{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:50:25Z","timestamp":1789714225423,"version":"4.0.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"47","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,18]],"date-time":"2020-09-18T00:00:00Z","timestamp":1600387200000},"content-version":"vor","delay-in-days":4339,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Biological Chemistry"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1074\/jbc.m803183200","type":"journal-article","created":{"date-parts":[[2008,9,11]],"date-time":"2008-09-11T20:13:17Z","timestamp":1221163997000},"page":"32751-32761","source":"Crossref","is-referenced-by-count":32,"title":["The Boston-type Craniosynostosis Mutation MSX2 (P148H) Results in Enhanced Susceptibility of MSX2 to Ubiquitin-dependent Degradation"],"prefix":"10.1016","volume":"283","author":[{"given":"Won-Joon","family":"Yoon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Dan","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang-Hwi","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung-Mi","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Hwa","family":"Baek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Je-Yoel","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwan-Shik","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Mo","family":"Ryoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1074\/jbc.M803183200_bib1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.gene.2005.10.011","volume":"366","author":"Ryoo","year":"2006","journal-title":"Gene (Amst.)"},{"key":"10.1074\/jbc.M803183200_bib2","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0925-4773(94)90059-0","volume":"48","author":"Liu","year":"1994","journal-title":"Mech. Dev."},{"key":"10.1074\/jbc.M803183200_bib3","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1006\/dbio.1995.1210","volume":"170","author":"Sumoy","year":"1995","journal-title":"Dev. Biol."},{"key":"10.1074\/jbc.M803183200_bib4","first-page":"763","volume":"32","author":"Nishikawa","year":"1994","journal-title":"Biochem. Mol. Biol. Int."},{"key":"10.1074\/jbc.M803183200_bib5","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1002\/(SICI)1097-010X(19981215)282:6<703::AID-JEZ6>3.0.CO;2-P","volume":"282","author":"Koshiba","year":"1998","journal-title":"J. Exp. Zool."},{"key":"10.1074\/jbc.M803183200_bib6","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1006\/dbio.1994.1296","volume":"166","author":"Ros","year":"1994","journal-title":"Dev. Biol."},{"key":"10.1074\/jbc.M803183200_bib7","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/sj.jidsp.5640229","volume":"4","author":"Wang","year":"1999","journal-title":"J. Investig. Dermatol."},{"key":"10.1074\/jbc.M803183200_bib8","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1038\/74231","volume":"24","author":"Satokata","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M803183200_bib9","doi-asserted-by":"crossref","first-page":"2920","DOI":"10.1128\/MCB.17.5.2920","volume":"17","author":"Zhang","year":"1997","journal-title":"Mol. Cell Biol."},{"key":"10.1074\/jbc.M803183200_bib10","doi-asserted-by":"crossref","first-page":"16360","DOI":"10.1021\/bi981878u","volume":"37","author":"Newberry","year":"1998","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1074\/jbc.M803183200_bib11","doi-asserted-by":"crossref","first-page":"10451","DOI":"10.1021\/bi971008x","volume":"36","author":"Newberry","year":"1997","journal-title":"Biochemistry (Mosc.)"},{"key":"10.1074\/jbc.M803183200_bib12","doi-asserted-by":"crossref","first-page":"29607","DOI":"10.1074\/jbc.272.47.29607","volume":"272","author":"Newberry","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M803183200_bib13","doi-asserted-by":"crossref","first-page":"35579","DOI":"10.1074\/jbc.M502267200","volume":"280","author":"Lee","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M803183200_bib14","doi-asserted-by":"crossref","first-page":"50773","DOI":"10.1074\/jbc.M404145200","volume":"279","author":"Kim","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M803183200_bib15","doi-asserted-by":"crossref","first-page":"9248","DOI":"10.1128\/MCB.24.20.9248-9261.2004","volume":"24","author":"Hassan","year":"2004","journal-title":"Mol. Cell Biol."},{"key":"10.1074\/jbc.M803183200_bib16","doi-asserted-by":"crossref","first-page":"3460","DOI":"10.1128\/MCB.24.8.3460-3472.2004","volume":"24","author":"Yoshizawa","year":"2004","journal-title":"Mol. Cell Biol."