{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:14:48Z","timestamp":1791328488797,"version":"4.3.1"},"reference-count":50,"publisher":"Elsevier BV","issue":"33","license":[{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,14]],"date-time":"2020-09-14T00:00:00Z","timestamp":1600041600000},"content-version":"vor","delay-in-days":4793,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["jbc.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1074\/jbc.m704789200","type":"journal-article","created":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T13:27:07Z","timestamp":1182000427000},"page":"24039-24048","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":91,"title":["Detection of Polyglutamine Protein Oligomers in Cells by Fluorescence Correlation Spectroscopy"],"prefix":"10.1016","volume":"282","author":[{"given":"Yasuo","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuma","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. Akiko","family":"Popiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhiro","family":"Fujikake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsushi","family":"Toda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Kinjo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshitaka","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M704789200_bib1","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.1126\/science.1067122","volume":"296","author":"Taylor","year":"2002","journal-title":"Science"},{"key":"10.1074\/jbc.M704789200_bib2","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1038\/nrm1742","volume":"6","author":"Ross","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1074\/jbc.M704789200_bib3","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0140-6736(97)02073-4","volume":"350","author":"Carrell","year":"1997","journal-title":"Lancet"},{"key":"10.1074\/jbc.M704789200_bib4","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/35039051","volume":"1","author":"Gusella","year":"2000","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1074\/jbc.M704789200_bib5","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev.neuro.23.1.217","volume":"23","author":"Zoghbi","year":"2000","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1074\/jbc.M704789200_bib6","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/nature02998","volume":"431","author":"Arrasate","year":"2004","journal-title":"Nature"},{"key":"10.1074\/jbc.M704789200_bib7","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0962-8924(00)01852-3","volume":"10","author":"Kopito","year":"2000","journal-title":"Trends Cell Biol."},{"key":"10.1074\/jbc.M704789200_bib8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nrm2101","volume":"8","author":"Haass","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1074\/jbc.M704789200_bib9","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1146\/annurev.neuro.26.010302.081142","volume":"26","author":"Caughey","year":"2003","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1074\/jbc.M704789200_bib10","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1007\/s00109-003-0464-5","volume":"81","author":"Stefani","year":"2003","journal-title":"J. Mol. Med."},{"key":"10.1074\/jbc.M704789200_bib11","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.neurobiolaging.2004.02.010","volume":"25","author":"Klein","year":"2004","journal-title":"Neurobiol. Aging"},{"key":"10.1074\/jbc.M704789200_bib12","doi-asserted-by":"crossref","first-page":"5740","DOI":"10.1073\/pnas.91.13.5740","volume":"91","author":"Eigen","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M704789200_bib13","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1034\/j.1600-0854.2001.21107.x","volume":"2","author":"Elson","year":"2001","journal-title":"Traffic"},{"key":"10.1074\/jbc.M704789200_bib14","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0092-8674(00)00094-5","volume":"103","author":"Terada","year":"2000","journal-title":"Cell"},{"key":"10.1074\/jbc.M704789200_bib15","doi-asserted-by":"crossref","first-page":"11676","DOI":"10.1021\/bi050744v","volume":"44","author":"Jankevics","year":"2005","journal-title":"Biochemistry"},{"key":"10.1074\/jbc.M704789200_bib16","doi-asserted-by":"crossref","first-page":"32586","DOI":"10.1074\/jbc.M504121200","volume":"280","author":"Hirose","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M704789200_bib17","doi-asserted-by":"crossref","first-page":"10437","DOI":"10.1074\/jbc.275.14.10437","volume":"275","author":"Nagai","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M704789200_bib18","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.bbrc.2004.03.161","volume":"317","author":"Popiel","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M704789200_bib19","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2174\/1389201053642330","volume":"6","author":"Takahashi","year":"2005","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1074\/jbc.M704789200_bib20","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1126\/science.1079469","volume":"300","author":"Kayed","year":"2003","journal-title":"Science"},{"key":"10.1074\/jbc.M704789200_bib21","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0962-8924(98)01434-2","volume":"9","author":"Pollok","year":"1999","journal-title":"Trends Cell Biol."},{"key":"10.1074\/jbc.M704789200_bib22","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/ncb863","volume":"4","author":"Kim","year":"2002","journal-title":"Nat. Cell. Biol."},{"key":"10.1074\/jbc.M704789200_bib23","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/S0896-6273(03)00697-4","volume":"40","author":"Pollitt","year":"2003","journal-title":"Neuron"},{"key":"10.1074\/jbc.M704789200_bib24","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/35073068","volume":"2","author":"Lippincott-Schwartz","year":"2001","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1074\/jbc.M704789200_bib25","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1093\/hmg\/ddg144","volume":"12","author":"Nagai","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M704789200_bib26","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/sj.mt.6300045","volume":"15","author":"Popiel","year":"2007","journal-title":"Mol. Ther."