{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T18:21:44Z","timestamp":1787941304731,"version":"build-2784847793"},"reference-count":48,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"vor","delay-in-days":4981,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1074\/jbc.m605986200","type":"journal-article","created":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T01:13:04Z","timestamp":1164935584000},"page":"5682-5690","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["The Nuclease A-Inhibitor Complex Is Characterized by a Novel Metal Ion Bridge"],"prefix":"10.1016","volume":"282","author":[{"given":"Mahua","family":"Ghosh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Meiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred M.","family":"Pingoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert E.","family":"London","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars C.","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M605986200_bib1","author":"Linn","year":"1993","journal-title":"Nucleases, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY"},{"key":"10.1074\/jbc.M605986200_bib2","author":"D'Alessio","year":"1997","journal-title":"Ribonucleases: Structures and Functions"},{"key":"10.1074\/jbc.M605986200_bib3","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1574-6976.2001.tb00593.x","volume":"25","author":"Rangarajan","year":"2001","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1074\/jbc.M605986200_bib4","doi-asserted-by":"crossref","DOI":"10.1385\/1592592333","author":"Schein","year":"2001","journal-title":"Nuclease Methods and Protocols"},{"key":"10.1074\/jbc.M605986200_bib5","doi-asserted-by":"crossref","first-page":"3481","DOI":"10.1093\/nar\/6.11.3481","volume":"6","author":"Krupp","year":"1979","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M605986200_bib6","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1126\/science.1092385","volume":"303","author":"Brinkmann","year":"2004","journal-title":"Science"},{"key":"10.1074\/jbc.M605986200_bib7","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.cub.2006.01.056","volume":"16","author":"Beiter","year":"2006","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M605986200_bib8","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.cub.2005.12.039","volume":"16","author":"Buchanan","year":"2006","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M605986200_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-5793(99)01499-4","volume":"463","author":"Kuhlmann","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1074\/jbc.M605986200_bib10","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/27952","volume":"394","author":"Flick","year":"1998","journal-title":"Nature"},{"key":"10.1074\/jbc.M605986200_bib11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.str.2004.01.004","volume":"12","author":"Hsia","year":"2004","journal-title":"Structure (Camb.)"},{"key":"10.1074\/jbc.M605986200_bib12","doi-asserted-by":"crossref","first-page":"34763","DOI":"10.1074\/jbc.M403719200","volume":"279","author":"Mate","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M605986200_bib13","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jmb.2004.07.032","volume":"342","author":"Shen","year":"2004","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib14","doi-asserted-by":"crossref","first-page":"5213","DOI":"10.1016\/S0021-9258(18)63648-8","volume":"244","author":"Nestle","year":"1969","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M605986200_bib15","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0022-2836(05)80259-1","volume":"213","author":"Puyet","year":"1990","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib16","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1042\/bj3390261","volume":"339","author":"Ho","year":"1999","journal-title":"Biochem. J."},{"key":"10.1074\/jbc.M605986200_bib17","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1046\/j.1432-1327.1998.2560112.x","volume":"256","author":"Ho","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1074\/jbc.M605986200_bib18","doi-asserted-by":"crossref","first-page":"3297","DOI":"10.1093\/nar\/16.8.3297","volume":"16","author":"Vincent","year":"1988","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M605986200_bib19","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1016\/S0021-9258(18)94066-4","volume":"264","author":"Cote","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M605986200_bib20","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1111\/j.1365-2958.1992.tb01760.x","volume":"6","author":"Muro-Pastor","year":"1992","journal-title":"Mol. Microbiol."},{"key":"10.1074\/jbc.M605986200_bib21","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1006\/jmbi.2000.3586","volume":"297","author":"Meiss","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib22","doi-asserted-by":"crossref","first-page":"27990","DOI":"10.1074\/jbc.M501798200","volume":"280","author":"Ghosh","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M605986200_bib23","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1006\/jmbi.1999.2729","volume":"288","author":"Miller","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib24","doi-asserted-by":"crossref","first-page":"4971","DOI":"10.1093\/nar\/20.19.4971","volume":"20","author":"Ball","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"10.1074\/jbc.M605986200_bib25","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0969-2126(93)90018-C","volume":"1","author":"Guillet","year":"1993","journal-title":"Structure (Camb.)"