},{"key":"10.1074\/jbc.M803183200_bib17","doi-asserted-by":"crossref","first-page":"45969","DOI":"10.1074\/jbc.M306972200","volume":"278","author":"Cheng","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M803183200_bib18","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1196\/annals.1346.036","volume":"1068","author":"Towler","year":"2006","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1074\/jbc.M803183200_bib19","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1172\/JCI24140","volume":"115","author":"Shao","year":"2005","journal-title":"J. Clin. Investig."},{"key":"10.1074\/jbc.M803183200_bib20","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1002\/ajmg.a.31946","volume":"143","author":"Wang","year":"2007","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1074\/jbc.M803183200_bib21","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1002\/ajmg.a.20552","volume":"128","author":"Shiihara","year":"2004","journal-title":"Am. J. Med. Genet. A"},{"key":"10.1074\/jbc.M803183200_bib22","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1006\/dbio.1998.9114","volume":"205","author":"Liu","year":"1999","journal-title":"Dev. Biol."},{"key":"10.1074\/jbc.M803183200_bib23","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1006\/dbio.1999.9258","volume":"209","author":"Dodig","year":"1999","journal-title":"Dev. Biol."},{"key":"10.1074\/jbc.M803183200_bib24","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1002\/ajmg.1320460420","volume":"46","author":"Warman","year":"1993","journal-title":"Am. J. Med. Genet."},{"key":"10.1074\/jbc.M803183200_bib25","doi-asserted-by":"crossref","first-page":"6137","DOI":"10.1073\/pnas.92.13.6137","volume":"92","author":"Liu","year":"1995","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M803183200_bib26","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/0092-8674(93)90379-5","volume":"75","author":"Jabs","year":"1993","journal-title":"Cell"},{"key":"10.1074\/jbc.M803183200_bib27","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1093\/hmg\/5.12.1915","volume":"5","author":"Ma","year":"1996","journal-title":"Hum. Mol. Genet."},{"key":"10.1074\/jbc.M803183200_bib28","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1359\/jbmr.2001.16.5.885","volume":"16","author":"Park","year":"2001","journal-title":"J. Bone Miner. Res."},{"key":"10.1074\/jbc.M803183200_bib29","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1242\/dev.125.7.1241","volume":"125","author":"Kim","year":"1998","journal-title":"Development"},{"key":"10.1074\/jbc.M803183200_bib30","doi-asserted-by":"crossref","first-page":"22541","DOI":"10.1074\/jbc.M109728200","volume":"277","author":"Sasaki","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1074\/jbc.M803183200_bib31","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.cell.2004.07.025","volume":"118","author":"Kozar","year":"2004","journal-title":"Cell"},{"key":"10.1074\/jbc.M803183200_bib32","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/74224","volume":"24","author":"Wilkie","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1074\/jbc.M803183200_bib33","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0012-1606(03)00355-5","volume":"262","author":"Rice","year":"2003","journal-title":"Dev. Biol."},{"key":"10.1074\/jbc.M803183200_bib34","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1073\/pnas.87.1.6","volume":"87","author":"Shew","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1074\/jbc.M803183200_bib35","first-page":"1483","volume":"4","author":"Romano","year":"1989","journal-title":"Oncogene"},{"key":"10.1074\/jbc.M803183200_bib36","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1111\/j.1365-2184.2007.00448.x","volume":"40","author":"Montanaro","year":"2007","journal-title":"Cell Prolif."},{"key":"10.1074\/jbc.M803183200_bib37","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nrc2399","volume":"8","author":"Burkhart","year":"2008","journal-title":"Nat. Rev. Cancer"}],"container-title":["Journal of Biological Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820604586?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0021925820604586?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1074\/jbc.M803183200","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,18]],"date-time":"2021-12-18T10:01:47Z","timestamp":1639821707000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0021925820604586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":37,"journal-issue":{"issue":"47","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S0021925820604586"],"URL":"https:\/\/doi.org\/10.1074\/jbc.m803183200","relation":{},"ISSN":["0021-9258"],"issn-type":[{"value":"0021-9258","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}