{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T07:32:34Z","timestamp":1785310354298,"version":"3.55.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,15]],"date-time":"2020-09-15T00:00:00Z","timestamp":1600128000000},"content-version":"vor","delay-in-days":4886,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1074\/jbc.m700971200","type":"journal-article","created":{"date-parts":[[2007,3,31]],"date-time":"2007-03-31T00:13:37Z","timestamp":1175300017000},"page":"14861-14867","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Stringent 3Q\u00b71R Composition of the SNARE 0-Layer Can Be Bypassed for Fusion by Compensatory SNARE Mutation or by Lipid Bilayer Modification"],"prefix":"10.1016","volume":"282","author":[{"given":"Rutilio A.","family":"Fratti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin M.","family":"Collins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Hickey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Wickner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M700971200_bib1","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/nrm2002","volume":"7","author":"Jahn","year":"2006","journal-title":"Nat. Rev. Mol. Cell Biol"},{"key":"10.1074\/jbc.M700971200_bib2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/26412","volume":"395","author":"Sutton","year":"1998","journal-title":"Nature"},{"key":"10.1074\/jbc.M700971200_bib3","doi-asserted-by":"crossref","first-page":"10354","DOI":"10.1021\/bi980542h","volume":"37","author":"Fasshauer","year":"1998","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M700971200_bib4","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/0092-8674(93)90376-2","volume":"75","author":"So\u00f6llner","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.M700971200_bib5","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0092-8674(00)81404-X","volume":"92","author":"Weber","year":"1998","journal-title":"Cell"},{"key":"10.1074\/jbc.M700971200_bib6","doi-asserted-by":"crossref","first-page":"12571","DOI":"10.1073\/pnas.96.22.12571","volume":"96","author":"Nickel","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M700971200_bib7","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1529\/biophysj.105.069617","volume":"90","author":"Dennison","year":"2006","journal-title":"Biophys. J."},{"key":"10.1074\/jbc.M700971200_bib8","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1529\/biophysj.105.071415","volume":"90","author":"Chen","year":"2006","journal-title":"Biophys. J."},{"key":"10.1074\/jbc.M700971200_bib9","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/35025000","volume":"407","author":"McNew","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M700971200_bib10","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1126\/science.1097196","volume":"304","author":"Tucker","year":"2004","journal-title":"Science"},{"key":"10.1074\/jbc.M700971200_bib11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1083\/jcb.200405018","volume":"167","author":"Scott","year":"2004","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib12","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1038\/nsmb1076","volume":"13","author":"Bhalla","year":"2006","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1074\/jbc.M700971200_bib13","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/387199a0","volume":"387","author":"Nichols","year":"1997","journal-title":"Nature"},{"key":"10.1074\/jbc.M700971200_bib14","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1083\/jcb.119.6.1469","volume":"119","author":"Conradt","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0960-9822(98)00060-8","volume":"8","author":"Bone","year":"1998","journal-title":"Curr. Biol."},{"key":"10.1074\/jbc.M700971200_bib16","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1083\/jcb.126.1.87","volume":"126","author":"Haas","year":"1994","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib17","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1083\/jcb.140.1.61","volume":"140","author":"Ungermann","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib18","doi-asserted-by":"crossref","first-page":"5258","DOI":"10.1002\/j.1460-2075.1995.tb00210.x","volume":"14","author":"Haas","year":"1995","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M700971200_bib19","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1038\/sj.emboj.7601051","volume":"25","author":"Stroupe","year":"2006","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M700971200_bib20","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/S1097-2765(00)00064-2","volume":"6","author":"Sato","year":"2000","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M700971200_bib21","doi-asserted-by":"crossref","first-page":"9402","DOI":"10.1073\/pnas.97.17.9402","volume":"97","author":"Seals","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M700971200_bib22","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0092-8674(02)00632-3","volume":"108","author":"Wang","year":"2002","journal-title":"Cell"},{"key":"10.1074\/jbc.M700971200_bib23","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1083\/jcb.200204089","volume":"158","author":"Eitzen","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib24","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1083\/jcb.200209095","volume":"160","author":"Wang","year":"2003","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib25","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1083\/jcb.200409068","volume":"167","author":"Fratti","year":"2004","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib26","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1038\/sj.emboj.7600658","volume":"24","author":"Collins","year":"2005","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M700971200_bib27","doi