},{"key":"10.1074\/jbc.M605986200_bib26","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1006\/jmbi.1996.0694","volume":"264","author":"Kobe","year":"1996","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib27","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0969-2126(99)80012-4","volume":"7","author":"Ko","year":"1999","journal-title":"Structure (Camb.)"},{"key":"10.1074\/jbc.M605986200_bib28","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1042\/bst0270063","volume":"27","author":"Kleanthous","year":"1999","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M605986200_bib29","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/S0022-2836(02)00460-6","volume":"320","author":"Kirby","year":"2002","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib30","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1006\/abio.2000.4685","volume":"286","author":"Kuzmic","year":"2000","journal-title":"Anal. Biochem."},{"key":"10.1074\/jbc.M605986200_bib31","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/0076-6879(79)63019-7","volume":"63","author":"Williams","year":"1979","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M605986200_bib32","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1107\/S0021889897006766","volume":"30","author":"Vagin","year":"1997","journal-title":"J. Appl. Crystallogr."},{"key":"10.1074\/jbc.M605986200_bib33","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1107\/S0907444993011898","volume":"50","author":"Bailey","year":"1994","journal-title":"Acta Crystallogr. Sect. D"},{"key":"10.1074\/jbc.M605986200_bib34","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1107\/S0108767390010224","volume":"47","author":"Jones","year":"1991","journal-title":"Acta Crystallogr. Sect. A"},{"key":"10.1074\/jbc.M605986200_bib35","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1107\/S0907444998003254","volume":"54","author":"Bru\u00f6nger","year":"1998","journal-title":"Acta Crystallogr. Sect. D"},{"key":"10.1074\/jbc.M605986200_bib36","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1107\/S0021889892009944","volume":"26","author":"Laskowski","year":"1993","journal-title":"J. Appl. Crystallogr."},{"key":"10.1074\/jbc.M605986200_bib37","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1002\/prot.10286","volume":"50","author":"Lovell","year":"2003","journal-title":"Proteins"},{"key":"10.1074\/jbc.M605986200_bib38","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1110\/ps.8.8.1711","volume":"8","author":"Hannan","year":"1999","journal-title":"Protein Sci."},{"key":"10.1074\/jbc.M605986200_bib39","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1006\/jmbi.1997.1284","volume":"273","author":"Guntert","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib40","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0022-2836(02)00241-3","volume":"319","author":"Herrmann","year":"2002","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M605986200_bib41","doi-asserted-by":"crossref","first-page":"4014","DOI":"10.1093\/emboj\/cdg377","volume":"22","author":"Li","year":"2003","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M605986200_bib42","doi-asserted-by":"crossref","first-page":"779","DOI":"10.2174\/0929867033457845","volume":"10","author":"Loverix","year":"2003","journal-title":"Curr. Med. Chem."},{"key":"10.1074\/jbc.M605986200_bib43","first-page":"183","volume":"4","author":"Klarmann","year":"2002","journal-title":"AIDS Rev."},{"key":"10.1074\/jbc.M605986200_bib44","doi-asserted-by":"crossref","first-page":"8878","DOI":"10.1021\/bi00196a004","volume":"33","author":"Buckle","year":"1994","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M605986200_bib45","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/374381a0","volume":"374","author":"Mol","year":"1995","journal-title":"Nature"},{"key":"10.1074\/jbc.M605986200_bib46","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1042\/BST0340317","volume":"34","author":"Dryden","year":"2006","journal-title":"Biochem. Soc. Trans."},{"key":"10.1074\/jbc.M605986200_bib47","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0968-0004(01)01941-7","volume":"26","author":"Kleanthous","year":"2001","journal-title":"Trends Biochem. Sci."},{"key":"10.1074\/jbc.M605986200_bib48","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/nchembio797","volume":"2","author":"Banci","year":"2006","journal-title":"Nat. Chem. Biol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820688640?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820688640?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M605986200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T11:41:22Z","timestamp":1641382882000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820688640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":48,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S0021925820688640"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m605986200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Nuclease A-Inhibitor Complex Is Characterized by a Novel Metal Ion Bridge","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M605986200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2007 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}