted-by":"crossref","first-page":"23069","DOI":"10.1016\/S0021-9258(18)50057-0","volume":"267","author":"Blank","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib111","doi-asserted-by":"crossref","first-page":"19796","DOI":"10.1016\/S0021-9258(17)32090-2","volume":"269","author":"Singer","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib112","doi-asserted-by":"crossref","first-page":"9926","DOI":"10.1016\/S0021-9258(19)81606-X","volume":"263","author":"Yamamoto","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M414090200_bib113","first-page":"L595","volume":"263","author":"Tiruppathi","year":"1992","journal-title":"Am. J. Physiol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820656563?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820656563?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M414090200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T11:09:47Z","timestamp":1706180987000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820656563"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7]]},"references-count":113,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2005,7]]}},"alternative-id":["S0021925820656563"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m414090200","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1025784.305777","asserted-by":"object"}]},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2005,7]]}}}