{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:35:12Z","timestamp":1791272112081,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"39","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,9]],"date-time":"2020-10-09T00:00:00Z","timestamp":1602201600000},"content-version":"vor","delay-in-days":5152,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2006,9]]},"DOI":"10.1074\/jbc.m605122200","type":"journal-article","created":{"date-parts":[[2006,8,2]],"date-time":"2006-08-02T18:47:47Z","timestamp":1154544467000},"page":"29369-29378","source":"Crossref","is-referenced-by-count":56,"title":["Modulation of Acid-sensing Ion Channel Currents, Acid-induced Increase of Intracellular Ca2+, and Acidosis-mediated Neuronal Injury by Intracellular pH"],"prefix":"10.1016","volume":"281","author":[{"given":"Wei-Zhen","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiang-Ping","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Seeds","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger P.","family":"Simon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-Gang","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M605122200_bib1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/386173a0","volume":"386","author":"Waldmann","year":"1997","journal-title":"Nature"},{"key":"10.1074\/jbc.M605122200_bib2","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1016\/0306-4522(81)90105-6","volume":"6","author":"Krishtal","year":"1981","journal-title":"Neuroscience"},{"key":"10.1074\/jbc.M605122200_bib3","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0166-2236(03)00210-8","volume":"26","author":"Krishtal","year":"2003","journal-title":"Trends Neurosci."},{"key":"10.1074\/jbc.M605122200_bib4","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1038\/35039512","volume":"407","author":"Price","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M605122200_bib5","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/S0896-6273(01)00547-5","volume":"32","author":"Price","year":"2001","journal-title":"Neuron"},{"key":"10.1074\/jbc.M605122200_bib6","doi-asserted-by":"crossref","first-page":"3616","DOI":"10.1523\/JNEUROSCI.23-09-03616.2003","volume":"23","author":"Ugawa","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M605122200_bib7","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0896-6273(02)00661-X","volume":"34","author":"Wemmie","year":"2002","journal-title":"Neuron"},{"key":"10.1074\/jbc.M605122200_bib8","doi-asserted-by":"crossref","first-page":"5496","DOI":"10.1523\/JNEUROSCI.23-13-05496.2003","volume":"23","author":"Wemmie","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M605122200_bib9","doi-asserted-by":"crossref","first-page":"3621","DOI":"10.1073\/pnas.0308753101","volume":"101","author":"Wemmie","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M605122200_bib10","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.cell.2004.08.026","volume":"118","author":"Xiong","year":"2004","journal-title":"Cell"},{"key":"10.1074\/jbc.M605122200_bib11","doi-asserted-by":"crossref","first-page":"6752","DOI":"10.1073\/pnas.0308636100","volume":"101","author":"Yermolaieva","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M605122200_bib12","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.neuron.2005.10.011","volume":"48","author":"Gao","year":"2005","journal-title":"Neuron"},{"key":"10.1074\/jbc.M605122200_bib13","doi-asserted-by":"crossref","first-page":"8678","DOI":"10.1523\/JNEUROSCI.2844-04.2004","volume":"24","author":"Chu","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M605122200_bib14","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0896-6273(00)81144-7","volume":"26","author":"Askwith","year":"2000","journal-title":"Neuron"},{"key":"10.1074\/jbc.M605122200_bib15","doi-asserted-by":"crossref","first-page":"10662","DOI":"10.1523\/JNEUROSCI.22-24-10662.2002","volume":"22","author":"Mamet","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M605122200_bib16","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/S0028-3908(03)00047-9","volume":"44","author":"Deval","year":"2003","journal-title":"Neuropharmacology"},{"key":"10.1074\/jbc.M605122200_bib17","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/nn0901-869","volume":"4","author":"Immke","year":"2001","journal-title":"Nat. Neurosci."},{"key":"10.1074\/jbc.M605122200_bib18","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1113\/jphysiol.2002.020297","volume":"543","author":"Allen","year":"2002","journal-title":"J. Physiol."},{"key":"10.1074\/jbc.M605122200_bib19","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/S0196-0644(85)80055-X","volume":"14","author":"Rehncrona","year":"1985","journal-title":"Ann. Emerg. Med."