-asserted-by":"crossref","first-page":"11548","DOI":"10.1073\/pnas.0404583101","volume":"101","author":"Merz","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M700971200_bib28","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1083\/jcb.145.7.1435","volume":"145","author":"Ungermann","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib29","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1038\/35025084","volume":"407","author":"Fukuda","year":"2000","journal-title":"Nature"},{"key":"10.1074\/jbc.M700971200_bib30","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1038\/sj.emboj.7600286","volume":"23","author":"Thorngren","year":"2004","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M700971200_bib31","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0092-8674(00)81710-9","volume":"95","author":"Skehel","year":"1998","journal-title":"Cell"},{"key":"10.1074\/jbc.M700971200_bib32","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1083\/jcb.150.1.105","volume":"150","author":"McNew","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib33","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1006\/jmbi.2001.4889","volume":"311","author":"Langosch","year":"2001","journal-title":"J. Mol. Biol."},{"key":"10.1074\/jbc.M700971200_bib34","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1529\/biophysj.105.070466","volume":"90","author":"Siegel","year":"2006","journal-title":"Biophys. J."},{"key":"10.1074\/jbc.M700971200_bib35","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1126\/science.1095801","volume":"304","author":"Han","year":"2004","journal-title":"Science"},{"key":"10.1074\/jbc.M700971200_bib36","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/35083000","volume":"3","author":"Cheever","year":"2001","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M700971200_bib37","doi-asserted-by":"crossref","first-page":"15781","DOI":"10.1073\/pnas.95.26.15781","volume":"95","author":"Fasshauer","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M700971200_bib38","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0076-6879(02)51844-9","volume":"351","author":"Jones","year":"2002","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M700971200_bib39","doi-asserted-by":"crossref","first-page":"680","DOI":"10.2144\/99264st03","volume":"26","author":"Wang","year":"1999","journal-title":"BioTechniques"},{"key":"10.1074\/jbc.M700971200_bib40","doi-asserted-by":"crossref","first-page":"3296","DOI":"10.1002\/j.1460-2075.1996.tb00694.x","volume":"15","author":"Haas","year":"1996","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M700971200_bib41","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S0076-6879(95)57028-4","volume":"257","author":"Garrett","year":"1995","journal-title":"Methods Enzymol."},{"key":"10.1074\/jbc.M700971200_bib42","doi-asserted-by":"crossref","first-page":"5582","DOI":"10.1073\/pnas.94.11.5582","volume":"94","author":"Slusarewicz","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M700971200_bib43","doi-asserted-by":"crossref","first-page":"5260","DOI":"10.1038\/sj.emboj.7601413","volume":"25","author":"Jun","year":"2006","journal-title":"EMBO J."},{"key":"10.1074\/jbc.M700971200_bib44","doi-asserted-by":"crossref","first-page":"14262","DOI":"10.1073\/pnas.251547598","volume":"98","author":"Scales","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M700971200_bib45","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1091\/mbc.e04-09-0830","volume":"16","author":"Graf","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M700971200_bib46","doi-asserted-by":"crossref","first-page":"3849","DOI":"10.1091\/mbc.11.11.3849","volume":"11","author":"Katz","year":"2000","journal-title":"Mol. Biol. Cell"},{"key":"10.1074\/jbc.M700971200_bib47","doi-asserted-by":"crossref","first-page":"28598","DOI":"10.1074\/jbc.M101644200","volume":"276","author":"Wang","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M700971200_bib48","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1126\/science.287.5453.658","volume":"287","author":"Oghalai","year":"2000","journal-title":"Science"},{"key":"10.1074\/jbc.M700971200_bib49","doi-asserted-by":"crossref","first-page":"4090","DOI":"10.1529\/biophysj.105.069872","volume":"89","author":"Murdock","year":"2005","journal-title":"Biophys. J."},{"key":"10.1074\/jbc.M700971200_bib50","doi-asserted-by":"crossref","first-page":"3759","DOI":"10.1242\/jcs.114.20.3759","volume":"114","author":"Raucher","year":"2001","journal-title":"J. Cell Sci."},{"key":"10.1074\/jbc.M700971200_bib51","doi-asserted-by":"crossref","first-page":"53186","DOI":"10.1074\/jbc.M411363200","volume":"279","author":"Jun","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M700971200_bib52","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.jmb.2006.09.077","volume":"364","author":"Hofmann","year":"2006","journal-title":"J. Mol. Biol."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820636390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820636390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M700971200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T07:32:12Z","timestamp":1641367932000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820636390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":52,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S0021925820636390"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m700971200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stringent 3Q\u00b71R Composition of the SNARE 0-Layer Can Be Bypassed for Fusion by Compensatory SNARE Mutation or by Lipid Bilayer Modification","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M700971200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2007 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}