},{"key":"10.1074\/jbc.M704789200_bib27","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/nsmb1215","volume":"14","author":"Nagai","year":"2007","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1074\/jbc.M704789200_bib28","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1006\/bbrc.2001.5783","volume":"288","author":"Ren","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1074\/jbc.M704789200_bib29","doi-asserted-by":"crossref","first-page":"6739","DOI":"10.1073\/pnas.110138997","volume":"97","author":"Heiser","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M704789200_bib30","doi-asserted-by":"crossref","first-page":"41032","DOI":"10.1074\/jbc.M205809200","volume":"277","author":"Poirier","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M704789200_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1432-0436.2004.07201002.x","volume":"72","author":"Levin","year":"2004","journal-title":"Differentiation"},{"key":"10.1074\/jbc.M704789200_bib32","doi-asserted-by":"crossref","first-page":"10338","DOI":"10.1523\/JNEUROSCI.19-23-10338.1999","volume":"19","author":"Chai","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M704789200_bib33","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1006\/exnr.1998.6991","volume":"155","author":"Nagai","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1074\/jbc.M704789200_bib34","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1523\/JNEUROSCI.13-04-01676.1993","volume":"13","author":"Pike","year":"1993","journal-title":"J. Neurosci."},{"key":"10.1074\/jbc.M704789200_bib35","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1093\/hmg\/11.23.2905","volume":"11","author":"Yang","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M704789200_bib36","doi-asserted-by":"crossref","first-page":"6448","DOI":"10.1073\/pnas.95.11.6448","volume":"95","author":"Lambert","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M704789200_bib37","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/416535a","volume":"416","author":"Walsh","year":"2002","journal-title":"Nature"},{"key":"10.1074\/jbc.M704789200_bib38","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/416507a","volume":"416","author":"Bucciantini","year":"2002","journal-title":"Nature"},{"key":"10.1074\/jbc.M704789200_bib39","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/nsmb860","volume":"11","author":"Wacker","year":"2004","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1074\/jbc.M704789200_bib40","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.molcel.2004.06.029","volume":"15","author":"Schaffar","year":"2004","journal-title":"Mol. Cell"},{"key":"10.1074\/jbc.M704789200_bib41","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1038\/ng864","volume":"30","author":"Kazantsev","year":"2002","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M704789200_bib42","doi-asserted-by":"crossref","first-page":"4764","DOI":"10.1073\/pnas.071058398","volume":"98","author":"Lecerf","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M704789200_bib43","doi-asserted-by":"crossref","first-page":"17616","DOI":"10.1073\/pnas.0408134101","volume":"101","author":"Colby","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M704789200_bib44","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/502","volume":"19","author":"Cummings","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M704789200_bib45","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/70532","volume":"23","author":"Warrick","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M704789200_bib46","doi-asserted-by":"crossref","first-page":"16400","DOI":"10.1073\/pnas.182426599","volume":"99","author":"Heiser","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M704789200_bib47","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1038\/nature01301","volume":"421","author":"Sanchez","year":"2003","journal-title":"Nature"},{"key":"10.1074\/jbc.M704789200_bib48","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/nm985","volume":"10","author":"Tanaka","year":"2004","journal-title":"Nat. Med."},{"key":"10.1074\/jbc.M704789200_bib49","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1038\/ncb1478","volume":"8","author":"Kitamura","year":"2006","journal-title":"Nat. Cell Biol."},{"key":"10.1074\/jbc.M704789200_bib50","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.nbd.2006.09.015","volume":"25","author":"Wood","year":"2007","journal-title":"Neurobiol. Dis."}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820543871?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820543871?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M704789200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,5]],"date-time":"2022-01-05T01:05:19Z","timestamp":1641344719000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820543871"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":50,"journal-issue":{"issue":"33","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["S0021925820543871"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m704789200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection of Polyglutamine Protein Oligomers in Cells by Fluorescence Correlation Spectroscopy","name":"articletitle","label":"Article Title"},{"value":"Journal of Biological Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1074\/jbc.M704789200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2007 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology.","name":"copyright","label":"Copyright"}]}}