},{"key":"10.1074\/jbc.M605122200_bib20","doi-asserted-by":"crossref","first-page":"R581","DOI":"10.1152\/ajpcell.1991.260.3.C581","volume":"260","author":"Nedergaard","year":"1991","journal-title":"Am. J. Physiol."},{"key":"10.1074\/jbc.M605122200_bib21","doi-asserted-by":"crossref","first-page":"18296","DOI":"10.1074\/jbc.M312145200","volume":"279","author":"Askwith","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M605122200_bib22","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1002\/1531-8249(200004)47:4<485::AID-ANA12>3.0.CO;2-8","volume":"47","author":"Back","year":"2000","journal-title":"Ann. Neurol."},{"key":"10.1074\/jbc.M605122200_bib23","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1113\/jphysiol.2003.043091","volume":"550","author":"Chu","year":"2003","journal-title":"J. Physiol."},{"key":"10.1074\/jbc.M605122200_bib24","doi-asserted-by":"crossref","first-page":"3925","DOI":"10.1016\/S0042-6989(96)00129-0","volume":"36","author":"Dixon","year":"1996","journal-title":"Vision Res."},{"key":"10.1074\/jbc.M605122200_bib25","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000159136","volume":"33","author":"Schubert","year":"1996","journal-title":"J. Vasc. Res."},{"key":"10.1074\/jbc.M605122200_bib26","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1113\/jphysiol.1980.sp013337","volume":"304","author":"Deitmer","year":"1980","journal-title":"J. Physiol."},{"key":"10.1074\/jbc.M605122200_bib27","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1085\/jgp.67.1.91","volume":"67","author":"Boron","year":"1976","journal-title":"J. Gen. Physiol."},{"key":"10.1074\/jbc.M605122200_bib28","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1016\/S0028-3908(00)00033-2","volume":"39","author":"Bonnet","year":"2000","journal-title":"Neuropharmacology"},{"key":"10.1074\/jbc.M605122200_bib29","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1152\/physrev.1981.61.2.296","volume":"61","author":"Roos","year":"1981","journal-title":"Physiol. Rev."},{"key":"10.1074\/jbc.M605122200_bib30","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1113\/jphysiol.1981.sp013616","volume":"312","author":"Sharp","year":"1981","journal-title":"J. Physiol."},{"key":"10.1074\/jbc.M605122200_bib31","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/0896-6273(88)90162-6","volume":"1","author":"Choi","year":"1988","journal-title":"Neuron"},{"key":"10.1074\/jbc.M605122200_bib32","doi-asserted-by":"crossref","first-page":"41597","DOI":"10.1074\/jbc.M205877200","volume":"277","author":"Babini","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M605122200_bib33","doi-asserted-by":"crossref","first-page":"3451","DOI":"10.1046\/j.1460-9568.1998.00358.x","volume":"10","author":"Obeidat","year":"1998","journal-title":"Eur. J. Neurosci"},{"key":"10.1074\/jbc.M605122200_bib34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0165-0173(01)00081-9","volume":"38","author":"Gorji","year":"2001","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1074\/jbc.M605122200_bib35","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/jcbfm.1984.3","volume":"4","author":"Mutch","year":"1984","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1074\/jbc.M605122200_bib36","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/0006-8993(94)91835-X","volume":"641","author":"Gault","year":"1994","journal-title":"Brain Res."},{"key":"10.1074\/jbc.M605122200_bib37","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0301-0082(90)90034-E","volume":"34","author":"Chesler","year":"1990","journal-title":"Prog. Neurobiol."},{"key":"10.1074\/jbc.M605122200_bib38","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0034-5687(88)90144-2","volume":"74","author":"Fievet","year":"1988","journal-title":"Respir. Physiol."},{"key":"10.1074\/jbc.M605122200_bib39","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1085\/jgp.51.2.221","volume":"51","author":"Hille","year":"1968","journal-title":"J. Gen. Physiol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192581934030X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002192581934030X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M605122200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,2]],"date-time":"2022-01-02T13:03:26Z","timestamp":1641128606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002192581934030X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":39,"journal-issue":{"issue":"39","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["S002192581934030X"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m605122200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2006,9]]}}}